5N7W


Conserved Protein Domain Family
IL17

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pfam06083: IL17 
Interleukin-17
IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.
Statistics
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PSSM-Id: 461823
Aligned: 83 rows
Threshold Bit Score: 55.7365
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5N7W_X        69 RSTSPWNLH-RN-EDPERYPSVIWEAKCRHLGci----nADGNvdYHMNSVPIQQEILV--------LRR--EPP-HCPN 131
XP_002594253  94 RAYCPWQVI-VD-SNPNRFPTDIAYARCQSTFp-----sQDGEynWTMACDSVTYTKPV--------LVReeCSGaDNTY 158
AIR74621      53 QSICPWSTI-MV-EDNDRVPRQLPSTTCTKSSvv---fqLNGTp-VEYACELVEVTVSV--------LKY------HPSG 112
EFX60048     148 SQL-------VAvKRQDRFPNVRLFAKCLCRKclg--ntITSYpySSSTCLPVKVLMPV--------LIRshSSGqQSDA 210
XP_002604638  94 RSMCKWRYE-DN-VDPNRFPSTLKVAV-KEYTgsrcrdpATGAprADLACLPIDYELNV--------LRK------NSEG 156
XP_002604659 169 RSVCPWRYD-DD-FKANRFPHTLRVAV-KTHTgsrcidpATGAprRDLRCLPVEYKLNV--------LRK------DSEE 231
EFX83770      94 RSLCPFDIQ-RD-VNPLRIPDVIHRAHCLCESspc-sagQQSQsqQPARCLSLVSPLKVayldpqlkLVV---------- 160
EKC38792      43 VDSCPYHYQ-LN-YDRFRIPQSIIQVKCNCDNcigrkpdGSLQelHDGRCTEVMIPRQV--------LRL---CRkKRRK 109
EKC26195      80 TSICP-TYRvTD-VDVNRIPQTIVQRRCKCTEclsvldsTLGPr-AFSRCVPTFQYQMV--------LRR--VGCaSGVF 146
XP_002606350 346 RSVCPWSYY-ID-HDPNRVPHDIAQAKCRCTAcl---dpVTKKqnYNYACVPVTIQKLV--------YRR--KKKkSGGY 410
5N7W_X       132 SFRLE--KILVSVGCTCV 147
XP_002594253 159 RYKCV--HLTVPNACVAV 174
AIR74621     113 YWERS--DELVPVACTAV 128
EFX60048     211 EWKFF--LEPVSVSCVCG 226
XP_002604638 157 EWQES--YEFVTIGFTCA 172
XP_002604659 232 VWQISadPEFVTVGYTCA 249
EFX83770     161 --ATE--VIHVPVACICA 174
EKC38792     110 VYTVR--IEEYAVACTCQ 125
EKC26195     147 EYKPV--MEPFVVGCSCK 162
XP_002606350 411 RYREE--WQGVTVGCTCV 426
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