3CSK


Conserved Protein Domain Family
Peptidase_M49

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pfam03571: Peptidase_M49 
Peptidase family M49
Statistics
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PSSM-Id: 460976
Aligned: 104 rows
Threshold Bit Score: 643.768
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3CSK_A            154 INELIDIGIYHVEEKAALLGFPSQGy--TSAYYLGLp----VTPEDMALLKeQLFAEL--AILPENTRINK-VGENS--- 221 baker's yeast
Q0CEW8             84 LCKQCGPAICASTP--SHLGYPSRIa--QSSYYVGQv---qITREEIDQLA-PLLVKA--NIRPRHSRVCKdLDETGah- 152 Aspergillu...
XP_011106984      134 IYERISDAMYSTMP--LCLGYPSETgqaQSRYYISSgdaepFTKDEISSIS-QILQDR--GIHQENTEFVKkLSRADn-- 206
EMD90822          129 LYEKISNAIKAMPP--YGLGFPSHTa--QSMYYPGDs---iITRDEISEVS-RVLEKH--SIFPENTRIQKvSNTKAq-- 196
KLU89104          128 LYEAISDAIRMRPP--FSLGYPGESt--QSSYYLGPa----ITEQEIAAVT-RVLEQN--SIFPENTRLRKaPNGKD--- 193
jgi:THITE_2147951 129 LYDEISPAISAIPP--FSLGFPSATt--QSSYYLGA-----LTPQEITSVD-RLLEQQ--SIFPENTRLQKpADTTTggt 196
XP_001324003      133 LLDECIEDIYDVSGPKSQLGFNPDG---CTVYYQPDd----FTQSEAEGID-QVLKAA--GVRIENTAIIR-HADK---- 197
Q22KE9            144 VWENTNYELYAYHNPYQIIEFINNQg--HTSYYSSN-----ISQQNAEQIS-KFMEQKdiNLSPLNTRLLK-HSETE--- 211 Tetrahymen...
A0DXU3            136 VWENVRKYIYNYDKPYGLIDLQEKNg--SNSYYSNN-----LKGELLEAVD-KFLIAQ--GVSELNTRVVK--VEEE--- 200 Paramecium...
A0E5G8            143 IWNLIEKYIYSYEKPYGLLDLLEKGg--SNSYYSPN-----LSKEFIEELD-QFLHKQ--NLSELNTRVIL--KEDR--- 207 Paramecium...
3CSK_A            222 -----FQIWV--ASenvknqiteTYPSGQITLS-NAVt-K---VEFIFGDHSREMRLVASYLKEAQKFAANDTQKAMLQE 289 baker's yeast
Q0CEW8            153 ---vvFNILQ--ASvd-----ksDSPEPLGTLSnGAP------VTSTKGDHSLELDKINTHLRAARQVTDHPLRVEFLSY 216 Aspergillu...
XP_011106984      207 ----gYSFTVfqASid-----lpEAPILLSSTMrEGKefT---VVLLKANHRKQLEKINDELTAALAYCANDRQKLVLQK 274
EMD90822          197 ----iFKVLR--ASve-----hdIQPSILEIPSlGAT------IEIKCGDHSEDLARICNSLSEAKKYAANKKQEDFLSQ 259
KLU89104          194 -----YEVLV--GSvv-----rdDRGASGTTKTlPLGddQkgiVTIVRGDHSADLERICTELSSAVEHAANDLQRQFLAA 261
jgi:THITE_2147951 197 tstptINILV--ASaq------pTPPPTRLPSTiPTTkaN---IHLRKGDHSGPLRAICTELSFASAHAATEAQRAVLRG 265
XP_001324003      198 -----YEVSV--ASi-------eVDEKGQKVGTyNGK--D---VYVTKGRSSEALKKVVKHLNEALKNVANDTQAEMIKC 258
Q22KE9            212 -----YEILV--ASi-------tKDLQPEKDYEfEGL--K---IKITYGDFKPFLASLNGYLEKCIKHAENDHQVEMIKS 272 Tetrahymen...
A0DXU3            201 -----IHVLV--AS---------VNKGEKELGEvHNH--K---VKLVYGDFSPFLNSVVTHLTQALQYAANDNQKNMIQA 259 Paramecium...
A0E5G8            208 -----VELLV--ASs--------ERSDVVELGEvKGK--K---VFAIYGDFKSFLNGVATNLREAQKYAANETQVKMLEE 267 Paramecium...
3CSK_A            290 YINHFVTGSSQAHKEAQKLWVKDISPVIETNIGFIETYREPSGIIGEFESLVAIQNKERTAKFSSLVNNAEE--FISLLP 367 baker's yeast
Q0CEW8            217 YERYFQTGDMGLFDNAQRVWMKDKQPRVETFFGFNHKYRDPAGARAEFQGFVGLLDSDGSRELNALQQDAQK--YIATLP 294 Aspergillu...
XP_011106984      275 LIESFKTGDMEAYKESQRHWVKDIQPAVENIFGFVEPYRDPAGVRAEFEGLVGLVDKDETRTLTALAENSAR--FIRLLP 352
EMD90822          260 YIESFRTGDLEAYRNSQRTWITDKSPRVENIFGFVEPYRDPYGIRAEFEGLVAIMDLEETSKLTMLVESSGI--FIKRLP 337
KLU89104          262 YIESFRTGNLEMYRESQRLWVRDRAPRVENIMGFVEPYRDPHGVRAEFEGLVAIADDEETALLTKLVQNSAK--FIRRLP 339
jgi:THITE_2147951 266 YLASFETGDLHAYRAAQRAWVRDITPRVESVLGFVEPYRDPAGVRGEFEGIVGFVDAEGEKGLARLAVGDGGrwLVRRLP 345
XP_001324003      259 LIEHFTTGSVAAHVKYSEHWVKDVDPVVETHTGFIENYRDPKGCRCEFEGLVSCVDKNESVALHNFVDSSAT--ILKLLP 336
Q22KE9            273 YLKHFENGSIDEHKNSQRHWIKDKGPIIETNIGFIESYLDPLKVRAEFEGFVSVVNKEESKKLEELVSKAEG--IISHLP 350 Tetrahymen...
A0DXU3            260 YIEHFQTGDVELHKSSQRHWIKDKGPVIETNIGFIETYLDPLKVRAEWEGFVAVVNKEESALLNELVNKAED--IIKYLP 337 Paramecium...
A0E5G8            268 YIKHFQSGDIEQHKESQKHWIQDKGPIIETNIGFIETYLDPMKVRAEYEGFVSIVNQEESKLLGNLVEKAED--IIKDLP 345 Paramecium...
3CSK_A            368 WS------KD--------YEKPIFNPPDFTSLEVLTFTGSGIPAGINIPNYDDVRLKIGFKNVSLGNIL-------SAAA 426 baker's yeast
Q0CEW8            295 WVd----gLQgqggangpFEMDEFQAPDFNAVYALAYAATNIFTGLSMPAFCDNWIDYAWKNLMVKTRD-------QALR 363 Aspergillu...
XP_011106984      353 WTk-----GFtdndgkgpFEKELFEAPDFTSLHTLAYCSSIIFPGINLPNFNDIRQETGFKNVMIANSMnppgrdsGADH 427
EMD90822          338 WA------GGdendgkgvFEKALFEPPDFSSIHSLAYCSSIIFPGINLPNYNDIRDELGFKNVIIANRM-------CAEG 404
KLU89104          340 WA-------SeendgkgpFEKSLFEPPDFSSIHALAYCSSIIFPGINLPNYNDIRQEVGFKNVIVANRM-------AADS 405
jgi:THITE_2147951 346 WViasggeGGeggggmgpFEKDGVEANGLASVHALAYCSSIIFPGINLPNYNDIRQEVGFKNIIFANRM-------RVES 418
XP_001324003      337 YP------KE--------YERATFNPPSYNALNILQMTSTGYPIGINIPNYDEIRLNVGFKNVTLSNVL-------SSVA 395
Q22KE9            351 WP------KE--------FEVEKFTKPDFTSLEVLTFASSGIPIGINIPNYDDIRQTEGFKNVNLGNVY-------STPK 409 Tetrahymen...
A0DXU3            338 WP------KE--------FEVDVYKRPDFTSLEVLAFASSGTPLGINIPNYDDIRQTEGFKNVNLGNTI-------GKLS 396 Paramecium...
A0E5G8            346 WP------KE--------FEIEKFSRPDFTSLEILAFACSGTPVGINIPNYDDIRQNLGFKNVNLGNVY-------GKPN 404 Paramecium...
3CSK_A            427 k--sSSKhpPSFISQEDRPIFEKYQSDSFEVQVDIHELLGHGSGKLL-TEFTDG-FNFDKENPPl-GLDGKPV-STYYKV 500 baker's yeast
Q0CEW8            364 vgelSQGepAWFIAEAERTTYLQHVDQSVTFKVALHELFGHGTGKLL-SQLGPDeYNFDIKNPPmnPLTGTPI-TSWYSQ 441 Aspergillu...
XP_011106984      428 s--lPQE--AIRVDPSLESEYIKHYQATFYLWVVFHELLGHGTGKLL-TENSDGsFNFDKENPPinPVDGKPV-SSWYKP 501
EMD90822          405 k--kARG--SPFIDPAELDSFQKANYPAYYWWVVLHELFGHGTGRMM-VEESEGkFNFDIHNPPvsPLTGKPI-TTWYKL 478
KLU89104          406 q---AMQ--YPFINPSEVEQFKKHKFPAYYWWVVLHELLGHGTGRMM-VEKEYGqYNFDVNNRPinPLTGKPI-SGWYKL 478
jgi:THITE_2147951 419 q---AKQ--YPFIDPAEAETFAKHKFPAYYWWVVLHEILGHGTGRML-VESAEGkYNFDINNPPinPLTGEPI-TSWYKP 491
XP_001324003      396 v--qKSV--LDILDPSIRDVFSEYCEQIESLAVAAHELYGHGSGRLLkQKDIEGgKVDDLLNP------GRKVeTCWPED 465
Q22KE9            410 ----KEN--VLFANEATAELYCKYFKDSLFVIVALHELLGHGTGKLF-QKKEDDtLNFDQEHLLh-PILNTKI-DTYYDK 480 Tetrahymen...
A0DXU3            397 ----KDA--IKFLDEADQEIFYKYQSEAVFLVVALHELIGHGAGKVF-MKDKDGnLNFNLENTIn-PLTNQKV-DSYYNH 467 Paramecium...
A0E5G8            405 ----RDS--VRFLQGTDIDLFINYYKESLFVVVALHELIGHGSGKIF-MEDKDGkLNF--ENVTn-PFTNEKV-TTFYKP 473 Paramecium...
3CSK_A            501 GETWGSKFGQLAGPFEECRAEVIAMFLLTNKKILDIFGFHD--VESQDKVIYAGYLQMARAGLLALEYWNPKT--G---- 572 baker's yeast
Q0CEW8            442 EQRTSSVFGEMDMSLEECRAEAIAAYLAFDKGILSTMGYSDssDITADDc--------------RFSIWQEQKerKaavi 507 Aspergillu...
XP_011106984      502 GETWTGLFGDIATSVDECRCEVVGALLVRFPGVVGFFGYTDetHTTPKDMELNIYLQLGCAGLRALNNYIVED--K---- 575
EMD90822          479 GQTWTGQFGDLATTVDECRAELVGAYLMDDVELLELLGYDEnsEITAADLTYNIYLQLGTDGLRGLANFNVEH--K---- 552
KLU89104          479 GQTWTGQFADLATTVDECRAELVGAYLMDDSELLELLGFTAtsEIRAEDLTYNLYQQLGMDGLRGLSNFNTDS--G---- 552
jgi:THITE_2147951 492 GQTWTGQFGDLATTVDECRAELVGAYLMDDPEVLALLGFTEdlEIRAEDLTYNLYQQLGVDGLRGLANFNVDS--G---- 565
XP_001324003      466 GTSFDQMFGACSSAYEECRAETTAVYLTFFDEVLDIFNVAKd-KSVRRNFLFVTIVKMLVAGLRSMWCYSAEA--K---- 538
Q22KE9            481 NETWHSKFGDISSSYEECRADSVAIYLSCFQESLDILIPEYs-KEEQSDLVYIAWYEIVVSSIKGLEYYNPEL--K---- 553 Tetrahymen...
A0DXU3            468 GEQWHSKFGEFSGAMEECKADATALYLSTYDDVVKLLLPNQs-EEERRNTVFAGWLFVVHRAVQGLEFYNPEQ--K---- 540 Paramecium...
A0E5G8            474 NEHWHAKFGELSGAYEECRADSVALYLSTYDDVVQILVPGKt-KEERDEIVKAAWLDIIMGALKGLQYYSAEQ--S---- 546 Paramecium...
3CSK_A            573 KWGQPHMQARFSIMKTFMkhSTDkNFLKLEMNStNd--dFAIKLDKSLIKTAGHECVKDYLKHLHVYKCSGDVEQGSKYF 650 baker's yeast
Q0CEW8            508 KWTSAHDRARFGILRTLM--AAD-NFMRVVYEEdPp--lLTVHIDRARLESIARPAISTLMTKLHVWRCSADGPAATDFY 582 Aspergillu...
XP_011106984      576 KWGQAHSRAHFAIMRILL--QAGdDFLVIKENAqEq--tLTVYVDQTKTKTHGIPALSDFLLKLHMFRSTANVKECREYY 651
EMD90822          553 KWGQAHSRAHFAILKCLL--TDSdGCVTVEHNAqSk--sLIVRVDRSKIISHGKPALGRMLLQLHLFRCTGDVQSCREYY 628
KLU89104          553 RWGQAHSRAHFSILKCLL--LDGgGVLSIVHDKaNn--sLTVRVDRSKIATHGKRALGRMLLHLHMYRCTADVEACRAYY 628
jgi:THITE_2147951 566 KWGQAHSRAHFAILQCLL--RNGdGVITVTHDKaAr--sLTVRVDRSKIRTHGKPALGAMLLRLHMYRCTADVAACRTYY 641
XP_001324003      539 RWTQAHSAARFAILRACI--MWGrGAAEVKKLPdGg---YQLFVDINKLDG-IQDAITRLLKHLTYYKSTCLPGPGADFF 612
Q22KE9            554 KWGQAHTAAAYAITKVLIe-AGQ-GLVTIEKTEkEgkpyVYIHLDKSKIWTVGKEAMRKFLIGLQVYKSTGDSVRGIEFF 631 Tetrahymen...
A0DXU3            541 KWGQAHVLARNVILQSLI--REDpDIIKITETQlNgkpyIHFKFDQSKLYTTGKKAISNLILHLQVFKSIGAGNQGVEFF 618 Paramecium...
A0E5G8            547 KWGQPHILASYVILQSII--QKDpSFVQFVHSEfNnkpyFTVQVDYSKIWTVGKEAIADLLKGLQVYKSVADGENGMKFF 624 Paramecium...
3CSK_A            651 IDRSTVTPDLASLRDIV---LSKRLPRRQFIQSNSYIDd-------NNK--VT-LKEYDETPQGMLQSFLDRE 710 baker's yeast
Q0CEW8            583 GQLTEVDGVWLRIREVVvdrVKNQAPR-LFVQANTILEegtidsdtGPR--VR-VVEYDTTVEGVIQSWCERE 651 Aspergillus terre...
XP_011106984      652 EELTEPSEQFLRWRHII---IANAAPPKLFVQDNTIINs-------DGE--VV-LLGYSPTLEDLVDSWVDRN 711
EMD90822          629 EELSSVHAEHLAWREIV---LAKQEPRWVFVQANTFLR--------GEE--VV-LQEYPATVKGVIQSWAERE 687
KLU89104          629 EDLSRVDGEYLEWRETV---LANKPPPMVFVQANTLLGd-------DGS--VS-LKEYEPTVEGIIQSWAERK 688
jgi:THITE_2147951 642 EDLSRVDEEHLAWREAV---LANKPPPLVFVQANTFLE--------GDR--VV-LKEYEPTVEGVIQSWAERM 700
XP_001324003      613 AAMTAIDDRWMAVKKFI-----DAQPRKRPAYCGGVVRge----agNYK--IEsVVQDKATPLDVALTFVENI 674
Q22KE9            632 NKYLAVDDEMLEYRKIA---LDNKKPRKLSLQSHVKLV--------GNEenVE-LVNFESTFEGLIKSFTHHY 692 Tetrahymena therm...
A0DXU3            619 SNLAAVSDKFLNYRNIV---IQNKFPRRLEIQPNLVLE--------EGQ--VN-LKEYEPTLAGIIESQVEHH 677 Paramecium tetrau...
A0E5G8            625 NKFTQVDQKFLQLREIV---LAHKQPRKIELQPDVKLN--------NGQ--VE-LVVFPESHEGVIQSHIFHY 683 Paramecium tetrau...
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