Conserved Protein Domain Family
Adeno_52K

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pfam03052: Adeno_52K 
Adenoviral protein L1 52/55-kDa
The adenoviral protein L1 52/55-kDa is expressed in both the early and late stages of infection which suggests that it could play multiple roles in the viral life cycle. The L1 52/55 kDa protein interacts with the viral IVa2 protein and is required for DNA packaging. L1 53/55-kDa is required to mediate stable association between the viral DNA and empty capsid.
Statistics
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PSSM-Id: 308597
Aligned: 17 rows
Threshold Bit Score: 99.8561
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O10437  32 IARQLPATAAEGgrdpvacHPRVQLQQDMSESFVPAQNVLREDHSQgrgePEGSRHLRFQAGQHLHLNP--DTVLSGKDF 109 Murine adenovirus 1
P68972  25 LARLQGGAAPEV-------HPRVQMKQEAAEAYIPASNVFRDNEGEe---AEGLRHLKYESGRMLRKDHpsKRVLDERDF 94  Canine adenovirus 1 s...
Q2KSK6  10 LLPPVGGMAV-----------------DVMEVELPAT----------------------------------RRAF----- 33  Human adenovirus B3
Q96591  10 LLPPVGRMAV-----------------DVMKVEISSA----------------------------------DRAF----- 33  Human adenovirus 12
Q83899  32 EFEPAVGISSKPsde--fnMRRSQRDDNLPKSQIPVVDILHDKNPK----MAEERDLMYKSSACIKLDD--SKQLKTDMF 103 Ovine adenovirus 7
Q997I2  32 NKNFNVGIASKHdee--ttLRETQRNDKIPKSKIHKIDVFRDEEPK----MAEERDLIYNASNHISLNL--DKKLEPEMF 103 Bovine adenovirus 4
Q994E6  40 VARL-DAETPEQ-------HPRVQLKKDSGEAYVPRANSFREREGEe---GEGVRHVRFRSGEQMKLDR--RRVLEDRDF 106 Porcine adenovirus 5
Q9W9Q1  33 LARLSGAAAPER-------HPRVQLKREAMEAYVPRQNAFRERPGEe---GEEMRDLRFRAGREMQLDR--ERVLQPEDF 100 Porcine adenovirus 3
O71094  47 LARL--YAHPDT-------HPRVCVKRDAAEAYVPRENLFRDRSGEe---PEGSRDLKYKAGRQLRAGMprKRVLTEGDF 114 Bovine adenovirus 3
Q1L441  53 LARL-GAPSPER-------HPRVQLKKDSREAYVPQQNLFRDRSGEe---PEEMRASRFNAGRELRHGLdrRRLLQDEDF 121 Human mastadenovirus B
O10437 110 d--PSEESmaagpALSKGHAHVRAADLLTAYEQTVRQEQNFQQTFNNTIRCLLAREETTWGLMHLWDFAQALQRGPESPA 187 Murine adenovirus 1
P68972  95 e--KSPEN-----GISAAEAHLKSADLVTAYEHTVKAEVNFQTTFNNNVRTLIAREEVVIGLMHLWDFVEAFLENPVSKA 167 Canine adenovirus 1 s...
Q2KSK6  34 -------------MLVLVQTAAVIAAIHGMHLMNELYLTSFDEKFQWKIE--AWR--LYLALYYVV-----------CIG 85  Human adenovirus B3
Q96591  34 -------------MLMFVKACAVFASLHGLYLLNEVYLAASHQKADGKINT-TWQ--LPFVLFLFC-----------CIA 86  Human adenovirus 12
Q83899 104 ---RPDFA-----GTSPAQRHIEAAELKRNGSYTRSLEQWTHDSFISHVKQLLSRPFISLGITYLDDFLQTYLDHTESSS 175 Ovine adenovirus 7
Q997I2 104 ---KPDFP-----GTNAAQRHIEAAEVHRNGNHTRDLEQWCHDTFVSHAKQLLLRPNLSLGMTYLDDFLQTYLEHSNSSE 175 Bovine adenovirus 4
Q994E6 107 e--LDERT-----GVSPARAHMAAADLMTAYQQTVKEEVNFQKTFNNNVRTLVSREEVAVGLMHLWDFVEAYVGNPSSKA 179 Porcine adenovirus 5
Q9W9Q1 101 egrVEEAG-----GVSAARAHMSAASLAQAYEQTVREEVNFQKTFNNNVRTLVSRDEVTMGLMHLWDFVEAFLQHPRSRA 175 Porcine adenovirus 3
O71094 115 e--VDERT-----GISSAKAHMEAADLVRAYEQTVKQEANFQKSFNNHVRTLISREETTLGLMHLWDFAEAYAQNPGSKT 187 Bovine adenovirus 3
Q1L441 122 e--VDEVT-----GISPARAHVAAANLVSAYEQTVKEERNFQKSFNNHVRTLIAREEVTLGLMHLWDLMEAITQNPTSKP 194 Human mastadenovirus B
O10437 188 LRAQLFLVAQHCRDEGVFRESILNLGASE------SRWLLDLINLLQSIVvQERRLALEDKVAAIN 247 Murine adenovirus 1
P68972 168 LTAQLFLIVQHCRDEGVLRESLLNIAEPE------SRWLVDLLNLLQTIVvQERSLAVGEKVAAIN 227 Canine adenovirus 1 strain CLL
Q2KSK6  86 MTIFCLD---GGHADEPSREASPDLGAAG------AELEDESAQAGDVQG----PETLRSQVSRQC 138 Human adenovirus B3
Q96591  87 TTVWILE-SENGEGDGAPRAACPDFSTRG------AETGNQGVQPGAVHGiSQREKHVRGDSAQVD 145 Human adenovirus 12
Q83899 176 LNFQLFTLINHCS-ENTLKRILKHISKKNeknqyvNQWLIDLITCIYLII--RDEQNVTEQVNALL 238 Ovine adenovirus 7
Q997I2 176 LTFQLITLLSHTT-EPTLRRLLSSVSQKDskgnfkQQWLIDLVTCLYLII--RDEQNINERLSALL 238 Bovine adenovirus 4
Q994E6 180 LTAQLFLIVQHCRDDGVLKEALLNIAEPE------GRWLLDLINLLQTIVvQERALSLTEKVAAIN 239 Porcine adenovirus 5
Q9W9Q1 176 LTAQLLLIAQHCRDEGMVKEALLSLGAPE------SRWLVDLVNLLQTIVvQERSMSLSEKVAAIN 235 Porcine adenovirus 3
O71094 188 LTAQVFLIVQHLQDEGIFGEAFLSIAEPE------GRWMLDLLNILQSIVvQERQLSLSEKVAAVN 247 Bovine adenovirus 3
Q1L441 195 LTAQLFLVVQHSRDNEAFREALLNITEPD------GRWLYDLINILQSIIvQERSLGLAEKVAAIN 254 Human mastadenovirus B
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