Conserved Protein Domain Family
AslA

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COG3119: AslA 
Arylsulfatase A or related enzyme, AlkP superfamily [Inorganic ion transport and metabolism]
Statistics
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PSSM-Id: 442353
Aligned: 801 rows
Threshold Bit Score: 124.22
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_085754083   3 LRRHRfrkta--lglvaLSLALqgcggsdddtvatT--PPPATLAKRPNILFIMADDLGYSDVGAfgg-eisTPHLdala 77 
NP_812013      1 MNRLFls--------vsVALSAt------------T--CSFAQQITQPNLVLFIADDCSYYDLGCygsvdskTPNIdnfa 58 
WP_076699889   1 MNKKQqvllv--lgfsvLVLTScignkgre-hkdlakvESETQTNPSPNIIFYLADDQDVYDYGCygndkvnTAAVdrla 77 
WP_013667550   6 LRTNFisvrilnallllALLVAclq--------raQ--AALPNKDEKPNIIIIMADDLDSKQLSCyggvnikTKYIdqla 75 
WP_102996280   1 MFSKKigvii--fgciaLIHLNcsgnkkaq-evsgtkiEKLSTINKNPNIIFYLADDQDVYDYGCygnekvhTPAVdala 77 
WP_013630607   1 MKRSFfiha----allfVLIVSstsae----vpakAnrSAADNSTSSYNVLFILLEDQGA-QLGRygtaglkTPHMdaia 71 
WP_038555186   1 MTKTSrycf-----illLILLGfh------------lyASDVNRKGQPNILIVIADDCTHSDLSLyggqnvkTPHIdqla 63 
WP_110172312  10 MRVRSsrlvf--vaawiLSLAL-------------A--VSAAAQTRPPDIVVFISDDHGVLDSTVygsrdvkTPSMdrla 72 
WP_077023658   1 MRHFNa----------aAVLHClhl--------vcS--AATCSASDKPNILFMIADDCTFRDIGCygg-qahTPNIdkla 59 
WP_095414025   1 MRAAvm---------wlVCLGAglw--------glA--SRAAEPSQRPNFLIIMADDCTYNDLPVyggknafTPNIdrla 61 
WP_085754083  78 aSGRLLTNHHT-GTVCAITRSMLISGTDHHLVGEGTMGapnderrg---------lpgyegyLNDRSLSVAQLLKDAGYH 147
NP_812013     59 tQGVRFTQAYQaAPMSSPTRHNLYTGLWPVGSGAYPNHt----------------------cADQGTLSVVHHLHPLGYK 116
WP_076699889  78 nEGMLFTNAFTgQAICAPSRSQLFTGKYPLKNGCFANHt----------------------aTKPDVKSVTSHMKDLGYE 135
WP_013667550  76 sEGMKFNTLVAsEAMCVPTRASLFTGLYPARHGAYQNHk----------------------qVYPELKSIIHYLNAVGYR 133
WP_102996280  78 nEGIIFNNAFTaQAICAPSRSQLFTGKYPLKNGCFANHt----------------------aTKPDIESVTAHMKKLGYE 135
WP_013630607  72 aSGADFRKAFVpYPVCSASKAAIMTGLHNHTNGLLNNTanyhkppqqltadernrpvyvnnrIRSHLPTLTERLHEAGYY 151
WP_038555186  64 sQGMTFNNAFVtMSMCVPCRAELYTGLQPVNSGVCWNHa----------------------iARTGTQSIVQYLGELNYR 121
WP_110172312  73 kAGLTFDRAFVaSPSCAPSRAALLTGLMPARNGAEANHs----------------------kPRPDLQTLPAYLQALGYE 130
WP_077023658  60 tEGMRFTRCFQsAPMCSPTRHNIYTGLYPVTSGAYPNHt----------------------fVPDGTKSVVQYLSKLGYR 117
WP_095414025  62 rEGLVFDRAYLsMAMCQPCRAELYTGLYPMRNGCCWNHs----------------------aSRPGIRSLAHYLSALGYR 119
WP_085754083 148 TYMAGKWHLgsniatpatpvplgtaghtpdqwgfeksfalmggaasnhyfhetatsknytengayiqpgqpgqpgtgsYS 227
NP_812013    117 VALIGKKHVapksvfp-------------------------------------------------------fdlyvpsEK 141
WP_076699889 136 VVLAGKSHVkpesvyqwdk--------------------------------------------------ewepvpkkdVP 165
WP_013667550 134 VGLAGKDHVtkpvsifpfdr------------------------------------------------vggfepncvsQT 165
WP_102996280 136 VVLAGKSHVkpesvyqwdr--------------------------------------------------ewepvpkqgVP 165
WP_013630607 152 QGVSHKLHLspsek-----------------------------------------------------------fpydeYL 172
WP_038555186 122 VGIAGKVHAdprevypfem-------------------------------------------------vegverncvsET 152
WP_110172312 131 VVAFGKVAHykyaadyg-----------------------------------------------------fdyfahdtFH 157
WP_077023658 118 VAQSGKTHVapnsvfd--------------------------------------------------------wekipgPK 141
WP_095414025 120 TGLAGKVHVepktvfpfedv------------------------------------------------pgfcpnctadPT 151
WP_085754083 228 TDFY-TQRLISYIDANKGDGKPFFAYAAYTSPHWPL-QV--PEPWLS-KykgryDagyeairaarIAkqkqlgiIP--Qd 300
NP_812013    142 GELH-FEAIQKFIADCKRKGQPFCLFVASNQPHTPW-NK--GD--VS-Qfd-pdK----------LT-------LA--Pm 194
WP_076699889 166 RDYIpLDSIEAYFK---TSKKPFCMFITSKYPHGKYfDVenPna---------nD----------IKf------YPfnEh 217
WP_013667550 166 DNYT-LDSVRSYI----KQEDPFCLFVMSINPHAPW-TV--GD--PT-Efd-psK----------LK-------LP--Ph 214
WP_102996280 166 RDYIpLDSMAAYLK---NAKKPFCMFITSKYPHSKYfDVenPka---------eD----------IKf------YPfnEn 217
WP_013630607 173 KHTN-GKAVTEFINR--AEDQPWFLLYNISRPHRPF-PN--SDRE-SiRvn-pdE----------VE-------LP--Ef 225
WP_038555186 153 ANYD-PAGLKEFMA--RDKEQPFCLITALVVPHIPW-TV--GD--PS-Hfn-peE----------LK-------LP--Sy 203
WP_110172312 158 DDVA-IARGIAWLRQR-KPGKPLCILFGTNWPHVPW-----PE--ADggd-vvtS----------LR-------LP--Ks 208
WP_077023658 142 NPq--FDKVDAFLGDSAKSKTPFCLLLCSNEPHTPW-NQ--Gdp---sRyp-peK----------IT-------LP--Ph 193
WP_095414025 152 PPHN-VEGIREFMT--RKNDQPFCLIVALVEPHVPW-VM--GD--RS-Ryp-vrN----------LK-------LP--Ph 202
WP_085754083 301 ftpYATdpetltsspasanngtasakyinavngpadgyvdhgagrvskkwdsltALEKKAQARYMEIYAGMVENLDHNIG 380
NP_812013    195 ---YVD---------------------------------------------------VPQTRQEFTKYLAEVNFMDQEFG 220
WP_076699889 218 ------------------------------------------------------KKNDKAYvKAKAGYYRSIEEDNTQIE 243
WP_013667550 215 ---WVD---------------------------------------------------TDLTRRQFCNYLAEIRRLDNQVG 240
WP_102996280 218 ------------------------------------------------------KKTDKAFiKTKAGYYRSIEEDNRQLE 243
WP_013630607 226 ---LAD---------------------------------------------------TPVIRKDWAEYLEAIERADALVG 251
WP_038555186 204 ---LAD---------------------------------------------------NKETRREFAKYLAEIEVLDQQVG 229
WP_110172312 209 ---HVD---------------------------------------------------TRQTREMRAKYYAAVSRMDTELG 234
WP_077023658 194 ---FVD---------------------------------------------------TPETRDGMSRYMAEITYYDSQVG 219
WP_095414025 203 ---IAD---------------------------------------------------TPKTREDFAAYLAEITYMDSQVG 228
WP_085754083 381 VLIQHLKDIGEYENTLIVFQSDNGAEGWpiasastdpkatdeanaadavyatlgtdngltsakrlqygirwaEvsatpfr 460
NP_812013    221 NVLSILEQEKVADQSVVVYLSEQGNSLP---------------------------------------------------- 248
WP_076699889 244 KVLDLVDTY-LDDNTLFIYSADHGVS------------------------------------------------------ 268
WP_013667550 241 DIINVLKETGKEDNTIVIFLGEQGPQFP---------------------------------------------------- 268
WP_102996280 244 EVLKLVDTY-LTDNTLFIYSADHGVS------------------------------------------------------ 268
WP_013630607 252 EAMAALKASDEEDRTIVILLSDHGYCFQ--------------------------------------------H------- 280
WP_038555186 230 ETIALLDELKISDNTIVIFTSEQGAQLP---------------------------------------------------- 257
WP_110172312 235 EVYDAARAV-LGPDTFFLFSADHGAQWP---------------------------------------------------- 261
WP_077023658 220 KALQLLEKHRLADNTLVVVVSEQGSSMP---------------------------------------------------- 247
WP_095414025 229 DILRVLDEAGLRDSTLVLFTSEQGAQFP---------------------------------------------------- 256
WP_085754083 461 QTKGHFGEGGVGTPLIVRMPHQAKAAGNFTSFTHIVDLTATFLDAGQAKLPT--Eaappsinaitgvdqnkgkvvydsry 538
NP_812013    249 FAKWTCYDAGVHSACIVRWPGVVKPGSVSDALVEYVDIVPTFVDIAGGKPQT--R------------------------- 301
WP_076699889 269 -GKFTVKDIGLKVPFVARWPKVIKPGSTSNQLIHYTDVLPTFMAIAGRQAPN--D------------------------- 320
WP_013667550 269 GGKWTLYDNGQKSSMIVKWPGEVDAGTKTDAIVQYEDIMPTLLDIAGGKSIK--A------------------------- 321
WP_102996280 269 -GKFTVKDIGLKVPFVARWPKVIKPGTTTNQLIHYTDVLPTFMEIAGGKSPE--D------------------------- 320
WP_013630607 281 -GKMSLYEAGLHVPLAIRVPEY--PTFVSNALVSSLDLFPTLVDLLDLPELE--E------------------------- 330
WP_038555186 258 FCKWTNWNNGVHTGFIVRWPGKVNSGSRTDALVQYNDVLPTLLDALGNTSDT--D------------------------- 310
WP_110172312 262 FAKWTLYDAGIRTPMIAVWPGKVAAAARSDAMVSWVDLLPTLIEVGGGQAPP--R------------------------- 314
WP_077023658 248 FAKWTCYDNGLQSALIARWPGRIKPGSVNPAMIEYVDLLPTFVEVAGGKPDA--A------------------------- 300
WP_095414025 257 GCKWTNWNLGVHTALIARWPGHVPAGRRTAALVQYADVAPTLIELAGGNPADfgP------------------------- 311
WP_085754083 539 vypVTGQSLLQVllGNssasvRkAP-FAdESY-----------G-RAyVtsTDGKWKALWTEPphg-------------- 591
NP_812013    302 ---VDGESFKSVltGKkk-ehK-KYsFS-LQTsrginkgpeyyGiRS-A--YDGRYRYIVNLTpeatfqnamtatplfke 372
WP_076699889 321 ---IDGNSFLPLlqGEdv-evN-KYvYG-VRTnqnil-nsevfPsRM-I--RDKRYKYIRNFNsievvnqnltgkan--- 387
WP_013667550 322 ---LDGFSFKQVllNKas-thR-DFaYG-IHNnipe---gpayPiRS-I--RDLHYKYIRNLLpdstyyikymmntdkdn 389
WP_102996280 321 ---VDGNSFLPLlqGKdv-evN-NYvYG-VRTnqnil-nseifPsRM-I--RDKRYKYIRNFNsievveqnltgkph--- 387
WP_013630607 331 ---SHGISLIGQlqQRpeaktR-DCiFG-EIShrgpl-pnpgmQeRS-V--RDDRWKLIYREKvqtnwrqvnadlkdpqp 401
WP_038555186 311 ---FDGSSFLPVllGEke-thR-EYaYF-MHNnvpe---gpayPiRS-V--TDGNYHYIRNLSpkslyierhlmarmpln 378
WP_110172312 315 ---LDGRSFAGVllGRtt-thR-DRiFT-THTsdpp---mnvyPmRS-V--RTTDWKYIRNLQpsrtftthidrgkpvdg 382
WP_077023658 301 ---LQGKSLLPVlaGQqd--hK-SHvFG-IMTtrginsgsdhyGiRS-I--RSEKFKYIWNLTpdvkfqnacttspefqs 370
WP_095414025 312 ---LDGTSFREVllGLkd-ehR-RYaYF-AHNnfpe---gppyPiRS-V--TDGEWHYIRNLTpqevyiekhvmgqlgga 379
WP_085754083 592 ---------------------------paD-G----HWQLYDLTKDRGENNDLSATnP---DVLKGLVTDWKTYMTSVG 635
NP_812013    373 wk---------qlaetdahakamtfkyqhR-P----AIELYDVRNDPFCMNNLAGD-TkysNIIIRLDAELKKWMKACG 436
WP_076699889 388 ---------------vdyfikrganahknE-P----LEELYDLQNDPFEQNNLAKN-PelnSIKENLKKAMFSWMKSQG 445
WP_013667550 390 lawt----swvrkaendksavplieriahR-P----AVELYDLKRDPYELNNLAEN-PeyrSLLEKYARQLDNWLASQG 458
WP_102996280 388 ---------------vdyfikrgakayknE-P----FEELYDLQNDPFEQHNLASH-PdykSIKKKLTNDMFNWMKDQG 445
WP_013630607 402 wgnrtyhetirvkdrfpeayrvlaemdpqNlGgtvhRVELYDLQNDPDEMQNLAAN-PkfrAQGERLLGVLRDWgEETE 479
WP_038555186 379 qywp----swvfdasddpeildlvtryqnR-P----AEELYNLTADPNEMQNLIGR-DdlgEIKQNLSQKLDEWMKAQG 447
WP_110172312 383 agyfa---swrdkaatdpaaaavvaryhqR-P----AEELYDLRADPEELQNLASD-PrhaGQLRTLRAELDAWMTANG 452
WP_077023658 371 wk--------klantgnedaaakvkryqfR-P----EVELYDVVNDPLELHNIADD-GqfaDVKAELRSKLEQWMQQCG 435
WP_095414025 380 tphnkywptwmahswnnptiyglvkrymvR-P----AEELYRLSEDPYEMTNLADR-AefaEIKARLAKELDRWLAEQK 452
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