Conserved Protein Domain Family
NirB

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COG1251: NirB 
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion]
Statistics
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PSSM-Id: 440863
Aligned: 768 rows
Threshold Bit Score: 191.123
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_084020733  22 PERIVVVGYGPVGARFVDEILPLvEAgLAELTVVGAEQEHAYNRVLLADFA-VGRTDRDTLDLTDGGRARAAGARILTGT 100
NP_228563      1 -MKVVIVGNGPGGVELAKQLSE-----EHEVTIVERETVPYYTKPMLSHYV-AGLAEEKSLFPYPIDWYEKKGIKLLLGT 73 
WP_015433711   2 SAPLVIVGTGMAGYGVLRALRHV-DT-RQPVWIAAADDGAAYAKFELATALaQRREAGQLVVATAEQMAYRFGATVEPHC 79 
WP_048164680   1 -MKILVIGNGPAGFTLAKEL----SK-DFDVTIIEKENSLYYNKPMLSHYI-AGFVGEMALFRYSHEWYDKYGIELNLGV 73 
WP_011237507   2 NAPLVIVGTGAAGYALLRALRQI-DR-DRPLVLITRDDGAAYEKFHLARALgARTRPRGLVLATVEQMAHRYGATILAHR 79 
WP_011249779   1 -MEIVIIGNGPGGVELAKEL----SG-EHEVLIFEREEVPFYSKPMLSHYI-AGLIEKEKLFIYPLDWYERKGINLKLGE 73 
WP_125931817  83 DEYVVIVGAGIAGWSVAEAIRRR-EP-TRPVLLVSACPGLVYPKPAISMALaMNKKPEDLVDTDAAGKAAELNIEVRTDT 160
WP_011369460  76 HADVLIIGAGYAGWQAAENIRAA-LP-EAEISLLTACDGTVYPKPSLSMALsQGRTPDDLKEMTAEAKAAELNMGVKTRT 153
WP_081441161 101 EDAVVIVGSGIAGWTAVEQLRAQ-DL-DRQITLITADDGCVYPKPSLSMAIgQGRSADDLIEQSGPDKAEALGVTLQANT 178
WP_014801999   1 MSNVVIIGSGMAGIGLA-ELLAQ-DS-KFSVTVVSGETSGYYSRPLLSHAFaSEEVFGRTVLSDVASLQQKFR--FIAGK 75 
WP_084020733 101 SVTSVNRSIRTVSLG-----DGSTVPYDRLVLATGARANVP-TLDGVkrvrrglmkpgpdaatldtldapLPRGVSALRD 174
NP_228563     74 TAKRIDAEKKVLETD-----RG-TLEYDVLVLATGAKPRTL-KIPGW-----------------------E--RMYTLRT 121
WP_015433711  80 RVVAIDRERRVVRTQtsgraS-GEQAYSRLVLATGAEAVRPsAMRGS-----------------------AADRILTVSS 135
WP_048164680  74 EAERIDETRKKLVTT-----NG-EFEYDALVLATGARAREP-EVEGK-----------------------E--HLMTLRT 121
WP_011237507  80 HILRIDRLRHELVMR-----E-GRHGYGQLVLATGAAALREpGLRGT-----------------------AASQALTLGS 130
WP_011249779  74 EAKLIDRVRKVLVTD-----KG-EYPYDILVIATGARAREP-TVDGK-----------------------E--HLLTLRS 121
WP_125931817 161 RIVKLDTRRRRLTTV-----R-GGIQYGKLVLALGAHQRVL-PLDGD-----------------------AADDVARVND 210
WP_011369460 154 KVMSINTKRKKVMTT-----S-GSFQYDKLILATGAKAMVP-QVEGN-----------------------AAHDIMTIND 203
WP_081441161 179 RVLSIKPKDKRLMTT-----K-GKVAYGDLVLALGSSQRRL-ACEGD-----------------------AADQILRVND 228
WP_014801999  76 TVTQILPEAKQVLFE-----GGKKIDYDLLVLATGSEAFVP-PPWLP-----------------------YQQNFLTLNR 126
WP_084020733 175 LADAATVLAAVR-AGQRIVVLGAGVLGMEIALAAAAAGAQVCVVYHGEIPMNRNLDRGGGSVLTRAARLAGVAMVNHARA 253
NP_228563    122 IEDAKRLKGAVE-REKDLLIIGGGFIGLEIAGNLSKQGIKVKVVEKMTRLM--GLDEELTERIKGELEKHGVEFYLGRDV 198
WP_015433711 136 LAEYTYLRSELA-GRKRVVVLGGDLPGCELAGNLLRGGCEVTLLEPQNRLLCDSFPTLCAGRIEQDLRSAGVSLWIEDGI 214
WP_048164680 122 FEDAKRIKESLE-SEDEPVIIGGGFIGLELASNLAKAGFKPRVVHRRATFL--GLDEELSGILKEKLENAGVSFLLNANL 198
WP_011237507 131 LADYAYLRSELA-GRNRVVVLGGGLAGCELADNLARSSCHVTLLEPANQLLAETLPALSAARVAQALQAAGVQVMTEDGI 209
WP_011249779 122 IEDAEGIKALLE-EHGEAVIIGGGFIGLELAGNLAKAGYGVKLIHRRDTFL--GLDEELSSLIREKLEESGVEFHLGAEL 198
WP_125931817 211 LGSYKQFRAKLTpEVKHITILGAGLIGCEFADDMTSAGFQVTVVDPADRPLQSLVPRAVSAELVSRLAHKGVDWRLGSTM 290
WP_011369460 204 LSAYRRFYKALV-GKQSVTLIGGGLIATELAEDLSSQDIEVNMVVRGAHLMSQILPEAISNSLETKLKENGVHLYKNSEL 282
WP_081441161 229 LTSYRKMREKLSrGPQHVTLIGAGLIGVEFAEDLQAGGHRVTLLDLGAQLLGRLVPTPVARLLLSSLRERGTEFMPGISI 308
WP_014801999 127 YDDAVAIRKLRDsGARRWAIVGGGLIGCEIASDLAKAGDEVVLVHAVARLMERIFSPEDSARLAEHLQQQKIKVMLNTMV 206
WP_084020733 254 ESVLfhhdehGAeRFEALICADGKQISGDLLLLSCGVGARTELAHLAGLPVSTGVLVD-ESLQSwADASIHAIGDCAHVA 332
NP_228563    199 ERIE------N-----DVLVTDKEEIPARVILCSIGIVPEVSLAKESGLDVNRGILVD-KTFRT-SKPDIYAIGDCAEHE 265
WP_015433711 215 HRIE------QRgYDLEITTLSGLRLIAEVVVAALGSRPRSTLAREAGLDVASAIVVN-GQMRS-SDEHIFAVGECAQMA 286
WP_048164680 199 MKAD-------E----KGILTDKGYIKSKTKICAIGIVPNKEIAEKSGIKTNRGVLID-ERFQT-SAGDVYAIGDCAEYE 265
WP_011237507 210 QRID------QGpDELELTTLAGVRFPADLLVLARGVVPRTELARDAGLAVARGIVVD-PALGT-VDPDIFALGECAEID 281
WP_011249779 199 LKAD-------E----NGLLTTRGYIEGKVKICAIGITPNVEIARRSGIHTGRGILID-DHFRT-SAKDVYAIGDCAEYS 265
WP_125931817 291 LSLA------KAtKGYKAVLDDGCSVQTDIVLSAAGLIPNTQLAAKADLAIDAGVAVD-NTMRT-SAEHVYAVGDCASLA 362
WP_011369460 283 KEIN------ESeNGYVLQTDQGEFLETNIVIAAIGLAPNLDLAKKAKLETNRGICIN-GACQT-SDPDIFAIGDCAEAG 354
WP_081441161 309 AALN------TNgNRLRATLSDGELLTTDLVISAVGLVPNTDLARKAGLNVNRGIVANaDNMCT-GDPHIYAIGDCVEVD 381
WP_014801999 207 TTFT------REnGRTLLSHADGD-IEVDAAIVAVGFRPRTALAAAAGLKVNRGIVTD-EKFQT-SVAGIYAIGDGAEVD 277
WP_084020733 333 grpadtdlgaawngarvapaGGPSG----LIGPGWRQADRLAARFT-AEItarAAapdpdaqGStapaaatvavepgASV 407
NP_228563    266 --------------------GIICG----TAKAAMAHAKVLANTLK-GIP---DEy-----dFH-------------FRS 299
WP_015433711 287 ------------------------NrvfaHVDDIEESVRVLAGGLTgGRN---RMlr----wHP-------------RS- 321
WP_048164680 266 --------------------GIICG----TAKTSMEHARTLANILR-GKE---ALy-----dFN-------------FRS 299
WP_011237507 282 ------------------------GrlfrLAEEIEAGAQVLAEVLC-GRK---RRmr----wPA-------------RL- 315
WP_011249779 266 --------------------GIICG----TAKAAAGHAKVLANLLR-GKE---DRy-----pFE-------------LRS 299
WP_125931817 363 ------------------------GqvfaYIEPIRRQAEAIAADIA-GAR---ERfm----pLP-------------PL- 396
WP_011369460 355 ------------------------GvlqaYLEPIRRQAKAIAAHLK-GEDt--DQfq----vLP-------------SL- 389
WP_081441161 382 ------------------------GrsyfYIEPIRRQAATVAAALV-GKH---RPfe----hLP-------------TA- 415
WP_014801999 278 ------------------------GnlfpFVAPIRAQVKHLAGLLL-GTVs--GGws----aPA-------------VK- 312
WP_084020733 408 VMLKAEGIDVVAAGDTTA----DPfdaaladaeahshgcasaDpappavarlAVaQWADpeHGrYVKMVT-RGGILTGFV 482
NP_228563    300 SYFKFGDFPIAIVGELTDr---GEw----------------------------I-------DS-ETKSFY-RDEKIVGVV 339
WP_015433711 322 RRMQTGCSEAVICEPPRGl--dGEw-----------------H----------E-CATG--RG-VRALFHdRSGKLRGFA 368
WP_048164680 300 IVFKFGDLPITIIGRVKNe---SRw---------------------------V--------DE-NIKVFL-ENNMVVGAV 339
WP_011237507 316 RRLQIESCPVTVCEPP-Pl--aGEw-----------------H----------E-AATQ--RG-VRAVFRdRRGALRGFA 361
WP_011249779 300 SVFKFGDLPIAIIGKTRGe---GEw---------------------------L--------DE-HTKAFF-QDGKLVGAV 339
WP_125931817 397 VKVKTPTMPISVCKPSGAva-dDDw-----------------V----------A-IEEN--GD-SLHFEIaGPDTIAGFA 444
WP_011369460 390 IKTKTPSLSIMISPPLHAt--hGQw-----------------E----------Q-TIMV--GD-NQRLLYkEGEGVSGFA 436
WP_081441161 416 IRVKTPSLPINVCPPDRSvadfGNwhvh-----------tpdE----------V-NEAD--KG-ACRMDFlVRNQLMGYA 470
WP_014801999 313 VRVKV-------------------------------------H----------------------------------GFA 321
WP_084020733 483 CVGMPRTGAELTLLF--ERGSELPadRsVLLrfdgpdydpasagDA 526
NP_228563    340 VLSDVRKAREWEERL--RSTR------------------------- 358
WP_015433711 369 LVGA--TTDETHRLL----SG-VG----HWWs------------G- 390
WP_048164680 340 VLEDLKEAMRLEKLI--KNGLSLK--Efg----------------- 364
WP_011237507 362 LLGD--QVAAAERLL----GE-LG----R----------------- 379
WP_011249779 340 VIGDIRKAFSIEKEL--KKELy-----gA----------------- 361
WP_125931817 445 LAGD--VASQAGGHY----RR-LG----GQTq------------AA 467
WP_011369460 437 LSGD--LVTSANALY----QE-LF----SA---------------- 455
WP_081441161 471 LTGR--CTPQSEYLHpiVIDS-LF----GATt------------AA 497
WP_014801999     ----------------------------------------------    
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