6WN6,5B80,2HK0,1I60,3JU2,3NGF,1K77,5ZHZ,2X7V,9XIM,2ZDS


Conserved Protein Domain Family
AP_endonuc_2

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pfam01261: AP_endonuc_2 
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Xylose isomerase-like TIM barrel
This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.
Statistics
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PSSM-Id: 426164
Aligned: 163 rows
Threshold Bit Score: 83.5741
Created: 21-Mar-2022
Updated: 13-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6WN6_B  71 FRYIK----EM-G--FDGFE---------IDGKLLVNNi------EEVKAAIKETGLP--VT--TACGGYDg-------w 117 Escherichia coli
Q82UC3 486 RALIE----GM-K--IDFVE---------FHLSYHDLDv------KLSDYFSDPLSIG--YA--VHSPELFagdh--ild 537 Nitrosomonas europaea
Q8F5Q4 489 EQILS----KV-E--MDLVE---------FHFSYKDLK-------VEISEYIKKP-LNtdFV--VHCPELFendh--lld 540 Leptospira interrogans
Q98PU8  20 IKESI----KN-G--ANCAMiflgapqntKRVDFEKYQyek--ylKDFSNLIKPED----IV--VHAPYII--------- 75  Mycoplasmopsis pulmon...
Q65202  29 VAFGE----QI-GfpFKSAQvfia-gprkAVINIQEDDk------VELLKMIVKHNLW--VV--AHGTYLDvpw------ 86  African swine fever v...
Q8TH64  24 LE-------DH-G--YTGWE---------IVQEGSQCLssk--tvQNLKNIYETTNLE--LT--LHLPFSDm-------n 71  Methanosarcina acetiv...
Q7CSS9  42 LHALA----DI-G--CDTVEiavtsldliAGGRIIEERa------ERFVALAKQFGFR--YT-------VHgl-----vs 94  Agrobacterium fabrum ...
Q8TTZ8  12 LPELK----ES----VGSIElyipklgiyTGSVLEKKEl------ERILDEMSTYCFA--GT--VHAPYFAadp----ry 69  Methanosarcina acetiv...
Q8U245  20 LDELNvdfvEL-G--FDDAE---------IIKNDGEIN-------MKILKDLSGLGIE--FT--IHAPTSDgknfpidfg 76  Pyrococcus furiosus
Q8A8Y6  53 FQLVH----ELkG---DGVEldm---gslGKREMFDNKlrephfqQLFRETAQNYNLE--VPsiAMSGFYGqsf------ 114 Bacteroides thetaiota...
6WN6_B 118 IGDfie---errLNGL-KQIERILEALAEVGgKGIVVpaawgmftfrLPPMT---SP-RSLDGDRK-MVSDSLRVLEQVA 188 Escherichia coli
Q82UC3 538 LAShda---dyqAHSI-AELKRTVAVAAELR-QYFPAtpkpv-lvlnAGGWTp--QN-FLPVEART-KLYDKVAKALDEI 607 Nitrosomonas europaea
Q8F5Q4 541 LCTede---dyrKRSL-IEIQKVIDITRRLK-DFFPNsnkkpfivtnVGGFS---LN-KPLDTTIReKLYKNLSRSLNDL 611 Leptospira interrogans
Q98PU8  76 --Npasl--ekaDFAI-SFLSSEIKRMDKAKfKYLVL----------HPGFY---GK-NNVKDSLD-QLARSIQKIFEIT 135 Mycoplasmopsis pulmon...
Q65202  87 ---------srrSAFVtHFIQQELLICKEVGiKGLVL----------HLGAV-------EPE-----LIVEGLKKI--KP 133 African swine fever v...
Q8TH64  72 LAGlnd---sirAEVL-RQMKNYLTLASNYV-NLAVV----------HPGYLs-pYGvQVPDQAYM-TNLASIRELCDFA 134 Methanosarcina acetiv...
Q7CSS9  95 SNFmdp---vtcRYQI-DAAKALAVLCDRIG-AGILVq---------HSGALradQI-AERADADA-REREALFELAEFC 158 Agrobacterium fabrum ...
Q8TTZ8  70 PAAlqvntakmgNREF-TLLEESMTIANRIG-AHVVVl---------HPGRIg-----PDREKSFA-SMVKNLSFLASRA 132 Methanosarcina acetiv...
Q8U245  77 EYFpidl-gtyrKTPIiKRMKKIIKVAEYLD-ASVIV----------VHGGD---IK-ESYTKAYV-NTLRNLRELKPIT 139 Pyrococcus furiosus
Q8A8Y6 115 ---------ldrANYK-ELVRDCLDAMKVMG-AKVAFl--------pLGGVEa-gWQ-ETPE-LRT-ALIKRLKEVGDMA 171 Bacteroides thetaiota...
6WN6_B 189 ARTgTVVYLEPLnRYQDHmi--------nTLADA-RRYIVEND-L--KHVQIIGD------FYHMN---IE-Ednl---- 242 Escherichia coli
Q82UC3 608 DLStvQLAIQTMpPFPWHfggqshhnlfvDPDEI-AAFCDKTG------HRICLD------ISHSMmacNY-Yqwdfn-- 671 Nitrosomonas europaea
Q8F5Q4 612 DSEgVEIIPQTMpPFPWLfggqryhnlflSAEEI-VEFCKRH--S----IRICLDvshsklACNHY---HW-Sfskfv-- 678 Leptospira interrogans
Q98PU8 136 KDSnVEIMLETMsGKGSEvg--------kSYEEI-LYVIDKVK-S--PRLGACLD------TCHVW---DA-Gynindyq 193 Mycoplasmopsis pulmon...
Q65202 134 VEg-VVIYLETPhNKHHTyk-------ysTMEQI-KELFLRIRnTrlKQIGLCID------TAHIW------Ssgvniss 192 African swine fever v...
Q8TH64 135 ADFgIIVAVENMpDFPKIfg--------kYPDEM-QEMLDAVG-S--HNVGFTFD------VGHAN---TVrli------ 187 Methanosarcina acetiv...
Q7CSS9 159 KPYgVRIALENI--FSTEpgq-----yrqTPTEV-AATVKALG-H--DNVVALID------FSHAYlesTY-Rgldfr-- 218 Agrobacterium fabrum ...
Q8TTZ8 133 EDHgVVLGLENKeGTDPSnf-------ccEAEEL-AGAIEIVN-S--DHLKATFD------IGHAN---LTcGgdsg--- 189 Methanosarcina acetiv...
Q8U245 140 EDSgVKIVVENLfe--------------gRIGALpHEVLSFA--K--EGFEVCFD------IGHAFltaIRtGlrvd--- 192 Pyrococcus furiosus
Q8A8Y6 172 ASErVVIGIETQl----------------DAREE-VKLLKEIN-S--PGIKIYFK------FQNAL---EN-Grdlc--- 218 Bacteroides thetaiota...
6WN6_B 243 -----------aqALHDnrDLLGHVHIAD-----------------------NHRYQPGSG-TLDFHALFEQLRADN-YQ 286 Escherichia coli
Q82UC3 672 ---------tflqKVLP--Y-TIHLHIVDakg------------------vdGEGVQIGHGdV-DFTLLRDQLNQFA--R 718 Nitrosomonas europaea
Q8F5Q4 679 ---------------eqvsPYVAHLHIVDakgvd------------------geglQIGEGeI-DFHMLSNILREKT--P 722 Leptospira interrogans
Q98PU8 194 v-----fkdelikTGIL--KHIKVIHLNDsknel--------------gshkDRHANIDKG-LIGLKNLKRIVHDPI-FE 250 Mycoplasmopsis pulmon...
Q65202 193 yndagqwlrslenIHSVipPSHIMFHLNDaatec--------------gsgiDRHASLFEG-M-IWKSYSHKIKKSGlY- 255 African swine fever v...
Q8TH64 188 -----------deFLDQlkDRISHVHIHDnmg------------------kkDEHLPLGEG-NIDWKHVMEKL--SN-YK 234 Methanosarcina acetiv...
Q7CSS9 219 ---------aelrAMAP--V-AGHLHVHDsfgrpqgfyepyfpqestalgigDLHMPLGWGdI-DWQDIFSELTFLP--D 283 Agrobacterium fabrum ...
Q8TTZ8 190 ---------klrtFVRTlqKHIIHLHLHDnsgswt------------ekydgDEHMAPGKG-CADF-SVLKLL--SG-YR 243 Methanosarcina acetiv...
Q8U245 193 ---------efemLF----PYTTHLHLHDnng------------------frDEHKPIGEG-IIGFSYVERVLELTN--P 238 Pyrococcus furiosus
Q8A8Y6 219 ---------kelkILGK--NRICQIHCTDt---------------------dGVTLPFNE--RLDMNKVKKTLDKMG-WR 263 Bacteroides thetaiota...
6WN6_B 287 GY-VVYEGRIRAe---DPAQAYRDSLAWLRTC 314 Escherichia coli
Q82UC3 719 GVqFIPEIW-------QGHKNKGEGF-WSALA 742 Nitrosomonas europaea
Q8F5Q4 723 KAsFIPEIW-------QGHKNNGEG--FLISL 745 Leptospira interrogans
Q98PU8 251 NIpIILETPWT-----EKGPIYDQEIAMLLEK 277 Mycoplasmopsis pulmonis UAB CTIP
Q65202 256 ---CFVEYITRHqcpaILERNLGSSMQLQTAL 284 African swine fever virus BA71V
Q8TH64 235 GI-FVTEM--------ASVEGGIKSLEFLRKL 257 Methanosarcina acetivorans
Q7CSS9 284 TV-LMME-IGRRyr-aEQPASLE-TARHLMSL 311 Agrobacterium fabrum str. C58
Q8TTZ8 244 GI-YNLEVF------------SLEDVKFGKQI 262 Methanosarcina acetivorans
Q8U245 239 ER-AVLEIRRY-----NKENSVLLNVEVLQEI 264 Pyrococcus furiosus
Q8A8Y6 264 GW-LVVERSRDKddvrNVKKNYGTNIEYLKKV 294 Bacteroides thetaiotaomicron
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