Conserved Protein Domain Family
hypD
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TIGR00075: hypD 
hydrogenase expression/formation protein HypD
HypD is involved in the hyp operon which is needed for the activity of the three hydrogenase isoenzymes in Escherichia coli. HypD is one of the genes needed for formation of these enzymes. This protein has been found in gram-negative and gram-positive bacteria and Archaea. [Protein fate, Protein modification and repair]
Links
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Statistics
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PSSM-Id: 272892
Aligned: 6 rows
Threshold Bit Score: 609.08
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P24192         1 M---RFVDEYRapeqv----mqlieHLRERASHLsytaERPlRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCV 73  Escherichia col...
Q58400         1 MiniNDRALIKka----------idKINKLAEKI----DKL-KIMHVCGSHEHTICKYGIRDVLPENITVVPGPGCPVCV 65  Methanocaldococ...
BAM50321       7 vlamKYVDEYRdaqav----ahyrqAIAREIT-------KPwTLMEICGGQTHSIVKYGLDALLPKNLTLIHGPGCPVCV 75  Bacillus subtil...
WP_000109824   1 MsvdHLISPFRdkrtl----lalsnAIKKLAFKL----EKKlVIMEVCGGHTHSIMKYGLLDLMPNNLEFVHGPGCPVCV 72  Helicobacter py...
WP_010878867   1 MrrrQKRLGSCwrelqmkpvirlseKIRELSKEF----ESv-KIMHLCGTHEDTITKYNLRSLLPENISLLSGPGCPVCI 75  Archaeoglobus f...
WP_010876696   1 MknlSRElv---------------sRIQEIS--------RPvKIMHVCGSHEHTIMQHGVRSLLPEEVEVVAGPGCPVCC 57  Methanothermoba...

P24192        74 LPMGRIDTCVEIAsHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPT 153 Escherichia col...
Q58400        66 TTQKEIDTAIYLA-DNGYVITTLGDMYRVPGSEKSLMEKQSEGCDVRIVYSISEAVKMAKKERDKKFVFVAIGFETTAPT 144 Methanocaldococ...
BAM50321      76 TPMELIDQALWLAkQPEIIFCSFGDMLRVPGSGADLLSIKAQGGDVRIVYSPLDCLAIARENPNREVVFFGVGFETTAPA 155 Bacillus subtil...
WP_000109824  73 MPRARLDEAYELAtIKDSIVLSLGDMMRVPGSYGSLIQAREKGLDARFLYSPMQALEIAKENPTKKVIYIAIGFETTTPM 152 Helicobacter py...
WP_010878867  76 TPDEDIQMVMHLLeKENITLATFGDMARVPFQGKSLFTLRAEGYDIRIVYSIFDSLKLAESS-DRPVVHFAIGFETTMPS 154 Archaeoglobus f...
WP_010876696  58 VPAREIDECIELA-RQGVTITTFGDMLRVPGSRGSLADARADGADVRIVYGVGNAVEIARKL-DREVVFMAAGFETTAPT 135 Methanothermoba...

P24192       154 TAITLQQAKARDVQNFYFFCQHITLIPTLRSLLEQPDNgIDAFLAPGHVSMVIGTDAYNFIASDFHRPLVVAGFEPLDLL 233 Escherichia col...
Q58400       145 TGAELISLKNKDVNNFFILNCHRQTPPVMEFLLNEGVY-LDAFICPGHVSTITGLKPYYGLCEKYKAPMVVAGFEPIDVL 223 Methanocaldococ...
BAM50321     156 TAMTLHQARAQGISNFSLLCAHVLVPPAMEALLGNPNSlVQGFLAAGHVCTVTGERAYQHIAEKYQVPIVITGFEPVDIM 235 Bacillus subtil...
WP_000109824 153 SASVLWSAKKEKINNLFFHINHILVPPSVSAILKDPACqINALLAPSHVSVISGAQIYAPLVDRFKIPIIVSGFEPVDIL 232 Helicobacter py...
WP_010878867 155 TAIALLDEK----ENFYVFSAHRFFIPAVHALCENTTV--DAFINPGHVSTIIGVKPYREILKKYGIPQVIAGFEPEDVM 228 Archaeoglobus f...
WP_010876696 136 TASEILSGPPE---NFSVLSCHRLIPPALRFLIESGEVnLNALIEPGHVSTIIGMKPYEPFSRDYNIPQVIAGFNPLDIL 212 Methanothermoba...

P24192       234 QGVVMLVQQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCvNGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQ 313 Escherichia col...
Q58400       224 MAIIMILKQVISGEAKVENEYIRAVKPEGNVLAQKIINEVFE-SIDVPWRGFPVVKNGGFGLREKYKKFDIYEHEDIPEI 302 Methanocaldococ...
BAM50321     236 QGIFACVRQLESGQFTCNNQYRRSVQPQGNAHAQKIIDQVFE-PVDRHWRGLGLIPASGLGLRPAFAPWDAAVKFANLLQ 314 Bacillus subtil...
WP_000109824 233 ESVLMLIKQALNKEAKLEIQYKRAVSFEGNVKAQELVNACMEvRENFEWRGLGNIKRSALKLKEAFASYDAEEVFKEYLS 312 Helicobacter py...
WP_010878867 229 LAIYLLLEAMSDGRREVINEYSRAVKEEGNVRALEAMDRVFR-KEDWSWRGLGVVKGSGGALAKRFEQFDARKVFEDAFA 307 Archaeoglobus f...
WP_010876696 213 MAVYMILRQIDRGEAKVENEYKRAVKPEGNLKAQKVMDEVFK-VTEREWRGFPVIPESVYEIRDEFSEFNAREKFDIEVE 291 Methanothermoba...

P24192       314 QVCDdPrAR-----CGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQ 369 Escherichia coli K-12
Q58400       303 KEKI-P-KGc---iCDKILRGEKLPTDCPLFGTVCTPLNPVGSCMVSDEGTCRIFYKYRRI 358 Methanocaldococcus jannaschii DSM ...
BAM50321     315 TMAPtMgETvc--iSGEILQGQRKPSDCPAFGTICTPEQPLGAPMVSSEGACAAYYRYRQQ 373 Bacillus subtilis BEST7613
WP_000109824 313 HKTSkEnKAc---kCGEILKGIAKPLDCSLFATTCTPQNPIGSCMVSSEGACAAYYRYKRV 370 Helicobacter pylori
WP_010878867 308 DFQPvEdKSkrlcrCGDVLKGIATPKDCPLFMKACNPRNPVGACMVSVEGTCNIWATSGTS 368 Archaeoglobus fulgidus
WP_010876696 292 DTVDtP-AGc---iCGAVLRGVARPEECKLFKNECTPTSPIGACMVSREGTCNIAYRYSSF 348 Methanothermobacter thermautotroph...
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