Conserved Protein Domain Family
DUF4500

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pfam14937: DUF4500 
Domain of unknown function (DUF4500)
This family is found in eukaryotes. The function of this protein remains unknown. The gene which encodes for this protein is named chromosome 6 open reading frame 162 (C6orf162) and is found between the chromosomal positions 6q15-q16.1. It is thought that this protein may be an important part of membrane function.
Statistics
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PSSM-Id: 434330
Aligned: 17 rows
Threshold Bit Score: 135.893
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002603789   16 PSSAgPRSPGLRHVQTTTLFRVVNPELFMRPNKMVMAFGLVTITGCIAYLAYMNASKENQRdqLYVNVSSDGT-ETVQRR 94  
NP_001019604   22 AAEPaYRSPGLRGVRTTSLFRAVNPELFIRPNKPVMALGLLALSVCVGYLGYLHAIRDSDQq-LYEAVDSDGE-TYMRRR 99  
XP_006560007    4 KSKKvIPGDGLRSLKSTMLFRAINYELYVKPNKIIMIFGTIAMFGCVGYIVYMQHNSNNTK--YYSVINSNET-IDLKKK 80  
EGI63320        4 NTREtTPGDGLRSLRSTTLFRAVNFELYVKPNKTIMILGIIAMLSCSGYIFYMNTNKKKND--YHIMVKSDET-LELVKK 80  
EFX69126        9 aAIPrVAGDGLRSVKTTGVFRALNFELYVKPNKVIMVLGLLAIAGCTGYLTYMKTKYENMG--YYVAVREDGS-KQLHTK 85  
XP_001604253    5 TEPKhTPGDGIRSLKSTPMFRAINYELYVKPNNVVMALGVIAMTGCVGYILYMRSKYESMG--YYTAVEADGK-ETFKKK 81  
XP_022173902    2 kdRQtAPGDGIRSLKTSRVFRIINFELYSKPNKVIMALGLVSISFTFGYLVYMRHQYEKMG--YYPAVAEDGRhEVYKQR 79  
ETN58991        4 kpKTaAPGDGIRSMRSTNVFRAINFELYAKPNVVVMGIGLVCLSITFGYIAYMRSKYEGLG--YYTAVQEDGK-EVFVKR 80  
1_pfamImport    1 PEAGaAAGDGIRSIKTTNVFRLINFELYTKPNLVIMCLGGAALAGVFGYIAYMRHKYEALG--YYVAVQEDGK-EVFTKK 77  
XP_002047464    3 EKQTqKPGEGIRSMRSTSVFRLINFELYTKPNKIIMGLGLAAITGVFGYIAYMRYKYENLG--YYVAVREDGR-EEFVKK 79  
XP_002603789   95 RSKW 98  
NP_001019604  100 TSRW 103 
XP_006560007   81 TSKW 84  
EGI63320       81 VSKW 84  
EFX69126       86 KSRW 89  
XP_001604253   82 VSKW 85  
XP_022173902   80 QSKW 83  
ETN58991       81 KSKW 84  
1_pfamImport   78 QSKW 81  
XP_002047464   80 KSNW 83  
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