Conserved Protein Domain Family
strep_PBP2A

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NF038276: strep_PBP2A 
streptococcal penicillin-binding protein PBP2A
Statistics
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PSSM-Id: 439576
Aligned: 61 rows
Threshold Bit Score: 1342.34
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_017768686  64 KKGRRASryqkyghqkhddrvrlrdrllrryprlaviKRVIPD--RDGWFRRFWRRYHIGKLLLLVIAIVSLFVGSYLFY 141 Streptococcus a...
WP_006595431  40 TYSRSEK------------------------------SRRKSH--SQHPIRRFWRKYHLTKIFLLIGLTFSLIVGGYLFY 87  Streptococcus a...
WP_014714039  41 TYSRSGK------------------------------HRSKPL--SQHPFRRFWRRFHLTKILLIIGLGFSLLTGGYLFY 88  Streptococcus p...
WP_009731837  41 TYSRSGK------------------------------HRSKPL--SQHPFRRFWRRFHLTKILLIIGLGFSLLTGGYLFY 88  Streptococcus s...
WP_018371433  35 SLSRSGK------------------------------GGHKKL--SQNPFRRFWRKYHLTKIILILGLGFSLLVGGYLFY 82  Streptococcus m...
WP_012130984  35 RLSRSGR------------------------------SAKRTSskGQGPFRRFWRRYHLTKIILILGLGFGLVTGGYLFY 84  Streptococcus
WP_009754743  34 QMSRAGR------------------------------SSQKFT--GKGPFRRFWRKYHLTKIFLILGLGFGLIVGGYLFY 81  Streptococcus s...
WP_006269711  36 HLSRSGK------------------------------SRKKPI--SQHPFRQFWRRYHLTKIVLILGLGFGLVTGGYLFY 83  Streptococcus c...
WP_009567825  36 HLSRSGK------------------------------SRKKPI--SQHPFRRFWRRYHLTKIVLILGLGFGLVTGGYLFY 83  Streptococcus i...
WP_002926340  38 GLSRSGK------------------------------TKKKPL--SQHPIRRFWRRFHLTKIFLILGLTFGLVVGGYLFY 85  Streptococcus s...
WP_017768686 142 LAKTSNVEDLQSALKATTLIYDKDEEQVGSLSGQKGTYVELDAISDNLEKAVISTEDRTFYKNNGINFSRFAFALVTMGK 221 Streptococcus a...
WP_006595431  88 IAKTTNVADLQNALKATTIIYDKDGNQAGSLTGQKGTYVELDAISENLQNAVVATEDRSFYKNSGINYGRFFLAILTAGR 167 Streptococcus a...
WP_014714039  89 LAKTTNVKDLQNALKATTIIYDKNGDQAGSLTGQKGTYVELDAISENLQHAVVATEDRSFYKNSGINYGRFFLAILTLGR 168 Streptococcus p...
WP_009731837  89 LAKTTNVKDLQNALKATTIIYDKNGDQAGSLTGQKGTYVELDAISENLQNAVVATEDRSFYKNSGINYGRFFLAILTLGR 168 Streptococcus s...
WP_018371433  83 IAKSTNVKDLQNALKATTVIYDRENKEAGTLTGQKGTYVELDAISKDLQNAVIATEDRSFYKNSGINYGRFLLAILTAGR 162 Streptococcus m...
WP_012130984  85 VAKTTNVNDLQNALKATTMIYDKDGQEAGSLTGQKGTYVELDQISKDLQNAVIATEDRSFYKNSGINYGRFFLAILTAGR 164 Streptococcus
WP_009754743  82 VAKSTNVNDLQNALKATTLIYDKEGKEAGSLTGQKGTYVELDQISKDLQNAVIATEDRSFYKNSGINYGRFFLAIVTAGR 161 Streptococcus s...
WP_006269711  84 VAKSTNVNDLQNALKATTSIYDKDGKKAGSLSGQKGTYVELSKISPNLQHAVIATEDRSFYKNSGINYGRFILAILTAGR 163 Streptococcus c...
WP_009567825  84 VAKSTNVNDLQNALKATTAIYDKDGKKAGSLSGQKGTYVELSKISPNLQHAVIATEDRSFYKNSGINYGRFILAVLTAGR 163 Streptococcus i...
WP_002926340  86 VAKTTNVKDLQNALKATTLIFDKDGNEAGSLSGQKGTYVELTEISQDLQNAVIATEDRTFYENGGINYSRFILAILTAGR 165 Streptococcus s...
WP_017768686 222 FGGGSTITQQLAKNAYLSQEQTITRKAKEFFLALELTKEYSKDEILTMYLNNAYFGNSVWGVEDASQKYFGRSAAELTLE 301 Streptococcus a...
WP_006595431 168 SGGGSTITQQLAKNAYLSQDQTVERKAKEFFLALEINKKYSKKEILTMYLNNAYFGNGVWGIEDASKKYFGVSASELTLD 247 Streptococcus a...
WP_014714039 169 SGGGSTITQQLAKNAYLSQDQTVERKAKEFFLALEINKKYSKKEILTMYLNNAYFGNGVWGIEDASKKYFGVSASQLSLD 248 Streptococcus p...
WP_009731837 169 SGGGSTITQQLAKNAFLSQDQTVERKAKEFFLALEINKKYSKKEILTMYLNNAYFGNGVWGIEDASKKYFGVSASQLSLD 248 Streptococcus s...
WP_018371433 163 SGGGSTITQQLAKNAYLSQDQTIERKAKEFFLALEITKKYSKKQILTMYLNNSYFGNGVWGVEDASKKYFGVSASQLSLD 242 Streptococcus m...
WP_012130984 165 SGGGSTITQQLAKNAYLSQDQTIERKAKEFFLALELTKKYSKDQILTMYLNNSYFGNGVWGVEDASKKYFGVSASQLSLD 244 Streptococcus
WP_009754743 162 SGGGSTITQQLAKNAYLSQDQTIERKAKEFFLALELTKKYSKDQILTMYLNNSYFGNGVWGVEDASKKYFGVSASQLSLD 241 Streptococcus s...
WP_006269711 164 SGGGSTITQQLAKNAYLSQDQTIERKAKEFFLALELTKKYSKKQILTMYLNNSYFGNGVWGVEDASKKYFGVSASQLTLD 243 Streptococcus c...
WP_009567825 164 SGGGSTITQQLAKNAYLSQDQTIERKAKEFFLALELTKKYSKKQILTMYLNNSYFGNGVWGVEDASKKYFGVSASQLTLD 243 Streptococcus i...
WP_002926340 166 SGGGSTITQQLAKNAYLSQDQTIERKAKEFFLALEINKKYSKQEILTMYLNNSYFGNGVWGVEDASKKYFGVSASQLSLD 245 Streptococcus s...
WP_017768686 302 QSAILAGMLKGPEIYNPIYSIENATNRRNTILSVMVDAKAISQEEADQAASVDIASELIDTYSGTSDTYQYPSYFDAVME 381 Streptococcus a...
WP_006595431 248 QSAVLAGMLKGPEIYNPLYSVENATNRRNTVLQNMVAAGYIDQATADQSAAVDIHGQLIDAYEGKSEDYRYPSYFDAVIN 327 Streptococcus a...
WP_014714039 249 QSAVLAGMLKGPEIYNPLYSVENATNRRNTVLQNMVAAGYIDQKTADQSAAVDIHGQLVDAYEGKSEDYRYPSYFDAVIN 328 Streptococcus p...
WP_009731837 249 QSAVLAGMLKGPEIYNPLYSVENATNRRNTVLQNMVAAGYIDQATADQSAAVDIHGQLVDAYEGKSEDYRYPSYFDAVIN 328 Streptococcus s...
WP_018371433 243 QSATLAGMLKGPELYNPIASVKNATNRRNTVLQNMMAAGYIDKTTADQAAAIGLGGQLVDAYTGKSEDYRYPSYFDAVIN 322 Streptococcus m...
WP_012130984 245 QAATLAGMLKGPEIYNPLYSVENATNRRDTVLNNMVAAGYIDKATADQAAANGLGSQLVDAYAGKSEDYRYPSYFDAVIN 324 Streptococcus
WP_009754743 242 QSATLAGMLKGPEIYNPLYSIENATNRRNTVLQNMVAAGYINQDTANQAAANGIGSQLVDAYTGKSEDYRYPSYFDAVIN 321 Streptococcus s...
WP_006269711 244 QSATLAGMLKGPELYNPLASIKNATNRRNTVLQNMVAAGYINQNTANQAAANGLGSQLVDAYTGKSADYRYPSYFDAVIN 323 Streptococcus c...
WP_009567825 244 QAATLAGMLKGPELYNPLASIKNATNRRNTVLQNMVAAGYINQATANQSTAIGLGSQLRDAYTGKSADYRYPSYFDAVIN 323 Streptococcus i...
WP_002926340 246 QSAVLAGMLKGPEIYNPLYSVENATNRRNTVLQNMVAAGFIDQGTADQAAAVGIGGQLVDAYAGKSEDYRYPSYFDAVIN 325 Streptococcus s...
WP_017768686 382 EATRDYGLSEDDIVNKGYKIYTELDQNYQVGMQYVFDNTAYFPVAA-DGEIAQGASVAMDPKTGAVRGLVGRVSST-SQS 459 Streptococcus a...
WP_006595431 328 EAVNEYGLTEEDIIKNGYRIYTEMDQNYQASMQVIYDNVDLFPVAE-DGTRAESGSVALDPKTGGVRAIVGRVASDqDVG 406 Streptococcus a...
WP_014714039 329 EAVNEYGLTEEDIVKNGYRIYTELDQNYQASMQVIYDNTALFPVAE-DGTRAESGSVALDPKTGGVRALVGRVGSDeNPG 407 Streptococcus p...
WP_009731837 329 EAVNRYGLTEEDIVKNGYRIYTELDQNYQASMQVIYDNTALFPVAE-DGTRAESGSVALDPKTGGVRALVGRVGSDeNPG 407 Streptococcus s...
WP_018371433 323 EAAANYGLSEAEIVNNGYKIYTELDQNYQASMQVIYDNESLFPVAEsDGTRAQGGSVALDPKTGGVRALVGRVNSDqNAA 402 Streptococcus m...
WP_012130984 325 EAIHDYGLKEEDIIKNGYRIYTELDQNYQASMQVIYSNESLFPVSEvDGTRAESGSVALDPKTGGVRALVGRVNSQ-TAG 403 Streptococcus
WP_009754743 322 EAIHDYGLTEEDIIKNGYRIYTELDQNYQASLQVIYSNESLFPVAEaDGTRAESGSVALDPKTGGVRALVGRVNSQ-SAG 400 Streptococcus s...
WP_006269711 324 EAVRDYGLTEADIVNNGYRIYTELNQNYQASMQVIYDRKDLFPQAA-DGTRAQSGSVALDPKTGGVRALVGQINST-SAN 401 Streptococcus c...
WP_009567825 324 EAVRDYGLTESDIVNNGYRIYTELDQNYQASMQVIYDRKDLFPQAA-DGTRAQSGSVALDPKTGGVRALVGQINST-SAN 401 Streptococcus i...
WP_002926340 326 EAVNDYGLTEEEIVNNGYRIYTELDQNYQASMQVIYSNVSLFPVAE-DGTMAESGSVALDPKTGGVRALVGRVNSAeGST 404 Streptococcus s...
WP_017768686 460 FRSFNYATQAKRSPGSTIKPLVVYAPAIAEGYSINRLLPNTPIDYNGYQPENYAGYV-SEDVPMYQALANSYNVPAVYLL 538 Streptococcus a...
WP_006595431 407 FRSYNYATQSARSPGSTIKPLVVYSPAVADGWSTNKELDNTTKVYGSYTVNNYGGIQgSPTVPMYQALAESLNLPAVATA 486 Streptococcus a...
WP_014714039 408 FRTYNYATQAARSPGSTIKPLVVYSPAVAAGWSTNKELDNSTTQYGSYEVNNYAGIQsSPTVPMYQALAESLNLPAVATA 487 Streptococcus p...
WP_009731837 408 FRTYNYATQAARSPGSTIKPLVVYSPAVAEGWSTNKELDNSTTQYGSYEVNNYAGIQsSPTVPMYQALAESLNLPAVATA 487 Streptococcus s...
WP_018371433 403 FRSFNYATQSGRSPGSTIKPLVAYSPAIAAGWAVDKLLDNNTTSYGNYKVDNYAGIKsSPTVPMYQALAESLNIPAVATV 482 Streptococcus m...
WP_012130984 404 FRSFNYATQSARSPGSTIKPLVVYSPAIAAGWSTDKELDNTTTTYGSYTVNNYGGIQtSPTVPMYQALADSLNIPAVATV 483 Streptococcus
WP_009754743 401 FRSFNYATQSSRSPGSTIKPLIAYSPAVAAGWPIDKELDNHTTIYGTYVVNNYGGIQtSPTVPMYQALADSLNLPAVATV 480 Streptococcus s...
WP_006269711 402 FRSFNYATQSSRSPGSTIKPLVVYSPAVDAGWSINKELDNSTTTYGNYTVNNYAGIQsSPTVPMYQALAQSLNIPAVAAA 481 Streptococcus c...
WP_009567825 402 FRSFNYATQSARSPGSTIKPLAVYSPAVAAGWSINKELDNSTTTYGNYTVNNYGGIKsSPTVPMYQALAQSLNIPAVAAA 481 Streptococcus i...
WP_002926340 405 FRSFNYATQSSRSPGSTIKPLVAYSPAVAAGWPTDKELDNTRTTFGDYTINNYGNIQsSPKVPMYQALAESLNIPAVSTV 484 Streptococcus s...
WP_017768686 539 DKMGVSTAFNYGKKFGINMSTANEELGVALGGSVTTSPLDIAQAYATFANNGVMPRAHLITRIETASGKIIKQFKESHKR 618 Streptococcus a...
WP_006595431 487 NELGLNTVFDYGTKFGLNMDKVDRSLGVALGSGVTTNPLQMAQAYGTFANDGVMNDAHLITKIENASGQVVKSHSQKSKR 566 Streptococcus a...
WP_014714039 488 NDLGLDTVFEYGKKFGLNMDKVDKSLAVALGAGVTTNPMQMAQAYGTFANGGVMNDAHLITKIENASGQVVKSHSQKSTR 567 Streptococcus p...
WP_009731837 488 NDLGLNTVFEYGKKFGLNMDKVEKSLAVALGAGVTTNPMQMAQAYGTFANGGVMNDAHLITKIENASGQVVKSHSQKSTR 567 Streptococcus s...
WP_018371433 483 NELGLKKAFEYGKKFGLNMDKVDQTLGVALGSGVTTNPLQMAQAYSTFANGGVMNDAHLITKIENASGQVIKSHKQTSTR 562 Streptococcus m...
WP_012130984 484 KELGIEKAFEYGQKFGLNMKKVEQNLSVALGAGVNTNPLQMAQAYSAFANDGVMHDAHLITKIENASGQIVKTHKSSSTR 563 Streptococcus
WP_009754743 481 KELGLKKAFEYGQKFGLNMKKVEQNLSVALGGGVTTNPLQMAQAYSTFANGGVMNDAHLITKIENASGQVVKTHKSSSTR 560 Streptococcus s...
WP_006269711 482 NELGLKKVFEYGKKFGLNMDKVSQTLGVALGSGVTTNPLQMAQAYSTFANNGVMNDAHLITKIENASGQVVKTHKSTSTR 561 Streptococcus c...
WP_009567825 482 NELGLKKVFEYGKKFGLNMDKVEQTLGVALGSGVTTNPLQMAQAYSTFANNGVMNDAHLITKIENASGQVVKTHKSTSTR 561 Streptococcus i...
WP_002926340 485 DELGINKAFEYGKKFGLNMDKVDKTLGVALGSGVTTNPMQMAQAYSVFANGGVMNDAHLITKIENASGQVVKTHRQTSTR 564 Streptococcus s...
WP_017768686 619 VISQSANAKMTSMMLGTFSNGSAVNANAYGYTMAGKTGTTETEFDPNLASDQWVVGYTPDVVLSQWIGFDKTDESHYLSD 698 Streptococcus a...
WP_006595431 567 VLSSSANKKMTNMMLGTFTNGTGVNAAPYGYTMAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWLGFPKTDETHYLTG 646 Streptococcus a...
WP_014714039 568 VLSGSTTDKMTNMMLGTFSNGTGVNAAPYGYTMAGKTGTTETSFNKDLSGDQWVIGYTPDVVISQWLGFPTTDENHYLTD 647 Streptococcus p...
WP_009731837 568 VLSGSATDKMTNMMLGTFSNGTGVNAAPYGYTMAGKTGTTETSFNKDLSGDQWVIGYTPDVVISQWLGFPTTDEGHYLTD 647 Streptococcus s...
WP_018371433 563 VLSQANTDKMTEMMLGTFTNGTGVYAAPYGYNMAGKTGTTETDFNPDVSGDQWVIGYTPDVVISQWLGFEKTDENHYLTG 642 Streptococcus m...
WP_012130984 564 VLNQSTAKKMTSMMLGTFSNGTGIYAAPYNYTMAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWLGFPKTDENHYLTG 643 Streptococcus
WP_009754743 561 VLSQSDNEKMTSMMMGTFSNGTGIYAAPYNYTMAGKTGTTETSFNPDLSGDQWVIGYTPDIVISQWLGFPTTDESHYLTG 640 Streptococcus s...
WP_006269711 562 VLNRSTTEKMTSMMLGTFTNGTGVYAAPYGYTMAGKTGTTETNFNPDLSGDQWVIGYTPDVVISQWLGFPKTDENHYLTG 641 Streptococcus c...
WP_009567825 562 VLNRSTTEKMTSMMLGTFTNGTGVYAAPYGYTMAGKTGTTETNFNPDLSGDQWVIGYTPDVVISQWLGFPKTDENHYLTG 641 Streptococcus i...
WP_002926340 565 VLNGSTTDKMNSMMLGTFSNGTGIYAAPYGYTMAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWLGFPKTDETHYLTG 644 Streptococcus s...
WP_017768686 699 AsSGTASTLFSAVASNVLPYTQGSTF-DVENAYISDGLTPTYTANPEeaGDSSAPSVSNIFDDLKKGAESAKNNFDKAVQ 777 Streptococcus a...
WP_006595431 647 TsAETASVIFRNVANSVLPYTEGTSFdNEKNSYQENGIAPVGQETET----ESPEEDKGFFDTVKERAAGIVDDAKKAID 722 Streptococcus a...
WP_014714039 648 SsAGTASEIFRNVANSVLPYTDGTQFdSVKNSYAENGIAPVGEET----TETDSKEDKGFFEDVKEKASNMVDDAKKAID 723 Streptococcus p...
WP_009731837 648 SsAGTASEIFRNVANSVLPYTDGTQFdSVKNSYAENGIAPVGEEN----TETDTKEDKGFFEEVKEKATNMVDDAKKAID 723 Streptococcus s...
WP_018371433 643 TsANEASAIFRATANSILPYTEGTKF-EDKSTYAQNGIAPVNTYDTGedNTQNQSQSKDFLQDIQDRAKNLVDDAKKAID 721 Streptococcus m...
WP_012130984 644 TsANEASVIFRNVANSVLPYTEGTKF-SEKNTYAQNGIAPVDTYGT---GNTENQGGNDFLQNVQDKAKEIVDQAKNAIE 719 Streptococcus
WP_009754743 641 TsANEASAIFRNVANSILPYTEGTQF-TEKNAYAQNGIAPVDTYGN---GDEKNQSNSNFLQNVQDKAKELVDQAKNAIE 716 Streptococcus s...
WP_006269711 642 TsANEASAIFRSVANSILPYTKGTKF-GDENAYAKNGIAPVDTSGTNn-TTNQSDNRSDVLKDVQDKAKNLVDQAKKAID 719 Streptococcus c...
WP_009567825 642 TsANEASAIFRSLANSILPYTNGTKF-GDKNAYAKNGIAPVDTAGTNn-TRNQGGSNSDILKDVQDKAKNLVDQAKKAID 719 Streptococcus i...
WP_002926340 645 TsANEASAVFRNVANSILPYTEGTSFeGQKNAYAANGIAPVDTYGTE--ETGTTTENKDFLQDVQDRAQNLVDEAKKAID 722 Streptococcus s...
WP_017768686 778 DANLGDKARRAWDLIQGWLN 797 Streptococcus agalactiae
WP_006595431 723 EADIPGKAQNAWDTFKGWFG 742 Streptococcus australis
WP_014714039 724 EADIPGKAKNAWDTFKGWLG 743 Streptococcus parasanguinis
WP_009731837 724 EADIPGKAKNAWDTFKGWLG 743 Streptococcus sp. F0442
WP_018371433 722 RYQIPEKAKSLWDGITSLFQ 741 Streptococcus massiliensis
WP_012130984 720 EADIPGKAKNAWDTVKSWFG 739 Streptococcus
WP_009754743 717 EADIPGRAKNAWDTVKSWFG 736 Streptococcus sp. oral taxon 056
WP_006269711 720 DAKIPEKAKNLWDTVKSWFQ 739 Streptococcus constellatus
WP_009567825 720 DAKISEKAGNLWDAVKSWFR 739 Streptococcus intermedius
WP_002926340 723 DTGIPEKAKNLWDTVTSWFQ 742 Streptococcus sanguinis
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