Conserved Protein Domain Family
cwf21_SRRM3
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cd21376: cwf21_SRRM3 
cwf21 domain found in serine/arginine repetitive matrix protein 3 and similar proteins
Serine/arginine repetitive matrix protein 3 (SRRM3) may play a role in regulating breast cancer cell invasiveness. It may also be involved in RYBP-mediated breast cancer progression. SRRM3 contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.
Links
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Statistics
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PSSM-Id: 410602
Aligned: 12 rows
Threshold Bit Score: 112.913
Created: 10-Feb-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
A6NNA2        34 RAEEELRAa--EPGLVKRAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGV 101 human
XP_024997796  31 KAEEEVRLv--EPSLVKKAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGV 98  chicken
XP_018102352  31 KTEEEPRTt--EPNLVKKAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIHQKVGTFRQMLMEKEGV 98  African clawed frog
XP_007894873  50 KAEEEPKKm--EAGLAKKANREILDHERKRRVELKCMELHEMMEEQGYTPEEICQKVGAFRQMLMEKEGV 117 elephant shark
XP_006822349  36 KSEEELQKl--DQAMLKKPNQEILDHERKRKVELKCIELQELMEEQGYPEDKVKEKVAIFRQMLMDKEGV 103 Saccoglossus kowalevskii
RUS80882      36 KTEEEINKl--DQGLNRQPNREILDHERKRKVELKCMEMQELMEEQGYSEKEVANKVNMFRKMLMAKEGV 103 eastern emerald elysia
XP_017211705  34 PEEEEEQGvpsEPVLVKKTHREILDHERKRRVELKCMELQEMMEEQGYPEEDIRQKVETFRQMLMEKEGV 103 zebrafish
XP_002606480  36 KTEEEMKKl--DAAMSKKPNQEILDHERKRKVELKCMEMQELMEEQGYSEEEIDRKVATFRRMLMEKEGV 103 Florida lancelet
XP_023932406  36 KSEEELKKl--DQSMNKGPNQEILDHERKRKVELKCMEMQELMEEQGYPAEEVERKVAAFRKMLMDKEGV 103 Lingula anatina
ELT92430      36 KSEEEIKKl--DAEMARPPNEEILAHERKRKVELKCMEMQELMEDQGYTDEEIDRKVSTFRKMLMEKEGV 103 Capitella teleta
PIK44428      36 KSEEEIKKt--EAALSRPPNQEILAHERKRQVEIKCFEMQEHLEEQGHTEEEITRKVSAFRKMLMDKEGV 103 Japanese sea cucumber
XP_009025222  36 KSEEEIKKl--DWQLNKEPNQEILIHDRKRKIELKCLEMEELMEDQGYTQDEITKKVSAFRKMLMQKEES 103 Helobdella robusta
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