Conserved Protein Domain Family
MATE_yoeA_like

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cd13138: MATE_yoeA_like 
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA
The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Statistics
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PSSM-Id: 240543
Aligned: 129 rows
Threshold Bit Score: 292.441
Created: 23-May-2012
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O34474    18 VWRSMSLFLVPLLLSNVLQSVGQLVGMMAVGRWlg------vdAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAK 91  Bacillus subtilis s...
ADO83895  17 LWRAIFLLAVPVAINDFVRSMYNLIDTFFVSNIgs-------mEIAAITFVGPLNNIIRAISLGMSVAGTNLIAREIGRK 89  Ilyobacter polytrop...
EFP59930  11 LTKALLRMAVPLFILNLVNSLYNIIDTFWVGQIge-------lQVGAVSLVGPIMWCAQSVAMGLSAAAIALISTRLGAN 83  Erysipelotrichaceae...
ABX81111  18 IWLYMLLLSLPILINNLIKSFNGMVDIYFIARIkdvstetidsAIAALNIHESFNNLILAIGVGLSIAAMAIVSQFVGAK 97  Acholeplasma laidla...
EGM26528  19 LFKGLLILSIPIIINNLLQTMYNVVDTYWVSQIsnt-----dnEVAAVGGVWPINFFIIAFGIGLQIAGTSLMSQNIGAG 93  Haloplasma contract...
EEU99959  18 LSQAILMLAVPVMINSFIQSMYNLTDTFWLGRIgt-------eNQSAITLVSPFQNILNSFGSGITTAGAILISQYLGAR 90  Roseburia intestina...
ABX40768  15 LWKAILMLAIPIAVNNFIQTMYNLTDSYWLGKIgt-------dPQSAITVVTPIQSIIVNFGTGITVAGAILISQYLGAK 87  Clostridium phytofe...
ACL69241  16 IVKAILALAGPIMLNNLIQTIYNLTDTYWVGQLgg-------tEVAAITLIWPIVFFLLALGFGINIAGTSLISQYTGAD 88  Halothermothrix ore...
EEO35774  12 LYLSMIKLAIPLIISNFLQNLYNLADTYYMGKLgg-------iELATASFTSPITQMIIGAGTGFSLGGGVILSQTFGSK 84  Fusobacterium morti...
ADO83389  15 LYRVIFSIALPLMVSTLVQRAYTLTDMYFLGRLgs-------lQVAAITFVDPIITAILNMGLGLSVPMIATVSQSIGAQ 87  Ilyobacter polytrop...
O34474    92 NeERLKAVVGTTLTFTFLLGVVLAVIgSIFTLDIl-rLMGTPENVIHVSANYARILFYAMPFMFLYFAYTTFLRGTGDSK 170 Bacillus subtilis s...
ADO83895  90 DyNKAKNIAMQLFTVAVFIGIIITIVcFSFSKEIl-lAASATESIMSIANLYFRLTVLSSPFIFINSAYIAIKSANGDTL 168 Ilyobacter polytrop...
EFP59930  84 QkEDACRFATALLYFAIGFAILLSAGtLLLLHPIl-nWLDTPKEIYDDSYWYLFGISFDYIGLLMLNLYMAMRQSAGDSR 162 Erysipelotrichaceae...
ABX81111  98 ReDKAKFYAGQLLTIALIVGIALTLV-ILGFSWFfidLLGAKGQTFNFALEYFNIRSLELVGVIFFLVYQAIRQAQGSTI 176 Acholeplasma laidla...
EGM26528  94 RnDRANYIASQLYVFALIVGVIMAILgYTFSPLIi-kFMGFEGEIYELGLSYLRIIFFETPILFSFLIFMSMRQSQGDTL 172 Haloplasma contract...
EEU99959  91 KdEQANKMANHICITSLGFSLICALLcWLISPALv-tWLGARGVVYEYGLTYLRIVVLDMPFLFMINLFTAVKQAQGDTV 169 Roseburia intestina...
ABX40768  88 DeKNAKSMVGQLFASCMIFSVVCAAIcFLLTPALv-gWLAGGESFSSMAVTYLRIVILDMPFLFTINIFTAVNQSQGDTV 166 Clostridium phytofe...
ACL69241  89 DkENATRVSGQIVSFSLYFSIIIGIIgLFVAEPIi-kMMGGEGRLLELASNYLKIIFAGMPAIFLFLAFTSIKQGQGDTV 167 Halothermothrix ore...
EEO35774  85 NiKKLVEVNTQLIVVNMVIAIIITVLsFGFCEKIl-vFSGATGVLLEKSSLYIKFIFLTIPMTFIVTAYTVIKNSKGKTS 163 Fusobacterium morti...
ADO83389  88 KyDTAKKSIGNLIYVAFITSLIIGVSgLLFSTAIl-kLLNLEGRLLSLSSDYLKVVLLGTIFTFINTCYISIKQAEGDSM 166 Ilyobacter polytrop...
O34474   171 TPFYTLIVSTVINIALLPVLILgmfgfpKLGIYGSAYATVISTIATFLVLMVYLRKRKHPlqfdKTVRRYLKMDkelLVL 250 Bacillus subtilis s...
ADO83895 169 RSMNVNLVAMAIKIVLTYILIFn----fNMGIKSLAISTIIGTMFTSCYAVYDVFIRKTVm---KLSFKWPKLSkqvIIP 241 Ilyobacter polytrop...
EFP59930 163 SGVKLNTCASLFNAVLDPIFIFv----fHFGILGAAIATVVSKLIMVPFAWRRLHDKEFPv---HIDFRTYPFRpadGKM 235 Erysipelotrichaceae...
ABX81111 177 TPTLLNIGGILVNIGFTWYFVEv----lNWGVAGSAWATLIGNLIFVPLMILDLFISRRYm---RLKLSAFVPKkktLKE 249 Acholeplasma laidla...
EGM26528 173 TPVLFSASSVIINIILDPIFILq----fNMGVQGVALATVLSKVIVMPFALLVLFKAKKSv---HIVPKYMKLKfktIKR 245 Haloplasma contract...
EEU99959 170 KPMLLNLLGIMINLILDPLFLIv----fHFGIGGAAFATLIAKIPCALIGLILLTKSDQLi---RISFKNFVFDqkmIRA 242 Roseburia intestina...
ABX40768 167 RPMFLNLLGIVLNMILDPLFMLg----fGWGVAGAALATLLAKVPCAIIALYSLCNNKKSl---YITKESLKIQkdkLKS 239 Clostridium phytofe...
ACL69241 168 TPMKYSAISVALNMVLDPIFIFg----lDLGVRGAALATIFSRSVFAIYAIYTLFYRKTGi---QLHLKHLILKpnlLKK 240 Halothermothrix ore...
EEO35774 164 APLHLITVSVILNIILNSFFIYk----mNLGLKGIGIATVIANLLLCIYCLIDLSIKREI----AREYLKFNKDi--FKK 233 Fusobacterium morti...
ADO83389 167 KPLYMNVTALMLNILLNPIFIFq----mNLGIIGAALATVLSKCLLSIYGIWDTFKGSGL----KIEKKHLTINkeeFKR 238 Ilyobacter polytrop...
O34474   251 LLRLGVPASINMILVSLSEIAVISFVNHY-GSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEfDRLKQVIR 329 Bacillus subtilis s...
ADO83895 242 LFLIGIPIVIEKSSVAFSFIVVNKYVISF-GEKVLAGYGITNRINSLFFSAVAGFGTGLAPIISQNLGAGQeKRAKESIK 320 Ilyobacter polytrop...
EFP59930 236 ILKLCIPAASGQFLENLGFVIMNKYIVYY-GAIAISAYGVGAKLVTLAYIPVTSIGTILATFVGQNLGANNpERARKAFH 314 Erysipelotrichaceae...
ABX81111 250 IWPFAYPATVSHSVTFLGFLIINSFVLSQfGDVISASFSTGNKLSNLLMNPIYAITTIGAVFIGANIGNRQpERALKVYK 329 Acholeplasma laidla...
EGM26528 246 ITSVALPASVGTAFSSLGFIFLNGAIIGLyGKETMAAFTVGNRFISLIMMPAMGFGNALAFYVGQNIGANQtERAKASFR 325 Haloplasma contract...
EEU99959 243 IIKIGLPTAIGGSTMQLGTLIMTRNVNVY-GYIATSAYGIGNKINSLITMPASGVGSAVSTIVGQNMGAGNtERAKKTFH 321 Roseburia intestina...
ABX40768 240 IAKIGLPTAIGGSTMQLGFLLMTSSVIKY-GSTAVSAYGIGNRVNGLVTMPANAMGSAVATIVGQCIGARDqVRAQKAYL 318 Clostridium phytofe...
ACL69241 241 IIKIGLPSSLGQSSAALGFIFLNAFIISF-GKSTLAAFGIGNRINSVILMPAMGIGNALATIVGQNLGADQiKRARQAVK 319 Halothermothrix ore...
EEO35774 234 ILRLGFPSSLTTTTNSLSFILINIFVVKY-GNDVLAAYGVGNRINNIIYVLVNGIGSSVAILVGHSIGAGKiKEIREILL 312 Fusobacterium morti...
ADO83389 239 MVALGLPAIITKIASPLGNMLINSQALSY-GPALIASVGLGNKINSIVFSLNSTLCTAMTTITGQNLGNKTpERIKEAFK 317 Ilyobacter polytrop...
O34474   330 VGIWLNYIIGGVLIIL--IYVFSHQILSLFLt--EQETLyIAHRLLMITLWSYLLFGNAQIIS-ATMRASGTVlWPTVIS 404 Bacillus subtilis s...
ADO83895 321 KTYLTALVISCAVISI--VLPFKYSLAGVFSn-gDSAVLyHTVNAISVYSISVIPWAIFQVTS-GIFQGTGHTkYNMFIS 396 Ilyobacter polytrop...
EFP59930 315 TAMKLSTLFSSALTII--GMFAITPFIHIFVpnaSIQLVeLTREYALFALLCGVFMGWYINLNdGVFNGSGHTnYTFILS 392 Erysipelotrichaceae...
ABX81111 330 QSGRMTFTITVVAILV--AILFRKEFVTLLVgtqNDRLIeVSVEYTLWLLLTQPVMSIFQNYM-AIFNGSGQSkLGLKAQ 406 Acholeplasma laidla...
EGM26528 326 TSITLTLSFMFVGMLIllPYNTRSFAVNIFLk--EKRTIeLAMTYMLFIALNVPLMGLFANFN-GVFQGSGKTwFVLIMN 402 Haloplasma contract...
EEU99959 322 YSLKMCTLFLLILGFIfsRRPVSQTMVSFFSt--DAKVIpLAADYLSIIAFWCFTNAFYNVSQ-GLFQGCGHTlITMLVD 398 Roseburia intestina...
ABX40768 319 MARRIAVIFLFIGGLIlsRNTVSEPIVRIFSn--DPDVIrLGTQFLQLMAFWCFTNGIYTTTN-GLHQGSGHTmINMTID 395 Clostridium phytofe...
ACL69241 320 TSAVLTTVLLTSGGII--LYPFVPTIIRAFNt--EPAIVsQGTFYLRLISLSLPLMGFFQIFV-GTFQGSGHTlMAMFIM 394 Halothermothrix ore...
EEO35774 313 AGIKIGLIVGIVSVIF--LYWNLDIAVGILTs--DEMIKyHSINYLKIMLISVIPWVIFQVLA-GVFQGTGHTtFNMYCH 387 Fusobacterium morti...
ADO83389 318 KMLMLIFFLGTLGLSV--VLLFSKEIVGLFSn--DPEVIkTTTEFLRVTFPTVFMWGIYQAIS-GIYQGAGYTkISMYIT 392 Ilyobacter polytrop...
O34474   405 IFAIWGVEVPVAFVLSHyt-klEILGVWVGYPAAFAVSLLLIYGYYQFVWKK 455 Bacillus subtilis subsp. subtilis str. 168
ADO83895 397 IMRIYCFRLPLIIIFTKft-dmSEYSIWYGMLLSNILTGFFAMGLYYINCKN 447 Ilyobacter polytropus DSM 2926
EFP59930 393 MMRLWAFRIPMILLFHRft-hfGITGIWLAMLLSNIFECILAQSIYLRHTWE 443 Erysipelotrichaceae bacterium 3_1_53
ABX81111 407 SFRLWGLRIPLLFGLWFlfpemKYSVVWTAMNISNVIALFHAHYLRKNIELD 458 Acholeplasma laidlawii PG-8A
EGM26528 403 ATRLWIFRLPVIYLLYHit-dlGPTGVWYAMVLSNVIICIIGTFLYKFGHWE 453 Haloplasma contractile SSD-17B
EEU99959 399 ASRIWLFRLLSLWICANvf-hmGVASVWYSVVISNGTSAIILYLLYWTGIWK 449 Roseburia intestinalis L1-82
ABX40768 396 ATRLWVFRLATLFICERll-hmGVQSIWYAVVVSNGISAVILWIIYKMGVWK 446 Clostridium phytofermentans ISDg
ACL69241 395 TGRLWALRIPLIILFKKyt-dwGSSSVWYAMVLSNAIISLVGFIMYLTGKWQ 445 Halothermothrix orenii H 168
EEO35774 388 VGRIWIFRVPFIYFLERil-elKEYSIWYSMLLSNLCALLFSIFLYRKIDWK 438 Fusobacterium mortiferum ATCC 9817
ADO83389 393 LIRLWIIRIPLIFILAVf---iGEKSLWYSTAIATNSIGVIAIIFYLSNSWM 441 Ilyobacter polytropus DSM 2926
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