Conserved Protein Domain Family
Hia
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COG5295: Hia 
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures]
Links
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Statistics
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PSSM-Id: 444098
Aligned: 126 rows
Threshold Bit Score: 73.651
Created: 9-Feb-2022
Updated: 24-Feb-2022
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_083231440  263 NATSLGSRANASGINSTAMGNLASSAGTQSIAAGFTATASGLSSAAFGSFARASGLQGVAVGDASIASANFTVAIGANSN 342 
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WP_046328838      --------------------------------------------------------------------------------     
WP_046328839      --------------------------------------------------------------------------------     
WP_046328840      --------------------------------------------------------------------------------     
WP_046328842      --------------------------------------------------------------------------------     
WP_046328923    1 MNKNTRQILIIILFVITGSITLSENRINEFEIGENSYVKGSDGISLTKNSIAIGTNSNSLDNYFEYYNSNLIDKSKIENE 80  
WP_046328950    1 -----------------MNILGKYKIYLIILSMICSYTFAEHYDVVGAQGYGVHIDDKNVKVNLKLMDDKEYKKINDMAE 63  
WP_046328951    1 -----------------------------------------------------------MKKTILFIMLLGCMISEAEIK 21  
WP_046329073      --------------------------------------------------------------------------------     

WP_083231440  343 AATSGSVAIGQNSTTVTTGSTPSGAASLGTAVAIGNGARATQEDAVALGDLANASGFHATAIGGESVASGVGSQAFGWQA 422 
WP_012858630      --------------------------------------------------------------------------------     
WP_046328838    1 ----------------------------------------------------MKKIILFSCFLSVLSLAIEPYAVDNNGN 28  
WP_046328839      --------------------------------------------------------------------------------     
WP_046328840    1 --------------------------------------MKNKIVLSILLILGIFSFADEEGKWKEAYNGENSYYFGENTW 42  
WP_046328842      --------------------------------------------------------------------------------     
WP_046328923   81 IQKTKADIDNRVKDIKEQYINKLKRINSIESQMKIINDFFIDKQKVETQLKQVTDDREKFREFANIIILKNIEINKKFGT 160 
WP_046328950   64 NEVLNRHTTELVKYFNNIIDNSKFNDRIYNNSIINITNELEKKIFKDNDPETFSMYTGRLYGYYFKGEQEYNKNNSAENP 143 
WP_046328951   22 TIENKEVNDPTSIIISPYNISKITNSNWSNIFGASDTITNSNFSNILGTSNKINNSKQTSVIGELNEVVESENTKLLGNN 101 
WP_046329073    1 ------------------------------------------MKKSILICAALTMLASVGYSDKNDGNVTIDGASNIILK 38  

WP_083231440  423 NASGRTAVAVGHQVTAAGFEATSVGKSTNAGGANATAVGSRASAAGISSVAIGNNAVTADGTTPSGAPSTGTAVAIGNGA 502 
WP_012858630      --------------------------------------------------------------------------------     
WP_046328838   29 IIINGEKDFKNLTENSSGNFLFGFGHKVKTGFHNFLIGYNNNFEIGKNSLMLGNENNILNKGKYNNNDGIMLIGDNNKVT 108 
WP_046328839      --------------------------------------------------------------------------------     
WP_046328840   43 VDGNNAYSIGNDNYIYGNNNQVHGDKNKVGGENSRIDKNLVFGNNNEIYPDPVNKATREYKVFWAVELPSGQNVRGVRSI 122 
WP_046328842      --------------------------------------------------------------------------------     
WP_046328923  161 PIGDYRATLRKIADYLIDKKGLVGETIENITFKDEADDNRNSNLSKAKIKGFINDQVVWDYLKLDDEKNLKKYLSDCISY 240 
WP_046328950  144 MPKNKESEDEIIRRYIREGLSKDIIEIYGKNFKKLKQSNEELKNEINKEIKDVLIEKDGKKYCPPKITLFSNNAVVKKGT 223 
WP_046328951  102 NKINNSKYSYIFGGNIQAENSNHANIQGNKNIIKDSDQTTAIGEKNTITNSNQTTAIGELNEVVKSEKTKLLGDNNKINN 181 
WP_046329073   39 PSIDNKINGYDNVIGGRNNEVNDEFLDIAIANKDKSEAEIKKEISKELGKKYKKVLDIVKANENKKYNKNDKTPDGKKPE 118 

WP_083231440  503 RATAEDAVALGDLANASGFHATAIGGESVASGVGSQAFGWQANASGRTAVAVGHQANASGLEATSIGKSALAGGANSASL 582 
WP_012858630    1 ----------------------------------------------------------------MKNTRSLFNIVLFIIF 16  
WP_046328838  109 DSQFAFIQGNRNNLDRNYASSIIGSDNKAAFSEYSNVLGHDNELNYSAFSSVNGSENKVEGLSFHSQVFGFRNKVVKGQN 188 
WP_046328839    1 --MITSVGYADTKDFVINNNIIFEKSHEKNYEKLVSRNNVIGGINNIIDDPILDIVVKNKNKKVEEIKDEISKELSNKYK 78  
WP_046328840  123 REGEKVKFNGSVDGAKLVWWNNDIEKTIKNNTIIFGRFIENDKTETKQEELHSKLSLLIDFTRDIVKESKKFLKSSDEEK 202 
WP_046328842    1 -------------------MNKKILIISLISTIISYASESQQNIPRIENGYIYITETEYNKLNENSKKLYEKVGSEYRYK 61  
WP_046328923  241 KLKEPMAGNVYDISPYYGKPQDNNIINENVKDIKAKIKTYRLPLIQSFLEAHKEFEIDKMDNCSEELYKIAFRNKVSHYN 320 
WP_046328950  224 SGVGYEVLSGENSAVVGNYAKANSNNSVVVGTYATSSNTEKAILNENGILEYAKDLVKKNKDENEYKNFKMLANREADDK 303 
WP_046328951  182 SNYSYIFGGNIQVENSNHANVQGNNNAITNSNQTTAIGENNTITNSKQTSIIGELNEVVESEKTKLLGNNNKINKSKYSY 261 
WP_046329073  119 KNEIKETDAEILKSIERTLGPNEAAKYDFEIINNIIKNVKERKLTEDDDILYKAFDSDGYYNRDVIKKVISKKNKKDEEI 198 

WP_083231440  583 GSRANASADFSVAIGNAAQATALNSVALGSGSVANRAGTVSVGTVGGERQIVNVAAGTSLTDAVNLAQLNAVASTTTANA 662 
WP_012858630   17 LTTSSIFVKGQNIIPEGLRKRSGISYEIKSVYHGIGNQNKSSISIGTKTEHGGEYSVAIGDNSSSEGYAAITQGYEAKSD 96  
WP_046328838  189 AFIHGDHNNLKNSAYSHIEGYGSEINNDDNTIDTTKNSTTKDSNYIFGDYNKILNSENSHIQGKSNEIGNSENSYIQGYA 268 
WP_046328839   79 ETGILSTIKENEKKSKGEIINIIKDKLSNIDGYDFKFIDTLIDEVKKGAQDDNKLLYSAFDPYDWYNKNKIQKVIENKDK 158 
WP_046328840  203 EKILENVEEVVKRASNNHGKSESAMQSSINECEEILKRFTEEEPKQNDTPNVNITENKFKPDFIGNIIKGNDNLVIGQGN 282 
WP_046328842   62 KNININYLNTEKNLEGVGSGITYGEGTVNQSKTSVAIGNKVKVRDNSSYSIGIGASVLVENGQNVAIGTEVYTNQYGVSI 141 
WP_046328923  321 VGKTYDELNKNVEKEKDLLNEYEGRVAYFTEWKEKFNNELKELLKSIEYKGEDNLAYGTSSYAIGIRSYAIGTNALTAGI 400 
WP_046328950  304 NIPQDKREEFIRDYIEKQIEIEAGTLANKKKIQEEFFKEYGEHTIKNEKGEEIKFFLKKNLNSPTDDYNTVIGYFSHVKG 383 
WP_046328951  262 IFGTNIQAENSNHANVQGNNNAIKDSDQTTAIGENNTITNSKQTTAIGESNEVVESEKTKLLGNNNKINNSKCSNIFGTN 341 
WP_046329073  199 KKDIATSSLYRYSDYNTILGESNKAEKSENSVVMGYLAEVENSNSHGNVAIGFYARAKGRSATAVGPRAVAVNKLAVALG 278 

WP_083231440  663 SRLTYLAVNSTQAGATATgasaislgdnatadgvdalaiggddagtgaraignstvaiggeadaiglaatafgwrsnasa 742 
WP_012858630   97 GYSSISLGYKAYAGANYA-------------------------------------------------------------- 114 
WP_046328838  269 SNIKNAANSSIIGGYFSS-------------------------------------------------------------- 286 
WP_046328839  159 EDGVIKQIVKTQSNYLDY-------------------------------------------------------------- 176 
WP_046328840  283 AVFGTNVHLGEKNKSSVN-------------------------------------------------------------- 300 
WP_046328842  142 GYDNYAGNNAVSIGGAKV-------------------------------------------------------------- 159 
WP_046328923  401 DSVTLGSNSATFGNGSNSi------------------------------------------------------------- 419 
WP_046328950  384 QKGTAVGAFSRALDNSVAlgfnakslsnnsitigdntenktnnsv---------------------------------vi 430 
WP_046328951  342 ISAKNSDFGIAIGASASL-------------------------------------------------------------- 359 
WP_046329073  279 YNARSYGENSTSIGANAM-------------------------------------------------------------- 296 

WP_083231440  743 erahalghlanatgvrslavgeaanATALTTVAVGNLasaTDEDAVAVGDLA-LASGFHATAVGge--svASGrg-aqSF 818 
WP_012858630  115 -----------------------------------------------------IAQGy---------------------- 119 
WP_046328838      --------------------------------------------------------------------------------     
WP_046328839  177 --------------------------------------------NTVLGPFSkVYNSSNSVVIGlsakaeNSGtqgniAI 212 
WP_046328840      --------------------------------------------------------------------------------     
WP_046328842  160 ----------------------------------------Tendsigignntfnsgmysialgsesinttkgsvvigpga 199 
WP_046328923  420 ---------------------------------------------------------------Gek--nyTKGdknq--- 431 
WP_046328950  431 gynasspneennkfesnvvignmtkGLGKAVVSIGNTaqsTGENSISMGNTA-QSTGENSISIGnetksiNNGi----AI 505 
WP_046328951      --------------------------------------------------------------------------------     
WP_046329073  297 ----------------------------------------------SYGNWS---------------------------- 302 

WP_083231440  819 Gwq---avASGELSLASGhqaqatgvrstavgksavasainsvaignqattnstnaaslgtsvaignlasa--------- 886 
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WP_046328838      --------------------------------------------------------------------------------     
WP_046328839  213 Gkvalatgdati-------------------------------------------------------------------- 224 
WP_046328840      --------------------------------------------------------------------------------     
WP_046328842  200 isyskksleidgnniidstkkeelykky-----------------------------------------------fdeik 232 
WP_046328923      --------------------------------------------------------------------------------     
WP_046328950  506 GnkafasnDNSSSTIAIGdeasatfnsaiaighnakagqmeisigynantykirdnidpsenitlgnyavskgsrniafg 585 
WP_046328951      --------------------------------------------------------------------------------     
WP_046329073      --------------------------------------------------------------------------------     

WP_083231440  887 ----------gdedsvaigdlanasgfhatavggesvasgrgsqtfgwqaratgelslavghQAVAGG-VRSLAL----- 950 
WP_012858630  120 --------------------------------------------------------------NAKAEG-GTSISI----- 131 
WP_046328838      --------------------------------------------------------------------------------     
WP_046328839  225 -----------------------------------------------------------sigseakalnKGAVSL----- 240 
WP_046328840      --------------------------------------------------------------------------------     
WP_046328842  233 keneivlkskireeykktnkaftekdvnqslieevrkmasfklykeysgykineegerwikrDQKADGfNTTIGFnsktl 312 
WP_046328923  432 ----------------------------------------------------------vfgvENITVG-NNNILH----- 447 
WP_046328950  586 mesrsegynsisigegafskstspekfeapsialghnaiafggsialgksatiakgkrivfkdendkenKTT-------- 657 
WP_046328951      --------------------------------------------------------------------------------     
WP_046329073  303 ------------------------------------------------------------------------TAL----- 305 

WP_083231440  951 GKSAS----------ASG--------DFGIAIGNTASAG-FMNSIAIGNGAAT--------------------------- 984 
WP_012858630  132 GSDSN----------SKR--------AFSVSIGNESKAT-SEHSVAIGSNSVTnnkvsvntvtl---------------- 176 
WP_046328838  287 --------------------------------------VnMNNSLALGAFSTTkeiknkg-------------------- 308 
WP_046328839  241 GENAK----------SLG--------KYSTAIGSQSYAy-GMNSIALGIRSIAgdaskevgyrpyn-------------- 287 
WP_046328840  301 ---------------------------NNIILGSNITNTdVNNAIVIGNGSKA--------------------------- 326 
WP_046328842  313 GKYST----------SLGafs--eayNNSVSIGLASVAT-GENSVALGNFSEA--------------------------- 352 
WP_046328923  448 GNNNE----------IYG--------ENNIVLGNEVKINkKNNAVVIGNGSEA--------------------------- 482 
WP_046328950  658 GENAEyvfssyengeIYGykkedneiMHGVAIGDYSL-TnTENGVALGSYSLSnrekgvlgyls---------------- 720 
WP_046328951  360 ---------------INA--------VNSVAIGAGSKAT-FSDSVALGSFSETklseksa-------------------- 395 
WP_046329073  306 GSNSK----------VIA--------EEGTALGYGAEVf-GEHSVALGSSSKAgeasekdgyrpysaidgkykgitqeki 366 

WP_083231440  985 --------------------------TVANQIVLG----------SA---N-HSYRFAglggNVPAGa---QfflTVDSA 1021
WP_012858630  177 ---------------geltlkdfagsNPHSVLSIG----------AT---G-KERQLQ----YVSAGqissK---STDAI 220 
WP_046328838  309 -------------------yltnqdtKDVYALAVGgeyvykddkgNEtvyK-AKRRIQ----GLADGa---E---DDEAV 358 
WP_046328839  288 -------------lneeeyknksewiADYGVVSVGgfe----klvNKl----HTRQIV----NVAAGy---N---DTDAV 336 
WP_046328840  327 ---------------------------IENAVSIG----------ND---T-TTRQIK----YVKAGt---D---DTDAV 355 
WP_046328842  353 --------------------------NERNTVSLG----------ND---R-IKRRIT----NLSEGi---N---DFDAV 382 
WP_046328923  483 ---------------------------IENAVSIG----------NE---T-TQRQLK----FVAKGt---A---DTDAV 511 
WP_046328950  721 ----------------pnnaenytwkSTYGAVSIGn--------pDK---K-ITRQLT----GLAAGs---E---DTDAV 762 
WP_046328951  396 -------------------yltdqknAPHYVVSVG----------GG---K-IKRRIQ----GLADGa---E---DDEAV 432 
WP_046329073  367 reialkegrekakeafnamfkdrvwkANLGVVSIG----------DP---RyGTRQIT----NVAAGy---Y---DTDAV 423 

WP_083231440 1022 gnimavavapatafagtgtNSTQVGngA-AASApdttavgsgavasatdatavgegaratsagatavgagaiasgstavg 1100
WP_012858630  221 -------------------NGSQLY--A--SNMimsniadsiklilggnasikdnkitidniggvgknsiheamveflkk 277 
WP_046328838  359 -------------------TVAQLK--K-VQKSiq--------------------------------------------- 371 
WP_046328839  337 -------------------NVAQLK--E-LKTYvdnstpfeyatkdnkslykygdkyyyketnkeykgkvdeviiqake- 393 
WP_046328840  356 -------------------NVSQLK--EyVKANsfsa------------------------------------------- 371 
WP_046328842  383 -------------------NIRQLK------------------------------------------------------- 388 
WP_046328923  512 -------------------NVKQLK--DyVAANsfsa------------------------------------------- 527 
WP_046328950  763 -------------------NVAQLK--E-LKNYvdyysnpfeyyskkdnkkvyrdaqgyyvieknnrkdvkaediiikav 820 
WP_046328951  433 -------------------TVAQLK--K---------------------------------------------------- 439 
WP_046329073  424 -------------------NVAQLK--E-LKTYvdnstpfeyattkgeslykygkkyyykknnkeyegkvdeviikake- 480 

WP_083231440 1101 agaqatgpgsaaygsnsratgaqsiaigedggdadglgavasgvgsiaigndalstgveavamgLSAVATAQST---TaV 1177
WP_012858630  278 neeinke------lksskdelkklsdntmiisgdkgntdtqtlskdgglkfsikgseyikteakgsEVLLDFTD---K-V 347 
WP_046328838  372 ---------------------------------------------------------------nqGANEKYIKDnyyN-K 387 
WP_046328839  394 -------------------phklsniasslgdgnttstgttpasatsengdsvvvikdlktikenKADKAYVDE---K-V 450 
WP_046328840  372 -------------------------------------------------------------------------enyyN-K 377 
WP_046328842      --------------------------------------------------------------------------------     
WP_046328923  528 ---------------------------------------------------------------enyyNKAEVDK---K-L 540 
WP_046328950  821 dklqvgnvessinpttvsqgstsdkpstkpddnndnylvvvkdlktikgnakkdkiefstfkteINNNITEIKN---D-I 896 
WP_046328951  440 -----------------------------------------------------------------------LKS---E-V 444 
WP_046329073  481 -------------------phklsniksslgdgnttssdttpasstsengdsvvvindlktikenKADKAYVDE---K-V 537 

WP_083231440 1178 GgrALATataatafgwRa-eAVAERATAlghLANASgvrstaVGEAANssgalsvavgnlsvaSGTNAIAIGNTAVaSGG 1256
WP_012858630  348 K--SDIS---------KgvaANSGVASA---VAMAN------LPQISRi-------------dDRKHNVAGAYGYY-NGE 393 
WP_046328838  388 T--EVDK---------KidfTLGGVANA---VAMAN------LPQVSG---------------DRKFNLVASYGYY-GGS 431 
WP_046328839  451 A--KLNE---------KtdlALSGVSSA---VAMAN------LPQVSG---------------DRKFNLAASYGYY-GGS 494 
WP_046328840  378 P--EVDK---------KidfVLGGVTNV---VAMAN------LPQVSG---------------DRKFNLAASYGYY-GGS 421 
WP_046328842  389 ---AVSL---------KsdiALGGVSNA---VAMAN------LPQVGG---------------DRKFNLAASYGYY-GGS 431 
WP_046328923  541 E--GINA---------KsnlALGGVANA---IAMSS------MTQPR----------------EGLVNITGAYGTY-GGE 583 
WP_046328950  897 K--EVNK---------KsdlALGGVSNA---VAIAN------LPNVSG---------------DKKFNLATSYGYY-GGS 940 
WP_046328951  445 K--GSTE---------KsdlALSGVANA---IAMAN------LVQVNSy-------------sDYRHNLSAAYGYY-GGS 490 
WP_046329073  538 A--KLNE---------KtdlALSGVSSA---VAMAN------LPQVSG---------------DRKFNLAASYGYY-GGS 581 

WP_083231440 1257 DAIAIGGnrdgtsgratqatgASTTAvGGqalatataatAYGWRAEATgerATALGhlavasgvrsvsvgeaavasgaga 1336
WP_012858630  394 HAFALGM--------------SGLNE-VG----------NVIYKVSGA---FNTKG------------------------ 421 
WP_046328838  432 HAVAVGF--------------SGTND-KQ----------NFTYKLSGA---VNSKG------------------------ 459 
WP_046328839  495 HSVVVGL--------------SGTND-KQ----------NFTYKLSGA---VNSKG------------------------ 522 
WP_046328840  422 HAVAVGF--------------SGTND-KQ----------NFTYKLSGA---VNSKG------------------------ 449 
WP_046328842  432 HAVAVGF--------------SGTND-KK----------NFTYKLSGA---VNSKG------------------------ 459 
WP_046328923  584 HALAVGI--------------SGNTE-------------RFSYKLGVS---TNMRG------------------------ 609 
WP_046328950  941 HAVAVGF--------------SGTND-NQ----------NFIYKLSGS---VNSKG------------------------ 968 
WP_046328951  491 HALAIGF--------------SGVTK-DR----------RLVYKLSGS---VNNKG------------------------ 518 
WP_046329073  582 HSVAVGL--------------SGTND-KQ----------NFTYKLSGA---VNSKG------------------------ 609 

WP_083231440 1337 iAIGNqtsaaftnSVAIGNG 1356
WP_012858630  422 -NLSL--------GAGLGYQ 432 
WP_046328838  460 -NLAL--------GIGAGVM 470 
WP_046328839  523 -NLAF--------GIGAGVM 533 
WP_046328840  450 -NLAF--------GIGAGVM 460 
WP_046328842  460 -NLAF--------GIGAGVM 470 
WP_046328923  610 -NVGV--------GLGFGMT 620 
WP_046328950  969 -NLAF--------GIGAGVM 979 
WP_046328951  519 -NLAL--------GVGAGVM 529 
WP_046329073  610 -NLAF--------GIGAGVM 620
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