Conserved Protein Domain Family
PSS

?
pfam03034: PSS 
Phosphatidyl serine synthase
Phosphatidyl serine synthase is also known as serine exchange enzyme. This family represents eukaryotic PSS I and II which are membrane bound proteins which catalyzes the replacement of the head group of a phospholipid (phosphotidylcholine or phosphotidylethanolamine) by L-serine.
Statistics
?
PSSM-Id: 460783
Aligned: 58 rows
Threshold Bit Score: 255.95
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_002141760                   97 PHPIFWRFLLGLSILYLSFLVFLLFQDVESILSALR-NIDFS-LDKSTVE---VNYTEGsCSLLdws----ngILYNVRq 167
WGS:AAFB:cds.EHI_009800A      102 PHPMFWKFIQGVGLCYLMLICFLLFQNVNDVRQWLK-NIDPK-LGVPLPE---REYAID-CRLYtpelpckwnNFKNVL- 174
CAX64387                       56 kisiltKILNYLILIYYVIIMFLHFFSTSEVRTILR-FLNKN-IEFHAVE---KSYMEN-CN-----------NLANISd 118
XP_004030343                   58 PNEAFWRGVLRFCLIYLCALVFLCFQNNIDVRSLFK-YLYPE-LGQPVPHs-mHTYDDN-CDL----------EFENILd 123
Q23DR8                         58 PNEAFWRGVLRFCLIYVCSLVFLSFQNTKDARNIFK-HLDPE-LGKQVSKd-yHTYDDN-CEL----------EWDNILd 123 Tetrahymena thermophila SB210...
ESS36008                      226 PHPGFWRVVHGMCVVHLIVMVVLLVVDEETGRHALE-LLFPEiAG-KREEifaGTLVVD-CRI----------NASTIHr 292
CBJ31973                      126 PHPGIWRIVHGVGMLYLFAVSVLLVHPKDEAQRLLA-IFIPDvKGYTLSR---FEAGSLeCEL----------SASAVIg 191
A0D008                         99 PHPLFWRLLQSWACVYMMSIVFLIYFTPEQLQQFLQqFIDPK-LGRPLPS---KSYAED-CRFYtpen--ehsKFYNLTs 171 Paramecium tetraurelia...
WGS:AAGF:cds.TTHERM_00190960A 125 PHPSLWRMLQALGMCWLTVVVFALFFNRDDIQTFLKsFVDPE-LGQPLQD---KNFSED-CDIYtpgn--pkgDFYNLTd 197
EGR34121                       51 PHPAIWRMLQALGICWLICVVFALFMNRDDLQYFLKkFVDEN-LGKPLPE---KNYAEN-CQIYtpdn--prgPFANVId 123
XP_002141760                  168 rL-DFFAFAHFFGWFVKTLILRDNFLLWFNSIFFECLELTFKHILPNFHECWWDHLILDIFGCNFLGIIAGNIFIRKIKL 246
WGS:AAFB:cds.EHI_009800A      175 -F-DEFVIYHFVGWWARCVICRDWKLTWFNSILFEFMELSFQHILPNFHECWWDHIILDVFGCNALGIWLGSKTLQYFEL 252
CAX64387                      119 kI-DWFVCAHLWGWFAKGMIIRNFFLLNINSVIFELIELRFQHILPNFYECWWDHIFLDVLSCNLIGIVASILFMKYFNI 197
XP_004030343                  124 nF-DHYFLIHLINWFFASLIVRDAYILHSWSILDELIELSAQHVLPHFRECWWDHVFLDVLLSNTTAIILGLYVVDFLGF 202
Q23DR8                        124 nF-DHYFQIHLINWFCATLIVRDPYILHTWSILDELIELSAQHILPHFRECWWDHVFHDVILSNTTAIVIGLLVCKLFKL 202 Tetrahymena thermophila SB210...
ESS36008                      293 qLtSVWFVSHVVGWLVKMVILRHWGFCLIYSLCFELGELSFHWLVPELCECWWDSIFIDALLSNVCGMFLGVLFMKLVNL 372
CBJ31973                      192 qLrEVWFLAHLVGWWCKMCLFRDWGVCWVLSVGFELLELSMGWLVPQFHECWWDSLIIDLLGANVLGMTLGLYTLRFLET 271
A0D008                        172 sF-DVFVPAHIFGWTVKMWILRDFKLAMIQQIAFEFMEITFRHWLPNFWECWWDHVILDIIVCNTGGIVVGYYTMKLFGM 250 Paramecium tetraurelia...
WGS:AAGF:cds.TTHERM_00190960A 198 kL-DVFFVAHFIGWMVKMFICRDFKLCMIQSILFEFLEITFRHWLPNFYECWWDSIIFDIILCNSGGIIAGWWLMQKFEM 276
EGR34121                      124 sI-DVFFTAHFIGWLVKMFICRDFLMCMIQSVLFEFLELSLKHWLPNFAECWWDSVFFDILICNTGGIVVGWYLMNKFQM 202
XP_002141760                  247 YQYNWhssyslgsfnklddTSMKsdisivgatskttknlsdftdntnflfsnlrskyrevgsssensifnnKKPKkdily 326
WGS:AAFB:cds.EHI_009800A      253 REYNF--------------SGVS------------------------------------------------PMQKkgkif 270
CAX64387                      198 ELYDWki---------------------------------------------------------------pDKIKpn-kk 213
XP_004030343                  203 EKYDW--------------LG--------------------------------------------------RKGK----- 213
Q23DR8                        203 QPYDW--------------LG--------------------------------------------------RKDS----- 213 Tetrahymena thermophila SB210...
ESS36008                      373 CQYDW--------------LGRY------------------------------------------------PQDQ----- 385
CBJ31973                      272 RTYDW--------------NSKE------------------------------------------------KSHElarsl 289
A0D008                        251 KEYKWsl---------------------------------------------------------------rKENRkdswf 267 Paramecium tetraurelia...
WGS:AAGF:cds.TTHERM_00190960A 277 KEYKWsls-------------------------------------------------------------eaGKKKkpywk 295
EGR34121                      203 KEYRWsl---------------------------------------------------------------qSKYKksftq 219
XP_002141760                  327 MVIdl-wSKF-GIYTWTEYKWPKTLsNMKG------FMTFLLLTIIVQLIDLNYFFIKAELLLPVSHWILALRTICVAIC 398
WGS:AAFB:cds.EHI_009800A      271 RVI----GQF-TPTSWTRYHWGMFT-HWKR------FIYVIILIIYFQLFDLNSFFLKAELWLKPSHYLNLIRLIVLALQ 338
CAX64387                      214 NIIfptiDKL----------------CRKVftnsstLLILIFLSFITNIIDLNVFFLKAEIQLHHVNLIVIARTFAIGFI 277
XP_004030343                  214 -------KNY--------KEWSIWQ-CHRR------FGALLVIFLVIICNFLCGFFLINSLWIPPKNWLNIYRLLVWFLL 271
Q23DR8                        214 -------KGF--------FDWKVWK-CHRR------FGGLLAIWFVIITNFLCGFFMINSLWIPPQNFLNLYRLLVWFLL 271 Tetrahymena thermophila SB210...
ESS36008                      386 NVS----MSL-TPFASEASDWSFYK-TPRH------LFMSIVLLMICLFSELNVFFLMAALDIPAAHYSNPLRTLYIALL 453
CBJ31973                      290 RLL----AKF-SPLGWSKWRWEAFS-SLKR------TAQVFSMVAATMLLELNAFLVMNALEIPNNSNFNYMRMTVIFLV 357
A0D008                        268 KNL----KRLcLSPQLDKIEWKVFS-SVKR------FLLVIWFLVFMNLCDLSFFFNKFVLQINTAHNVMKFRVFPLGFF 336 Paramecium tetraurelia...
WGS:AAGF:cds.TTHERM_00190960A 296 NVK----ELFiTP-NLEKHDWKVFS-SSLR------FASVIYYMIFMNLVDLSFFFNKFVLWIRPSHPVLSFRTFMIGFL 363
EGR34121                      220 NLK----EIFiTP-NLEKHEWKMFS-SLRR------FILVMWFGIFMNLVDLNFFFNKFVIRIEPSHYILSYRTFVIGFL 287
XP_002141760                  399 GAAATRELYEFVTntS-NNSDKV-----GIQCWVLIAIVFTESLLCWRF 441
WGS:AAFB:cds.EHI_009800A      339 APLVFRQCYQYVI--D-KNTKDI-----GSASWILGLTLLLEGILCFKW 379
CAX64387                      278 SGKACKEFYRFLK--EgMTPKR------AFYIFLEIIILSLEFLLAIRW 318
XP_004030343                  272 SNLAFKEIYTDIK--TwGTEERVknpisGKCRWITFFICFTETFISIKF 318
Q23DR8                        272 SNLAFKEIYVDID--TwGTKKRVenpisGKCRWITFFITFTEAFIALKF 318 Tetrahymena thermophila SB210
ESS36008                      454 GVAAAAEHYEFTT----KRRDRI-----GRNKWLLIIILFVEWLVCAKY 493
CBJ31973                      358 ALLACSEYYEYCS--N-PACNRL-----GQNAWLILAIMQVEILLWIKF 398
A0D008                        337 SIVAARDYYVYIS--D-ENVTRL-----GPNAWLMHAIVLGEWVLFFRN 377 Paramecium tetraurelia
WGS:AAGF:cds.TTHERM_00190960A 364 AIPATREYYEYIS--N-PQQKRL-----GGICWLTQAIVYSELLVFLKN 404
EGR34121                      288 SIPASREYYEYIS--N-DNLKRL-----GGTVWLMQAIIFSEIFLFFKN 328
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap