3HPA,2PAJ


Conserved Protein Domain Family
SsnA

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COG0402: SsnA 
Cytosine/adenosine deaminase or related metal-dependent hydrolase [Nucleotide transport and metabolism, General function prediction only]
Cytosine/adenosine deaminase or related metal-dependent hydrolase is part of the Pathway/BioSystem: Pyrimidine salvage
Statistics
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PSSM-Id: 440171
Aligned: 641 rows
Threshold Bit Score: 55.9882
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3HPA_A        30 Tl-----------------LVKHAdVLvTM--D-----D-----TrRELRDAGLYI-EDNRIVAVGPS-A-ELPeTADEV 77 
WP_014430008   3 Avnr-------------efWAPRAwV------------Gg------RWREQVRLAAgADGCWAAIDCGvA-PPP-GAER- 48 
WP_058720518   3 Aal---------------yWAAWAwV------------Eg------RWQADVLLSVgADGHWQDIRVGqA-QPA-DAMR- 46 
WP_058936252   4 Ttl---------------fHAPLAwL------------Dg------RWQPDVLLRVgADGHWLDVRAGlP-APE-GARR- 47 
WP_004863646   1 --------mhipsphtplaGVSNArLP-----AwalpaGwptehNgTPLT-ADLTF-ADGQIATIAPS-G-Q---ANHGL 60 
WP_012373974   3 VrektlpvepapaatqpahDKEIGwLP-DCvyT-----Gd------KFETGLAFFAdATGRITRFTREsA-DLS-RAKR- 67 
WP_011045082   2 Kl-----------------YAENIlL------------Nd------GWASKQTITI-EQGIITAVDAG---KIE-GAEI- 40 
YP_426390      3 Nl-----------------FFQSLlL------------Pe------GWAENVAMTVdENGMIATLSPG-SpPPA-SGPS- 44 
WP_075793390   3 Al-----------------FARHAlL------------Ae------GWQRDVLLEWdVRGDLTKAAPD-A-SPP-LGVA- 43 
WP_082990328  47 Ti-----------------FARKAlL------------Pe------GWRANVRLQI-AAGRIVAASPD-N-RHA-EDDV- 86 
3HPA_A        78 LDLRGHLVIPGLVNTHHHMYQSLTRAvpaAq----------NaELFGWLTNL-YKIWAHLTPEMIEVSTLTAMAELLQSG 146
WP_014430008  49 --LAG-DALPALVDAHSHAFQRAFVGl--Serrd----dahD-DFWSWR-DRmYGVALKLKPEQLRAIAAHLYAELLAGG 117
WP_058720518  47 --LSG-PVLPSLVDTHSHAFQRAFAGl--Aerre----agdD-DFWSWR-DRmYGLALKLSPAQLRAVAAQLYQELLAGG 115
WP_058936252  48 --LDG-PVLPSLVNAHSHAFQRAFAGl--Aeqra----rdsD-DFWSWR-ERmYGVALRITPDQLRAIAAQLYTELLAGG 116
WP_004863646  61 WDLGGALTLPGLVEPHAHLDKTYTIEr-cRps--------eP-GLLAAIRAMh-EDRRHWTAQDLQRRASAALARAAANG 129
WP_012373974  68 --LPGQAALPGMVNTHAQSWQRVLRGr--Felrl---rsdrE-TLGDWT-ERlALALGRLTADDLYDAARLAFLEMLATG 138
WP_011045082  41 --AKG-AVIPGMVNCHSHAFQRAFAGf--Seqgs----egqD-SFWTWR-KImYQFLAQLTELDAKNIAKQLYIEMLKMG 109
YP_426390     45 --FRG-PAFAGIPNLHSHAHQRALAGs--Gersg---gdgeD-SFWSWR-KAmYAALARLTPEAFEDVATQLYVEMVKAG 114
WP_075793390  44 --RVD-YVLPGMINLHSHAFQRVIGGl--TeraesgpdrspD-SFWTWR-DLmYRVANRITPEQMEAVAAQLYAECLRHG 116
WP_082990328  87 --DAD-IVIPGLCNAHSHAFQRALAGh--Teqra---pahrD-NFWTWR-ERmYRLSALIDAPRLMAIARQAYTEMVSSG 156
3HPA_A       147 CTTSSDHLYIYPn------------------gSR----LDDSIGAAQRIG-MRF-HASRGAMSVGqrdgglP---PDS-V 198
WP_014430008 118 YSQVCEFHYLHHdldgsa---------yadpaAM----SHALADAAQDAG-IGL-TLLPVLYERAg-----FqaeALR-P 176
WP_058720518 116 YTQVCEFHYLQHapdgra---------ysdelAM----SWALADAAAEVG-IGL-TLLPVLYARSg-----FgqpGLR-E 174
WP_058936252 117 YTQVCEFHYLHHredgqp---------ydddlAM----SWALAEAARDVG-IGL-TLLPVLYAHAg-----FaetGLR-D 175
WP_004863646 130 VTHLRTHIDWFT--------------------AAapdaWQEIARLDH--PgISVeRVA---L-------------VPLgL 171
WP_012373974 139 ITCVGEAHTLQRaadgap---------wpephLG----ARAILRAARDVG-VRI-CLLNGFSNRAd-----Fg-qPAG-S 196
WP_011045082 110 YTRVAEFHYLHHdidgstynssvttdksaslaTM----AQAIFDAAKESG-IGL-TLLPVLYQHSg-----FgeqTPS-D 177
YP_426390    115 YTAVAEFHYLHHdrdgrp---------fadpaEM----SHRLVAAARTAG-IAL-TLLPVLYSASg-----FdgaPPT-E 173
WP_075793390 117 YTAVCEFHYVQRapgghv---------ygqpaET----AQRIAQAAHESG-IGV-TLLPVMYAYAg-----FndtPLR-Q 175
WP_082990328 157 YTSVCEFHYLHAaves------------naddRM----YDALLEAARDSG-IRL-IYVPVLYERGg-----FdnePLS-P 212
3HPA_A       199 V-----E-REPDILRD--TQRLIETYHDEgryAMLRV-----VVA--PC-SPFSVSRDLMRDAAV--LAREYGVSLHTHL 260
WP_014430008 177 DqrrfaT-TPRQVREI--ADALRg-------rPGVTV-----GAA--VH-SLRAARPASIAELAA-----ACDGPLHVHV 233
WP_058720518 175 DqrrfkT-DAAWVWAA--SQRINA--Ar---rPLLNA-----GVA--LH-SLRAANADDIQALQA--LVGEADIPIHIHI 236
WP_058936252 176 TqrrfrT-DADWVWRA--CQRINA--Ag---lPLVSA-----GVA--LH-SLRAAHPEDIRHLQQ--RVGTTPVPIHIHV 237
WP_004863646 172 -------------FAdpaAAEAIAQt--------VAEggegcLLGgfVHsSn--WDPAAMENLLR--SATRWRLDLDLHI 226
WP_012373974 197 GparglTpTAEQFLQE--SDSLRAHIEKNlpgDEAWL-----GVT--VR-GLGTAPLEMMKTVAA--YAHAKRLRLHVVL 264
WP_011045082 178 GqkrfiN-STEQFNQL--VSDCFTLSEq---ySNTNV-----GIA--PH-SLRAVDKTSLLSAVKhvRSLDNQAPIHIHI 243
YP_426390    174 GqkrfhT-TGSSFGAL--VERLKRDYGr---dGAIML-----GIA--PH-SLRAVPAPLLAEVIG----AHPEGPIHLHI 235
WP_075793390 176 DqerfrT-DPAQVLRI--VEALEPLRG-----PQLEV-----GAA--PH-SLRAVSAAQLRELAQ---ALPAGRPLHIHI 236
WP_082990328 213 PqqrfhR-ELPEFLHH--YRRCRERAG-----SDATV-----GIG--AH-SLRAVSAESLQEIAA--VAGSDNVPMHLHI 274
3HPA_A       261 AENVNDIAYSREKFgMTPAEYAEDLGWVGHDVWHAHCVQL-------DDAGIGLFARTGTGVAHCPCSNMRL-A------ 326
WP_014430008 234 AEQTAEVDDCLAATgCRPIEWLARHAGLDARWQLVHATHA-------TPAEIAAVAASGAGVVICPATEADL-G------ 299
WP_058720518 237 SEQQQEVRDCLAATgQRPMQWLCSQFKPDARWHLVHATHS-------TRDEIAQVAASGASVVICPGTEGNL-G------ 302
WP_058936252 238 AEQQQEVRDCLAATgQRPLAALADYG-LDPRWQLVHATHS-------TRGEIDRIAASGAGVVICPGTEANL-G------ 302
WP_004863646 227 DEELSDNPRGLAWL----AEYLSRHA-FPGRLCCSHGCALacgseeqAEKILRQLAAHSVTLIALPMTNLLLqDavtgrt 301
WP_012373974 265 GASAHEAAACVAEYgRTPAVLLGEHGLLDKRFVAVHGVHL-------SAEDVRAIGAARVTVCACPAAAAQL-G------ 330
WP_011045082 244 SEQQKEVDDCLAHFgQRPVQWLLDNVELDKHWCLIHATHI-------DEAERKGIIAKEAIAGICPTTEANL-G------ 309
YP_426390    236 AEQTIEVTDCLAHTgQRPVEWLLDHVDLDPRWCLIHATHV-------TDQELAGIAASRAVVGLCPTTEANL-G------ 301
WP_075793390 237 AEQQLEVAQCVEATgMRPVDYLMQQVGVDARWCLVHATHL-------SDGERDRLAASGAVAGLCPTTEANL-G------ 302
WP_082990328 275 AEQQREVEQSLAIRhRRPVRWLLEQHALSSNWCLVHATHV-------DADEVAALAESGAVVCLCPSTEANL-G------ 340
3HPA_A       327 ---SGIAPVKKMRLAGVPVGLGVDGSASn----DGAQMVAEVRQALLLQRV-GfgpDAMTA-R-------EALEIATLGG 390
WP_014430008 300 ---DGLCDLPRWLDAGVPLAVGSD---Sq----VVRAWPEELRWLEWGQRLlHrrrNVSAApGvepssaaGLFERVRAGG 369
WP_058720518 303 ---DGLIDLPGWLAAEVPISIGSD---Sh----VTRNWVEELRWLEYGQRLgLqqrNVAAApGrqpstaaRLFEAARQGS 372
WP_058936252 303 ---DGLADLEGWLAAGVPMTVGSD---Sq----VTRFWVEELRWLEYGQRLgQqrrNVAAWpGrqpstaaRLFDACLKGS 372
WP_004863646 302 prqRGITLLQEARCAGVATLLGCDNVQDafcpaGSYDPLDTLACGLFSAQLs----DVFD----------RQSQLICDRA 367
WP_012373974 331 ---EGSLAADQLLATGATFALGTD---Gp----LQSSVLDQARAIELLLRs----qSARAV-GlrgdlaaALWQMATSAG 395
WP_011045082 310 ---DGIFPTTEFLADKGTIAIGSD---Sh----ISVNPIEELRWLEYAQRLiKqqrAILAT-DeqasvgqNLWQQAAIGG 378
YP_426390    302 ---DGLFPADRFLGLGGRFGIGSD---Sh----ISVNPVEELRWLEYGQRLtTrrrTVLAG-GidrstgrALIEQAQISG 370
WP_075793390 303 ---DGLFPLAPYIAAGGRFGIGSD---Sh----VSQSPVEELRWLEYGQRLaLqrrNIAVH-GderdvagFLWRQALLGG 371
WP_082990328 341 ---DGLFPLAAYLQQGGRLAIGSD---Sh----ISINPFEELRWLEYGQRLvAeqrNVAAI-Gqcn-tgsALFERAAQGG 408
3HPA_A       391 AKVLNRDDIGALKPGMAADFAAFDLRQPLFAGaL--HDPVAALVFC-A-PSQTAYTVVNGKVVVRE 452
WP_014430008 370 GTAAGFT-HWGLEVGARADLVELDPAEPALAG-LppSHRLDGLVFG-ApAAPFKRTLVAGRWAAAD 432
WP_058720518 373 AAPAGFK-QWGLLPGARADFLVLDTAASGLAG-LppASLLDGLLFA-SqGQVLREVYVAGHLRLQP 435
WP_058936252 373 AAAAGLG-AWGLVPGARADFLVLDVAGCGLSG-LpaDALMDGLIFA-SqGQPWREVFVAG---VSQ 432
WP_004863646 368 ALTGAPADAAPFAVGNAASVVIFPGSD--------------R--FTwPlNSAARLVINRGRLTHQR 417
WP_012373974 396 ARSLGAP-GGALEVGRPADFFTVNLFDPALVG-AapEQLLAAMVFG-VsPRAVREVWVGARQRIGQ 458
WP_011045082 379 AQSTNSN-TGSLAIGKQADLLVLDKDKTKLFA-SasQQLLDSMIFA-SqQNPVSDVMVNGVWQIKA 441
YP_426390    371 ATACAIK-AGRLAVGQRADIVVLDGEAPVLCG-RsgDGALDAWIFS-GnAPTVHSVVVGGALVVEN 433
WP_075793390 372 AQAAGRR-LGVLTPGRRADLLVLDSAHPNLDG-VppHEVLGRFLFS-GnDNLVRDVLAGGHWVVQG 434
WP_082990328 409 ALAAGTD-GGRIEAGCVADLLLLDGADPMLAG-HdaDTVLDALVFS-GyALPLDRVMVNGAWQVLE 471
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