2CG8,1B9L,2O90,1NBU


Conserved Protein Domain Family
FolB

?
pfam02152: FolB 
Dihydroneopterin aldolase
This enzyme EC:4.1.2.25 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate.
Statistics
?
PSSM-Id: 460466
Aligned: 791 rows
Threshold Bit Score: 43.6016
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2CG8_C              4 LQIKDLEMFAYHGLFPSEKELGQKFIVSAILSYDMTkaaTDLDLTASVHYGELCQQWTTWFQ-EtSEDLIETVAYKLVER 82  Streptococ...
jcvi:FSU_0798       6 IRLKDVQFDCIVGILPYERENEQPIILNLTLWLDFAkaaETEDLNESIDYAKLAEELKGFIRlS-CFKLVETLVVKTAEY 84 
MPITM:COCOR_07450  23 MELRGLTVDVIVGLYNRERVTPQPLRLDVALFLDARqaaVGGRLANTVHYGRLAGELRFLLD-AcRFELLESAAEAVCRY 101
WP_013375077       21 IELRNLAMDCIVGVYPRERIVAQPLRLDVALFLDTReapGAGHLTHSMHLGRLEGELRFLLD-AcRFKVLESAAEAVARY 99  Stigmatell...
jgi:Asuc_1884       5 IFIEGLTVFAQIGVYDWEQQIKQPLVFDLEMTWDSRkaaETDNVANCLNYAEVSDFVVSYVQsK-PFLLIERVANEVAEQ 83 
P46362              4 VFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKqaaETDDVVYCLNYAEVSQAIIDYVEsK-PFLLIERVAYEVADL 82  Haemophilu...
Q7VMJ7             10 VFIHELTAFAAIGAYDWEHTIKQRLVFNIEMAWDFTqavMTEDLQYCLNYAEISEKILHFVEsK-PFKLVETVAHQVADF 88  [Haemophil...
USMARC:WQG_2010     5 VFIHELTAFASIGAYEWEHTIKQRLVFNIEMEWDFSkavAEDNVEFCLNYAEVSQKILDFVEnT-PFKLVETVAHRVADL 83 
ACQ67221            4 LFIEALRIFTLIGVHDWEKTLRQELIFDIKMGYENRkpaSSDQVEDCLNYVDICDSVQQHVTrQ-RFELIERVAEEVADL 82 
tigr:BCI_0620       4 IFIKKLIVMAFIGVYDWEQQRLQKLIFDIEVGWNNVtaaLSDNINDSISYTAISEAVLSWVHgK-HFALIERVAEEVAEL 82 
2CG8_C             83 TFESyPl------VQEMKLELKKPWApVhLS-LDTCSVTIH 116 Streptococcus pneumoniae
jcvi:FSU_0798      85 VLEHyPk------ATAVEVSVAKPQA-VpGClGAEASVKIS 118
MPITM:COCOR_07450 102 LLAPpTdaaphapLHAATVRVTKPEAl---TgWAIPSLQVH 139
WP_013375077      100 VLLPpSadaphvpVRAVTVRVTKPNAl---AgHAMPSLQVH 137 Stigmatella aurantiaca
jgi:Asuc_1884      84 LRQKfN-------ISWLRLKLSKPKA-VsQA--RNVGIIIE 114
P46362             83 LESRyQ-------LQGLKIKLSKPKA-VaQA--RNVGVLIV 113 Haemophilus influenzae Rd KW20
Q7VMJ7             89 LQENyA-------IQALRIELHKPKA-VaQA--SSVGVIVE 119 [Haemophilus] ducreyi
USMARC:WQG_2010    84 LQREfA-------IQRLRIELHKPKA-VaQA--ESVGVIVV 114
ACQ67221           83 LLQRfS-------SPWVWIKVSKPRA-VsSA--GNVGVIIE 113
tigr:BCI_0620      83 LINKfS-------LTWVRIKIQKPSA-VpYA--KSVGVIIQ 113
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap