Conserved Protein Domain Family
FeFe_hydrog_A6

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NF040763: FeFe_hydrog_A6 
NADH-dependent [FeFe] hydrogenase, group A6
Statistics
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PSSM-Id: 468723
Aligned: 85 rows
Threshold Bit Score: -1
Created: 24-Apr-2023
Updated: 4-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_073168671   5 INITINGYPVDVKKGKTILEAAEEQGVRIPTLCYHKDLCVAGNCRVCVVEVVGQKRLSAACATPCEDGMEILTNSLKVRN 84  Tangfeifania di...
WP_124991984   5 VNLTINGIAVSVEENKTILEAAKHLHIKIPTLCYHKDLCVAGNCRVCVVEQVGNHKLVASCATPVAEGMEINTNTLKVRN 84  Labilibaculum e...
WP_079556276   5 VTLKIDSISVSVKQGTSLLDAARSINIKIPTLCHHEDLCVAGNCRVCMVEQKGSDRLLPACAIPASDGMEIHTNSMKVRN 84  Alkalitalea sap...
WP_012635247   2 VKINIDGLDLEVRDGISILEAARQAHIKIPTLCYEEGLSVYGGCRLCVVEIEGEALLKPACATEVNDGMVIKTHSPKVRD 81  Halothermothrix...
WP_013406264   2 LNIEIDGLKLSVEEGISILEAAKKANIYIPTLCYEKELSVYGGCRLCVVEVEGEELLKPACATSVEGGMKIKTHSRKVRK 81  Halanaerobium h...
WP_006928134   2 FTVEINGRKIEARNGETILDVLNRAGAKVPTLCHLKGLFPSGACRICSVEVEGFNTLIPSCAYPVQDGMIIKTNTPRVVK 81  Caldithrix abyssi
WP_041356083   4 IELTINDIKVKAEEGMTILEAAKSVGIHIPTLCHMKDLFPTGACRICVVEVDGMRNLTPSCAYPVTEGMKVQTNSPRVRV 83  Melioribacter r...
WP_073071554   2 VKIFINNKEYEVPENITVLEAAQKIGLQIPTLCHHPELEPIGACRVCVVEIEGARTLQPACTTKVYDGMKIKTNSDRVVN 81  Thermosipho atl...
WP_014450900   2 VTIYINGDKHEVEEGKTILEVASQLGYHIPTLCHHPELQPIGACRICVVEVEGFKTLQPACATKVADGMVIRTNTERVEN 81  Fervidobacteriu...
WP_161848847   4 VSIVINGRTYTVDSQMTVLEACQKVGVYVPTLCHHPLLEDVGACRVCAIEIEGARTLMTACTTKVAEGMKIKTSSDRVER 83  Athalassotoga s...
WP_073168671  85 SRKHIIELLLSEH----NADCTKCYRNGSCELQELASEYKIMTQDFLElapMKNYTIDMFSPSIMKDDSKCIRCQRCVRT 160 Tangfeifania di...
WP_124991984  85 CRKHIIELLLTEH----REECTKCYRNGHCELQALSAEYQITNQDFIDlvpDKNYTVDRLSPAIEKDDSKCIRCQRCVRT 160 Labilibaculum e...
WP_079556276  85 ARKQILELLVSEH----RAECTTCYKSGNCELQELSHEYILGENAFINlipFKEYTIDYYSPSIIKDDSKCIRCQRCVRT 160 Alkalitalea sap...
WP_012635247  82 VRRTLFELIVASHnidcQLNCLTCSRAGSCELREIAEDIGVSNIRLATy-dKGY-RDDRSSYSIVREPNKCITCGRCIRK 159 Halothermothrix...
WP_013406264  82 LRQNLFELIIATHnidcQLNCLTCSRNRSCELKKIAEDIGIEKVRLDPi-rGGH-SVDNSSYSIVREPDKCISCNRCIRK 159 Halanaerobium h...
WP_006928134  82 ARKTIIELLLANH----VQDCLYCVRNGDCELQELAAVYGVRERRYPAg-pEKR-PVDVSSPSIVHDQNKCILCGKCVRT 155 Caldithrix abyssi
WP_041356083  84 ARKTIVELLIENH----PQDCLICVRNKNCELQDLSERYNVREHRYVGe-kKNH-AIDISSPSMERDPAKCILCGRCVRT 157 Melioribacter r...
WP_073071554  82 SIKFNLSLIMANH----PNDCMYCEADQRCELKKLVHIYDVRPLFPPt--dLSD-VFDDSSPSIQRDLSRCIKCQRCVRV 154 Thermosipho atl...
WP_014450900  82 AVKLNLELVMANH----PHECMYCEADGRCELQKLVHMYDVQPTFGISv-sFPK-YIDTSSPSIHRDLTKCIKCQRCVRV 155 Fervidobacteriu...
WP_161848847  84 ALKDNLALLLSRH----PNDCMTCDVNGRCEFQNLINLYDIHDIYPKDl-rNVE--FDSSSNAIFRDLNKCINCGRCVRV 156 Athalassotoga s...
WP_073168671 161 CSELQGVNALTVAYKGDKMKIATFFEKPMNDVVCTNCGQCVNHCPTGALVEKNYIEEVWEAIADPT-KHVVVQTAPAVRV 239 Tangfeifania di...
WP_124991984 161 CAEIQSVGAIAVAHKGSEMKISTFFDRSLDEVVCTNCGQCIVHCPTGALTEKSYVEKVWDALADPD-THVIVQTAPAVRV 239 Labilibaculum e...
WP_079556276 161 CDQLQNIGALTVSKKGSEMKISTFFEKPIYQVVCTNCGQCVNRCPTGALTEKNYVEEVWSAINDEK-KYVVVQTAPAVRI 239 Alkalitalea sap...
WP_012635247 160 CEEVQEVGIFTTANRGPATVVTTFKEKGMGNVECTNCGQCIHACPTGALHEVYHYEKVWEVLHDRD-KYVVVQTAPAVRV 238 Halothermothrix...
WP_013406264 160 CEEIQGIGIFTTANRGPDTVVTTFKDMGMGNVECTNCGQCILSCPTGALHEVYQKEKVWQALENEN-KHVIVQTAPAVRV 238 Halanaerobium h...
WP_006928134 156 CEEIVGVAAIDFVHRGSKTVIAPAFEFNLNVSSCIGCGQCVLVCPTGALRERSSLKEVTDALQNPE-KFVVVQHAPAVSV 234 Caldithrix abyssi
WP_041356083 158 CNEIQKIGAIDFTNRGFKSNVTTPFNKGLNISDCILCGQCILVCPTAALRERSHAKEVVNALNDKK-KFTVVQVAPAVRA 236 Melioribacter r...
WP_073071554 155 CSEIQGMNIYSMIERGYKTIPQTAFDVPVYETDCISCGQCANLCPVGAIYETPDWKKVLRLIERKD-KILIAQTAPAVRV 233 Thermosipho atl...
WP_014450900 156 CSEIQGMNIYSMIERGYETVPETEFGLPVYETNCISCGQCAYLCPVGAIYEAPTWKKLLHMLENKNgKVFIAQTAPSVRV 235 Fervidobacteriu...
WP_161848847 157 CQDVQGLSIYTLSNRGSESLPVPAFGLEMKYTDCIGCGQCSAVCPVGAITEEPDYKRVDVHLRKHD-KIMIVQTAPATRV 235 Athalassotoga s...
WP_073168671 240 GLGEELGMKPGERVTGKMAAALKRLGFNSVLDTDFTADLTIVEEGNELLTRLKkalVDKdpdvklpMATSCSPGWIKYIE 319 Tangfeifania di...
WP_124991984 240 GLGEELGLGLGTRVTGKMVSALKRLGFDSVLDTNFTADLTIMEEGTELLTRLKralVDDdpdvalpMATSCSPGWVKYIE 319 Labilibaculum e...
WP_079556276 240 ALGEALGIDPGEIVTGKMVTALRRLGFNSVLDTDFTADLTIIEEGHELLQRLKkvlKDKdknvrlpMTTSCSPGWIKFIE 319 Alkalitalea sap...
WP_012635247 239 ALSEAFGLKPGTIFTGQMVAGLRRLGFDRVFDTNFTADLTIMEEGTELIERLNnngELP-------MFTSCSPGWIKYIE 311 Halothermothrix...
WP_013406264 239 AISEPFSAKAGEISTGQLVAALKRLGFDAVFDTNFAADLTIMEEGTELINRINnkeTLP-------LFTSCSPGWIKFIE 311 Halanaerobium h...
WP_006928134 235 TLAEEFGLKAGSDADRLLVNALRRLGFDRVFDTAFSADLTIMEEASELVERLQnggSIP-------MMTSCSPGWVKFVE 307 Caldithrix abyssi
WP_041356083 237 TLGEEYNLPIGTNVTGKIITGLRRLGFDKVFDTNFGADLTILEEATELINRLGnggVTP-------MFTSCCPGWIKFAE 309 Melioribacter r...
WP_073071554 234 AIGEEFGMEPGSISTGKMVAAVKRLGFDYVFDTNFAADLTIMEEGTELIHRLKeggPFP-------MFTSCCPGWINLLE 306 Thermosipho atl...
WP_014450900 236 AIGEEFGMEPGTVSTGKMVAALRRLGFDYVFDTNFGADLTIMEEAHELLHRLTkggVLP-------MFTSCCPGWVNMVE 308 Fervidobacteriu...
WP_161848847 236 AIGEEFGMEPGHVSTGKMVAALRRLGFDYVFDTNFGADLTIMEEGSELIEQLMghgEHPa-----pMFTSCCPGWINLVE 310 Athalassotoga s...
WP_073168671 320 HLYPEYLDNLSTCKSPQQMFGALAKTYYAKARNLDPENIVSVSIMPCTAKKFEANRPEMHds-----gYRDVDYVLTTRE 394 Tangfeifania di...
WP_124991984 320 HKYPEYLPNLSTCKSPQQMFGALAKTYYAKNVNVVPENIVSVSIMPCTAKKFEANRPEMKds-----gYKDVDFVLTTRE 394 Labilibaculum e...
WP_079556276 320 HIFPDFLPNLSSAKSPQQMFGALAKTFFANKIGVDPASMVSVSVMPCTAKKFEANRPEMYss-----gYQDVDYVLTTRE 394 Alkalitalea sap...
WP_012635247 312 HFYPEFIDNLSTCKSPQQMFGAIAKSYYADKSNIPRDKIVVVSVMPCTAKKFEARRPEME---------GDVDYVLTTRE 382 Halothermothrix...
WP_013406264 312 HFYPQYLSNLSSAKSPQQMFGAVAKNYYAEKAGIDPDDLVVVSVMPCTAKKFEAKRKEMG---------SDVDYVLTTRE 382 Halanaerobium h...
WP_006928134 308 QFYPEFIPNLSTCKSPQQMMGAVIKNIFAREQGISPDKIFSVSVMPCTAKKFEAERPEFShn-----gYADIDAVLTTRE 382 Caldithrix abyssi
WP_041356083 310 QNYPHLLEHLSTCKSPHEMEGAIIKSYYAKKMGLNPEDIFVVSIMPCTVKKFEASRPELSed-----kMPDVDAVLTTRE 384 Melioribacter r...
WP_073071554 307 KQYPEFINNVSSAKSPQQMMSSVIKTYFAKKIGVDPEDIVVVSIMPCTAKKDEITRPQQKikledgreIKATDYVITTRE 386 Thermosipho atl...
WP_014450900 309 KEFPEFIPNLSTTKSPMQIMSS-TREYFAKKLGVAPENIVMVAVMPCTAKKDEIERSQHvv-----ngIKVTDYVITTRE 382 Fervidobacteriu...
WP_161848847 311 KHFPEFIPNISTAKSPQEMLASTIKTYFAKKINVDPKDIFVVSVMPCTAKKDEIVRPQHiy-----ddIQMIDAVITTRE 385 Athalassotoga s...
WP_073168671 395 LAILIKQAGLDFEKLAPAKFDRLMGESTGAGVIFGATGGVMEAALRTAYELVTGRDVPFDNlnIMPVRGLEGVRKATIKI 474 Tangfeifania di...
WP_124991984 395 LAVMIKQAGIEFEKLNDETFDSIMGVGSGAGAIFGATGGVMEAALRTAYEIVTGREVPFDNleIIPVRGLEGVKETTVKI 474 Labilibaculum e...
WP_079556276 395 LALMIKQAGIDFKSLADDNYDSIMGESSGAAVIFGATGGVMEAALRTVYEVVTGREVPFEGlnITPVRGMEGVREATLKI 474 Alkalitalea sap...
WP_012635247 383 LARMIKEAGIDITNLNAEEHDKLMGTSSGAADIFGATGGVMEAALRTAYELVTGEKLGQLD--FKNVRGEAGIKEAEVTL 460 Halothermothrix...
WP_013406264 383 LSGLIKAAGIDFLNIEEKEYDKLLGVSSGAADIFGSTGGVMEAALRTAYELITEKELEKID--FEVLRGDQGIKKASVNI 460 Halanaerobium h...
WP_006928134 383 LIRLIRMYGIEFDSLKPDEPDLPFGKRSTAGKLFGGTGGVMEAALRTAYFLITGKEPQKIV--FEEVRGLKGIREARVKI 460 Caldithrix abyssi
WP_041356083 385 LVRLFKVAGIDFNDLPDDEFDNPLGESTGAAAIFGTSGGVMEAALRTAYFKLSGKELENVD--LTNVRGFDGVKEFSVDI 462 Melioribacter r...
WP_073071554 387 FAKLIKFKEINFMGLPDEEYDNPLGTSTGAGAIFGVTGGVMEAALRTAYEILTEEKLPKLE--FTAVRGLEGIREAEIDI 464 Thermosipho atl...
WP_014450900 383 FAKMLRFKGISFVNLPEEKHDSPLGASSGAGAIFGVTGGVMEAALRTAYEKFTGEKLPRLV--FSEVRGLDGIREAEVDF 460 Fervidobacteriu...
WP_161848847 386 LGRLVKNHRINFLDLPDEDYDAPLGLSTGAAAIFGVTGGVMEAALRTGYELATGKTLPKVE--FKDVRGFAGVKEATVDL 463 Athalassotoga s...
WP_073168671 475 EKPlkewsfldgvELKCAVAHGLVNAKKVMDAVKAGEaDFHFIEIMACPGGCLGGGGQPIPTNPEIRRKRTEAIYAEDGD 554 Tangfeifania di...
WP_124991984 475 EGTveewnflegaELKCAITNGLENAHKLLEAIKRGDkFYHFIEIMACPGGCLGGGGQPFPVDNEIRLQRMNALYEEDRN 554 Labilibaculum e...
WP_079556276 475 DKAlpewdflegvEVKTCVAHGLANAKRVMESVRDGSsNYHFIEIMACPGGCLGGGGQPIPTSPEIRNARSSAIYREDTL 554 Alkalitalea sap...
WP_012635247 461 NGT----------QLKVAVAHGLGNVRKLMELIKSGKe-YHFVELMACPGGCIGGGGQPIPTSEDIRRKRIEALYKIDKN 529 Halothermothrix...
WP_013406264 461 EGF----------ELKVAVVHGLNNAHKIMKMIDEGEe-FHFVEFMACPGGCLNGGGQPISYDEDVVEKRRKAIYQIDKN 529 Halanaerobium h...
WP_006928134 461 ADI----------ELGVAVANGIQNAKALLEQIKAGRdDLHFIEVMTCPGGCVGGGGQPFDTCPASIRTRLQALYQIDRN 530 Caldithrix abyssi
WP_041356083 463 NGS----------TVNVAVVNGIGNVRGILEQIERGEsKYHFIEVMACPGGCINGGGQPIHQKPEKVQKRARALYEIDAK 532 Melioribacter r...
WP_073071554 465 KGK----------KFKVAIAHGTASVKRLLDDMKDGRrYYDFVEIMACLGGCIGGGGQPKSLDPEILQKRANAIYTIDER 534 Thermosipho atl...
WP_014450900 461 KTR----------KLKVAIVNGTANAKRLLKEIKEGKrNYDFVEVMACMGGCIGGGGQPKSLDPDIIKKRARAIYSIDEM 530 Fervidobacteriu...
WP_161848847 464 DGK----------QVKIAVAHGTANVINLLKNIKAGNvKYDFVEIMACYGGCIGGGGQPKSTDPDILKKRSAAIYSIDEA 533 Athalassotoga s...
WP_073168671 555 LPLRKSHENPEIQKLYKDFLIEPLGEKSHHLLHTKYTK 592 Tangfeifania diversioriginum
WP_124991984 555 LPIRKSHENPEIVQIYKEFLDEPLSHKSHKLLHTSYVK 592 Labilibaculum euxinus
WP_079556276 555 KTIRKSHENPEVVKVYKEFLGEPLGHESHRLLHTHYTP 592 Alkalitalea saponilacus
WP_012635247 530 KKLRKSHENPYIKKLYQEFLDKHGSHKAHELLHTHYIN 567 Halothermothrix orenii
WP_013406264 530 KKLRKSHENPYIKKLYEEYLDKPGSELAHRLLHTEYIK 567 Halanaerobium hydrogeniformans
WP_006928134 531 EAVRASHQNPLIQELYDRYLERPLSHRSHELLHTKYTE 568 Caldithrix abyssi
WP_041356083 533 MKNRKSHENESLKKLYNEFLGEPNGHLSHELLHTTYVN 570 Melioribacter roseus
WP_073071554 535 STLRRSHENPDVQKLYAEFLEKPYSHIAHKLLHTYYTD 572 Thermosipho atlanticus
WP_014450900 531 SVIRRSHENPEIIQLYEEFVGEPNGHVAHHYLHTYYTD 568 Fervidobacterium pennivorans
WP_161848847 534 SKLRKSHENPAIQQLYVEFYKQPLSDLSKKLLHTHYTN 571 Athalassotoga saccharophila
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