1NHC,1HG8


Conserved Protein Domain Family
Glyco_hydro_28

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pfam00295: Glyco_hydro_28 
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Glycosyl hydrolases family 28
Glycosyl hydrolase family 28 includes polygalacturonase EC:3.2.1.15 as well as rhamnogalacturonase A(RGase A), EC:3.2.1.-. These enzymes is important in cell wall metabolism.
Statistics
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PSSM-Id: 425588
Aligned: 13 rows
Threshold Bit Score: 278.112
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1NHC_A        20 DVVLSSIEVPA--GETLDLSDAA------DGSTITFEGTTSFG----------YKEWKGP--LIRFGGKDLTVTMADG-A 78 
A2R5S4        47 TITLNNIEVPA--GTTLDLTGLT------SGTKVIFEGTTTFQ----------YEEWAGP--LISMSGEHITVTGASG-H 105 Aspergillus nig...
A2QAH3        52 DVVLSSIEVPA--GETLDLSDAA------DGSTITFEGTTSFG----------YKEWKGP--LIRFGGKDLTVTMADG-A 110 Aspergillus nig...
Q2UHL4        51 nIVLKNIAVPA--GETLDLSKAK------DGATITFEGTTTFG----------YKEWKGP--LIRFGGNKITVTQAAG-A 109 Aspergillus ory...
B8N7Z8        48 TITLSNIEVPA--GETLDLTGLN------DGTTVIFSGETTFG----------YKEWEGP--LISVSGTNIKVQQASG-A 106 Aspergillus fla...
EMD60429      47 DIVISGMTVPA--GTTLDLTGLK------SGTTVTFQGTTTFG----------YKEWAGP--LISVSGTNIKVVGAAG-H 105
P47180        45 SIVIKDLTVPA--GQTLDLTGLS------SGTTVTFEGTTTFQ----------YKEWSGP--LISISGSKISVVGASG-H 103 Saccharomyces c...
CCT72952      45 NIVLAGFQVPT--GKQLDLSKLK------AGTTVTFEGKTTFA----------TTADNDFd-PIVISGSGITITGASG-H 104
Q6D880        64 QGKAVRLSAGSssVFLSGPLSLPsgasllIDKGVTLRAINNAKsfenspsscgVVDKNGKgcDAFITAVSTTNSGIYGpG 143 Pectobacterium ...
P05117       105 SRTPVQFVVPKnkNYLLKQITFSgp--crSSISVKIFGSLEAS----------SKISDYKdrRLWIAFDSVQNLVVGGgG 172 tomato
XP_009124086  49 APAPSQVLIPKg-DFKLGETVMTgp--ckSPIEFTLQGNVKAD----------GGSTQGK--DRWVVFEKINGFKLNGgG 113
P26216        70 GTGKQTILIPKg-DFLVGQLNFTgp--ckGDVTIQVDGNLLAT----------TDLSQYKdhGNWIEILRVDNLVITGkG 136 Zea mays
1HG8_A        20 NIVLNGFQVPT--GKQLDLSSLQ------NDSTVTFKGTTTFA----------TTADNDFn-PIVISGSNITITGASG-H 79 
1NHC_A        79 VIDGDGS--------RWWDSKGTn----GGKTKPKFMYIHDVE-DSTFKGINIKNTPVQAISVQ-ATNVHLNDFTIDNSD 144
A2R5S4       106 LINCDGA--------RWWDGKGT-----SGKKKPKFFYAHGLD-SSSITGLNIKNTPLMAFSVQ-ANDITFTDVTINNAD 170 Aspergillus nig...
A2QAH3       111 VIDGDGS--------RWWDSKGTn----GGKTKPKFMYIHDVE-DSTFKGINIKNTPVQAISVQ-ATNVHLNDFTIDNSD 176 Aspergillus nig...
Q2UHL4       110 VIDGQGS--------RWWDGKGTn----GGKTKPKFIYAHKLQ-SSTIKGLHVKNSPVQVFSVQ-GNDVHLTDITIDNSD 175 Aspergillus ory...
B8N7Z8       107 KIDGDGS--------RWWDGKGGn----GGKTKPKFFYAHKLD-SSSITGLQIYNTPVQGFSIQ-SDNLNITDVTIDNSA 172 Aspergillus fla...
EMD60429     106 TIDCAGQ--------KWWDGKGSn----GGKTKPKFFYAHSLT-TSSISGLNVKNTPVQAFSINgATDLTLDHITIDNSA 172
P47180       104 TIDGQGA--------KWWDGLGd-----SGKVKPKFVKLALTG-TSKVTGLNIKNAPHQVFSINkCSDLTISDITIDIRD 169 Saccharomyces c...
CCT72952     105 VIDGNGQ--------AYWDGQGSnn--qDNPKPDHFIVVKKTTgNSKITNLNIQNWPVHCFDITgSSDLTISGLILDNRA 174
Q6D880       144 TIDGQGGvklqdkkvSWWELAADakvkkLKQNTPRLIQINKSK-NFTLYNVSLINSPNFHVVFSdGDGFTAWKTTIKTPS 222 Pectobacterium ...
P05117       173 TINGNGQ--------VWWPSSCKinkslPCRDAPTALTFWNCK-NLKVNNLKSKNAQQIHIKFEsCTNVVASNLMINASA 243 tomato
XP_009124086 114 TFDGEGNa-------AWKANNCHkt--fECKKLPISVRFDFVD-NAEIKDITSLDAKNFHFNVIsGKNMTFDNIKIIAPA 183
P26216       137 NLDGQGPa-------VWSKNSCTkk--yDCKILPNSLVMDFVN-NGEVSGVTLLNSKFFHMNMYrCKDMLIKDVTVTAPG 206 Zea mays
1HG8_A        80 VIDGNGQ--------AYWDGKGSns--nSNQKPDHFIVVQKTTgNSKITNLNIQNWPVHCFDITgSSQLTISGLILDNRA 149
1NHC_A       145 GDdn--------ggHNTDGFDISESTGVYISGATVKNQDDCIAINSGE------SISFTGGTCSGGHGLSIGSVGGRDD- 209
A2R5S4       171 GDtq--------ggHNTDAFDVGNSVGVNIIKPWVHNQDDCLAVNSGE------NIWFTGGTCIGGHGLSIGSVGDRSN- 235 Aspergillus nig...
A2QAH3       177 GDdn--------ggHNTDGFDISESTGVYISGATVKNQDDCIAINSGE------SISFTGGTCSGGHGLSIGSVGGRDD- 241 Aspergillus nig...
Q2UHL4       176 GDnn--------ggHNTDAFDVSESNGVYITGANVKNQDDCLAINSGE------NIEFTGATCSGGHGISIGSIGNRDS- 240 Aspergillus ory...
B8N7Z8       173 GTae---------gHNTDAFDVGSSTYINIDGATVYNQDDCLAINSGS------HITFTNGYCDGGHGLSIGSVGGRSD- 236 Aspergillus fla...
EMD60429     173 GDsa--------ggHNTDAFDVGSSSGITISNANIKNQDDCVAINSGS------NIKVTNCQCSGGHGVSIGSVGGRKD- 237
P47180       170 GDsa--------ggHNTDGFDVGSSSNVLIQGCTVYNQDDCIAVNSGS------TIKFMNNYCYNGHGISVGSVGGRSD- 234 Saccharomyces c...
CCT72952     175 GDkpnaksgglpaaHNSDGFDISSSDHVTLDNNYVYNQDDCVAVTSGT------NIIVSNMYCSGGHGLSIGSVGGKSN- 247
Q6D880       223 TA------------RNTDGIDPMSSKNITIAYSNISTGDDNVAIKAYKgraetrNISILHNDFGTGHGMSIGSETMG--- 287 Pectobacterium ...
P05117       244 KS------------PNTDGVHVSNTQYIQISDTIIGTGDDCISIVSGSq-----NVQATNITCGPGHGISIGSLGSGNSe 306 tomato
XP_009124086 184 ES------------PNTDGIHLGRCEGVKILNTKIATGDDCISVGDGMk-----NLLIEKVVCGPGHGISVGSLGRYGWe 246
P26216       207 DS------------PNTDGIHMGDSSGITITNTVIGVGDDCISIGPGTs-----KVNITGVTCGPGHGISIGSLGRYKDe 269 Zea mays
1HG8_A       150 GDkpnaksgslpaaHNTDGFDISSSDHVTLDNNHVYNQDDCVAVTSGT------NIVVSNMYCSGGHGLSIGSVGGKSD- 222
1NHC_A       210 NTVKNVTISDSTVSNSANGVRIKTIY--KETGDVSEITYSNIQLSGITdYGIVIEQDYEN-GSPTGTP-STGIPITDVTV 285
A2R5S4       236 NVVKNVTIEHSTVSNSENAVRIKTIS--GATGSVSEITYSNIVMSGISdYGVVIQQDYED-GKPTGKP-TNGVTIQDVKL 311 Aspergillus nig...
A2QAH3       242 NTVKNVTISDSTVSNSANGVRIKTIY--KETGDVSEITYSNIQLSGITdYGIVIEQDYEN-GSPTGTP-STGIPITDVTV 317 Aspergillus nig...
Q2UHL4       241 NTVKNVKVADSTVVDSDNGIRIKTIS--GATGSVSGVTYENITLKNIKkNGIVIEQDYKN-GGPTGKP-TTGVPITDLTV 316 Aspergillus ory...
B8N7Z8       237 NTVEDVTISNSKVVNSQNGVRIKTVY--DATGTVSNVKFEDITLSGITkYGLIVEQDYEN-GSPTGTP-TNGIKVSDITF 312 Aspergillus fla...
EMD60429     238 NTVKGVVVSGTTIANSDNGVRIKTIS--GATGSVSDITYENITLKNIAkYGIVIEQDYLN-GGPTGKP-TTGVPITGVTL 313
P47180       235 NTVNGFWAENNHVINSDNGLRIKTVE--GATGTVTNVNFISNKISGIKsYGIVIEGDYLN-SKTTGTA-TGGVPISNLVM 310 Saccharomyces c...
CCT72952     248 NVVDGVQFLNSQIVNSENGCRIKSNS--GTTGTINNVTYQNIALTNISkYGVDVQQDYLN-GGPTGKP-TNGVKISNIKF 323
Q6D880       288 --VYNVTVDDLKMNGTTNGLRIKSDK--SAAGVVNGVRYSNVVMKNVA-KPIVIDTVYEK-KEGSNVP-----DWSDITF 356 Pectobacterium ...
P05117       307 AYVSNVTVNEAKIIGAENGVRIKTWQ--GGSGQASNIKFLNVEMQDVK-YPIIIDQNYCDrVEPCIQQ-FSAVQVKNVVY 382 tomato
XP_009124086 247 QDVTDINVKNCTLEGTDNGLRIKTWPsaACTTTAAGIHFEDIILNKVS-NPILIDQEYCP-WNQCNKNkPSTIKLVDITF 324
P26216       270 KDVTDINVKDCTLKKTMFGVRIKAYEdaASVLTVSKIHYENIKMEDSA-NPIFIDMKYCP-NKLCTANgASKVTVKDVTF 347 Zea mays
1HG8_A       223 NVVDGVQFLSSQVVNSQNGCRIKSNS--GATGTINNVTYQNIALTNIStYGVDVQQDYLN-GGPTGKP-TNGVKISNIKF 298
1NHC_A       286 DGVTGTLEDdATQVYILCGDGS-CSDWTWSGVDLSG-G---KTSDKCENVP-------SGASC 336
A2R5S4       312 ESVTGSVDSgATEIYLLCGSGS-CSDWTWDDVKVTG-G---KKSTACKNFP-------SVASC 362 Aspergillus niger CBS 513.88
A2QAH3       318 DGVTGTLEDdATQVYILCGDGS-CSDWTWSGVDLSG-G---KTSDKCENVP-------SGASC 368 Aspergillus niger CBS 513.88
Q2UHL4       317 NGVTGSVASkATPVYILCGKGS-CSDWTWKGVSISG-G---KKSDKCQNIP-------SGASC 367 Aspergillus oryzae RIB40
B8N7Z8       313 DKVTGTVESdATDIYILCGSGS-CTDWTWSGVSITG-G---KTSSKCENVP-------TGASC 363 Aspergillus flavus NRRL3357
EMD60429     314 KNVAGTVTSsGTEIYVLCGTGS-CSGWNWSGVSITG-G---KKSSSCLNVP-------AGASC 364
P47180       311 KDITGSVNStAKRVKILVKN---ATNWQWSGVSITG-G---SSYSGCSGIPs-----gSGASC 361 Saccharomyces cerevisiae S288C
CCT72952     324 TKVTGTVASsAQNWYILCGDGS-CSGFTFSGNAITG-G---GKTSSCNYPT-------NTCps 374
Q6D880       357 KDVTSETKG---VVVLNGENAKkPIEVTMKNVKLTS-----DSTWQIKNVN-------VKk-- 402 Pectobacterium atrosepticum
P05117       383 ENIKGTSAT-KVAIKFDCSTNFpCEGIIMENINLVGeSg-kPSEATCKNVHfnnaehvTPHCT 443 tomato
XP_009124086 325 RNIRGTSGN-KDAVKLLCSKGHpCENVEIGDINIDYtGpdgPPTFECTNVTpk----lVgtqn 382
P26216       348 KNITGTSST-PEAVSLLCTAKVpCTGVTMDDVNVEYsGtnnKTMAICTNAKgstkgclKELAC 409 Zea mays
1HG8_A       299 IKVTGTVASsAQDWFILCGDGS-CSGFTFSGNAITG-G---GKTSSCNYPT-------NTCps 349
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