1XMK


Conserved Protein Domain Family
z-alpha

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pfam02295: z-alpha 
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Adenosine deaminase z-alpha domain
This family consists of the N-terminus and thus the z-alpha domain of double-stranded RNA-specific adenosine deaminase (ADAR), an RNA- editing enzyme. The z-alpha domain is a Z-DNA binding domain, and binding of this region to B-DNA has been shown to be disfavoured by steric hindrance.
Statistics
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PSSM-Id: 280459
Aligned: 5 rows
Threshold Bit Score: 94.8804
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XMK_A    8 DMAEIKEKICDYLFNVS-DSSALNLAKNIGLTK-ARDINAVLIDMERQGDVYRQGTTPPIWHLTDKK 72   human
P55265  135 IYQDQEQRILKFLEELGeGKATTAHDLSGKLGTpKKEINRVLYSLAKKGKLQKEAGTPPLWKIAVST 201  human
P55266  137 ISQNPEQKVLNRLEELGeGKATTAYALARELRTpKKDINRILYSLERKGKLHRGVGKPPLWSLVPLS 203  Norway rat
P33863    7 DERSDAEIVCEAIKNIG-LEGVTAVQLTRQLNMeKREVNKALYDLQRSAMVYSSDDIPPRWFMTTEa 72   Variola virus human/India/Ind3/1967
Q6TVV0    1 MACECASLILELLRKSDdKLPAKQIAKELGIS--KHEANRQLYRMLELDDVCCEDGNPPRWFVECAp 65   Orf virus
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