5K98


Conserved Protein Domain Family
HipA

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COG3550: HipA 
Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module [Signal transduction mechanisms]
Statistics
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PSSM-Id: 442771
Aligned: 469 rows
Threshold Bit Score: 122.746
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5K98_A         8 Sr--------------------PK--LVTWMn--NQ---RVG-ELTK--L-AN-------------GAHT-FKYAPEWLa 42 
WP_012969668   2 SrhadpirlqlsrgplasrqlfEK--IGVSQptgSRalkALGgEVVRfgSgRAihyalrd-earglpDIAiYRVDVE--- 75 
NP_396047      2 Rl-----------------------tLQTHFy--GQw-hHAA-TLELk-DdAAgf----------qGASI-VDYDLDYFv 42 
WP_014293390   2 Vt-------------------pLTltIQIFHh--GQw-hDAA-ELTIe-KpHLgr----------sGPVR-LGYEFDYAl 46 
WP_047854433   2 DaleqmlgmlarlgeaqakdlaQE--LGVSQptvSRligAAGdRVCRmgQtRAtryartralpgigTRLPiYRVHET--- 76 
WP_000737056   1 ---------------------mKKltIQALLn--KNw-iDIA-ELKLl-EpKLgs----------aSASE-LEYELDYAi 43 
WP_067968740   2 Mi-----------------------tLQTYLg--DRw-fDAA-EVSFe-QpDAgy---------iaG-AT-VCYDVDYFa 42 
WP_064121355   2 Al-----------------------tIQAHHh--GRw-hDAA-QLMVd-DpSRgr----------aGPAR-LEYDPLYAc 42 
WP_095849049   2 PtrsdtirqllsqgpmparqliER--LSISQptmSRalrVLGdDVVRigAgPSiqyalr-dtyrgfRSAPiYRITDE--- 75 
WP_130538108   1 ----------------------MKitLQVFHn--QKw-hDAA-ELKAd-TpSQ--------------NVS-LDYLKPYKi 38 
5K98_A        43 -------------SRyArPLSLSL-PlQ---------RG--NItsDAVFNFFDNLLPDSPIvRDRIVKRYHA-------- 89 
WP_012969668  76 -------------GQ-IrrLG-MLiPvRpegfvmrqeNGaahh-sdgLPWWLLDMRPQGYL-GRAYAVRYGAelglpgsl 138
NP_396047     43 tvasaefaggktvRD-HrALSVRY-PvDl---------EnrYS--RSWPPFLLDLMPQGHA-RRKLAEHLSLae------ 102
WP_014293390  47 ky--------qyrDD-EyACGLTL-PvEl--------mIphDA--TTWFGFLDDIMPAGAA-RRYWVNLLGLsh------ 99 
WP_047854433  77 -------------GK-VePFE-ALhLlDggrhwlsatDGrgtl-fegLPPFASDMSPQGYI-GRTFS-ARNPelelpsrl 138
WP_000737056  44 qy--------ldrRD-EhACSLSL-PvQi--------lIkhES--DTWFGFLDDIVPSGAA-RRYWVNYLDLqr------ 96 
WP_067968740  43 ekgavefaddrpvTD-FrAVSFKY-PlSl---------AdkRT--SRWPPFLLDLLPQGHA-RIRLAKALGLpp------ 102
WP_064121355  43 dw--------lghDD-LpACSLRL-PvElil--------vhRS--PHWFGFLDDIMPSGAG-RRFWIAYLGLtn------ 95 
WP_095849049  76 -------------GR-ItSLG-ELiPvRpngfvmmqtDNvsly-sdgLPWWLFDMRPQGYL-GRAYASAYAAelglpanp 138
WP_130538108  39 df--------lfeRL-EtACSVNY-PvEi--------fQtyQK--QGWFGFIEDILPAGSS-RRYWIRRLGLeg------ 91 
5K98_A        90 ---KSRQPFDLLSEIGRDSVGAVTLIPED-E----TVThPIMawe---klTearlEEvlTAYKadiplGMIR-EEND--- 154
WP_012969668 139 sdwTDTHALRALLVHGHDVVGNLLLGEMArErflsAPP-Ptp-------vPmaekA---GHY------VQLAaEAARgdt 201
NP_396047    103 --gSRASDLPLLLRSATGGIGNIRIKEAA-E----AET-ERLrgverqgvTeaeiLErsDRFMev--aDRFG-MLAS--- 168
WP_014293390 100 -atPEKQDTELLHHGTIAPVGNLRIKES-------LPVlpanstlkqrrfAigevVErnTDFLey--aQQMG-AASG--- 165
WP_047854433 139 gdwSDDDRLIALARRGEDCVGHLILGEESlNrwl-------------astSeptdR---TAW------PDLArRSARe-q 195
WP_000737056  97 -ltYAEQESILLEKGGMAPVGNLRIKEA-------LPPlnpestlhlryfSkedvAErnIDFLey--aQQMG-AISG--- 162
WP_067968740 103 --dSRASDLPLLMRSGGSTIGNVRIKEAA-E----QEA-KRLqgivrmglAlhdiLDrtDLFVev--vDNHA-MIAS--- 168
WP_064121355  96 -lePHQQDYELLSRGTIAPVGNLRIAQA-------VPEqast-----qrfGlnevVErdTDFLey--aQMHG-AASG--- 156
WP_095849049 139 dewADADVVRALLAHGHDAIGNLLIGEQArDrflaMPE-Ptpv----------erA---TTY------PALAlAAGAgea 198
WP_130538108  92 -vaRWKQDIILLQQATIAPIGNLRVKEA-------VPEkfaddl-qerrfSvsdvVEhnIDFLey--aQEMG-AMSG--- 156
5K98_A       155 FRISVAGAQEKTALLRI-GNDwc----iPK-GITPTTHIIKLPIGEirqpnatldLSQSVDNEYYCLLLAKELGLNVPDA 228
WP_012969668 202 PGSSAGGEQPKFTTFAE-T---------PD---GPRHVIVKFTEPVdglv--serWSDLLLAEHLALETLREAGVAAART 266
NP_396047    169 GSSGLQGEWPKVSMTQAkDGLyypdsfvTD-DEAVRHVIVKLVRSNep------vdRLILEGEALYSRIAQEIGLNVHEP 241
WP_014293390 166 GATGAGGEAPKLLLRCSdKDEvwidtfqDDvHTPDTHYLVKFPRNNrgt-----idCDILRAEYHYYHELHSLGISTIST 240
WP_047854433 196 MGSSAGGEHPKFLTYSG-G----------------RHVLVKFVSDDegav--arrWRELLVCESLALEVVHVAGLDAARA 256
WP_000737056 163 GATGAGGEAPKLLIRVSpEQKvwidtyqEQfDQPDQHYLVKFPRNNrse-----idCDILRAEYYYYQILNELGFNTIET 237
WP_067968740 169 GSSGLQGEWPKVALTLAkDGLyypdplvAD-DEAVKHIIVKLKRGGdi-------dGLILKTEAVYSQVAARIGLHVHAP 240
WP_064121355 157 GATGAGGEAPKLLLRRDdHERiwidarqDDdICLDRHYLVKFPRGArgt-----idADILRTEYHYYQELNSLGIETIAT 231
WP_095849049 199 PGSSAGGEQPKFCTYTE-R----------------GHVLVKFSAPDdnpv--serWRDLLLAEHLALRML------GVET 253
WP_130538108 157 GATGAAGEAPKLLVRRNgE-SvwidtyqDNlTNLDQHYLVKFPRGKgll-----rdQQILEAEYAYIKELNRLGFSAIDA 230
5K98_A       229 EIIKA-GN-V-RALAVERFDRRWNa-E--RtvllRLPQEDMCQTFGLPSSVKyeSdggPGIARIMAFLMGSS-Ea----- 296
WP_012969668 267 RVIDH-GQ-Q-RFLEVERFDRVGAa-G-------RRAIISLGAFDAEfvg-----sgrDRWPIVVRRLSASGeIr----- 325
NP_396047    242 STYA-----E-SVLIIPRFDRKKKegGgtV----RLGQESLVSAIGVA---Df-Ghv-gSHEAYIDVLRQYSaNp----- 301
WP_014293390 241 TGMKLlEGeRfPSLWLPRFDVAMRe-GelT----RYGLESVYSVLHKAPGSy------lKHQEALRCLVKLLeQqyrvve 309
WP_047854433 257 RWFDE-RG-F-RFLEVERFDRVGAr-G-------RRGVVSLEALDHEylgd---sgrgASWTRVTPKLLEKKlIg----- 317
WP_000737056 238 TQMQLiEGtKyPSLWLPRFDTEWCd-QywH----RYGLESVYSVLNKSSGSh------lNHFEVIEDLCRLLtSidsd-- 304
WP_067968740 241 STA----G-N-GTMIIPRFDRYVDerGrtA----RVGQESMTSAVGVS---Df-Ghv-dAHERYVGIVKAYSaDp----- 300
WP_064121355 232 EGMELrEGtRyPSLWLPRFDVGERe-GrlE----RYGLESIYSLLDRGPGEy------lNQFTVIRTLARLLaQrehdq- 299
WP_095849049 254 EVFDF-GG-Q-RFLEVPRFDRVDQl-G-------RIGVFSLRALDAEfvg-----narASWPVLVKNLITQGhVh----- 312
WP_130538108 231 SKTHLqKQgDqISLWLPRFDVSYDk-GyvE----HYGLESMYSILEKPAGSl------lNHFDVIQSICEKLqElngf-- 297
5K98_A       297 -------lKDRYDFMKFQVFQWLIGATQGHAKNFSVFIQAGGSYRLTPFYDIISAFPvlggtgiHis------dLK---L 360
WP_012969668 326 -------sEAADEADLLWAFGTLIGNTDMHLYNLSFVSEHGRPYGIAPAYDMSPMCF-------AprsgggmadTIq-kA 390
NP_396047    302 -------fADIVEYLKRDIANLALGNPDNHGRNSALSKHQDGTIRLSPLFDFAPMRI-------Akegi--vrsTRw--A 363
WP_014293390 310 leesfdrqAFVIEWIKRDLLNVAFGNSDNHGRNTALLKKP-AGIWLAPVYDFAPMKA-------Dpemv--prsTIwgsP 379
WP_047854433 318 -------pEDARRLRWLDVFGQLIGNTDRHFGNVSFLEQGAGTLRLAPAYDMLPMLF-------ApsgttvvdrPFe-pA 382
WP_000737056 305 ----fdvpQFICEWLQRDLLNIIFGNSDNHGRNTSFIKKS-GKIYLSPIYDFAPMKA-------Dpevv--trsTTwgsP 370
WP_067968740 301 -------qADVLEYLKRDATNIAMGNPDNHGRNTAMSKYPDGAVSLSPLYDFAPMKL-------Addvi--arsTKw--R 362
WP_064121355 300 ---gfdqaGFTIEWVKRDLLNIAFGNADNHGRNSALIKRP-EGVTLAPVYDFAPMRA-------Dpegi--vrtTTwgqP 366
WP_095849049 313 -------pEAAAGSARLWAFGALIGNTDMHHGNLSFISRHGRPYHLAPAYDILPMGF-------AprtggaivnELr-pA 377
WP_130538108 298 -----nanEFTKEWVKRDFLNVMFANSDNHGRNHAFLKKH-GKIELAPIYDFAPMKA-------Dleqi--vrsIKwg-r 361
5K98_A       361 AMGLNASkgkktaidkIY-PRHF---LAT-AKVL---RF-PEVQMHeILSDFARM--IpAALDNVKTSLPtdFPENVVTa 429
WP_012969668 391 TIHSD-----------VS-NETW---RL--Ag-----QL-----ARdFLARIQRQsvFsRRFDPCL--------HSLTQh 435
NP_396047    364 MMRDGGR-------------DHLpdwKRIcAELIp--DPdEQNALAaELSVFAEYl---rQTPAMAKDMG--GSPEILEr 423
WP_014293390 380 -LEEGGQ-------------YNW---QTI-AAELa--DLaEPEQVLkELKALAGKl---vGLKQRLKARG--VPESILNm 434
WP_047854433 383 P-PSA-----------DT-LDVW---AD--Aa-----RH-----AHvFWTRVIECaaLgEELRALA--------QQCRTa 426
WP_000737056 371 -YEEGGE-------------YRW---AQI-TQKLa--PWcDPDLSLaTLRTLANNl---lGLKQRLVDKG--VPKQIIEm 425
WP_067968740 363 CMEGQGS----------DyAPDW---SRVc-DAVsgdGV-DGAALAeGLVAFADAl---eAAPAIAiEEG--ALAEAVHq 422
WP_064121355 367 -FESGGR-------------FDW---HAI-AAELv--DLvEPERLLdALGRLARQl---vGLRDRLETRG--VPSSILDm 421
WP_095849049 378 SLPEV-----------IS-GDTW---RE--Al-----NL-----AEnFFAIASGCdrFsARFAPCL--------EALHRh 422
WP_130538108 362 pYESGGD-------------FDW---KGI-TQQLk--EHiQPTELWqELQALAAEl---vGLKERLLDYG--VNAEFLEi 417
5K98_A       430 v---esNVLR 436
WP_012969668 436 i----eAASV 441
NP_396047    424 aigrciEIAE 433
WP_014293390 435 pvmgfdYLDN 444
WP_047854433 427 l----eALRE 432
WP_000737056 426 palsfdYIEA 435
WP_067968740 423 atarcsDVVE 432
WP_064121355 422 pnvglgNLDQ 431
WP_095849049 423 l----dEARS 428
WP_130538108 418 pvlgmnSIES 427
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