Conserved Protein Domain Family
DUF5131

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pfam07505: DUF5131 
Protein of unknown function (DUF5131)
This is a family of bacterial and phage proteins of unknown function. There are three highly conserved cysteine residues in the disposition, Cx6Cxxc, amongst many highly conserved residues.
Statistics
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PSSM-Id: 429500
Aligned: 71 rows
Threshold Bit Score: 279.83
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Mpe_B0278   3 ETVIEWVRNpqgelgfTFNAWIGCEHVSPACDHCYAEVdTPARVLRAKGMETWGPHAE--------RYRTSDANWRQPLR 74 
Q2W5K3          5 TTEIAWATS-------TCNPFKGCSKVSPECANCYMTG-WAYRHQCMGNEGYegtvkgergkrvptgkigivEKQIESLK 76  Magnetospirill...
WP_015931569    4 NTKIEWCHH-------TFNPWVGCTRLSPACDHCYAEA-WAKRTGQPHLWT-----GE--------RRRTSASNWQQPLK 62  Methylobacteri...
WP_015930364    4 NSKIEWCHH-------TFNPWVGCTRISPACDHCYAEA-WAKRTGQPHLWT-----GE--------RRRTSASNWQQPLK 62  Methylobacteri...
Q21ZI9         27 ETTIEWTHH-------TFNPWWGCVKVSAACDHCYAET-WAKRLGDKV----WGAKSD--------RKFFTDAHWKEPLK 86  Rhodoferax fer...
ACR29184        4 NSKIEWCDH-------TFNPWIGCTKISPGCDNCYAEAmMDKRMHKVK----WGASAL--------RARTTPENWRLPVR 64 
ACR32808        4 TTDIGWTDS-------TFNAWEGCTAVSPGCANCYAER-RNRRFGSGTATN-WGPGAP--------RRRTAASTWAAPKR 66 
WP_012562697    4 RTEISWADA-------TFNPWIGCTKVGPGCDHCYAERdNGRRKWVDG----WGPGVP--------RRRT--KTWDAPLR 62  Afipia carboxi...
WP_009513349    4 YTKIEWCDH-------TFNPWIGCTKVSPGCAHCYAAAqDAFRHWTPAGF---GKGKP--------RKRTSEANWRQVLR 65  Opitutaceae ba...
WP_014197246    4 NSAIEWTDA-------TFNPWIGCTKVSPACDHCYAETlSKARLGVP-----WGAGQP--------RRRTSVQNWNLPLR 63  Azospirillum
jgi:Mpe_B0278  75 WNkkaa---------------------akgTRLRVFSASQSDWLDNKVPI--EWLVDLLDLIRCTPNLD-WLLLTKRIGN 130
Q2W5K3         77 TI----------------------------KTERLFVNSMSDTFHENVDD--LKVSRVFDSMKANGNGTnFLICTKRSAR 126 Magnetospirill...
WP_015931569   63 WDraaa---------------------aagERHRVFCASLADFFDHQVPS--RWRDNAWHLISQTPHLD-WMLLTKRPQN 118 Methylobacteri...
WP_015930364   63 WDraaa---------------------aagERHRVFCASLADFFDNQVPS--RWRDDAWHLINQTPHLD-WMLLTKRPQN 118 Methylobacteri...
Q21ZI9         87 WDrdae---------------------aagVRRRVFCASMADVFENR-PDlvQPRLRLLQLIDATPHLD-WLLLTKRIHL 143 Rhodoferax fer...
ACR29184       65 WNarhdef-----------------maahgRRQRVFCSSLADVFDNRVPS--SWRRDLFALIKATPNLD-WLLLTKRTGN 124
ACR32808       67 WNrghtkf-----------------falhgRRRRVFCSSLSDVFDNEVPA--QWRRDLADLILATPNLD-WQLLTKRIGN 126
WP_012562697   63 WDraaa---------------------lsgQRPRVFCASLADVFDNEVEQ--AWRTDLWALIRATPNLR-WMLLTKRIGN 118 Afipia carboxi...
WP_009513349   66 WDreaarfaeamtselkmafgpdgghldapRRPRVFCASLADWLDPEVPV--EWLTDLLDLIRRTQHLD-WQLLTKRPEL 142 Opitutaceae ba...
WP_014197246   64 WNrkae---------------------kegRRMRVFCASLADVFDAEVSD--EWRNDLFDLIDRAPNLD-WLLLTKRPAV 119 Azospirillum
jgi:Mpe_B0278 131 WRKRLEEAATyrlaviladtsdprrdalyqwikawldghppAHVWLGATVVNQEEVDRDVIKLLRTP-AAVRFLSMEPLL 209
Q2W5K3        127 MAEMSQTLDv------------------------------pDNIWMGTTCGCQSSL-HRLDDLRRTK-AKIRFVSVEPLL 174 Magnetospirill...
WP_015931569  119 IAKMLPGPAIgapaw----------------------gagwSNVWLGTTIEDRARL-RNLDALRAVP-AWVRFLSCEPLL 174 Methylobacteri...
WP_015930364  119 IAKMLPGPAIgapaw----------------------gegwPNVWLGTTIEDRARL-RNLEALRAVP-ARVRFLSCEPLL 174 Methylobacteri...
Q21ZI9        144 VRKQLPVGYEf-----------------------------pANVWLGATVENQDSADKRIKHLLDFTtPTVRFLSCEPLL 194 Rhodoferax fer...
ACR29184      125 AREMLIGSPLsp---------------------------ipDNVWLGATIVNQEEADRDIPKLLAVP-ARVRFLSIEPML 176
ACR32808      127 ASAMLTEMFPlg---------------------------ipGNVWIGATVVNQAEADRDIPKLLTIR-ASVRFLSIEPML 178
WP_012562697  119 AAKMLPPDwp------------------------------yPNAGLMATVVNQAEADRDIPKLMMTP-ATWRGLSIEPML 167 Afipia carboxi...
WP_009513349  143 WEKRIGQACGlagkrgmseagwsdt--wgmafdwlrggippANVWIGTTVENQDMADKRIPELLKIP-ARVRFLSVEPML 219 Opitutaceae ba...
WP_014197246  120 ARKVMPAtp-------------------------------rPNVWLGTTVESQAMAETRIPHLLATP-AAVRFLSMEPLL 167 Azospirillum
jgi:Mpe_B0278 210 GPVnitriDLDghseiyplrgttgc----------edddgepvadlpaiDWVIVGGESGHKARPMLPEWAFNVRDQCEAA 279
Q2W5K3        175 EPL-----DITpwla------------------------------dgtlKWVIVGGESGKGWRKMEKEWAEAILRQCQQF 219 Magnetospirill...
WP_015931569  175 EDLge--iDLTg------------------------------------iHLVIVGGESGPGARPMYPDWARSLRDQCQAA 216 Methylobacteri...
WP_015930364  175 EDLgq--vDLTg------------------------------------iHLVIVGGESGPGARPMHPDWARSLRDQCQTA 216 Methylobacteri...
Q21ZI9        195 GPI-----DLKkwlkfs--------------------------nkgtrvDWVIAGGESGPGSRPMEPHWPDGLREQCTSA 243 Rhodoferax fer...
ACR29184      177 GPI-----DLNqalppfhcdtcdady---------galsahasgtpigiDWVIAGGESGHRARPAHPDWFRSLRDQCAEA 242
ACR32808      179 GHI-----NLRrhlawpnhygle---------------lpqldrhrvgiDWVIAGGESGLLARSVHPGWIRSLRDQCAAA 238
WP_012562697  168 GPV-----DIShwltgh---------------------------egiglDWVICGGESGPHARPMHPSWPRSLRDQCAAA 215 Afipia carboxi...
WP_009513349  220 GPV-----DLYnhlhdpsggeewtsrpsd---lvqygiqdglplmrrgiHWVICGGESGPHARPMHPAWARSLRDQCAAA 291 Opitutaceae ba...
WP_014197246  168 GPV-----DLTrvvisegpaefyghpnitkarftvnalagvqsfgwrslDWVIVGGESGPKARPMHPDWARSLRDQCAAA 242 Azospirillum
jgi:Mpe_B0278 280 GVSFFFKQWGEWHT---SavrltdgravfrqftdfqhwvnkastwvnggicldrngvelkigrdfmrardedafpvtiMH 356
Q2W5K3        220 NVPFFLKQWSAFKPksdAey------------------------------------------------------------ 239 Magnetospirill...
WP_015931569  217 AIDYHFKQWGEWGPgaaFdatesaravyrgeiqtlhiag------------------sreiklamptrdddalgppltLE 278 Methylobacteri...
WP_015930364  217 GVAFHFKQHGHYAEvspEdhhrdyiraangkgpwpfdrv-------------------vdrdgtvlpgdsmcigtrvyMR 277 Methylobacteri...
Q21ZI9        244 GVAFHFKQWGHWAPielAvdamtrrtpih---------------------------------------vvmrdgaeikLV 284 Rhodoferax fer...
ACR29184      243 HVAFFFKQWGQWAPgsnWpedvpipsgera------------------------------------yldgqetddnesVW 286
ACR32808      239 GIPFFFKQWGEWRPapeiisaags--------------------------------------------mfhcfadgvwMQ 274
WP_012562697  216 GVAFHFKQWGEWAPhkispgsrgqiclwpngr-----------------------------egagigganenggggaeMD 266 Afipia carboxi...
WP_009513349  292 NVPFFFKQQGEWREplpgeeydtskgrassppafi-----------------------vapdgsvhcyhsdrtnggavMV 348 Opitutaceae ba...
WP_014197246  243 DVPFLFKQWGEWAPmdaArivkdipipprggihgdwvkryv--------------vfaddagavrvqaepfsaldntlMY 308 Azospirillum
jgi:Mpe_B0278 357 RVGKASAGRLLDGRLHDASP 376
Q2W5K3        240 -------ppTIDGQVWHQYP 252 Magnetospirillum magneticum AMB-1
WP_015931569  279 RYGKKAAGRLLDGRTWDQMP 298 Methylobacterium nodulans
WP_015930364  278 PMGKKAAGRLLDGRTWDQMP 297 Methylobacterium nodulans
Q21ZI9        285 GIGKGKAGRTLGGQHWDQFP 304 Rhodoferax ferrireducens T118
ACR29184      287 SVGKRAAGRLLDGRTHDEFP 306
ACR32808      275 RVGARDAGNLLDGIRHEAFP 294
WP_012562697  267 RVGKKRAGDLLDGREHKEFP 286 Afipia carboxidovorans
WP_009513349  349 RVGKKAAGRLLDGVEHNG-R 367 Opitutaceae bacterium TAV5
WP_014197246  309 RVGKKAAGRYLDGVLHDALP 328 Azospirillum
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