Conserved Protein Domain Family
Solute_trans_a

?
pfam03619: Solute_trans_a 
Organic solute transporter Ostalpha
This family is a transmembrane organic solute transport protein. In vertebrates these proteins form a complex with Ostbeta, and function as bile transporters. In plants they may transport brassinosteroid-like compounds and act as regulators of cell death.
Statistics
?
PSSM-Id: 460991
Aligned: 263 rows
Threshold Bit Score: 96.4214
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_002142791   4 YILIANLSTLFTLLISVYNIGQQYTHLQRPKFQLYICRILSMIPVYAILSHISFISPSHAVILNIIRDCYEAYVLFSFLK 83 
XP_005998521  36 LFAVLTIMTAVALLVYVEEVVYIYKKIPTS-KRSIVMWVNATAPAIASTSCIGMWIPRATVFTDYTTAIFFSIVVHKFLV 114
XP_012963878  36 LFAILTLMTLIADLVFIEEVIYIYRKIPSS-KRSLLIWVNAAAPVIATTSCIGMWIPRSTMFTDFTAAVFFAIVIHKFLM 114
XP_002590087  26 LYGTAGGFTLIVLLLFLEETVFFWRRYSNAPRRTKILLILSIYPVIAVTCMTTLLAPRTTLINEFALNIALAVGVYQLPL 105
XP_001845253  43 IIGITIALSLVTFVICGKNISQVLRHTPKRFKTKTII-LLSIYPTVTALAMVSVLVPKSYFVCDTVSHIYFMICAYIFYS 121
XP_011053482  38 LLSVGSIILVLTIYFFASACRNILSQKDSEFYKTNAIIILSIYPITSVCSLMAIAIPRGQLLSEAITQIFLMISLYRLYL 117
XP_001949206 103 IFTVGAVIVAMIFYLYVDTLRCII-KNAPPMVKTHSAFILSVYPVVAVATYCAILVPRAHLLAEAMTQGMFMASMYQLFC 181
EFX65694      31 STITFGVTTLILVALFIANV-AGFIRHSPPHRRLLLCWVTSFPMIISFLALMTLLIPRAGNLCDTVKQIFMPFTMMHFVD 109
EFX76235      33 FSVFGIVSTLMVTAIFVLSI-FHVVKKSTPQWRRLLTWIVSMPMIVSILSLITFIVPGAAILCETVKQSYLPFVLMHFID 111
EFX65693      34 VGIAGTISTILLIILFIVNV-FTNIKKSPARRRRLLCWITSMPMVVSILSLIIFLVPRAGDVCDIVKQIYLPFVLMHFVD 112
XP_002142791  84 LLIYFLDGd-nAV-----------------------------------IKsleergylvnifphhhifylinildytseh 127
XP_005998521 115 MMIKECGGqkaFLkrfqnerfklytgpfc----ccclclpsasmtrrtLF------------------------------ 160
XP_012963878 115 MMIKECGGqkmFLrrfengrfkistgpcc----ccclclpgvritrqtLF------------------------------ 160
XP_002590087 106 LVTDYMGGaarMVktlsaipvalnmppc-----cccvciprktltrrlLR------------------------------ 150
XP_001845253 122 LVMAYVGGedgFIkssdtetfnvrtppcc----ccvpflkrspvtknsLL------------------------------ 167
XP_011053482 118 LLLD--------VgrrkisetpalmlrvgpcccwpclpfpnlqmtdanLS------------------------------ 159
XP_001949206 182 LFMAYCGGeanLIasvkpqsldmqvppccc--wpcccflpkftltkkhLR------------------------------ 229
EFX65694     110 LTLNFKGGqsaALedllqsntpmslclppc--ccvglcvrqldytkkrLR------------------------------ 157
EFX76235     112 LSLLMEGGhrdTIqdltnkdipinfcrpp--------------------------------------------------- 140
EFX65693     113 LVLLIQGGeegVLndvvevhaplslchppc--cffgiclrhltftkirLR------------------------------ 160
XP_002142791 128 lpdytykkqinklcngnnhccrenkntliskcndvipccnccryykevirfytFIKLGVLQFVIIKPTVALSALYLESIG 207
XP_005998521 161 -----------------------------------------------------ILKLGTFQFTFLRPILIFILIVLWSDQ 187
XP_012963878 161 -----------------------------------------------------WLKLGTFQFAFFRPVFMFLSIVLWTNG 187
XP_002590087 151 -----------------------------------------------------KMKLLVLQGVFVRPLFTYISAVMYTDD 177
XP_001845253 168 -----------------------------------------------------FTRLLILQLPIIQSILFFGLNIVFLED 194
XP_011053482 160 -----------------------------------------------------WIGILALQLPITQSLLYFILLYIEAED 186
XP_001949206 230 -----------------------------------------------------HLRMLVLQLPVVQGFVYMVLLVMWAEE 256
EFX65694     158 -----------------------------------------------------VLKSLVYQMPLVQLAIIVLIVLLTEAE 184
EFX76235     141 --------------------------------------wcciglcyknitynkYKHGLVYQTPLFQLVINLIMAILESAG 182
EFX65693     161 -----------------------------------------------------IVKGLVYQAPVFQFVLIVIMNVLDHAE 187
XP_002142791 208 KYgags-fslDTGFPYLA--FLNGVSVSLTIYSLFLLYISVYE--KLR-PMKPILKFLCIKLIVFVNSWQSLIISLLSTV 281
XP_005998521 188 GFqga--gpeGSAALLINilVG--ISTITALYPVSIMFTQVRL--ILA-SQGIVPKFVLYQFIVILSQLQTFIISTVASN 260
XP_012963878 188 NYslsd-lspEGAAIWIScfVA--ILTIIALWPVGIMFQQVRG--LLN-CKKIIPKFALYQFVLILNHLQTAIINILAMQ 261
XP_002590087 178 RHtp----gmASSPIFVLcaVALVLSFLCALSGLVFFVRAADP--YMP-QAMLKGKLVCVLLPLVLVTVQKNIIVALSSA 250
XP_001845253 195 LDnf------nrIILYFVpfIA--GSILLGVWGLNILVRMIAP--LYE-EFKIMGKYVVLQAVLILCKIQPVVIMVIVTY 263
XP_011053482 187 PMlt------tqYVTFLQpvVV--ISILLGIYSLTITTKTLHT--AVP-EVKLYYKTLVLQLVLLFSKLQTGIIKALPAA 255
XP_001949206 257 ESly------qvNYMYMQpfIV--ISIICGMWGISMTMRVLGD--ILK-DHSIQGKFVVLQLVLVLAKLQGLAFRGVVWA 325
EFX65694     185 VIrrdkgpdgVFLFLNVLniVC----FCLAMWAFNIITRSFAP--QLT-AINFLYKAQLVGLGIMLMKLQNFVLVILSVS 257
EFX76235     183 VLervi-rnvAFAVLGVTniIF----FTIGMYGYNVLTTGFAQ---LSeWKNYPLKARVLFLCVVLLKVQTLILLLLGVG 254
EFX65693     188 FMeknk-sdrLYQFFAALniLA----FMFGIWGFNILNGALSQllRTK-WKRYILRTKVLSAFVVILKIQNFILGILFFY 261
XP_002142791 282 NILPL------EPIKALFINNWLLTLEMSIFAIIYGFAF--SYKDF 319
XP_005998521 261 GHIVCapp-lsGKARASYMSQQLLIMEMFIITILSRFYYrrRYEDV 305
XP_012963878 262 QIIPCapp-fsSSARGAYITHQVLIMEMFLITLLSRVVYrrKYDEL 306
XP_002590087 251 GIAVCtap-ftSVSRGNILYAYVLIVEMFLLSFLARALYrrPDLPF 295
XP_001845253 264 VTPRCdfp-lvLQVQKNAVFQLCLCGEMVFLSLWAFQLY---KTPS 305
XP_011053482 256 GVFPCkpp-itPAIYANVMCNALMLVEMMMLCYAAWYVYyvDLEKN 300
XP_001949206 326 GWLPCkpp-isPTVYANLIYNSTMLWEMLVLAALARKLY---KKPL 367
EFX65694     258 GVVPCiapvtsRIVLQKTIDASLTLFEAFILGILTFIEYrkLDRQN 303
EFX76235     255 GSIPCiepyisPVVMRKSIEAALCLVEALIFAVIFFPVFrvVDNGV 300
EFX65693     262 NVIPCivpyvsPAIMRKTIDAALSLLEALIFGVLFYLVYqvRDITE 307
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap