Conserved Protein Domain Family
COG4867

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COG4867: COG4867 
Uncharacterized conserved protein, contains von Willebrand factor type A (vWFA) domain [Function unknown]
Statistics
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PSSM-Id: 443895
Aligned: 84 rows
Threshold Bit Score: 372.588
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012873920   5 SYAHRYSRWdgtqridpfdadqimdaisddvladgdltralqrlfrwgtdqrdgqgmrgmrdllerirqmrqremnrydl 84 
NP_296112      2 ARITRYSKFegeldqlesselm---------------------------------------------------------- 23 
WP_012682075   1 MRFHTYTKFnpqladavdlqall--------------------------------------------------------- 23 
WP_011683971   1 MKWIKYSKYtgedmgigaedll---------------------------------------------------------- 22 
YP_143903      1 MKAIRYSRYeggleelspeeil---------------------------------------------------------- 22 
WP_013157578   1 MR-VRYSKYepgfddltaselm---------------------------------------------------------- 21 
WP_013178622   1 MPTTRYSKYeatlddldmadlm---------------------------------------------------------- 22 
WP_013704710   1 MK-VRYSKYeggleqldltevm---------------------------------------------------------- 21 
WP_014099609   1 -miTRYGKWdgldldqfnleqll--------------------------------------------------------- 22 
WP_025411525   1 MRFHTYTKYspeladavdlqsll--------------------------------------------------------- 23 
WP_012873920  85 gsvledinrrlddvieteragierrleqgrqrlerqsqagaqpsqqgqsgdsgatgeqgqagesgesgeagedgegyden 164
NP_296112        --------------------------------------------------------------------------------    
WP_012682075     --------------------------------------------------------------------------------    
WP_011683971     --------------------------------------------------------------------------------    
YP_143903        --------------------------------------------------------------------------------    
WP_013157578     --------------------------------------------------------------------------------    
WP_013178622     --------------------------------------------------------------------------------    
WP_013704710     --------------------------------------------------------------------------------    
WP_014099609     --------------------------------------------------------------------------------    
WP_025411525     --------------------------------------------------------------------------------    
WP_012873920 165 lhrllermaarnrevldslppdpagrikalqdyefmdptarqkfqellamlqqqmlqqtfqgmqqaiqemtpediadmrq 244
NP_296112        --------------------------------------------------------------------------------    
WP_012682075     --------------------------------------------------------------------------------    
WP_011683971     --------------------------------------------------------------------------------    
YP_143903        --------------------------------------------------------------------------------    
WP_013157578     --------------------------------------------------------------------------------    
WP_013178622     --------------------------------------------------------------------------------    
WP_013704710     --------------------------------------------------------------------------------    
WP_014099609     --------------------------------------------------------------------------------    
WP_025411525     --------------------------------------------------------------------------------    
WP_012873920 245 mlrelnemleerarggepdferfmhkyghyfgpninsldelldhlarqmaamqslldsmtpemraqlqealdavlsdpgi 324
NP_296112        --------------------------------------------------------------------------------    
WP_012682075     --------------------------------------------------------------------------------    
WP_011683971     --------------------------------------------------------------------------------    
YP_143903        --------------------------------------------------------------------------------    
WP_013157578     --------------------------------------------------------------------------------    
WP_013178622     --------------------------------------------------------------------------------    
WP_013704710     --------------------------------------------------------------------------------    
WP_014099609     --------------------------------------------------------------------------------    
WP_025411525     --------------------------------------------------------------------------------    
WP_012873920 325 qqelaqlgenlaqlmpnnpyhrefslsgdE-----ELTlgeamrlMERLREMEEVEDQLRSVRDWRDLEHVD-HDKIREL 398
NP_296112     24 ----------------qmiqeallgqgmnD-----PWDp-----dPNARPSMDDLFDAILEALAERNMIPEEqLLEALQA 77 
WP_012682075  24 ----------------dqladfllqsgfaGgs--eGYWgd---pgDEPDRSVGGLQEAILQALIESGQLTPDiLKALRGE 82 
WP_011683971  23 ----------------qalsdfllqsgfnTqy--mPMS-------EWNQHTLEDLKNAIQQALEQGKLFDEEaLQEMMER 77 
YP_143903     23 ----------------slledflldsgfsD-----PFQryd--pdPDRAPTLEDLYDALLQALLKNELVPEDwLREARFA 79 
WP_013157578  22 ----------------dmledflldsgfsD-----PYNryd--pdPDRQPSMEDLYDALLQALLEQDRIPEEwLREARFA 78 
WP_013178622  23 ----------------kmiqdrllesgfrRn----PWDp-----dPNYQQTLQDLYDAIAEALINHELVSEEmIEAAMNA 77 
WP_013704710  22 ----------------dwlkdflldsgfnD-----PFNryh--pdPERQATLEDLYDALLRALAERDLIPEAwLEEAAEA 78 
WP_014099609  23 ----------------eklsdfflqsgfsQg----GWSrr----iQDPDQSLEALREAIRQLIRSGELLDETdLKALQDA 78 
WP_025411525  24 ----------------dkladflldsgfaGgphyhPYWge---tgDEADRSLDALRQAILEALMESGQFTPEmLEALRGD 84 
WP_012873920 399 LGDDLa---qDLDQLRQLTKLLEDAGYIQRTR------------------------RGYELTPRGVRKIGQKALQDIFQH 451
NP_296112     78 -DDVRet--aLGQQIERLMDKLQQDGFIRKEFgdedgqg----------gagnpgeATFQLTDKSIDFLGYKSLRDLMGG 144
WP_012682075  83 GDEVSee--kLAQLLDGLVQRLVEDGFLSMEStgqvptghqpvtgkgslsqaaardVQFNLTGKGIDFLGFKTLRHLLGS 160
WP_011683971  78 LQKMTpe--qMDKLLENLIQKMVDEGQITIEDpanqpaag--------sgpgkdtkVKFEVTDKSLDFLGFKTLKDLLGS 147
YP_143903     80 -DRKEet--rLYQAIQGMIRKLQEAGYLRLPGedptdpaqg-------gyrgeageARFELTEKASDFLGLKSLRELLGA 149
WP_013157578  79 -DRKEdt--rLYREIQKLIQRLREEGFIQPQGqetlepstg------mgqqgqaqdVRIELTQKSVDFLGLRSLRSLMGA 149
WP_013178622  78 -ENWMds--kFGEVVRELAQRLEREGYLKPTGgdeqsdptqpgl-ggqgpdrdpgqVTFELTNKAIDFLGYRTLRDVLGG 153
WP_013704710  79 -TRREds--rLHRELERLVQRLEDEGFLRRPDadpsrpapg------egfrgeagaARFELTQKSIDFLGLRSLRELMGG 149
WP_014099609  79 SGALDen--kLDELVDALIQRLLEQGYLRATPdergtptprpg--qgriekdegarIKFALTEKGMDFLGYKALSQLLGS 154
WP_025411525  85 AQEGSdaeasLAQLLDQIVQRLTAEGYLNVQAppqmpstqqpvtgrgslshkaskdVQFQLTDKGIDFLGYKTLRHILGA 164
WP_012873920 452 LKKDRFGQHQLDRSGRGGERTDDTKPYEFGDPFLLHLPKTVMNAVYRDG-AGs--PVRLQPDDFEVFRTELVTQSSTVLM 528
NP_296112    145 LGRSSAGAHDTREYASGVEMTGELKNYEFGDTLNLDTTATLGNVISK-G-FD-----QLEEADLVIRQAEYSSSAATVVM 217
WP_012682075 161 LGKSSIGNHDTPQLATGVESDAWSKPYEFGDSLNLDVPATLANALARTGsLDv--PIDLDYGDLMVRQSEYRSSCATVLM 238
WP_011683971 148 LGKSSFGRHDTRDLATGIESNGSTKHYEFGDTLNLDVSETLFSAIRREG-AKv--PLNLDYADLHVHQCEYQSSCATVLM 224
YP_143903    150 LGRNPPGLHPTPHHAPGVEKTGETKPWEWGDPLELNVPETLKKAMAK-G-LE-----RLSHEDLVIDLAEYTASMSTVVL 222
WP_013157578 150 LGKNNPGAHATRHYASGVESSGETKPYEFGDQPNFNVGETLKRVAVK-G-VE-----NLEEGDLVVELAEYTAAMNTVVL 222
WP_013178622 154 AGKSSVGAHETKFQTTGVETTAESKPYEFGDTLNLDVATTFQNAAKH-G-LRedgTFELEYGDLQVLQAEYYSSAATVVL 231
WP_013704710 150 LGRNAPGMHATRHYATGVEASGETKAYEWGDQLNLHLPETLKRVLPK-G-LE-----RLSEEDLVVEMSEYTAAMSTVVL 222
WP_014099609 155 LGRSYAGRHDTQHLSTGIEAFQSSKPYEFGDTLNLDVNATLLSAIQRHG-LGv--PLEVEYSDLMIHQSEYTSSCATVLM 231
WP_025411525 165 VGKSSVGSHDTPYLATGIEADGVSKAYEFGDVLNLDVNATLMNSLARTGkIEv--PMDLDYPDLMVRQAEYRSSCATVLM 242
WP_012873920 529 VDMSRSMLYNG--CFTAAKKVALALDSLIRSQFPRDNLYIVGFSYVATELKPSMLPGISwdEYNYGTNMQHGFMLARQLL 606
NP_296112    218 LDCSHSMILYGedRFTPAKQVALALAHLIRTQYPGDTVKFVLFHDSAEEVPVSKLAQAQ--IGPYHTNTAGGLRLAQQLL 295
WP_012682075 239 LDTSHSMILYGedRFTPAKKVALALTHLIRTQFPGDTIRVVLFHDSAEEIPIETLAMAQ--VGPYHTNTAEGLKLARRLL 316
WP_011683971 225 LDCSHSMILYGedRFTPAKKVAMALAHLIRTQYPGDSLRCVLFHDSAEELDISQLARVQ--VGPYYTNTRDGLILAQRLL 302
YP_143903    223 LDCSHSMILYGedRFTPAKKVALALAHLIRTQYPGDRVRFVLFHDTAEEIPLAKLPLVQ--VGPYHTNTKAGLELARTLL 300
WP_013157578 223 LDCSHSMILYGedRFTPAKRVALGLSHLIRTQYPGDQVRFGVFHDSAEEVPLGRLPTVQ--VGPYHTNTAEGIKLARKML 300
WP_013178622 232 LDCSHSMILYGedRFTPAKQVALALAHLIQTQYRGDTIQFALFHNSAEEIPLARLAQAQ--VGPYHTNTAEGLRLAQKLL 309
WP_013704710 223 LDCSHSMILYGedRFTPAKRVALALAHLIRTQYPGDQVRFVVFHDTAEEVPLAKLPMVQ--VGPYHTNTAEGLRLARKIL 300
WP_014099609 232 LDCSHSMILYGedRFTPAKRVALALTHLIRTQYPGDTLKLVLFHDSAEEVPLGRLSQLT--VGPYHTNTAEGLRLARRLL 309
WP_025411525 243 LDTSHSMILYGedRFTPAKKVALALTHLIRTQFPGDSIRVVLFHDSAEEIPLARLAHAQ--VGPYHTNTAEGLKLARRIL 320
WP_012873920 607 GRHKGGNKQIIVITDGEPTAHF--DGTQVRFSYPPTYQTLQETLKEVARCTREQIVINTFMLERSPYMAGFVSEMAKINR 684
NP_296112    296 KRENKDMKQIVMITDGKPSALTlpDGRIYKNPYGLDPYVLGTTLREVANCRRSGIQINTFMLARDPELVGFVQRVSEMTK 375
WP_012682075 317 LAQKKDMRQIIMITDGKPSALTmpDGQVYKNSMGLDGHVIGETLREVAACRKSGIMINTFMLARDRALVEFVKRVSEISR 396
WP_011683971 303 NQERKDMRQIVMITDGKPSCLTleDGRIYKNAFGLDPLVISKTLEEVNRCRKQGILINTFMLASDFGLVNFVQKVTEICK 382
YP_143903    301 RKMGGEMKQIILITDGKPSALTlpSGEIYKNAWGLDPLILAETLKEATLARREGIPIHTFMLAREPELLAFVKKLSQITR 380
WP_013157578 301 KKMGGEMKQIIMITDGKPSALTlpSGQIYKNAWGLDPVILAETLKEATLARKEGIPIHTFMLAREPELLAFVKKITQITK 380
WP_013178622 310 KRQNKDMKQIVMITDGKPSAITlpNGRVYKNAYGLDPMVLGETLREVGNCRRAGIQINTFMLARDPELIAFVQRVSAMTR 389
WP_013704710 301 RRMGGEMRQVIMITDGKPSALTlpSGQIYKNAWGLDPMILAETLKEVSAARREGIPIHTFMLAREPELVAFVRKITRITR 380
WP_014099609 310 LAQRVDMRQIIMITDGKPSALTmeDGRIYKNSMGLDPMIMEATYREVAQCRRSNIAINTFMLADDPYLVNFIKRLTSIAQ 389
WP_025411525 321 LAQKKDMRQIVMITDGKPSALTmpNGMVYKNSMGLDAQVIAQTLREVADCRRAGIVINTFMLARDRALVEFVKRVSEISR 400
WP_012873920 685 GRAFFATPDHLGEYILVDYVANKRTRVR 712
NP_296112    376 GKAYFTTPQNIGQYVLQDFMTNKTKVMN 403
WP_012682075 397 GKAYFTNTMSLGQFVLMDFLKKKTSRVR 424
WP_011683971 383 GKAYFTTPYTLGQYLLMDYMNRKTRTIH 410
YP_143903    381 GKAYLTSPRNIGKYLLLDFLNKKVRRN- 407
WP_013157578 381 GKAYLTTPGNIGKYVLLDFLTRKVSKN- 407
WP_013178622 390 GKAYFTTPHTIGRYVLMDFQSRRTKTVN 417
WP_013704710 381 GKAYFTTPRNIGRYVLMDFLNKKVRRVN 408
WP_014099609 390 GKAYFTTVMTLGEYVMMDFLRRKQKKVR 417
WP_025411525 401 GKAYFTNTMTLGQFILMDFLRRKTRKVS 428
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