Conserved Protein Domain Family
Y_phosphatase3

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pfam13350: Y_phosphatase3 
Tyrosine phosphatase family
This family is closely related to the pfam00102 and pfam00782 families.
Statistics
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PSSM-Id: 463853
Aligned: 211 rows
Threshold Bit Score: 103.477
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6BSM6                334 KQIDGISNFRDIGAwkiqnptyrLPnyDNESHyyVKPHIAFRCANTAD-VTQMGLKELRK-LNVKVMFDFRSSIEinndg 411 Debary...
WP_022170722           12 LPMENAYNVRELGG---------YAt-KKGSI--TIHHQFLRSENLTD-ITEEDKTFLIE-YGLSGIIDLRSREE----- 72  Anaero...
Prjna32935:ECBG_01315   5 LPLKGTYNTRDLGG---------YAa-KDGA---TAWKRFLRSDSLAN-LHPEDIAFLQR-YQLTTIIDLRTTLE----- 64 
WP_013271311            7 YPMKGIANFRDLGG---------YF--CKGGV--TKWGVFFRSTSLHKaVK-EDLAIMEQ-VGISRILDLRYPQErk--- 68  Lacrim...
WP_013256183            7 WNLQGVANFRDLGG---------YPc-KNGGA--TRYGIFFRSTHLHH-ATEEDLKVLQK-AHIDTIIDLRYEEEre--- 69  Sedimi...
jcvi:HMPREF9243_0726    3 YPFNEICNFRDIGG---------CY--KESGEi-IPRGKFFRSSMLFG-VDEADLNWLKD-LNVQAIIDLRAPKEa---- 64 
XP_002553317          350 YSFSNVSNFRDIGG---------YKt-RDGYR--VKPKVLYRCANPSE-VTDKGIKFMKEqLHVTRIFDLRSTKEaaen- 415
XP_002495258          374 HSFSHVSNFRDLGG---------YEt-VFQKRr-VKSGCFYRCANICD-ITPQALKYLQTrLGVVKIFDLRAPDEaken- 440
Q6CPF1                356 YDFSQISNFRDVGG---------YVt-TSGKQ--VKPGIMYRCANPNE-ATPAALDYMKShLFINRVFDLRAVNEateg- 421 Kluyve...
Q752H2                397 HDFSRISNFRDLGG---------YMt-ASGRR--VRHGILYRCANPCD-VTPEALQYMKDvLQIAQVFDLRATAEaaea- 462 Eremot...
Q6BSM6                412 spqNLEKY-------GIKRIHAPVf-----sETDYSPEVI-AIRYTNLMTSWFTYVNVYEDILE---------------- 462 Debary...
WP_022170722           73 ---ALIYPnpfrgnnAVKYINCPLi-------------tDgILDLRAVKEVGFDPGEFYVKLVE---------------- 120 Anaero...
Prjna32935:ECBG_01315  65 ---IEKEP-------------TPVidgvenwPISLISETM-GDVTQLEQPLIFNMAELYIQMIE---------------- 111
WP_013271311           69 --eMPDVPv-----kGAEWLGISLlgti----------pveKLQVNDKEEDTRTLINMYRQIIA---------------- 115 Lacrim...
WP_013256183           70 -lsPDRIPe------GALYHHISLmgrv----------evkDINVNSSVVDTRTLHRMYRQILT---------------- 116 Sedimi...
jcvi:HMPREF9243_0726   65 --eKQPNP--------------------------------------------------YRNLLKayqninlsggqdvgrs 92 
XP_002553317          416 -----------gvisGIDVENLAFn-----qNVSAAPEEL-ARLYRGLLLSSYMFPEAYQVMMQ---------------- 462
XP_002495258          441 gllPNEEL----------VHSLPFn-----rGMSVSPEML-AEKHKGLLISSYSFPKGYMMILK---------------- 488
Q6CPF1                422 -----------giipNFEVENLSFn-----nNMTLSPEEM-AKHYQGMFLSSYNFPQAYEIVLE---------------- 468 Kluyve...
Q752H2                463 -----------gilsGIPVCSVPFn-----kNMSMSPEEV-ARHYQDIFISTHNIPAAYEGILE---------------- 509 Eremot...
Q6BSM6                463 ---------------NGT------SAFRQVFEFIRDev----pASsfVFHCTAGKDRTGVLSMLILLFLGVDKHTISKEY 517 Debary...
WP_022170722          121 ----------------YK------EMLYKIFHFILDni---dgCL--LFHCQAGKDRTGVLAMILMGLAGVSKEDIVANY 173 Anaero...
Prjna32935:ECBG_01315 112 ---------------DRK------EQIKQIMETMAAae----gCV--LFHCAAGKDRTGVIAMLLLQLADVAKADIIANY 164
WP_013271311          116 ---------------SSR------TEIRDSVKAMIDak----gPA--LFHCAAGKDRTGILAMLLLGAVGVSQEDIIADY 168 Lacrim...
WP_013256183          117 ---------------FGQ------EEIAKTLNILAN-------AGtaIYHCAAGKDRTGIISMFLLSIADVPKEDIIADY 168 Sedimi...
jcvi:HMPREF9243_0726   93 aqlakesddpyfmaiRYLeycdnySAIKGVFDQLLSnkak---gwgtVIHCSAGKDRTGVITYLIYKAAGLPLVDIVADY 169
XP_002553317          463 ---------------NSI------PQIRRFCRYIINeecdelhAA--VFHCAAGKDRTGILAVLILGLLGVDDDTIAHDY 519
XP_002495258          489 ---------------NSI------DEIRIFFQFLLNmts--geAV--VFHCTAGKDRTGILGMLLLLILGVDEDTISREY 543
Q6CPF1                469 ---------------NSL------PVIRRFFEYILEgnvdekhAI--VFHCSAGKDRTGILGMLILGLAGVDADTISHDY 525 Kluyve...
Q752H2                510 ---------------NSV------ESIGRFFRAIVDgtvgrgrAA--IFHCAVGKDRTGILAMLVLGLLGVDADTIAHEY 566 Eremot...
Q6BSM6                518 ELTTVGLK------NDHASIRDKFIKTmENFKtkmenvedvaqii------aqgrkgwtieedgFQNLISSRYEAMLATI 585 Debary...
WP_022170722          174 EVTHTYLK---------ENVKLRLEDG-------------------------------------LEELEFSKPQWIEKAY 207 Anaero...
Prjna32935:ECBG_01315 165 QTTHTYLAanplvaQQVQTI--------------------------------------------TNEMWLSAPEYLLPVL 200
WP_013271311          169 EISHHYir------------------------------------------------------sfTSDISGSHGSNMYKLL 194 Lacrim...
WP_013256183          169 EVSHSYir------------------------------------------------------dfTSDISGSNYYNMQLVL 194 Sedimi...
jcvi:HMPREF9243_0726  170 QVSYAYIK------HDPRIIKEGH----------------------------------------IQNVNRSYPEIMENFD 203
XP_002553317          520 EMTSLGLQ------TE------------KRLKkamedrgdryyemlg--skdlardyqatpmsmCKNLLSSKYEAMRLFL 579
XP_002495258          544 ELTTLGLK------TE------------TKLIkkleargdlyysmlgsnseelvkqykltpkkmCQNLLSSRYESMRFFI 605
Q6CPF1                526 ELTKLGLT------TEKRLIqritgrgdkfytilgp------------hgheiasawgvspkemAANVLSSKYEAMRLFI 587 Kluyve...
Q752H2                567 ELTTIGIT------TE------------KKIYdllaassskfydimgpagrtiareyqltqtkiRDNILASPYEAMRVFI 628 Eremot...
Q6BSM6                586 ELFNQKYGSIVNYMKTQLKFEDSDLLKIYENLVY 619 Debaryomyces hansenii
WP_022170722          208 DHIIEHYGSFKVYL-MAVGLTKKEIKKIKGKLAG 240 Anaerobutyricum hallii
Prjna32935:ECBG_01315 201 THLEETYTDAYHYL-RTIGVAQETLVHLQSKLID 233
WP_013271311          195 NEISEQWGSVAGFL-MECGISMDELSLLIEKFVM 227 Lacrimispora saccharolytica
WP_013256183          195 EFLEKRYGGAVPYL-KAIGIDETTLHTIRSKFIL 227 Sediminispirochaeta smaragdinae
jcvi:HMPREF9243_0726  204 RDFMAKYTSIENYFR-HLGYQDQEIEAIKNLLY- 235
XP_002553317          580 DHFRSVYGSFDSFYSSVVKLSGSEIKKLKEALLE 613
XP_002495258          606 DDFFEEYKSIDNFFLYELEFTTQDIGKLRDFYLE 639
Q6CPF1                588 DAFLLKFGSFELFFLEQLKFTEKEVEKIKIELTI 621 Kluyveromyces lactis
Q752H2                629 DRFLAIHGSFSAYFESKLGLQPEDIKLIRHQLLE 662 Eremothecium gossypii
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