Conserved Protein Domain Family
DUF4618

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pfam15397: DUF4618 
Domain of unknown function (DUF4618)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 238 and 363 amino acids in length. There are two conserved sequence motifs: EYP and KCTPD.
Statistics
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PSSM-Id: 464704
Aligned: 20 rows
Threshold Bit Score: 241.78
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_023363123  30 VKFRKDSLAELKQNVDSLTVSNQELAKKIQDVEAFTAEKVRKLLRQQDVFGTLISTLEYANHIQMQDMKSKLEKWEAETK 109
1_pfamImport   1 ILARKKSVEQYSQLKDELNTNNATLKDHIISCESTTHKGVTKLLEKYEKYTSASKVLSKNHVVQIETAQAELNSMAGKFA 80 
XP_007474540 104 LKFRRASLEELKKHVGSLTITNQELAKKIQDIEARTTGKVRKLLQQQDLFGTLISTLDFASHKEMERIKDKLQKWETQAS 183
XP_008117025 111 SKSRRHSLDELKHHSKVLLKKNLGLMEEIKEMDDETAKEARDLLQQYEMFGTVITTLWDSSQNQLGIAKSELLEKDKIVE 190
XP_002121242 125 IEARKKSLEQYTKLKQDLKSNNEALKQEIISREDTTHVGVRKLLEKYERYTSASKVLERNHSNQVEAARKDLQTKAEMFA 204
XP_002604682 110 IKARMQTMDEYTKRYEYLLSENKKLQAEIQGTEKQTHRDTTKLLRKYEKCRGAVSTINSKFHEDLETAQADLEETTERLN 189
XP_003383783 108 IVRKKETLEKYRSHLAQLQEKNLQLVMAIQSTDETTHEKVSHSLDKYHKFKGVISKVKQKGATELKDSIEDLESLKSEME 187
XP_023405888 104 LRNRRTSLQMLQNHENFLTKVNQDLVKTIQDMEDSTALKVREMLQQQTILGNVIDILEYSNKKRLEELKCELQEWEEKEE 183
XP_012668685 104 IKNRKTLLQELRNHETFLTKLNLDLISTIQDMEDSTALNVRAMLQQQDILTTIVDILETSNNKRLQQLKSELQEWEEKEE 183
XP_003273521 105 LRNGRTALRELQSHENFLTKLNEELIETIQDMESSTTLNVRALLQQQDILATIINILEYSNKKRLQELKSELQEWEEKKK 184
XP_023363123 110 VRVNDLEQQLTKLKRKINNAQEELNFLSTYMDHEYPIKSLEIANLVRQVQGVKDSSQNELDELEEIRKNVLQTLSKKLMV 189
1_pfamImport  81 KEIADLTDESQYLDAKVQVLLQDLQVLRTYKDKEYPVKAMCIAKLSNNVGNLSIDQRDEMEELKRIISGERMKMLAHRMN 160
XP_007474540 184 IKLNELQRQMTKVKAKIHKTKEELNFLSTYMDQEYPIKSVQIENLMRQIQDVKDNNQEDLEELEELGKEVLQMLSKKLMV 263
XP_008117025 191 KNVGKLDAEMARMNTKVQALQDEVNVLRSYMDKEYPVKAVQISSLMRSIRNLSERQQYELEDIEDLSRRFLETLSGKAFK 270
XP_002121242 205 NNISELANEAEYLDGKVQSYLYDLQVLRTYKDKEYPVKAMCIAKLTNNVGNLSTEHRMQLEELKRIINGERGKMEGHHVT 284
XP_002604682 190 RDLENLHGELRAVEQRLKLKQEELHVLVTYKDKEYPSKALKISGLETEIKDLAAEQEEELDELNRIILIERTSFERQKVA 269
XP_003383783 188 STLAKMRLELHEEEVMLTKSSKQLHTLLNYKEKDYPLKQVKIEQLQMNLDYLDEMHEREELELEESLQEERNKFERKMDE 267
XP_023405888 184 SQINYLEKQVEQLDAKIKKMHEEVNFLSTYMDHEYPVRLVQIANLLRQLQQTRDRQQDELDELSEMRKMVLQSLSNKIQR 263
XP_012668685 184 SKMKGLEQQVKQLDAKIKKTNEEVSFLSTYMDHEYPAKSVQITNLVRQLQQVKDSHQEELDDLSELRKRVLKSLADKMQN 263
XP_003273521 185 CKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSVKSVQIATLMRQLQQVKDSQQDELDDLSEMRRKVLESLSNKIQK 264
XP_023363123 190 KSEKVLNIMAKRTILP-YQTALMKRTLSNQLLLKQMVQFRVHIDRMKKELPKLKAQVKDLQMKRQ-DPREVIFANI-LLR 266
1_pfamImport 161 QTEAIVDHAAEDAFKScTSRSLQLLSRKNQVIAYEIMQNRQEISELTLIVEQLENEVKILSNMAEtNVRKYVFPELkVMD 240
XP_007474540 264 NSEQVLYVMAKKIISP-YQVALMKRTLSNQQLLKQMVQFRVHIDYMKEQLPKLKAEVKALERHRK-HPREVIFEDI-LLR 340
XP_008117025 271 EEEHVFQTIAEKQLMQ-YQDGLTQMNRNNLELKRQIAGQKELIAEMVKEVKELHRSIIKLHHSTG-DPRNVIFADV-LLR 347
XP_002121242 285 KTQEIVGSAARNAFDScTSRSLQQLSRKNQVLMYEIVQNKQDIEELKIVVQQLQYEVDALANMREtNVRKFVFPELnIMD 364
XP_002604682 270 DNQAMTSNVTEKSISA-MHGSLKDMALQNAVMKKEIEVHRGERETLKQDISLLEAELKQLIKDPKsQVLQQIFPHF-FPK 347
XP_003383783 268 IRRQLETKASENWLAQ-MKRSVFARAIHNKVMEKELELQRKNEQELLNDINKLKSAIQKMMCEAG---KNSILISP-LMK 342
XP_023405888 264 KEKGLLKSLVMKVLDP-HQEVLVQNTRDNQEMLKYMDEFRDFIDQFTEEMPLLRAQVQQLQAQIR-DRREIIFEDV-LLR 340
XP_012668685 264 KKINILKSLVVKTQSP-YQDALLQRTQNSQAMLRCMDKFKKFIDQFEEEIPILRAEVEELQKKTL-EPREIIFQDV-LLR 340
XP_003273521 265 KKKKILSSVVAETQRP-YEEALLQKMWESQDFLKCMQRFREFIDQFKENMPVLRAEVEELQAQTR-EPREVIFEDV-LLR 341
XP_023363123 267 KPKCTPDMDVILNIPPEEILP 287
1_pfamImport 241 TPMCHPDEDVILDIPTQQMLP 261
XP_007474540 341 KPKCTPDMDVILNIPQEEVLP 361
XP_008117025 348 RPKCMPDMDVVLDIPTDEDFP 368
XP_002121242 365 KATCQPDEEIYLDIPKLQLLP 385
XP_002604682 348 EPKCTPDMDVVLDIPTQECLP 368
XP_003383783 343 LGKCTSQTEIQLEIPTNQELP 363
XP_023405888 341 RPKCTPEMDVILNIPVEELLP 361
XP_012668685 341 RPKCTPDMDVILNIPMEEVLP 361
XP_003273521 342 RPKCTPDMDVILNIPVEEPLP 362
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