Conserved Protein Domain Family
GdpP

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COG3887: GdpP 
Cyclic di-AMP phosphodiesterase GdpP, contains GGDEF-like and DHH domains [Signal transduction mechanisms]
Statistics
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PSSM-Id: 443095
Aligned: 107 rows
Threshold Bit Score: 645.672
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011412290   1 MFSKnk---hnTKFIVIACVIVVLILILFCFDfqniqeiietinqltnnqnpskntasemsgmrrkiifFIFnFfG-KII 76 
WP_012242153   1 MRK-----------LINGILITLWVIAFLVFTlvtftemf---------------------nqipnikfISY-M-TfIVI 46 
WP_015777490   1 MNKEd------VYVGRENIIAIMALPALASLV-------------------------------------IFY-Y-N-QIL 34 
WP_012358749   1 MSLKk------NVKLVMAIVIVVLFLLFLRYDydniskviqqid-------------ktsdnllkarlwAAFgL-G-KII 59 
WP_038467654   1 MNKNrn----------iVILSITILLVVIVDI-------------------------------------IMM-G-N-PIF 30 
WP_041953392   1 MGK--------KLIKLSDFYVLFLFMVLISAF-------------------------------------VLY-F-Q-FIF 32 
WP_055275176   1 MKKIrkw--leEYQDHLGYLVISIVSLVVTGI-------------------------------------YAY-YqS-DVI 39 
WP_083428280  12 MNRDifs-enaQQRLWTEVLVVSIVGLLMTCG-------------------------------------LFF-W-N-AYA 50 
WP_083427735   1 MKNFweltkfgVNKYFRFSYRYILLAIVVTVI-------------------------------------LVF-L-E-PIL 40 
WP_072515124   1 MKNRrmn-gdlTQMDWRDVWVVPLLTGFLTIG-------------------------------------LFL-W-N-SMA 39 
WP_011412290  77 --LASFIIS--------FLLHIKKNAQIKRLKNKLSLWSKLSFHVSQIGEEVLNELPIGIVLIDISSqEIQWLNPYASFI 146
WP_012242153  47 tlLAVFVLI--------LTIVNNYKQYIKNLQNRLARWSKLSPRVNQVGDDAFHELPIGILVLDEGLkEIKWVNQYAKVI 118
WP_015777490  35 gsVAIILTI--------VLFFFLRNINRKKKDDFQNYVDEMNVSFDIITKNVVFEMPFPIAIVEDDR-TIKWHNTYFRDL 105
WP_012358749  60 --LIILIIS--------FVLQIKKNNKIKRLQAKLNLWSKLSFHVSQIGEEVLNELPIGIVLIDVNNkEIQWLNPYANLI 129
WP_038467654  31 vlVFSVLMFvgyniitnMLVYRYKNVQIKWLSHKLEDTKDTLDRKDKAEKRMVQDLPLGIMIYDEHL-TIKWANGYSKDI 109
WP_041953392  33 giVSFILTF--------ISFILVLYYIKNKNIEYEEDIRKYKDSLDNIASEVVYKMPFPVAVLNNKG-RVKWYSPEFSEL 103
WP_055275176  40 slIIFLYFV--------GDAIYRVNAYFHYKADTLKKIESISYRVKHAGETAFNQLPMGILLYDEAY-EIVWFNGYLKRV 110
WP_083428280  51 gvAGFVGTI--------FLSTHSYLREREAQRSVVDAIETLDLHFDEVTKNAVFGMPFPMTVLDEHG-LFLWYNSYFKEL 121
WP_083427735  41 agLLIVTLA--------FLITYDIREHDTKIKALESEKSKESEEFESVTMHAIFRMPYPLVMTDKSG-VITWQNSPFSEI 111
WP_072515124  40 gvIGVLVTG--------FLGYYTFVREKQAADRTKQAIEALNEDFDEVTKNAVFGMPFPMAVLNAAG-NFLWYNSRFKAL 110
WP_011412290 147 LKNP--EINSPLTQINENMAqL--ISTSDTIPKTII--TLKNQKFECFYKK--------DLSVFYLFDATEKEQIKHLFL 212
WP_012242153 119 FEGR--LIDRPVAEISASLAdY--LLSDNK-QPITI--SVKDQKYEVLYKD--------SFQVIYLFNVTSRENVKLEFI 183
WP_015777490 106 FDKKs-IVGSDIEKFLPDFS-DvdFKEDGMSLPKNI--SIDDKILQFYYQTitneengkTQTFLYGIDNTYDESIKQLFK 181
WP_012358749 130 LKNP--EINTPLSQINESML----LLTEQETEKTII--TLEKEKFECFYKK--------DLNVFYLFNASEKEEVKQLFR 193
WP_038467654 110 FENA--LEGRSMEMINEDIFnH--VTTKQSd-sFIT--KIYTHLYEIVVDL--------KEQIVYLTQVTEREEIKRKYD 174
WP_041953392 104 FSGSd-IVGIDINSEISSFN-IteVLKKGY---GKVnwETKKFNYLVYYNVvkdedngdVNVIIYLIDNLAYSKLKKQYE 178
WP_055275176 111 FNQd--LHDKVLKDLSEQLY-NrsLGDEES---FKI--TVNQQTYQVLHMK--------DERLMYFTDYTEYTELSRKYV 174
WP_083428280 122 FHIQdsLLGQAYDKLFADVP-VktLIGKNA-APFRV--TVGDRIYLFYNNVtssp-kgeTLILLYGVDNSEDEEVRERYQ 196
WP_083427735 112 VGEI--DRNAKLNELIPAIN-LseLEKEQKs--FNI--SYKDKYYLVRSDKvldh-gkvDRYIVYMLDVTKNRELEKAYN 183
WP_072515124 111 FHIEetFLGKSYRDVFATVS-IdtLLQKTN-VPFAV--QMDGKTFQFYHNCtdge-nheRLLLLYGVDDTENEAVRQAWR 185
WP_011412290 213 QKTLAIAMIAFDNLAESLIRYDLSEQSQIQGEYLSALSDYIEPYESYLKQLIDDRFLLLLNRQNLDKMLENKFSILDTIR 292
WP_012242153 184 KNLPAIGILNLDNFEDNMTNFDISEQTSIKGEYLSAIADWVDEYNGYLKPYGDNRMVMLIKRKRLEDMMAKKFDILEHIR 263
WP_015777490 182 DKRLVFYSVFIDNYEDIRNSTESVDRPQVIGEIDRVINEYFKKYNCLIRKYENDRYMVISEYQDYRDIYETKFSILDGVR 261
WP_012358749 194 DKSLALAMITFDHLEESLIRYDISEQSQIKGEYLRALSDFIDPYEGYLKQLLDDRFLLLVNRQNLDKMIENKFSILDTVR 273
WP_038467654 175 ASIGVIAMLNLDNLDDAVSVLDVSNRSFVQGRYLEALEAWGEEYSFYITPLTNSKLIAVMNKKRLMSLVKDEFKIVDKIA 254
WP_041953392 179 EETLNSIVIYIDNYEDVRNNVKEDFKAILIAEMDKIIINYFSSLGAIIRKYDSGKYIVISNDIILQKIKHDKFSIIEKLK 258
WP_055275176 175 NEQPVVGVLVMDNYDEVFHNLNEQEKSEFYGKIISIIMQWADQHKIYIRTTASDRFVLMMPYEVLQQLRETKFTIIDKVR 254
WP_083428280 197 EEQQVLAVIVLDNYDEVRATMHEADRPLAFAKIDGLINRFAADYDAPIIKYESDRYLLVLTKAALDRMKKEKFRLLEQLK 276
WP_083427735 184 QDALAVMVVFVDNLDEAKTGGDEALRTKISSTVDTTIVDYFTSHNSIVRKYDNDKYLVIADRDSFNKIKAKKFNILDTIR 263
WP_072515124 186 EQKPVVLSIHLDNYDDLRTNTAEADRPMLFAEIDRKLNAFANTYEALLVKYETDRYLVVMDALSFASVERDRFPVMEEVR 265
WP_011412290 293 NISHK-YQLKVTLSMGIACWNLSYEKLATYSQNAIELAQKRGGDQVVVN--IENeKIKYFGAKIASLSKQSKVHARINAQ 369
WP_012242153 264 DISTN-YGIRVTLSIGIASWDLEYDELSDYAQNAIELAEKRGGDQAVVN--IQNqKIAYFGAKLESITRSSRTNARLAAQ 340
WP_015777490 262 NIEKG-NTLPPTLSIGVGIAGANPTDIYSDSREAVDIALSRGGDQAVVK--LED-NYEYFGGKTRAIEKTSKVRSRVISQ 337
WP_012358749 274 KISHK-YQLKVTLSMGIACWNVSYDKLAIYSQNAIELAQKRGGDQAVVN--IENeKIQYFGAKIATLSKQSKVSVRVNTQ 350
WP_038467654 255 EISRE-NDLVVTLSAGIACSNIKLNELGDIAQDALDLALSRGGDQVVVN--IEGnDLMYFGGNTNTAEKRTRITTRTNTQ 331
WP_041953392 259 AIEIS-GNIKPTLSIGVGLGGKNPFEKYKEAQTALDMALGRGGAQIVFK--NGE-DLDFYGGKNNKGVERNKVKARVISQ 334
WP_055275176 255 EAAKE-KDIMLTISIGLATGYDSFSELGQRANYMLDLALSRGGDQVAIKiaSDD-KFLFYGGKTNPVEKRNRVRARVNAQ 332
WP_083428280 277 TEMEGlIAIRPTASIGVGYGEDTPAQKMLEARSALDVALARGGDQVVLK--SGE-QLDYFGGKNQATQRMTKVKARVMSN 353
WP_083427735 264 ELEFE-NTIPLTLSIGVCDLGENPNEKFVKARSAIDIALGRGGDQAVCV--GEN-GYEYFGGKTKAVQKHTKVKARVIGY 339
WP_072515124 266 RIRMG-NDIDPTLSLGVAYGDRTPADLLTDARAAIDIALSRGGSQAVMK--EGD-NLRYFGGKNQATERHTSVRARVISH 341
WP_011412290 370 NLVDILKKNPHCFIMGHTHTDLDALGSVIAFYKIAATihPENNNYIILDeeKLDKSLIPVYHQLIkTE-SKKTLNIITTQ 448
WP_012242153 341 MLGDTLNKADQIYIMGHDQTDLDSFGAMIGALKMSLTt-PDIAAYLIVDmeKLDPTVTDVYNYLLsMN-HLVTKHVITTQ 418
WP_015777490 338 ALRRMIQSSPDIYIMGHNNPDMDSFGSSLGVYEGTFD--MGKEVYIVLN--EVTRPIENMYDRVT-TElDELKGNILTES 412
WP_012358749 351 NLVDIIKKYPGFYIMGHNYTDLDSLGSMIAFYKIVLSlkPDCPNYIILDkeKLDKSLLPVYHQLIqQT-TKPLVEIITTE 429
WP_038467654 332 KLERLFEECKHVFIIPHIHPDTDAFGAALGILKLAQA--YGKDTRIVLDkdNLDKTVIKILNMIE-YEyVTLLDYFISPA 408
WP_041953392 335 ALENIIRESSEVFVMGHKNPDMDCFGAALGVMAICKE--LKKDCYMVLE--DVPVTIRNIYDRVRvGE-PDYVDMMIPPE 409
WP_055275176 333 AYERLVRDSERVIIMGHRYPDVDAIGASIGLLRMGIA--SKKEAYIVLKqeELDKTAKNFVDEIL-KD-EKLKKYFISSE 408
WP_083428280 354 TMRSFVEEASNVLIMGHQNADMDSLGSCLGMLTFAEQ--AGGDAWIVLD--EVTASIENLYKKVT-DEaPDLAKRIIRPQ 428
WP_083427735 340 ALKELIDQVENIYVSGHKNPDMDAIGSAVGIMAIVQL--RGKNARLILD--DDTEAVTSIMDLMK-AEsKAMYDSIISPD 414
WP_072515124 342 AVSKMVEEASEVFIMGHTNPDMDSYGACLGMLAFVQK--KETRGYIVLD--GISPAIEHLYKKSL-KElPMLSEMLKDPS 416
WP_011412290 449 QASKMIKDNSLIAVLDTQTKDMLNSPELLSLTPNIVVVDHHRATEEII-PSIFSYVESSASSTVELLVEVMGFLEKEVHI 527
WP_012242153 419 EALARKTKDTLLMILDTQNPQIVHSKELLDLKLKTAVIDHHRGNEASI-KGDFSFIDPGASSTVELMMELFSFFPVEIQL 497
WP_015777490 413 EALSKISPQSLIIVTDNHRKNSTEAPALLDKSDNIFIIDHHRRGKDYIeNATISYIEPYASSASELVTEILSYLDEDFKA 492
WP_012358749 430 KAAKMIDENDVIVVVDTQIKDTLNSPELLGLTNNVIVIDHHRATEEVV-PSIFSYVDPSASSTVELLVEIMGFLTEEIKI 508
WP_038467654 409 KALDSIGRDDLLILVDHHSYNQTIEQKLITKTEKLVIIDHHRKLSDAIpKALISHIEPYASSSVELITEMIDLTTNAVEI 488
WP_041953392 410 KAYDICRDTSSVILVDNSRTLSTEAPYLLDVTSKIVVIDHHRIGKDFVeNPMLTYLEPYASSACELVTEIIYYMFEKIDL 489
WP_055275176 409 AAIELMTKNTLLVVADTQDPKMVIEPALLPRAKKVAVFDHHRRGVDVI-DSVLSFAEPYASSTVELVVDMFDYYSQKIKM 487
WP_083428280 429 RALELRNAQSLIVVLDNHRHDATAEPKLLDEGNRVIIIDHHRRGAGYIqGAEIAYIEPYASSTSEMVTELISYQDSDMTL 508
WP_083427735 415 EALRSFKKGDLLILTDHHKPSLSPSKELSEKADNIVIIDHHRRSDEFIdNPALVYLEPHASSASELVAEILQYMIDDKKL 494
WP_072515124 417 QAVELYKPSSLVIVVDNHRFHSTACPELVEKAEKVIIIDHHRRGRDFIqKATISYIEPSASSASEMITEMLGYLDEKIKL 496
WP_011412290 528 TAFEASIMYAGILIDTNAFIYRTSSRTFEVASKLKDLGADAIEVKSWLRKDFDKVLEINKLISEMEIfMDRFAIIQS-SE 606
WP_012242153 498 DAPEASVMYGGIILDTNTFTYRTNARTFDVASKLKDYGADTMMVKTWLRSDLNRIIKQNELLGKVEIfLDRFAIVKT-ED 576
WP_015777490 493 RTPIAESLLAGITVDTKNFVYQTGVRTFEAASILKRWGADSVYIKRMFKDDFEIVKYKSEVIADSFIvNDFIAIAHFkRD 572
WP_012358749 509 APFEASVMYAGILIDTNAFIYRTSSRTFEVILKLKDFGADGIEVKSWLRKTRDNVDSTNALISKMEIfMGRFAIIKS-DK 587
WP_038467654 489 NSFEATVMLSGIIVDTNNFMYRTGSRTFEASAILRKYGADTFKVKTILREGLEEIQLKSQLLSLAEViHRRFSVVIIpRD 568
WP_041953392 490 DKLIAESLLAGIVVDTKNFYYQTGVRTFEMASYLKRFGADSIAVKQLFKDNFNTIKLKSNVLSNAISyRNYICIGVFpEE 569
WP_055275176 488 TPLEASIMLAGIIVDTRRFSYHTGRRTYETAAILKQKGAEEKLVQQLLRTPLENYYSKAHLIERAEIfKDEFIIACAdDE 567
WP_083428280 509 PKVVAEALLAGITVDTKNFFYQTGTRTFESAAYLKRKGADSVVIKELFKDDFDLMRYRSEILVGAIHfTPDIMIGRFpHD 588
WP_083427735 495 SHFESSALMAGIMLDTKNFTTQTGLRTFEAAGLLTRMGADPEEVKLLFRDDFKTFVNKAKAVESAEIyKDYFAISMTkNE 574
WP_072515124 497 PSVVVEGLLAGITVDTKNFFYQTGARTFDAAAFLKRHGADSIVVKQLFKDDADLVRYRSEVIAQAEEfEHHTIIGRFdRN 576
WP_011412290 607 IYEnRSFLAQVAESVLNIQNVDAAFMIAkIADNKIAISARSYNEINVQTIMEQMEGGGHLNSAATQLEGTNIKTVTDTLK 686
WP_012242153 577 VFNdRTFIAQLSESLLEIKNVDASFTIVnFSDGTVGISARSFGAINVQLLMEEMGGGGHLSSAATQIKDVSVNDAYLQLK 656
WP_015777490 573 IDGsTLIASQAADDLLNIKGVKASFVLT-ISNNKIHISGRSLGDISVQLILERIGGGGHLTAAATQL-DMTMENAEDMLR 650
WP_012358749 588 IYDnRSFLAQVAEDALNISGIDAAFMVAkISNNRIAISARSYNQVNVQTIMEQMEGGGHFNSAATQITGNDIQIVIQNLK 667
WP_038467654 569 LDVsRNLLAKVADDLLEIEDTIGSFAIGyLDDETIGISARSLEGFNVQVIMEKFNGGGHLNNAGAQVLTNDIKQVRLDLI 648
WP_041953392 570 IEEsMLIAAQAADELLGVLDIECSFVLT-IVSGQIHISGRSLGKISVQLILEKLGGGGHYTSAGARL-DCSMEEAIEKLK 647
WP_055275176 568 MVLeKVQIAQTADELLNVQNIKASFVISrIDEQYIGISARSLGDVNVQVLMEQLGGGGHLNNAATQMRSSSTQDAVLQLK 647
WP_083428280 589 MEGsTLIASQAADDLLGIRGIQASFVLT-LAKKRVHISARSLGDISVQLIMEKLGGGGHLTSAATQL-NATLDEAQKQLE 666
WP_083427735 575 GNEaILTAAQASDDLLKIEGVKASFVMA-KIDNMVHISARSMGQVSVQLIMEALGGGGHIAQAGARVEG-TIDEVKEKIK 652
WP_072515124 577 LEGsTLIASQAADDLLNIRGIDASFVLT-RVNGQIHISARSLGEVSVQIIMEKLGGGGHLTASATQL-ACPMDEAEEQLK 654
WP_011412290 687 HFLKLEYE--KGEK 698
WP_012242153 657 HILELEYG--GDNT 668
WP_015777490 651 KAIKEYLR--EEEE 662
WP_012358749 668 RLLKLELEyeKGDa 681
WP_038467654 649 NYLNETVQ--EEKk 660
WP_041953392 648 KAIDEYLL--EEGI 659
WP_055275176 648 EVIVKELE--ESGE 659
WP_083428280 667 EAITAYLK--EEKD 678
WP_083427735 653 DAIDDYIK--EEKD 664
WP_072515124 655 EAIRAYFK--EEE- 665
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