111221235   1 MVDRRDWMTRAADEAIE-RAQQRPGga---kVVCASGISPSGPIHLGNLREILVPHLVAEEIRSRGVPCEHILSWDDYDR 76 
292656002  23 ATHHGFWADEVADEIEA-RDPDEP-------VVVKGGVSPSGVAHLGNFNEIMRGYFVAEVLRERGHEVRQVFTSDDKDP 94 
222480795  31 KGFRAFWADVVADEIEA-RDPDEP-------IVIKGGVSPSGVAHLGNFNEIMRGYFVAAVLRERGHEVRQVFTSDDKDP 102
289581181  21 EMRYAFWADTVADQVEA-RVADQHPdedepeIVIKGGISPSGVPHLGNVNEILRGYFVAAVLRERGHEVRQVFTADDRDP 99 
76801778   10 GEKRPFWADAAADEVEA-RDPDEP-------VTIKGGVSPSGVPHLGHFNEIMRGYFVAEALRERGYEVRQVFTTDDKDR 81 
147920461   1 MVHRVFWADTLADEVIE-RYGKDGEvd--dtVVVKCAASPSGGKHIGNINDILRGYFIKESLKSMGVRTRHVHTSDDRDP 77 
284166734  16 DERHAFWADIVADRVEE-RNPDEP-------IVVKGGISPSGVPHLGNVNEIMRGYYVAEVLRERgheVRQVFTADDRDP 87 
257053042  12 DGTATFWADAVADAIEA-RDPEEP-------IVIKGGVSPSGVPHIGHLNEIVRGYVVAEVLRERDHEVRQVFTSDDRDR 83 
110667072  21 PQTHAFWAATAADEIEEtDPTDP--------IVIKGGVSPSGVAHLGNFNEVMRGYYIAEVLRERgheVRQVFTSDDRDP 92 
300710230  27 DRGFVFWADEMADEVEA-REPDEP-------IVIKGGISPSGVPHIGNVNEIMRGYFVAEVLRERGHEVRQVFTADDKDR 98 

111221235  77 LRKVPAGVPA--------------DFAEHVGRPLTAVPDPWGEFPSWAERFKAPFRDALRRLGIEVREISQTEMYRSGAY 142
292656002  95 LRKLPRKLADadgnivglgevdagALGRNLGKPYTSIPDPFGEAESYAAHFAALLKADADRLGVPVEMISNTELYDNGDF 174
222480795 103 LRKIPRKLANpdgeivglgevdagALGRNLGKPYTAIPDPFGERDSYAAHFAALLKADADRLEIPVEMVSNTELYADGAF 182
289581181 100 LRKLPRTLCDldgnlvdlgdvdagALGRNLGHPYTDIPDPFGCCDSYGDHFSTIIQDSADAVDVPIDMVSTTDLYTDGTF 179
76801778   82 LRKLPRKLADldwnvvglgevdagALGRNLGRPYTDIPDPFGCCDSYGAHFTELLRRSAEAIGVPIDLVSNTELYAGGDF 161
147920461  78 LRKIPERMPDregnwkilteqelkELNKYVGLPYVHVPDPFGCCKSWAEHFNNVWLDGVRSLGVEVEDYSNHALYNEGKF 157
284166734  88 LRKLPRTLCDlegnlvdlgevdagALGRNLGAPYTDIPDPFGCCDSYGDHFSTIIQDSADAVDVPIDLVSNTEMYENGDL 167
257053042  84 LRKIPRQLADlewnivglgevdagALGRNLGKPYTSIPDPFGCCDSYGAHFTTLLARSAELLDVPIDVVSNTELYADGEF 163
110667072  93 LRSLPQRLADdtgeivglgdvdagALGRNLGRPYTDIPDPFGESKSYAAHFTKLLAADADRLDIPVEIISNTEYYQEGKF 172
300710230  99 LRGLPRKLADlegnivdlgevdagALGRNLGKPYTAIPDPFGCCESYGAHFSTLIGRSAELLGVPIDVVSNTAMYADGEF 178

111221235 143 ADGIARAIAAAPTIDGILGRYRtlqpsptaapagsgpdgsgldgsgprasgaggsgpggragrggrragaapggaddvpp 222
292656002 175 DPVVEHVLDHADTAREVLGEY----------------------------------------------------------- 195
222480795 183 DDVTRRVLSDLDGVREVLSQY----------------------------------------------------------- 203
289581181 180 DDVTRHALANRDRAREVLAEY----------------------------------------------------------- 200
76801778  162 DAAVEDALANRDTAREVLSEF----------------------------------------------------------- 182
147920461 158 EAPTRTILSDIPLAREVISKYQ---------------------------------------------------------- 179
284166734 168 EEVTRFVLEHRDRAREVLSEY----------------------------------------------------------- 188
257053042 164 EKLTRHVLRNQDRAREVLKDY----------------------------------------------------------- 184
110667072 173 EESIKCILEDIDTAREVLSEY----------------------------------------------------------- 193
300710230 179 EGSTRTLLERRERAREVLGEY----------------------------------------------------------- 199

111221235 223 advdvaadegaADDegsaSASAYFPFRPYCEVCGRDTTVVA--SFDPAAG---QGDYs------------CSA----CGN 281
292656002 196 -----------QSK----VDEDYVPFNPVCAECGKITETVT--DIDLDAG---TVDYvctd------mtvGDNtidgCGH 249
222480795 204 -----------QDK----VDGEYVPFNPVCGECGKITETVTsvDLDAE-----TVEYvctd------mdvGDNtiegCGH 257
289581181 201 -----------QDK----VDEEYIPFNPICEECGKVTETVTdvTLEPEESdlpTVDYrctd------mdaGDRtidgCGH 259
76801778  183 -----------QDK----VDDEYVPFFPQCAECGLLTETVT--DIDLDDG---TVGYvcsd------veaGDDviegCGH 236
147920461 180 -----------KN-----TPEDYIPFNPICENCGRITAKAV--SVDLDNW---TVDYvceskslagefevPGC----GHK 234
284166734 189 -----------QDK----VDEDYVPFNPICEECGKITETVT--SVDLDAGeagTVDYrctdmd--agdqtIDG----CGH 245
257053042 185 -----------QAS----VDDEYVPFQVECASCGILTDGIT--DVEPADG---TVAYecrd------vtvGEEtiegCGH 238
110667072 194 -----------QSK----VDEDYVPFNPLCQNCGKITETVTdiDLDAQ-----TVTYhctdmt--ageraIEG----CGH 247
300710230 200 -----------QDG----VDDSYIPFLAECENCGHLTDRIT--GVDLESG---TVEYecvdve--ageqvIDG----CGH 253

111221235 282 HGRFDVRGpAnGKLVWKVDWPMRWAFENVAFEAGGVDHSSpgsSFTVGGSIVReVFGGEPPVYLPYSFVGVRgRAKLSGS 361
292656002 250 EGTATFRE---GKLPWRFEWPGQWQVLGVDFEPFGKDHAEg--SWPSGKDIAEnVLGIEPPVPMVYEWFTLN-GEALSSS 323
222480795 258 EGTATFRE---GKLPWRLEWPGQWDVLGVDFEPFGKDHAEg--SWPSGVDVARnVLGIEPPVPMVYEWFTLN-GEPLSSS 331
289581181 260 EGTATIRE---GKMPWRFEWPGQWGVLGVDFEPFGKDHAEg--SWPSGDDVARnVLDIEPPVPMVYEWFTLD-GEPFSSS 333
76801778  237 EGRATFRA---GKLPWRFEWPAQWRVLGVDFEPFGKDHAEg--SWPSGKAVSReVFDTEPPVPMVYEWFTLN-GDALSSS 310
147920461 235 GTTSLNNG----KLPWRFEWPSQWQIFDVKMEPFGKDHYEg--SWPSGQEISKvILKRQPPVYSVYEFFLVN-SAKMSTR 307
284166734 246 EGTATLRE---GKMPWRFEWPAQWKELGVDFEPFGKDHAEg--SWPSGQDVARnVFEIEPPVPMVYEWFTLE-GQPFSSS 319
257053042 239 EGEVSLRE---GKLPWRFEWPAQWDVLGVDFEPFGKDHAEg--SWPSGVDVARnVFEVEPPVPMVYEWFTLD-GEALSSS 312
110667072 248 EGVATFRE-G--KLPWRFEWPAQWQILDVDFEPFGKDHAEg--SWPSGTDIAEnVLDTVPPIPMVYEWFTVN-DESLSSS 321
300710230 254 EGTASLRD---GKLPWRFEWVAQWRALGVDFEPFGKDHAEg--SWPSGQDIARnVFDFEPPVPMVYEWFTLD-GEAFSSS 327

111221235 362 AGGAPTPADALHILEPAIVR-WIYARRRPNQAITVDFgaeVLRVYDEWDALNRRVGDGAAEPAen--tVVARSRGT---- 434
292656002 324 AGNIVTVAEMLDLLEPEVLRyFFALNPRKARDLDLTR---LDQLVDDFDRFERAYFGEVDDESlt--rFAERAYPF---- 394
222480795 332 AGNIVTVSELLDLLEPAVLRyFFALHPKKARDLDIER---LDQLVDRFDRFERAYFGEVDDEDlt--aFAERAYPF---- 402
289581181 334 EGNVILVSDVLELLEPEVLRyFFAKDPSRARDFSIER---LDQLVDEFDRFEATYFGEVAEATedeqaFADRVYPLvvee 410
76801778  311 AGNIITVDEVLELLEPAVLRyFFTKNPKKQRDFDVSN---LDRFVDEFDRFEAGYFGDESVEDde-raRADRAYPMvvde 386
147920461 308 HGNVYITQDMNKIMEPEAFLyFYSLNPMKQKNLEVKN---INFLVDGFDRFERLYYNEVEAADaeekeLADRVYPM---- 380
284166734 320 EGNVILVSDVLELLEPEVLRyFFAKDPSKARDFSIER---LDQLVDEFDRLEAIYFDEIEADEde-aaFAKRVYPLvvae 395
257053042 313 AGNVVTAAEVLELVEPAVLRyFFCKDPRKQRDFSIAH---LDQLVDEFDRLEAVYFGRQDADEed-reRAERVYPIavde 388
110667072 322 TGNIVTVTELLTLLEPAVIRyFFALDPRRARDLDLEN---LDQLVDDFDRFERAYFDGVNDESin--eFAEQAYPYvven 396
300710230 328 AGNVMLVSEVLDLVEPEVLRyFFAKDPSRARDFNVGR---IDLLVDEFDRVERIYFGEEEADEre-rqRAERIYPFcved 403

111221235 435 ----Vegg--------pvDAPrtv-----fpFRLLSSICDITAd--DPTQILRILRQ---ARGSDAAg-Gsgadaagqap 491
292656002 395 ----Vvdevre--drvrlPYT----------FAAVLGMTDDENlrvKMARNEGFFDEdtpDEVVEEAl------------ 446
222480795 403 ----VvrraddpptekpvRLP----------YTFAAVLGMV-----DDPAFRERLARd--EGHIPDDasdet------ve 455
289581181 411 vreeR--------------------------IRLPYTFAAVLGmtdDPDLREEIARR---EGHIPDDapewa------ve 455
76801778  387 ---------------lpeRQP----------VRIPYTFAAVLGmtdDRDLRLQMAQR---SGHIPDDatddq------ie 432
147920461 381 ----L-------------PIEkrrkiripytFAAMVSVSK------NEEHILRTLKKtghLPADATKeqE---------- 427
284166734 396 t------------reerlRLP----------YTFAAVLGMF-----DDPGLREAVARk--EGHIPDDapewa------ve 440
257053042 389 p------------reeriRIP----------YTFAAVLGMT-----DDPALREEIARr--EGHIPEDapewa------ve 433
110667072 397 idseR--------------------------VRLPYTFAAVLGmtdDRSLQIEMARNeghIDAETPEwaV---------- 440
300710230 404 a------------dtdriRLP----------YTFAAVLGMT-----DDPELREEIARr--EGHIPEDasges------ie 448

111221235 492 fslDDLQPRLDAARAWTREH----------VPAEQRTIVRTEP--DRAALAGLSAde--tkALAIL----VDgle---ed 550
292656002 447 -------GRVERARRWAEKMdnqynyrlqvDLPEFDFEPAVEA------------------ALDEL----ADfve---kn 494
222480795 456 aalARVEKARNWAERTANEY-------------------------DYRLQTELPDadfdddVAAAL----DDlaefvaag 506
289581181 456 qalARVERARNWARRTENEFdyel---krtEIPDHEFDAETED--ALAELADFIE---------------AGh------- 508
76801778  433 ralERVEKARAWAVRTDNEFn---------YRLAETLPAVDFDaeTAAALDELAA------FVETE----SP-------- 485
147920461 428 ---QDALTRVKLAGYWARNF----------GPEEYNISIKEDLeiPADITDAEKD------ALREM----ADyie---ar 481
284166734 441 dalARVEKARNWARRTGNEFdyel---krtEIPDHDFDAATED--ALAELADFIE---------------AGh------- 493
257053042 434 ealERVDRARAWARRTDNAF---------------------NYdlKREEMPDVDFdaetaaALDDLadfvATg------- 485
110667072 441 ---TDALNRIEKARIWAERM----------DNTYNYQLQETQPaiDIDPTSDTAK------ALDTLaevvAEg------- 494
300710230 449 nalARVELARNWARQTGNEY---------------------DYdlKRAELPAVAVdenterALSEL----ADfie---tg 500

111221235 551 wSLDGLTTLTYAVPKllrglpadapatTeLKQaQRAFFVLIYRLLVGRDTGPRLPTLLLAVGPERIRTLLAATA 624
292656002 495 hDGEAIQGEIYETARr-------------HDIeMGDFFAAGYRLFFDAEQGPRLGGFLGELERDFVVTRLRRED 555
222480795 507 hDGEAIQAEIYETA-------------RaHDVeVSDFFAAGYRLFFDDTQGPRLGEFLGELERDYVVARLRREA 567
289581181 509 -DPEEIQGEIYETAk------------R-NDIdTGEFFGAGYRLFFDEEQGPKLGPFLAKVDQEFVVARLRRER 568
76801778  486 -DDETLQGEIYETA-------------KrNDVdVGDLFSAGYRLFLDESEGPRLGPLLSAMDETFVVERLRREG 545
147920461 482 hTEEETQYEIFEMAk------------R-RDIkPARLFKTAYTLLLGKPRGPKLGPFVLALDTEFVTKRLRLEA 542
284166734 494 -EPDEIQGEIYETA-------------KrHDVdVGDFFGAGYRLFFDEDQGPKLGPFLAKVDREFVVARLRRER 553
257053042 486 aDGEAIQAEIYELA-------------EaYDLdVSDFFAAGYRLLFDLTEGPKLGPFLAKLDQEFVVGRLRRER 546
110667072 495 sDGEEIQEAIFDIAr------------D-YDIpVGEFFEVGYQLFFNQSAGPRLGKFLGELDAEFVVQRLRREG 555
300710230 501 hTPEEIQGEIYETA-------------KrNDVpVGDFFATGYRLFFDQEQGPKLGQFLGKLDREFVLARLRRER 561