Conserved Protein Domain Family
PTZ00265

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PTZ00265: PTZ00265 
multidrug resistance protein (mdr1); Provisional
Statistics
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PSSM-Id: 240339
Aligned: 3 rows
Threshold Bit Score: 2635.87
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
156095386    1 MKKDQRQPRDnsnssNNLSIKDEVEKELNKKGTFELYKKIKTQKIPFFLPFKCLPSSHRKLLGVSFVCATISGGTLPFFV 80  
124506379    1 MGKEQKEKKD-----GNLSIKEEVEKELNKKSTAELFRKIKNEKISFFLPFKCLPAQHRKLLFISFVCAVLSGGTLPFFI 75  
221056887    1 MKKDQRQSIDnnsggSNLSIKDEVEKELNKKGTFELYKKIKTQRIPFFLPFKCLPPSHKKLLGVSFVCATISGGSLPFFV 80  
156095386   81 SVFGVIMKNMNLGENVNDIIFSLVLIGIFQFILSFISSFCMDVVTTKILKTLKIEFLKSVFYQDGQFHDNNPGSKLTSDL 160 
124506379   76 SVFGVILKNMNLGDDINPIILSLVSIGLVQFILSMISSYCMDVITSKILKTLKLEYLRSVFYQDGQFHDNNPGSKLRSDL 155 
221056887   81 SVFGVIMKNMNLGENVDDIIFSLVLIGIFQFVMSFISSFCMDIVTTKILKTLKVEFLKSVFYQDGQFHDNNPGSKLTSDL 160 
156095386  161 DFYLEQVNAGIGTKFITIFTYASAFLGLYIWSLFKNARLTLCITCVFPLIYICGVICNKKVKINKKTSLLYNNNTMSIIE 240 
124506379  156 DFYLEQVSSGIGTKFITIFTYASSFLGLYIWSLIKNARLTLCITCVFPLIYVCGVICNKKVKLNKKTSLLYNNNTMSIIE 235 
221056887  161 DFYLEQVNAGIGTKFLTIFTYTSAFLGLYFWSLFKNARLTLCVTCVFPLIYICGVICNKKAKINKKTSLLYNNNTMSIIE 240 
156095386  241 EALVGIRTVVSYCGENTILKKFNLSEKLYSKYTLKANLMESLHIGMINGFILASYAFGFWYGTRIIISDLSNQQPNNDFH 320 
124506379  236 EALMGIRTVASYCGEKTILNKFNLSETFYSKYILKANFVEALHIGLINGLILVSYAFGFWYGTRIIINSATNQYPNNDFN 315 
221056887  241 EALVGIRTVVSYCGEHTILKKFNLSEKLYSKYMLKANFMESLHIGMINGFILASYAFGFWYGTRIIISDLSNAQSNNDFH 320 
156095386  321 GGSVISILLGVLISMFMLTIILPNITEYMKSLEATNNLYEIINRKPLVENNQDGKKLKDIKKIQFKNVRFHYDTRKDVEI 400 
124506379  316 GASVISILLGVLISMFMLTIILPNITEYMKALEATNSLYEIINRKPLVENNDDGETLPNIKKIEFKNVRFHYDTRKDVEI 395 
221056887  321 GGSVISILLGVLISMFMLTIVLPNITEYMKSLEATNSLYEIINRKPLVENNNDGKKLKDIKKIQFKNVRFHYDTRKDVEI 400 
156095386  401 YKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDVIINDSHNLKDVNLKWWRSKIGVVSQDPLLFSNSIKNNI 480 
124506379  396 YKDLSFTLKEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIVNDSHNLKDINLKWWRSKIGVVSQDPLLFSNSIKNNI 475 
221056887  401 YKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSHNLKDINLKWWRSKIGVVSQDPLLFSNSIKNNI 480 
156095386  481 KYSLYSLKDLEALSEESNEDGFSSQSDSNsrnscrakcagdLNDMIQTTDSTELIQVRKNYETIEDSEVVSVSKKVLIHD 560 
124506379  476 KYSLYSLKDLEAMENYYEENTNDTYENKN------------FSLISNSMTSNELLEMKKEYQTIKDSDVVDVSKKVLIHD 543 
221056887  481 KYSLYSLKDLEYLSDQLNEDGSASQDGLDkrnscrakcagdLNDMMKTTDSDGLIHARKNYNIIDDSEVVNVSKKVLIHD 560 
156095386  561 FVSALPDKYETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHRL 640 
124506379  544 FVSSLPDKYDTLVGSNASKLSGGQKQRISIARAIMRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHRL 623 
221056887  561 FVSALPDKYETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHRL 640 
156095386  641 STIRYANTIFVLSNRENGstvdvdvlg--edptkdsnEKNEKHDKQEKGGKNSSANQKIGNAGSYIIEQGTHDALMKNKN 718 
124506379  624 STIRYANTIFVLSNRERS-------------------DNNNNNNNDDNNNNNNNNNNKINNEGSYIIEQGTHDSLMKNKN 684 
221056887  641 STIRYANTIFVLSNREKGnrstvdvdiigedptkdnkENKQKNGKKG----DTNKNEKMSNAGSYIIEQGTHDALMKNKN 716 
156095386  719 GIYYTMINNQKVSSKSSSNNDNDKDSDMKSSIYKDSERGYDPDEANGNAK--NESASAKKSEKmsdaKASNTNAGGRLAF 796 
124506379  685 GIYHLMINNQKISSNKSSNNGNDNGSDNKSSAYKDSDTGNDADNMNSLSIheNENISNNRNCK----NTAENEKEEKVPF 760 
221056887  717 GIYYTMINNQKVSSKTSNNNDNDKDSDMKSSVYKDSERGYDPDEMNGNTKngNESASDKKSNKmsdeNASSKNAGGKLSF 796 
156095386  797 LRNLFKRKPKAPNNLRVVYREIFSYKKDIAIIALSIMVAGGLYPLFALLYAKYVGTLFDFANLEANSNKYSLYILVIAIA 876 
124506379  761 FKRMFRRKKKAPNNLRIIYKEIFSYKKDVTIIFFSILVAGGLYPVFALLYARYVSTLFDFANLEYNSNKYSIYILLIAIA 840 
221056887  797 LRNLFKRKPKAPNNLRMVYREIFSYKKDVVIIALSIIVAGGLYPMFALLYAKYVSTLFDFANLEANSNKYSLYILVIAIA 876 
156095386  877 MFISETLKNYYNNVIGEKVEKTMKLRLFENIMYQEISFFDQDSHAPGLLSAHINRDVHLLKTGLVNNIVIFTHFIVLFLV 956 
124506379  841 MFISETLKNYYNNKIGEKVEKTMKRRLFENILYQEMSFFDQDKNTPGVLSAHINRDVHLLKTGLVNNIVIFSHFIMLFLV 920 
221056887  877 MFISETLKNYYNNVIGEKVEKTMKHRLFENILYQEISFFDQDCHAPGLLSSHINRDVHLLKTGLVNNIVIFTHFIVLFIV 956 
156095386  957 STVMSFYFCPIVAAVLTGTYFIFMRVFAIRARIAANKDVEKKRvNQPGTAFVYNSDDEIFKDPSFLIQEAFYNMNTVIIY 1036
124506379  921 SMVMSFYFCPIVAAVLTFIYFINMRVFAVRARLTKSKEIEKKE-NMSSGVFAFSSDDEMFKDPSFLIQEAFYNMHTVINY 999 
221056887  957 SMIMSFYFCPIVAAVLTGTYFIFMRVFAIRARLSANKDVEKKGiNQPGTVFLYNNDDEIFKDPSFLIQEAFYNMNTVIIY 1036
156095386 1037 GLEDYFCTLIEKAIDYSNKGQKRKTLINSMLWGFSQSAQFFINSFAYWFGSFLIRRGTIQVDDFMKSLFTFLFTGSYAGK 1116
124506379 1000 GLEDYFCNLIEKAIDYKNKGQKRRIIVNAALWGFSQSAQLFINSFAYWFGSFLIKRGTILVDDFMKSLFTFIFTGSYAGK 1079
221056887 1037 GLEDYFCKLIEKAIDYSNKGQKRKTLVNSMLWGFSQSAQLFINSFAYWFGSFLIRRGTIEVDDFMKSLFTFLFTGSYAGK 1116
156095386 1117 LMSLKGDSENAKLSFERYYPLITRKSLIDVRDNGGIKIkNSNDIKGKIEIMDVNFRYLSRPNVPIYKDLTFSCESKKTTA 1196
124506379 1080 LMSLKGDSENAKLSFEKYYPLMIRKSNIDVRDDGGIRI-NKNLIKGKVDIKDVNFRYISRPNVPIYKNLSFTCDSKKTTA 1158
221056887 1117 LMSLKGDSENAKLSFEKYYPLIMRKSNIDVRDNGGIRIkNTNDIDGKIEIMDVNFTYMSRPNVPIYKDLTFSCDSKKTTA 1196
156095386 1197 IVGETGSGKSTVMSLLMRFYDLKNDHHIVfkneqTGESSKEQMQQGDEEQNVGMKNANEFSssKEGADGQSSTLFKNSGK 1276
124506379 1159 IVGETGSGKSTFMNLLLRFYDLKNDHIIL-----KNDMTNFQDYQNNNNNSLVLKNVNEFS--NQSGSAEDYTVFNNNGE 1231
221056887 1197 IVGETGSGKSTVMSLLMRFYDLKNDHHIVfknehTDDVNNEKKEQGDEEQNVGMKNVNEFSltKEGSHGDNSAVFKNSGK 1276
156095386 1277 ILLDGVDICDYNLKDLRNLFSIVSQEPMLFNMSIYENIKFGKENATREDVKRACKFAAIDEFIESLPNQYDTNVGPYGKS 1356
124506379 1232 ILLDDINICDYNLRDLRNLFSIVSQEPMLFNMSIYENIKFGREDATLEDVKRVSKFAAIDEFIESLPNKYDTNVGPYGKS 1311
221056887 1277 ILLDGVDICDYNLKDLRNLFSIVSQEPILFNMSIYENIKFGKEDATREDVKRACKFAAIDEFIESLPNKYDTNVGPYGKS 1356
156095386 1357 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASIKRSDKIVVFNNPDRTG 1436
124506379 1312 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASIKRSDKIVVFNNPDRNG 1391
221056887 1357 LSGGQKQRVAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADRTIITIAHRIASIKRSDKIVVFNNPDRTG 1436
156095386 1437 SFVQAQGTHEELLSVQDGVYKKYVKLAK 1464
124506379 1392 TFVQSHGTHDELLSAQDGIYKKYVKLAK 1419
221056887 1437 SFVQAEGTHEELLSVQDGVYKKYVKLAK 1464
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