6Q8W,6RFS,5XTC


Conserved Protein Domain Family
NADHdh

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pfam00146: NADHdh 
NADH dehydrogenase
Statistics
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PSSM-Id: 459690
Aligned: 411 rows
Threshold Bit Score: 117.574
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6Q8W_Q           16 KALLVVvgLLTAFA-FMTLIERRLLARFQVRMGPnrvgPfGLLQPLADAIKSIFKEDIVVAQADRFLFVLAPLISVVFAL 94  Thermus ther...
jgi:Ppro_2793     7 VLVNVI--LVLALApLFQGVLRKVTARIQSRQGP------PINQPYLDILKLLGKDDIESGEA-PVLQRFAAYLPLAVML 77 
WP_013317237     13 ALLQAV--LLMAAApLLSGLSRVIRAKMHSRQGP------GVLQDYRDIVKLLRRQEMAPEHS-GGVFRLMPFILLGTML 83  Dickeya dada...
P77858           14 ALAQAV--ILLMLTpLFTGISRQIRARMHSRRGP------GIWQDYRDIHKLFKRQEVAPTSS-GLMFRLMPWVLISSML 84  Escherichia ...
CCH:MU9_3454     15 avvQAI--FLLLLTpLFTGISRQIRAKMHSRQGP------GIMQDYRDITKLLKRQSVAPRDS-GFIFRVMPYVLLSSML 85 
Q6L0T8           31 TLTQIV--TVIFISpLIAGIYENLKSKVELKKGP------SVFQPYYDLFKYIKKETIVPYNA-GFLFIYGPYLVFAILV 101 Picrophilus ...
WP_012514347      7 gilQIV--IFIALApAIKGFIHKIKLNLRGQKGP------SILQPYKDLIKLFRKEPVISKDA-SFISKIAPIVVLLATI 77  Hydrogenobac...
CBK43927         10 vvvqLA--LLLALSpFVVGLIRKVKARLQCRRGA------SLFQPYADLAKLFRKQPVISSTT-SWIFTAAPYIVFASTV 80 
jgi:Smar_1060     8 yvISFI--VFLFIPpLLDGLERKIRARLHSRVGP----P-TIFQTWYDIRKLLAKEQVATDTFVNTFFIVS--ILFTTSM 78 
agres:bpr_I1405   9 ALIYIL--LAPIIGgLMSGLDRVFSARMQGRQGP------PIIQPFYDVNKLLHKQTTVVNGIQ---------VLFVTVY 71 
6Q8W_Q           95 LAFGLIPFGppgsffgyqpwviNL-------DL--GILYLFAVSELAVYGIFLSGWASGSKYSLLGSLRSSASLISYELG 165 Thermus ther...
jgi:Ppro_2793    78 TIACLVPMGfka-----------------plSGsgDVLLLILLMTLAGICTLLAGLASGSTYSLIGINREMMCMITLEPL 140
WP_013317237     84 LVAMTLP----------------AvtdgspfGAagDIITLLYLFAVFRFFFSLSGLDSGSTFAGIGASRELTLGILVEPI 147 Dickeya dada...
P77858           85 VLAMALP----------------LfitvspfAGggDLITLIYLLALFRFFFALSGLDTGSPFAGVGASRELTLGILVEPM 148 Escherichia ...
CCH:MU9_3454     86 LLAMALP----------------VvtttslfSGagDLIIILYIFALFRFFFSLSGLDTGSPFAGIGASRELTLGVLVEPI 149
Q6L0T8          102 LISFIIP---------------VVipepvyfTAsaDFLGGALLFSLASFIKILGSVDSGSNYSVMGAARASSFTYLGEAT 166 Picrophilus ...
WP_012514347     78 ISASFIP----------------IfspntllSFtgDVIAFMYVLGLSTFFIALYGLDQGSSFGGLGSAREMTIASLAEPT 141 Hydrogenobac...
CBK43927         81 AAGLLMP----------------VfvshtplNFagNIIALVYLLALGTFFLILAGLDAGSAFGGMGSSREAIVATLAEPA 144
jgi:Smar_1060    79 LTIPLMPFGsig----------------ifsNSrnSLILFIILLASSQLLWVALSLSPGNPFSTIGVYREALLEMVNELF 142
agres:bpr_I1405  72 LIFTIFTgs--------------------lfFAggDMLLVFFALSMSEVMLVLAAFSTNGPYSIMGAQRELLQMMCYEPM 131
6Q8W_Q          166 LGLALLAPVL-L------VGSL-----------NLNDIvnwqk---ehgwlFLYaFPAFLVYLIA-SMAEAARTPFDLPE 223 Thermus ther...
jgi:Ppro_2793   141 FAVAIVMGAL-A------KGSF-----------NLDEVlsgsvy--gangmALSgFAMLVIMLLA-FQAFVGRAPFDISE 199
WP_013317237    148 LMLALLVVAL-V------AGST-----------NIGNIsvklas--ghwasPTAtALALLACAFA-TFIEMGKIPFDVAE 206 Dickeya dada...
P77858          149 LILSLLVLAL-I------AGST-----------HIEMIsntla---mgwnsPLTtVLALLACGFA-CFIEMGKIPFDVAE 206 Escherichia ...
CCH:MU9_3454    150 LFLGLLVVAL-I------AGST-----------NIGSIsavms---qgwvsPTAtFLAMLACGFA-TFIEMGKIPFDVAE 207
Q6L0T8          167 LITVFFAVAF-ItrtdnpYVTNhylvmhpfsylTLLHI------------------FASVAFFMV-FLFETGRIPVE-SE 225 Picrophilus ...
WP_012514347    142 LMMIMFTFSL-E------YGTS-----------NISEIfvkahs--hsfnvPIAyVFSLLALFFV-SMAENARIPFDNPE 200 Hydrogenobac...
CBK43927        145 MMLSILSIAL-T------AGST-----------NLSTIvhqsalmegvvvaPPAhLMALAALFIV-TLAETGRVPVDNPA 205
jgi:Smar_1060   143 LILTGFGLMVyI------GGTSf---------rDLTNIn------------YSAiYILFIVLLIViSYVSSGRVPFDLAE 195
agres:bpr_I1405 132 TLLVAIGFYY-A------NGSFmvddlihseipAIAQI------------------PGFFIGFVFiLIIKLRKSPFDLST 186
6Q8W_Q          224 A---EQEL---VGGYHTEYSSIKWALFQMAEYIHFITASALIPTLFLGGwtmPvl----------evPYLW------MFL 281 Thermus ther...
jgi:Ppro_2793   200 A---ETEI---MEGAMVEYSGPKLALFQYANMAKLVVYSALFVSLFV-----Pwgsgl-----aapiSFIL------FWV 257
WP_013317237    207 A---EQEL---QEGPLTEYAGAGLALVKWGISLKQVVVATLFLSIFV-----PfgkaetltavsllwGSLA------LII 269 Dickeya dada...
P77858          207 A---EQEL---QEGPLTEYSGAGLALAKWGLGLKQVVMASLFVALFL-----PfgraqelslaclltSLVV------TLL 269 Escherichia ...
CCH:MU9_3454    208 A---EQEL---QEGPLTEYSGSGLALVKWGIGLKQVVVAVLFLSIFF-----PfgsasvltagslllALGL------MLV 270
Q6L0T8          226 G---LMELgmiDGAFNYEYSGKLLAINKWSGYMKNYLLGSVLLNVFIF----Pwfm---------fsGRLFfldvpvMIL 289 Picrophilus ...
WP_012514347    201 T---HLELtmvHEAMILEASGKYLAIFELSSYMKLLLFISIASNIFL-----Pflyss-----nmllNILF------YII 261 Hydrogenobac...
CBK43927        206 T---HLELtmiHEAMLLEYSGRYLALMEWAAGIKLLVFLTLIVNVFA-----PwgiatslapsaiavGLLV------YLG 271
jgi:Smar_1060   196 A---EPEL---ASGVLIEFSGPILGIVLYTNFLKRAILCGFIANLILL----Plksl----------------vndiVLA 249
agres:bpr_I1405 187 ShhmHQEM---VKGLQTDLSGSNLALVEIAEWYDLVLMLGIVGMFFITNn--Pi-------------SRVW------ALI 242
6Q8W_Q          282 KIAFFLFFFIW-----IRATWFRLRYDQLLRFGWGFLFPLALLWFLVTA 325 Thermus thermophilus HB8
jgi:Ppro_2793   258 KVFAMVLLVTT-----IAATHARYRIDQAIRY-FAIMLAVSLVTLAaas 300
WP_013317237    270 KLVVVFVIAAV-----IENSLARGRFLLTGRVTWL-GFGVAALAFVFYL 312 Dickeya dadantii
P77858          270 KVLLIFVLASI-----AENTLARGRFLLIHHVTWL-GFSLAALAWVFWL 312 Escherichia coli K-12
CCH:MU9_3454    271 KLLVIFVLASL-----VENSLARGRFLLTHHVTWL-GFGVAALGFVFYL 313
Q6L0T8          290 KWLLLMLILLF-----IETTLSKLRLYKVQDF-LATAFTLSIAFLIVsv 332 Picrophilus torridus
WP_012514347    262 KVIIFSIPIAL-----LELSVAKFRFFRIPDLLMI-SFALATLGFVLYY 304 Hydrogenobaculum sp. Y04AAS1
CBK43927        272 KVAALALVIGV-----IESMFAKLRLFRVPEMLGA-AFILSLLALVFFY 314
jgi:Smar_1060   250 ALFYLLLFFIWliyaiVSILLARSRIDLAPRTMF--VVYLLFYSIIVVL 296
agres:bpr_I1405 243 AVAVVFFLETL-----IDNLFPRVKYKTMLIVTWSVILAFAGTNLLILN 286
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