1H54


Conserved Protein Domain Family
Glyco_hydro_65N

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pfam03636: Glyco_hydro_65N 
Glycosyl hydrolase family 65, N-terminal domain
This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. This domain is believed to be essential for catalytic activity although its precise function remains unknown.
Statistics
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PSSM-Id: 460999
Aligned: 297 rows
Threshold Bit Score: 86.0835
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1H54_A         14 THTFDpkdKRLQESMTSLGNGYMGMRGDFEEgysg-----------------dslqGIYLGGVWypdKTRv--------- 67  
Q0UJ45         42 TRTLD---QGHYQSRLSLANGYFGISVASAGpffetdiqdgaksvsgwplftqrqtFSTIAGFY---NNEpkpngtnypw 115  Parastagonosp...
CBX91091       53 TNKLD---QGHYQSRLTLANGYFGINVAAAGpffevdepvdgdvisgwplfsrrqgFSTIAGFW---NAQprtngsnypw 126 
XP_007703073   45 thALD---QGHYQSRLTLANGYFGINVASAGpffevdepvdgdvisgwplfsrrqaFSTIAGFW---NSQprtvgsnypw 118 
EDU51275       45 THALD---QGHYQSRLTLANGYFGINVASAGpffevdepvdgdiisgwplfsrrqaYSTIAGFW---NSQprtkgsnypw 118 
XP_007679943   36 TTSLV---QGQYQERMSLANGYLGINVAAVGpffevdtpvdgdningwpmfdrrqtFATIAGFY---DSQpllngtnfpw 109 
EGP89579       36 TTHLD---PHHYQSRMSLANGYLGINLAAIGpffdvddpvngdningwplfdrrqsFATIAGFW---DSQpetngtnfgw 109 
EME41206       37 TTHLD---QGHYQSRMSLANGYLGINLAALGpffdyddpvggdningwplfdrrqsFATIAGFW---DSQpttngtnfgw 110 
XP_016759360   41 TTTLD---QGHYQSRMSMGNGYLGINLAAVGpffdvdvqvngdniqgwplfdrrqsFATIAGFW---DSQpttngtnfgw 114 
EME77435       40 TTLLD---QAQYQSRFSLANGYLGINVAAVGpffdvdepvngdviqgwplydrrqsFATISGFW---DSQpttngtnfaw 113 
1H54_A         68 ----------GwwkngypkyfgkvvNAVNFIKLPIEINGepVDLAk--dKISDFTLDLDMHQGVLNRSFVVERGA---VR 132 
Q0UJ45        116 leqygwdsviA--------------GIPHWSGLQVDVHGerLNASvdpsSVEGFEASLHVKAGIANWRFVWKPAD---EE 178  Parastagonosp...
CBX91091      127 lyqygwesfvA--------------GIPHWSGLLVEANGemLNASvdskHVSDFVASLNVKTGIAGWRYNWTPGGeegAM 192 
XP_007703073  119 lyqygwesfiA--------------GIPHWSGLIVEANGefLNASvnpdHISDFVSSLDVKAGIASWRYNWKPGGqgdGT 184 
EDU51275      119 lyqygwesftA--------------GIPHSSGLIVEANGefLNASvnpdHISDFVSSLDVKAGIASWRYNWRPGGsgdVL 184 
XP_007679943  110 lnqyggesaiS--------------GIPHWSGLHLAVGGevLDASvpsdEISGFSSTVDFAAGVMTWHYTWSPSNgp--a 173 
EGP89579      110 lnqyggesviS--------------GVPHWGGLVVVAGEsvLDANvreeEVSGFSSTLDVRRGVMEWSFTWTPSGgv--p 173 
EME41206      111 lnqyggesviS--------------GVPHWAGLHVKVGDevLDARtpaeQVSDFSSSLDMRNAVMQWEFSWTPSGge--k 174 
XP_016759360  115 lnqyggesviS--------------GIPHWAGLHVKVGEdvLDASvpaeQISSFTSTLDMRNGVLHWNYTWTPTSgs--p 178 
EME77435      114 lnqyggesviS--------------GVPHWAGLPIQVGSdlLDASvpaeQISHFSSTLDVRNGAMYWNYTWTPSSas--p 177 
1H54_A        133 VALNFQRFLSVAQPELSVQKVTVKNLsdaEV-DVTLKPSIDADVMNeeanyderfwdvlatdqqadrgsIVAKTTPNpfg 211 
Q0UJ45        179 IEVEYQMFVHKLHVNQAAVRLRLTST---RDvDVTVYDVLDGEGAVrtravgkg--------ceedtptIWSAVRPG--- 244  Parastagonosp...
CBX91091      193 VDVEYEMFVHKLFVNKAAVRLRLTAT---KDvNVTVYDVLDGEAAVrsdfvdkr--------fetdapsIWSAVSPG--- 258 
XP_007703073  185 IDVNYQLFVHKLYINKAVVRLRLTST---RDdNVTVYDILDGDGAVrsdfvqkk--------fekdtptIWSAVSPG--- 250 
EDU51275      185 IDVDYQLFIHKLYVNKAATRLRLTAT---RDvNVTVYDVLDGDCAVrsefvdkk--------yeedtptIWSAVSPG--- 250 
XP_007679943  174 IDVDYTMLVHKLYVNQAAVQLKVTAS---RDvNASVIDVLDGDCAVrttfvdkm--------yepvlpmIWTAVSPN--- 239 
EGP89579      174 IGVQYEMLVHKLLVNVGLVRVQLTAE---RDvNVTVVDVLDGDCAVrtqfvgke--------yhsdrpmIHSGVSPD--- 239 
EME41206      175 IEVKYEMFVHKLYVSHAAVRVLLTPQg--KDaNVTVIDLLDGDCAVrstfveke--------yleslptVYSAVRPD--- 241 
XP_016759360  179 LDIEYTLLVHKLNVNQAAVQLRLTAA---EDlNATVIDLLQGDCAVrstpvdkg--------sfavwpvIWSAVSPD--- 244 
EME77435      178 IHVSYAMFVHKLHVNQAAVRLQLTAS---EDtNATIIDLLEGDCAVrtnfvekg--------sfpvwpvIWSAVSPD--- 243 
1H54_A        212 tpR-----------FTsgmEMRLvTDLKNVAITqpN--E----KEVTTAYTgkLAPQASAELEKRVIVVTS 265 
Q0UJ45        245 --NvanvtayvystLG--------MDEGAERRKvdAgtFnadnSTIAQAVRisLKASKSHEIKKFLGVASS 305  Parastagonospora nodor...
CBX91091      259 --NvtdvtayiystLR---GSEW-VDFSTRSQVddGafGagnvSTIAQSVRveLTAFRPTELNKFVGVAST 323 
XP_007703073  251 --NitnvtayvystLG---ASDW-VDLSARSEVadGvfGsgneSTIAQSVPveLTAFRPTEVTKFIGVAST 315 
EDU51275      251 --NitnvtayvystLS---SNDW-VDLAARSQVgdGifSsgngSTIAQSVPveLVAFRPTEITKFIGIAST 315 
XP_007679943  240 --GvsnvtayvvsaMV---GDEY-CDSGSRMNYtmSsvIggnsSSIAQAMNvsLIAGQTSTITKYIGAASS 304 
EGP89579      240 --GlsnvtayiastLV---GDDS-CNATSRRLFdtEsvTgsnsSTIAQAMDvaLTGGKTSTITKHIGGASS 304 
EME41206      242 --GisnvtayvystLV---GDES-CDLGTRQRYdeAslTgn-aSSIAQSIVvaLTAGKTSTITKYIGGASG 305 
XP_016759360  245 --GirnvtawvhsaLV---GDQT-CDTASRRIItdSdiVgsnsSSIAQSLDvsLVGGCTSVITKYIGTASS 309 
EME77435      244 --GlrnvtaylfsaLI---GDDH-AVSGSRKIIqeGdvVggnsSSIAQSIQvaLARGTTATVTKYVGAASG 308 
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