Conserved Protein Domain Family
WKF

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pfam10180: WKF 
WKF domain
This is the C-terminal conserved region of a family of proteins found from fungi to humans. The domain is named WKF after a conserved sequence motif. This domain has been shown to bind RNA. This domain was previously known as DUF2373.
Statistics
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PSSM-Id: 462982
Aligned: 122 rows
Threshold Bit Score: 65.2297
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002499108         96 YLIEFYLNKVNpknlpdslssltnvrnnysekfnnddqddddnssesevidiWKFSKQKQNWLIKHFFNAEEIPVEYDEL 175
ETN63937            104 YLECWSSQREK-----------------------------------------WKFQKLKQIFIQKYILDENHIDTDMWPV 142
Q5TWS1              153 YLDTWGKNRQE-----------------------------------------WKFSKLKQIYIQEHVFDDSFIGEEAWPI 191 Anophele...
WGS:AAQB:GK12513-PA 228 YLNNWKNSRQD-----------------------------------------WKFNKLRQISIQKLAFDVEKLGSEIWPI 266
XP_002035061        179 YLLKWKESRQD-----------------------------------------WKFNKLRQISIQQTAFDVEKLDEELWPT 217
EDW33172            174 YLLQWKNSRAE-----------------------------------------WKFVKLRQISIQQTAFDEEKLAAEIWDI 212
XP_001984470        144 YLVKWRDCRQD-----------------------------------------WKFVKLRQISIQQNAFNEQKLNADIWAI 182
XP_002047420        145 YLRKWRDSRQD-----------------------------------------WKFEKLRQISIQQTAFDEKKVSADIWPI 183
XP_001708830         46 wMYHWHTDRST-----------------------------------------WTFDKKQQTLLVQAWMDSERMPKDTFAV 84 
XP_003382775         58 YLRQWSTDRDS-----------------------------------------WMFKKKLQFWLIKNIYNKEKIGKADFKI 96 
XP_002499108        176 LLSYFKELKSPaIKDRVTAVCKA 198
ETN63937            143 ALEYLSGTKGA-SRDLLIKNAET 164
Q5TWS1              192 AVEYLSKTQGF-ARDLLTAKAKA 213 Anopheles gambiae str. PEST
WGS:AAQB:GK12513-PA 267 ALEYLASSKGA-AKATIIKLAED 288
XP_002035061        218 ALEYLASSQGA-ARSKISQLAEE 239
EDW33172            213 ALEYLASSQGA-ARAKISKLADE 234
XP_001984470        183 ALEYLAASKGA-SKTTVTKLAQD 204
XP_002047420        184 ALEYLAGSKGA-AKAMISKLAED 205
XP_001708830         85 FCLFAAGSEAEaFKRRLLQEAEv 107
XP_003382775         97 LLQYLEGLQGS-HRARLTQEAEE 118
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