Conserved Protein Domain Family
bHLH_AtBIM_like

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cd11453: bHLH_AtBIM_like 
basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana BES1-interacting Myc-like proteins (BIMs) and similar proteins
The family includes Arabidopsis thaliana BIM1 and its homologs (BIM2 and BIM3), which are bHLH transcription factors that interact with BES1 to regulate transcription of Brassinosteroid (BR)-induced gene. BR regulates many growth and developmental processes such as cell elongation, vascular development, senescence stress responses, and photomorphogenesis. BIM1 heterodimerize with BES1 and bind to E-box sequences present in many BR-induced promoters to regulated BR-induced genes.
Statistics
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PSSM-Id: 381459
Aligned: 8 rows
Threshold Bit Score: 108.329
Created: 10-Jun-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative DNAputative dimer
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:The N-terminal basic region of bHLH mediates high-affinity DNA-binding to specific hexanucleotide sequences
  • Comment:Based on the structure evidence that Arabidopsis thaliana MYC2 (5GNJ) binds DNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1              ##  ## ##   #                     ##                                      
Q9LEZ3       275 NTPRSKHSATEQRRRSKINDRFQMLRQLIPNs----dQKRDKASFLLEVIEYIQFLQEKADKYVTSYQGWNHEPAKLLNW 350 thale cress
Q9CAA4        44 SAIRSKHSVTEQRRRSKINERFQILRELIPNs----eQKRDTASFLLEVIDYVQYLQEKVQKYEGSYPGWSQEPTKLTPW 119 thale cress
Q9FMB6        32 NSCRSKHSETEQRRRSKINERFQSLMDIIPQnq--ndQKRDKASFLLEVIEYIHFLQEKVHMYEDSHQMWYQSPTKLIPW 109 thale cress
XP_019575922 278 NTPRSKHSATEQRRRSKINDRFQMLRQLIPNs----dQKRDKASFLLEVIEYIQFLQEKTNKYEIPYQGWNPQPAKLLNW 353 Chinese rufous ...
EFN56128     134 VLFHAMHVQAEARRRSRINERLEALRLLVPHt-----ERANTANFLEEVVQYVQRLQSRVTDLERQLGLPASVAAGQKAI 208 Chlorella varia...
BAD44756     135 SAYASRHQAAEQRRRTRINERLELLRKLVPHa-----ERANTACFLEEVIKYIEALKARTLDLESQVEALTGKPVPKSLA 209 Chlamydomonas r...
XP_024396710 327 STPRSKHSATEQRRRSKINDRFQMLRDLVPHs----dQKRDKASFLLEVIEYIQVLQEKVRKYETTEQGRHQERLKSMVW 402 Physcomitrella ...
XP_004347270 183 IVRKVSHRAIERRRRTKINERLQALRDLIPGgagggsAMLHKAVVLDKVLMYMEALVKDNAILREQVVKLGGTPEPATMV 262 Capsaspora owcz...
Feature 1         
Q9LEZ3       351 Q 351 thale cress
Q9CAA4       120 R 120 thale cress
Q9FMB6       110 R 110 thale cress
XP_019575922 354 Q 354 Chinese rufous horseshoe bat
EFN56128     209 A 209 Chlorella variabilis
BAD44756     210 L 210 Chlamydomonas reinhardtii
XP_024396710 403 D 403 Physcomitrella patens
XP_004347270 263 A 263 Capsaspora owczarzaki ATCC 30864

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