Conserved Protein Domain Family
heptsyl_trn_I
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TIGR02193: heptsyl_trn_I 
lipopolysaccharide heptosyltransferase I
This family consists of examples of ADP-heptose:LPS heptosyltransferase I, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
Links
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Statistics
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PSSM-Id: 274025
Aligned: 14 rows
Threshold Bit Score: 367.817
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAP77580       2 RIAIVRLSSLGDVIVSASVLPFVKKHLEEiypqrVEIDWIVDSTFSEVLYHSPCIDNLIEINLKKGGVN---ALP-TIIK 77  Helicobacter he...
AAK03927       2 KICLVKTSSMGDILHSLPALTDAQRALPN-----LQVDWVVEESFAEIPHWHSAVRQVIPIALRRWRKTpftALTrKQWK 76  Pasteurella mul...
BAB49666       2 KVLIVKTSSMGDVIHTFPAVEDASLHRPD-----ISFDWCVEEAFAGIVALHPAIAGIHTVAIRRWRKAlfnGGTwREAA 76  Mesorhizobium l...
CAE29430       3 DILIIKTSSLGDVVHQMPAVTDAARALPG-----LRMSWVVEEAFAPLARLHPSVTEVIPVATRRWRSHlasRATwREIG 77  Rhodopseudomona...
AAQ57905       2 NVLIVRTSSMGDLIHTWPAITELKTHYPN-----IRLSWLTEESFADIARLHPQVDEVLTLSWRSWRRRlwqPSAwRELK 76  Chromobacterium...
CAA07672       4 RILIVRTSSLGDLVHMLPAISDIARYVPD-----TQIDWVAEEAFADIPKWHPAVNEVIKVAHRRWRKAwwsEPVrQERR 78  Bordetella bron...
CAC67287       3 KILIVRVSSLGDVVHNMPVIADIRRRHPD-----AQIDWLVEEGFVDLVKLVDGVRNVLPFSLRRWRKKpfsGATwREIR 77  Burkholderia ce...
CAD14222       2 RVLIVKVSSLGDVVHCTPVVADILRAHPG-----AEIDWVVEEGFAGIVRIVRGVQDVIPFALRRWRKSlasGATwGEMA 76  Ralstonia solan...
CAD17785       3 RILIVKMTSLGDVIQTLPVVTDIRRAFPG-----VEVDWAVDESCADVVRMSPGVSRVLSAPLRRFKKTr-sLADlKAIL 76  Ralstonia solan...
WP_002246566   2 KILLVRLSSMGDLIHTLPAIEDLARQCPD-----VELHWLCEAGFADIARLHPFVKKIHVMKWRQWRKHlfqAETwREMG 76  Neisseria menin...

AAP77580      78 NLKAL-P--VYDILIDMQGLIKSALCGSMLKn---KQYWGFAWDSIKEP---LASLVYTYKVRIPYEQHILERNLKLVCS 148 Helicobacter he...
AAK03927      77 TYRTLlQseQYDAVIDAQGLLKSALFATRLAr---GTRHGYDRHSIREP---IAACFYDKKYAISYQQHAVERIRQLFAQ 150 Pasteurella mul...
BAB49666      77 ALRRTlRecRFDLVIDAQGLLKSALVARQAR----APIAGFDRSSAREP---SATLFYDVTYGVPRNLHAIERTRRLFGL 149 Mesorhizobium l...
CAE29430      78 DFNTRlRepEFDKVIDTQGLIRSAIIARLAQ----GERHGYDAQSIREP---LASRFYNVHHSVSRSLHAVTRNRTLTGL 150 Rhodopseudomona...
AAQ57905      77 ALKQKlRdaRFDLVLDSQGLIKSAIPARWAG----APLAGLGWGSAREA---LASLFYDKKHKVSRKLSAIDRNRLLFGL 149 Chromobacterium...
CAA07672      79 ALAERlRsvSYDVVLDMQGLLKSAWLVRQTR----GVRHGLDWRSAREP---LASLFYNVRHRVEFWQPAVVRQRKLAAL 151 Bordetella bron...
CAC67287      78 AFRQRlAaeQYDLVIDCQGLIKTAWVASWAR----GPLVGLGNRTDGAGyewPVRFFYRKRVPIAPRTHVVERSRQLVAA 153 Burkholderia ce...
CAD14222      77 AFRRAlRakPYDVVLDTQGLIKTALVAAQARlapnGFVAGLGNRTDGAGyepLARLFYQREVHMEPRVHVVERSRRMVAE 156 Ralstonia solan...
CAD17785      77 ALAAAlRryRYDAVLDLHGVYKSAIVSFVAR-----ARRRFGYRDPDLGe-rGAMFAYNRRFGPRPACNAWHGMRISAGE 150 Ralstonia solan...
WP_002246566  77 HLKQTlRqeAFNFVLDSQGLIKSACFAKMAK----SPIYGLDKNSAREG---LAALAYAKTYAVPKGKNAVWRNRELFAQ 149 Neisseria menin...

AAP77580     149 ALGFk--dIDETNRVyyhNRAEafgVSEVDNVRVleifrafevdkdAKNIVLILESSLEAKTYPLHLFVQVIQQLleTnp 226 Helicobacter he...
AAK03927     151 SLNYpl--pHTQGDYgiaR-------HFPQHAQT------------MPYVLFFHGTTRQDKFLPDRQWRTLAEKLt-Aq- 207 Pasteurella mul...
BAB49666     150 ALGYqp--dLSTLASgivPPP----GALAGITGK--------------TAFLLHGTSREDKKWPVEDWIGTARLLv-Er- 207 Mesorhizobium l...
CAE29430     151 SLGYq---pVDEIDYgliKP------ARSGDT-P--------------YAVLLHGTSRVSKEWRAEDWIETGRWLq-Gr- 204 Rhodopseudomona...
AAQ57905     150 SFGYa---pDGPPQFgirRGER---PGWM-LSGR--------------YAVLLHATSRASKEWPEARWVELGTRLstQh- 207 Chromobacterium...
CAA07672     152 TFGYn---yAGSPDFglqAFGR---AAQADDAPAdpgrrmlhlaadRGYAVIMPSASRDDKLWPEDDWRAVFRRLq-Da- 223 Bordetella bron...
CAC67287     154 ALGDpaptPADPVDFgldTRAAalaVAALGLNLP------------VPYVVFVHATSRADKQWPDAAWIELGQALv-Rr- 219 Burkholderia ce...
CAD14222     157 ALGYav---pETIDFglqPp------ASLPFALP------------RPYVALVHATSRADKGWPQDAWVDVARALl-Ar- 213 Ralstonia solan...
CAD17785     151 ALGYmp---qgFADYgivTGRGge-rAQPGHAVG------------APYALFFHATSKDDKKWPPGHWAALAREMl-Ag- 212 Ralstonia solan...
WP_002246566 150 VFGYa---MPETQVFgltVPEA---GRLKNLAQ--------------PYYAALHATSRDSKLWPVENWRSLLQKLneEq- 208 Neisseria menin...

AAP77580     227 yLNVFLLWHSTN---KAQKIKEHFAsqk-----nvvVLPRLHMGEIKALIQKVDLLIGGDTGITHLAWAMQKDSITLYGN 298 Helicobacter he...
AAK03927     208 gIQIHVPWSNSQekqRAERIAQGLDlv--------tILPKSTLSELAQQIVNASAVVSVDTGLAHLSAALDKTNLTLYGA 279 Pasteurella mul...
BAB49666     208 gMTPVTTWSNEReksVAEAIARAVPst--------vVVPKSPLADIAAILGRSTLVIGADTGLTHLASAFGLPTVAVFLA 279 Mesorhizobium l...
CAE29430     205 gLQPVLPWGTDTerqTAERLSSAIPgs--------rVLSRQPLDLTAGVIAGATVVIGVDTGLLHLAAAYRVPLVGIYVA 276 Rhodopseudomona...
AAQ57905     208 dMVTVLPWGNDKekaRAQRLAARLPaa--------vVAPKMSLVEAAGLLGNASAVVGVDTGLVHLANALNVPVAAIYTD 279 Chromobacterium...
CAA07672     224 gCALRLLAGNEQeaeRARVLVAGMEgv--------eVLPRMDLTSVAQVLAGARLMVGLDSGLTHLSAALGRPTIGIYRA 295 Bordetella bron...
CAC67287     220 gASLVLPWGNDAeraTSERLAKEFGaa-------aiVPPKLSLPAVVGLIDGAAATVGVDTGLVHIAAALKRPTVELYNF 292 Burkholderia ce...
CAD14222     214 dYALALPWGSETerrTSEAIREAIVaavpgtlgrivIPPRMSLPDVTAFLDQSTAVVGVDTGLVHIAAAMCKPTVALYNF 293 Ralstonia solan...
CAD17785     213 gLRVLLPWHATAelrEALRIAALAPga--------aVMPRMSLAELTHKIEGAAAVVGVDTGLVHMAHAMKKPTVMIF-L 283 Ralstonia solan...
WP_002246566 209 qCNIYLPWGNEDektRAKQIADGLPfa--------iVCDKMNLLQAAYLLKHAVGIVGVDTGLLHLANALEKPVVGIYTD 280 Neisseria menin...

AAP77580     299 TPAARFALQGKNNRFLSGSEnpsyakndfsIANIQPNAICACAEEIL 345 Helicobacter hepaticus ATCC 51449
AAK03927     280 TDPKLIGSYGKNQHYLVAES----------MDKIEADEIFQKLTALL 316 Pasteurella multocida subsp. multocida str. Pm70
BAB49666     280 TEPGLTGPRGPYASTLLAVP----------GGRLTPAEVVAEADSLL 316 Mesorhizobium loti MAFF303099
CAE29430     277 TDPGLTGPVGSGPLRVLGGK----------SGGPSARQAIEAAEQLL 313 Rhodopseudomonas palustris CGA009
AAQ57905     280 TDPQQTGVVETPWATNLGNI----------GQCPTVDEALAALQTRL 316 Chromobacterium violaceum ATCC 12472
CAA07672     296 STPVRTPLVGPSYTASLGDR----------GASPSREAVLASVEQAL 332 Bordetella bronchiseptica
CAC67287     293 ATAWRTGGYWSPNVVNLGTA----------GQPPSIAQVKSALAGFG 329 Burkholderia cepacia ATCC 25416
CAD14222     294 STSWRTGGYWTPKVHDLGCA----------EAHPTSAQALDALRALG 330 Ralstonia solanacearum GMI1000
CAD17785     284 ATSRDHCGIAAPRSLSIGEQ----------GWVPGVDDVLSGLARVF 320 Ralstonia solanacearum GMI1000
WP_002246566 281 TDPIKTGVQVSPIAKNLGNI----------GQIPTADLVYQTLMDCV 317 Neisseria meningitidis
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