2HDI,5MZS,1FEP,6V81,6I96,6E4V,1XKH,1XKW,6FOK,2YSU,6Z9A


Conserved Protein Domain Family
TonB_dep_Rec

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pfam00593: TonB_dep_Rec 
Click on image for an interactive view with Cn3D
TonB dependent receptor
This model now only covers the conserved part of the barrel structure.
Statistics
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PSSM-Id: 395474
Aligned: 657 rows
Threshold Bit Score: 38.5978
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2HDI_A  147 DTTiq------eHRDRGDTYNGQFftSGPLIDGVLGMKAYGSlakrekddpqnstttdtgetpriEGFSSRDg--NVEFA 218  Escherichia coli
Q9AAN4  462 VLTp---------------------eGLRYISRTDITRQWYV-----------------------TYGYEYA-------- 489  Caulobacter vibrioides
Q8P331  434 AYGan-----rfISYDGDGFPIPLltPAMQAQASDVGSLFAR-----------------------RTGQISK---QYSGQ 482  Xanthomonas campest...
Q8P621  462 NWQlm-----stWAQGNKIEATMD--AFRADGTFEFDEGVVR-----------------------GFQFGIR---YGERE 508  Xanthomonas campest...
Q9A9L0  513 VFRae------gHYRFDDKFLGFItkIDAGVRQSDRSVSVEQfhl------------------fsGFYGGVPg--AVQAN 566  Caulobacter vibrioides
Q9A7G9  416 PATpn-----igRVFDKIGFQVADngFSQYDEGFNYADAGKV-----------------------TLGDRAPwggWGHDG 467  Caulobacter vibrioides
Q8P3F1  446 SILvtspfttvdYRNEGGDRPSISspLDLNDPNLGWGWAGGR-----------------------VNIQNEK---RVTQT 499  Xanthomonas campest...
Q9A9I1  450 PVQ-----------SITINDAAPRgnGNGALDAGDLGSQVAR-----------------------TWTNRQQ-------- 487  Caulobacter vibrioides
Q8P3V6  448 DFSk---------------------dFPVLQQQLGFGLNGLDps--------------------rTLVTGSAf--RNSYM 484  Xanthomonas campest...
Q8P6Y7  462 TWY---------PTAADSLAGTNGvvNPDFTAGNLGSQVLRI-----------------------YYQSQVN---EIKEG 506  Xanthomonas campest...
2HDI_A  219 -------WTPNQNHDFTA-GyGFDr--------QDRDSDs---lDKNrlerqnySVSHNgr--wdYGTSELK-YYGEkve 276  Escherichia coli
Q9AAN4  490 ---------EESKTDLKA-NlAWDi--------EHP--Iv---kSIKg------GVKYEta--drESNDVGT-GDENrfy 537  Caulobacter vibrioides
Q8P331  483 -------DKGGG----KL-DvSYDf--------DDGVLS-----RIAf------GVKYVds--srSFTDRDW-TNAKy-- 526  Xanthomonas campest...
Q8P621  509 ------------VKLD---TyRYLsp------vSTTCAD-----PNR-------SLYYFkd--plISDTCSGvSEAR--- 550  Xanthomonas campest...
Q9A9L0  567 -------GSAIP----AG-GcEAQw--------KAI--------DVVm-----------------SQNQCQA-GEFVpdp 600  Caulobacter vibrioides
Q9A7G9  468 a-----iRFPQVKEDVTTiDvHLE---------HELDGFit-qvSAG-------VNHTKrdkgktVSDNDLFlKNGR--- 522  Caulobacter vibrioides
Q8P3F1  500 rgaradlQFGEDKRNIKI-GtSYDqaertirgfDNSTAW---------------EQVIC------RGGGGNV-CNGG--- 553  Xanthomonas campest...
Q9A9I1  488 ----------HDIKEVRA-DvTYDl--------DDN--------GSRfd----fGLNYR------TSKMVQS-GSSTqqd 529  Caulobacter vibrioides
Q8P3V6  485 -------KSEIDQAQVNG-DfTFEn--------YSQLKF-----GIGs------TEVKNrs--afSNVQRDT-WGGNgta 534  Xanthomonas campest...
Q8P6Y7  507 r-----vDGTFDFDDGRF-QfGVS---------SANTKMnrltsDTNst--------------lgDWSVANAgNEPG--- 554  Xanthomonas campest...
2HDI_A  277 nknpgnSSPITSES-----------NTVDGKYtlpltAINQfl----tVG---------GEMRhdk----msdAVNLTGG 328  Escherichia coli
Q9AAN4  538 fykkdaSGNWTANSallgngshrwaNQGEFLFd---lPGKTlts--fmMGglqv-pmrlVDPDylkn---qayKYAATIP 608  Caulobacter vibrioides
Q8P331  527 ------TDGTLLRDtglvaqrydavYPGQYALptlrlSNDAl------NAliar-tltpESFD----------SCGRLAV 583  Xanthomonas campest...
Q8P621  551 ------LLPFNSIPgyw-----ayfNDFDPLK-----VTG--------LGsqglpainpqvMKd---------PVGYINS 597  Xanthomonas campest...
Q9A9L0  601 itgkpvFQGYTVNRptklt--tynnTIWVDDLggvtsGIPGf------WAid------pRDFDdae-----afHKKVFGG 661  Caulobacter vibrioides
Q9A7G9  523 ------QQVYVDAAdlvdp-tqlgfAGFGGVL-----SVN--------IG---------DAWRk---------YYNWAPI 564  Caulobacter vibrioides
Q8P3F1  554 ------PGSAIPNTalssylrpgpgGFITADF-----NRF--------LG---------DTNYyal-----rdSAPETNS 600  Xanthomonas campest...
Q9A9I1  530 l--gswGISNPRDVqqf-----apgLVKAFCMa---cQFNEfdlkqsgAGlvsf-radaIDLYnam-----skAYVARGN 593  Caulobacter vibrioides
Q8P3V6  535 adypddLWIPSSFAqyf-----daiDGSGNPPq---fNQLFl-----------------FDFErarqaaaqvaGDDALYR 589  Xanthomonas campest...
Q8P6Y7  555 ------MVALLQPVsitgm-fkdfnANGAAPSa---wRGDAdql-alwGG---------SQYG----------ATTRYNP 604  Xanthomonas campest...
2HDI_A  329 TSSKt---------SASQYa-------lFVEDEWRI---FE---PL-----ALTTGVRM-DDHETYge------------ 368  Escherichia coli
Q9AAN4  609 WTNEvlkrnllsgeETRASa--------YVQSTLTF---GD---TL-----TVVPGVRY-EDNNFKgsywrpesvkga-- 666  Caulobacter vibrioides
Q8P331  584 NNLNcntm---ratEAVSAa--------YVMATLRT----G---NW-----EILPGLRF-EHTSIDntfwaqpaavg--- 636  Xanthomonas campest...
Q8P621  598 LYPGnva----yqqAADSYkvtekstaaYFLANLEGg--TGsavPW-----TANIGARI-VQTKLAidqyls-------- 657  Xanthomonas campest...
Q9A9L0  662 AIRVtvpgqtydvtMKEQSa--------YGAANFEI----G---NL-----HGDFGLRV-IQTELNvkqnltgdtrny-- 718  Caulobacter vibrioides
Q9A7G9  565 LDANyyd----ktwEITEKvt-----tfFARANFQA----G---DL-----RGNLGVQVvKQEQASsgvving------- 616  Caulobacter vibrioides
Q8P3F1  601 ANTGasa----ggiREKNLg-------fYIETNAET----E---VWnr-tlRLNAGVRYvTTDQTItgpvtin------- 654  Xanthomonas campest...
Q9A9I1  594 PVNItgqa--nnrvDEDILa-------gYAQVTWKSelgGM---PA-----TLVTGVRY-EQTEVTsts----------- 644  Caulobacter vibrioides
Q8P3V6  590 ISPVfttd--rrvtEKSKNa--------YLQWNNSWddlRV---PI-----SLAAGVRY-EETKVDaqalvpvavgidwv 650  Xanthomonas campest...
Q8P6Y7  605 QYSAdnq----veeKTRAA---------YVQLELQG--------DIagmttNTRLGLRY-ERTDVEsvsqvatptgll-- 660  Xanthomonas campest...
2HDI_A  369 ---------------hW---------------SPRAY----LVYN------------------------AT----D---- 382  Escherichia coli
Q9AAN4  667 ----dgkttsarvqasSdrgm--------givLPSVI----ATWR------------------------PT----D---- 698  Caulobacter vibrioides
Q8P331  637 ------gveqvgafanNqtry--------nvvLPSVF----VNYRp-----------------------DG----D---- 667  Xanthomonas campest...
Q8P621  658 ----------sgnvfiGnvew--------ngvSPAIG----TN-Rln---------------------rQYtdvlPtanl 693  Xanthomonas campest...
Q9A9L0  719 -----gdtnadagdsvSkrky--------tdwLPSLN----AVYD------------------------VN----D---- 749  Caulobacter vibrioides
Q9A7G9  617 ----------tepgkpItptkinv-kddytdvLPSMN----LIY-------------------------------D---- 646  Caulobacter vibrioides
Q8P3F1  655 ---------girqvqvLdsdy--------ketLPSFN----VAWD------------------------VA----D---- 681  Xanthomonas campest...
Q9A9I1  645 -----------------------------lvrTPSA-----IIWTadndfslqtsatyqplagkgkynnLL----Paldf 686  Caulobacter vibrioides
Q8P3V6  651 annelpirvsnsafasGsgky--------eywLPSLD----LSFK------------------------LT----D---- 686  Xanthomonas campest...
Q8P6Y7  661 -----wqsnndfqlvrSaelqpfsektsynyiLPNLDfsidIT--------------------------------D---- 699  Xanthomonas campest...
2HDI_A  383 --TV---TV--KG-GWATAFK---APSLLQLSPDWts------------nSCR------GACKIVgS---PDLKPETSES 430  Escherichia coli
Q9AAN4  699 --EI---VV--RG-AVRRAYT---RPAFDQMIGATsis---------kdaDGK------IIAISIaN---PDLQPVTGIN 749  Caulobacter vibrioides
Q8P331  668 --GA---VY--RGsVWTSYTR----PAFVQLGGGRstd----------isADG------QTTITEgN---PDLKPIKSLN 717  Xanthomonas campest...
Q8P621  694 slDItdaQKlrFA--YNKAVArqdLPDLGRGLVSFyavng-----tpprnPALppdavlFLNGRSgN---PDLDPYRATN 763  Xanthomonas campest...
Q9A9L0  750 --NW---KF--RF-AYAKTMQ----PLDLGNYGGGlsiftadcgaalpnvRCV------TGAAASgN---PNLDPWRASN 808  Caulobacter vibrioides
Q9A7G9  647 --LGgghRL--RF-ALSKTMA---RPRMDDMRANVtpgfns---lvcsgqPCApgttvnPWSASGgN---PNLKPWMAKA 712  Caulobacter vibrioides
Q8P3F1  682 --NV---VM--RL-SSSRTLT---RPDPSAMLPNTnf------------sDPS------AQTATQgN---PNLAPYLSTN 729  Xanthomonas campest...
Q9A9I1  687 slDLrddLVgrF--SFSRTIA---RPDYGNLFAAQsagtp-----nrpvaNGA------IPLGSSgN---PDLEPLISDN 747  Caulobacter vibrioides
Q8P3V6  687 --DL---VL--RA-SYGETIG---RPGWGDIQGGQtls---------eiaRVE------GGTGQEgN---PGLKPLLSHN 737  Xanthomonas campest...
Q8P6Y7  700 -------QLkgRA-SFGQTIA---RAPYNNLIAGPtp------------nTPNgsilinPSNRAGgDsqnPQLDPLESDN 756  Xanthomonas campest...
2HDI_A  431 WELGLY-YMG--EEgwlegveSSV-TVFRNDVKDRISISRTSDVNAapgyqnfvgfe----------------------- 483  Escherichia coli
Q9AAN4  750 YDFSVEkYGE--DGq-----yLMA-SIYYKDLKNVMFVSGSTNTGSdfnvwtgd-------------------------- 795  Caulobacter vibrioides
Q8P331  718 VDLSGE-WQN--DAg-----gHAMlAGYYKRLTDYIYESGSDAANAgesg------------------------------ 759  Xanthomonas campest...
Q8P621  764 YNASWE-WYF--SDas----lVSV-GAFLIDVKSFPTTVTNIEPQPdadgv----------------------------- 806  Xanthomonas campest...
Q9A9L0  809 FDGAIEyYFG--RAs-----mLNI-SAFQLKIDSFVTGGTTTGRFPdqdgv----------------------------- 851  Caulobacter vibrioides
Q9A7G9  713 ADLAYE-WYVspATy------VSV-AGFYKKLDTYIYSQTGKFDFTgiprpttata------------------------ 760  Caulobacter vibrioides
Q8P3F1  730 VDFGGE-WYTg-GEg-----yVGL-TLFNKRISGFTVNGVRRIPFNdlgvpyesllpiqq-------------------- 781  Xanthomonas campest...
Q9A9I1  748 FDVSLEwYYK--PSs-----yITA-GFFEKRVNNFVGTGTVSQNLFglrdvssgaagtrsgnakailtaigadqtdvnlf 819  Caulobacter vibrioides
Q8P3V6  738 IDFSLEwYYS--DAs-----yASV-GFFRKNIDNYIGVTTRNDTSLglntpiggaywneal------------------- 790  Xanthomonas campest...
Q8P6Y7  757 LDLALE-WYFadASy------VSA-TFWNKRVSNFIGNTVSRESLYgltdptsg-------------------------- 802  Xanthomonas campest...
2HDI_A  484 -------------------------------------------tgangrripvFSYYNV--NKA-RIQGVETe------- 510  Escherichia coli
Q9AAN4  796 ----------------------------------------------vikdaggAEISRLdnAKNgSVLGIELg------- 822  Caulobacter vibrioides
Q8P331  760 --------------------------------------------------tasTRFVRPqnGGDgRVLGMEAa------- 782  Xanthomonas campest...
Q8P621  807 -------------------------------------------------vrlgGPVESIvnGGGgKIKGFEI-------- 829  Xanthomonas campest...
Q9A9L0  852 -------------------------------------------------irrtVNVSLPvqGDGgSVKGLEVg------- 875  Caulobacter vibrioides
Q9A7G9  761 -------------------------------------------ippgitispiGQITLPanGNGgVVKGLEFs------- 790  Caulobacter vibrioides
Q8P3F1  782 ---------------------------------------agldqrggpnaatvDVQTQVnaDGVlNIRGTEAi------- 815  Xanthomonas campest...
Q9A9I1  820 tmtallqttgsaaaaqaqfqanrgvtgdlnqafvdqilaavdlspnstdplfnFQVSKPinNRTgKIHGFEIa------- 892  Caulobacter vibrioides
Q8P3V6  791 ---------------------------------------gngcasadltcirnYIFRNRggAPG-VVRGADAtgvisgqp 830  Xanthomonas campest...
Q8P6Y7  803 ---------------------------------------------pdaqaalaFLQSGAcaAQV-GASGNDVaaacsand 836  Xanthomonas campest...
2HDI_A  511 ------------------------------lKIP-----Fnd---------------------eWKl------------- 521  Escherichia coli
Q9AAN4  823 ------------------------------lRQRft--tLpg---------------------fWNgf----------gv 839  Caulobacter vibrioides
Q8P331  783 ------------------------------vRQT------------------------------FQglpapl---dgfgi 799  Xanthomonas campest...
Q8P621  830 -------------------------------GYQqafdfLp----------------------gWLsgf---------gt 847  Xanthomonas campest...
Q9A9L0  876 ------------------------------aKVA------------------------------FSdvlpdm---gvisn 892  Caulobacter vibrioides
Q9A7G9  791 ------------------------------gAVD------------------------------LGqf----------ad 800  Caulobacter vibrioides
Q8P3F1  816 ----------------------------------------------------------------WVqpl---------dk 822  Xanthomonas campest...
Q9A9I1  893 ------------------------------aQHF------------------------------FGdtg--------fgv 904  Caulobacter vibrioides
Q8P3V6  831 gd-------------------pvanfaitapANQrs--aSld---------------------gWEfnlqhm---fgdsg 865  Xanthomonas campest...
Q8P6Y7  837 tslfaamallrnaaatgglgayngssaqslaLENayditGnssdplyqfdvsrpinqnkanihgWElggqyffgssgfgi 916  Xanthomonas campest...
2HDI_A  522 SI--N-YT-------Yn----dGRD---VSN---------GENKPLSD----L--PFHTAN--GT--LD------Wkp-- 557  Escherichia coli
Q9AAN4  840 SG--N-VT-------F------QKT---EADirvg-nlgkNLSRRLIN----A--PDSIVNasLF----------Ynkh- 882  Caulobacter vibrioides
Q8P331  800 GG--N-VT-------R------QTT---RVDlge----egFAHERIQN----A--PDLLANaeVF----------Y---- 836  Xanthomonas campest...
Q8P621  848 NI--N-YT-------F------SDA----DTdn-----tdIEGNTLPIgd----nSKHQANavLW----------Yqk-- 886  Xanthomonas campest...
Q9A9L0  893 FGvdSnYT-------Ysp---sHES---RLD---------LEGNEIPF----FdnSKHQFN--L---VG------W---- 931  Caulobacter vibrioides
Q9A7G9  801 LL--KgFG--------------MQGslsLTKsnlnpttstDPKQKVRI-------PGLSGT--VYnvTG------Y---- 845  Caulobacter vibrioides
Q8P3F1  823 LV--DgLG-------F------SVN----YThvt----qsSEGEGVPAvavgV--APNLWN---G--TV------Y---- 862  Xanthomonas campest...
Q9A9I1  905 SG--A-YTmvrgdvaFnngaspSQD---QFA--------------LLG-------LSDTAN--AT--LI------Ydkng 947  Caulobacter vibrioides
Q8P3V6  866 FG--VsAN-------Y------TMV---DSGltyd-nyviGEQFALEG-------LSDSAN--V---VGfydrdkWqv-- 912  Xanthomonas campest...
Q8P6Y7  917 YA--N-YTivegdvgF------DNTvidRDQfall-glsdTANAMLMY-------EKYGFSarLA--------------- 964  Xanthomonas campest...
2HDI_A  558 ---lALED-----WSmy------mSG--HYt---GQkRADSAT--AK---------TPGGYTIw--NTG--A--AWqvT- 600  Escherichia coli
Q9AAN4  883 -gvrAELA-----YSr-------vGM--IYkd-vRT----DND--DT---------WVQPMRRl--NFN--A--NYqlP- 924  Caulobacter vibrioides
Q8P331  837 ----EKGP-----WSvnlsyhysgEYvsVYdy-lNQgARWDNL-------------WIKPITRv--DLH--V--GY--Ap 885  Xanthomonas campest...
Q8P621  887 ---dKLQArvaynWR---------SK--RFsq-vNSgAWGDELa-----------iWNDDVGYl--DAS--F--SYdvN- 933  Xanthomonas campest...
Q9A9L0  932 -------------YQddk---lqaRV--AYny-rTDrLSGTMG--GGgnavipimqKATGYv----DVN--V--SYnvRd 982  Caulobacter vibrioides
Q9A7G9  846 -------------YErgg---fqaRIsqRYr------SAFKGEvvQLf--------ATRGFTEilaDKQvdAqiGYt--- 892  Caulobacter vibrioides
Q8P3F1  863 -------------WEkna---asvRL--SYtw-nDDmVISGANqnGIpya----rlNADARGQl--DLS--A--SY--A- 910  Xanthomonas campest...
Q9A9I1  948 isarIAYN-----WRdkf----laAT--NR----GG--SRNPV--YT---------A--PFGQl--DIN--V--SYdvT- 990  Caulobacter vibrioides
Q8P3V6  913 ---rAAYN-----WRde-----flAA--RFdg-sGQpNPV----------------YTEAYGQl--DLS--I--GYqwT- 953  Xanthomonas campest...
Q8P6Y7  965 -------------WNw--------RD--EYliaaNQ----DNSnrNPy--------YVEAYQQw--DLS--VsyAF--S- 1002 Xanthomonas campest...
2HDI_A  601 -KDV-----KL-RA-GVLNLGDkdl----------------srdDYSYNed--gRRYFMAVDYR 638  Escherichia coli
Q9AAN4  925 -HGW-----QI-GM-AVENILNdqsywatqgk---aetllshdrKGGYVet--gRTYMINTSWT 975  Caulobacter vibrioides
Q8P331  886 tDHL-----RV-DL-SVANLTrqhsywah--------vghdntaISDIVds--gMTSLVTAKYV 932  Xanthomonas campestris pv. campestris
Q8P621  934 -DHL-----TL-YA-QATNLTGeserr------------yaqwtNHYYDqnifeRRYYAGLRLR 977  Xanthomonas campestris pv. campestris
Q9A9L0  983 nVTVyfngsNV-TG-EIEDYYlrfak-------------gktqyANQNEfe---pRYTLGIRAR 1028 Caulobacter vibrioides
Q9A7G9  893 --fQdgpmeNLgLLvQVNNLTNtpyrtrlgldgggtktsgggalPETYEky--gRQILFGVNYR 952  Caulobacter vibrioides
Q8P3F1  911 -LDWlpskpQI-TL-NVTNLTDeplrtt----------yawpnaTYDLYqp--gRTVMLGIRGT 959  Xanthomonas campestris pv. campestris
Q9A9I1  991 -PKL-----AI-SL-EGINLTKeslrty----------ardenqLWFAQel--dRRILLGARYR 1034 Caulobacter vibrioides
Q8P3V6  954 -ENL-----SL-SL-EAINLTDevqrqhg---------rqsnqiVYATQtg---pRYMLGVRYK 997  Xanthomonas campestris pv. campestris
Q8P6Y7 1003 -KQL-----SI-GF-EAINLTGedvrwhg---------rsdkqiIRLIDqq---pRYTLGVRYA 1046 Xanthomonas campestris pv. campestris
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