7KB1,4KAM


Conserved Protein Domain Family
MET17

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COG2873: MET17 
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Statistics
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PSSM-Id: 442120
Aligned: 617 rows
Threshold Bit Score: 486.844
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7KB1_A         1 MD--------------W--------KKYGYNTRALHAGYEPpEQATGSRAVPIYQTTSYVFRDSDHAARLFAL------- 51 
WP_015802766  21 AR--------------A--------RRWSFETRQVHAGAAP-DPATGARATPIYQTTSFTFADSAHAADVCAL------- 70 
WP_013584636   1 MA--------------EaaaphaewEGFGFQTRQVHAGEVE-DLTHGSRVTPVHLSAAYRFASFQEATDRFAG------- 58 
WP_015101169   1 M------------------------SGWSFDTRQVHAGARP-DPATGARATPIYQTTSFAFEDANHAAEVFAL------- 48 
WP_054292128   1 M------------------------TNWSFETRQIHAGAKP-DRATGARATPIYQTTSFVFDDGDHAAAAFAL------- 48 
WP_082717002   1 MPhtelpe--nrqaeqApaaplfdwEGLGFDTRQVHAGDYA-DQNRGARVPPITLSAGYVFDSFDDGVARFAG------- 70 
WP_066596363   1 MTdtcpplsenpavtpDalgpeydwAGYAFDTRQVHAGEYD-DRTSGARIPPINMTAGYRFNSFQDARARFAG------- 72 
WP_085021423   1 ----------------------------------MHAGEQP-EPGHGSRVTPIHLANAFRFESFDQTHGRFAG------- 38 
WP_120788232   1 Mp-------------------------LDFETRQIHAGAVI-DAHAQARVTPIYQTAGYVFDDFDDGEARFAG------- 47 
WP_130109824   1 MT--------------GaaqpvydwDGFGFETRQVHAGEYP-DKNHGLRVPPIALSAGYLFEDFDDQVSRFDGsihwkae 65 
7KB1_A        52 -------------EEP-GFIYTRIGNPTVSVLEERIAALEEGVGALAVASGQAAITYAILNIAGPGDEIVSGSALYGGTY 117
WP_015802766  71 -------------RDLdSHAYSRIGNPTTAVAEARLADLEGGVAAVALASGQAAITLALLNLARTGDHVVASAALYGGTR 137
WP_013584636  59 -------------ADL-GHLYSRNLNPTNQVAERRLASLEGGSGAIVVGSGQAAITTALLALAGSGEHILSTASIYSGTR 124
WP_015101169  49 -------------RDLeSHAYTRLSNPTTLVVEERIADLEGGVAAVAVASGQAATTLALLNIARAGDHVVSSAALYGGTY 115
WP_054292128  49 -------------QDLeTHAYSRLSNPTTAVVEARLADLENGVAAVAVASGQAASALAILNIARAGDHVVSAATLYGGTY 115
WP_082717002  71 -------------ESQ-EPIYSRQGNPTNAVAEQRIASLEGGTAAVVVSSGQAAITAALLALAESGEHIVSTASIYGGTR 136
WP_066596363  73 -------------EAD-GLIYSRQRNPSGNVAERRIASLEGGTEAIVVASGQAAITAALLSIAQHGDHIVSTASIYSGTR 138
WP_085021423  39 -------------TDE-GQLYSRHLNPTNAVAEGRIASLEAGAGAVVVGSGTAAISTTLIALLEAGDRFVSTASIYSGTQ 104
WP_120788232  48 --------------RG-GRAYSRNENPTNYIAGQRIADLEGGVDGIVVASGQAAILVAVSALAGTGDHLLITKSLYEGTN 112
WP_130109824  66 ehpgredpagfspSER-AAIYSRQGNPSNWVAEERLASLEGGVVSVAVSSGQAAISAALFALAQQGDHIVSTASIYGGTR 144
7KB1_A       118 NLFRHTLyKKSGIIVKFV-DETDPKNIEEAITEKTKAVYLETIGNPGLTVPDFEAIAEIAHRHGVPLIVDNTVA-PYIFR 195
WP_015802766 138 VLLAHTF-TELGIGVDFVaDADDPAAWRAAVRPNTRAFFAEVVGNPLGNVLDLRAVADVAHEAGVPLVVDNTVPtPYLCR 216
WP_013584636 125 VLFDRTF-ARMGVTVEYVwDPDDEAEWDALVRPETKAIFTETLPNPKNDIVDIAAVARVAKRYGIPLIVDNTIAtPFLIR 203
WP_015101169 116 NLLAYTF-ADLGITVDFVrDPDDLAAWRAAVRPETKAFYAESVGNPRGNVLDVAAVADVAHQAGVPLVVDNTVPtPYLSR 194
WP_054292128 116 NLFAYTL-RDMGIEVDFVtDPDDLDQWRAALRPTTKAFYAETVGNPLGNVLDITAVAEVAHAAGVPLVVDNTVPtPFLTR 194
WP_082717002 137 ILFGRSF-RRFGVSVDYVwNIDDDAEWEQAIRPETKAIYTETIPNPRNDVVDIARIAEVARRHGIPLVVDNTVAtPYLLR 215
WP_066596363 139 ILFGRSF-ARFGVTVDYVwDEFDDDEWDRVIQPNTKAIFSETIPNPKNDIVDIGRVAAVAKRHGIPFVVDNTIAsPFLIR 217
WP_085021423 105 ILFDRAL-KRLGIGVDYVhDWHDPAEWAAAIGPSTKAVFTETIPNPKNDIVDVELVARIAADAGIPLVVDNTVAtPYLVR 183
WP_120788232 113 EMFRGVL-KRQGIEAEYVpDEASDEEWAARFRPNTKALYTESLTNPLGQVTDLARLARIAHAHGVPLVVDNTVPtPYLER 191
WP_130109824 145 ILFGRSF-KRFGIEFDFVwDADDDAEWERAIRPNTKAIYTETIPNPCNDVTDLRRIAEVAARYNLPLVVDNTVGtPALIR 223
7KB1_A       196 PFEHGADIVVYSATKFIGGHGTSIGGLIVDSGKFDWt-----NGKFPELVE-PDPsYHGVSYVETFK-EAAYIAKCRTQL 268
WP_015802766 217 PLEHGADVVVHSTTKFLAGHGSSVGGAVVDGGRFDYaa---dPDRWPQFTE-PDPgYRGVVFAADFGe-LAYALRLRARL 291
WP_013584636 204 PIEHGAHVVVHSATKFLSGHGANLAGAVVDGGTFDWva---sDRSYPAITE-TPIaTH-ASFVDAFG-PRAFEFSLRFGI 277
WP_015101169 195 PFEHGADIVVHSTTKFLSGHGSGIGGVVVDGGRFDFta---dPARWPQLNE-PDPsSHGLVFGQEFG-DVGYSLRLRTKL 269
WP_054292128 195 PIDHGADIVVHSTTKFLSGHGTGVGGVVVDSGRFDFta---dPARWPQLTQ-PDPsYDGLVFGTQFG-NLGYLLRLRTKL 269
WP_082717002 216 PFEHGADIVVHSSTKFLSGHGAGVSGAIVDGGRFDWaa---tSRRYPLLTD-PPR-PGAGSYLDRFG-PTAYAQYVREAV 289
WP_066596363 218 PFEHGADVVVHSSTKFLSGHGAAISGTIVDGGSFDWaa---aDRPYPLITQ-STGg--LPSIAEKFG-QTAYARATREAV 290
WP_085021423 184 PLELGASIVVHSSTKFLAGHGAGISGAVVDGGTFDWrg---sPRAYPLLTD-PQS-PGAPSFLDRLGpRHAFAGYLRLTA 258
WP_120788232 192 PIEFGADVVIHSTSKWLSGHGSVIGGAVIDGGRFDWv----aSGRFPQLTEaPRPgVG--SFVERFG-TGALGAYLRTVV 264
WP_130109824 224 PFEHGANIVVHSATKFLTGHGAAVGGAIVDGGNFDWeaaeraGRSFPLITR-SSR-PGVASMLDRFG-TGAYARATRESV 300
7KB1_A       269 LRDLGSCMSPFNAFLFILGLETLSLRMKKHCENALKIVEFLKSHPAVSWVNYPIAEGNKTRENALKYLK----------- 337
WP_015802766 292 ARDLGPAASPFNSFLLLQGIETLSLRVERHVANAGVVARWLAGRPEVARVHYAGLPDDPWHAAGQRYLP----------- 360
WP_013584636 278 ANDTGPALSPLNGFLLQQGMETLSVRMRQHLASARTIAEWLETHDAVESVDYAGLPSHPQHALAVRDYG----------- 346
WP_015101169 270 VRDLGPAVSPFNSFLLLQGIETLSLRLDRHVANARAVAEWLADQPQVTEVHYAGLPDSPWHDAAKRYHP----------- 338
WP_054292128 270 VRDLGPAVSPFNSFLLLQGIETLSLRMERHVANASAIAHHLREHAAVEQVHYAGLPGNRWHEAAKQYLP----------- 338
WP_082717002 290 VNDIGPSLSPFNGFLLHQGIETLSLRMDRHVENSLAIARWLTEQPEVVGVDYAGLPENPLHELAQRHYG----------- 358
WP_066596363 291 VNDIGPALSPFNSFLLHQGIETLSLRMERHLSNSLTIAGWLAGHARVESVDYAGLPGNPAYELAQTLYV----------- 359
WP_085021423 259 VNDLGPALSPFTGFLLQQGIETLSLRMERHLENAVAVARWLADQPEVESVDYAGLPGHPDHALAERLYG----------- 327
WP_120788232 265 VLEYGPTVPPTSTFLLLHGIETLSLRMDRHVANAQAVAEFLEGRPELASVLYPGLASSPYKSLADTYLP----------- 333
WP_130109824 301 VNDIGPTLSPLHGFLLHQGMETLSLRMERHVASSQRIAAWLEQQPEVESVDYAGLPSHPLHELALRDYGtapgtsgapgg 380
7KB1_A       338 ----EGYGAIVTFGVKGGKEAGKKFIDSLTLISHLANIGDARTLAIHPASTTHQQLTEEEQLKTGVTPDMIRLSVGIEDV 413
WP_015802766 361 ----LGVGAVVAFELVGGLEAGRRLVDRVRLFSHLANIGDVRSLIIHPASTTHAQLEPAEQVAAGVTAGLVRLSVGLEGV 436
WP_013584636 347 ----GLSGSVFSFTVRGGRDGAERFFDALRLFSRMTNIGDTRSMALHPATTTHLGFTQETRDRLGIGDGLVRLSIGLEDA 422
WP_015101169 339 ----LGVGAIVSFELAGGVAAGRRFVDRVELFSHLANIGDVRSLAIHPASTTHAQLTPDQQAASGVTPGLIRLSVGIEGV 414
WP_054292128 339 ----HGAGAVLAFELAGGVAAGRKFVDSVELFSHLANIGDVRSLVIHPASTTHAQLTPEQQLASGVTPGLVRLSIGLEGV 414
WP_082717002 359 ----GRTGSVFAFTVAGGIEGARAFSDGLSVFSRMTGIGDTRSMVLHPLTTTHASFPAELNARLGITPGMLRLSVGIESL 434
WP_066596363 360 ----GRSGSVFSFTVRGGEAGAGRFLDRLRVISHMTNIGDTRSMALHPATSTHTSFSQDLRDRLGITPGLIRISVGIEDV 435
WP_085021423 328 ----GRTGSVFAFTVAGGLDGARILIDRLQVFSRMTNIGDTRSMAIHPGTTTHLSFDDERRARLGIPPGLIRLSIGIETL 403
WP_120788232 334 ----RGAGSVVSVDL-GSREAARRFIDALELITPMTHIGDVRTLAIHLGTTIHLKLDEQQQADAGITPGLVRLSIGIESA 408
WP_130109824 381 qsgiARTGSVFGVTVRGGIAGARACVDGLRVFSRMTGIGDTRSMVLHPLTSTHGTFAPEITERLGITPGLLRLSVGLESA 460
7KB1_A       414 EDIIADLDQALRKS 427
WP_015802766 437 ADLVADLEQALGDG 450
WP_013584636 423 EDLIADLDQALRAA 436
WP_015101169 415 GDLIADLRRGLADG 428
WP_054292128 415 EDLIADLNRGLHA- 427
WP_082717002 435 DDLLADLRRGLDRV 448
WP_066596363 436 NDLIADLDAALGv- 448
WP_085021423 404 DDLIADLRHGLDAV 417
WP_120788232 409 RDIIADLERGLAAA 422
WP_130109824 461 DDLIRDLRGALDRV 474
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