Conserved Protein Domain Family
GsiA

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COG1123: GsiA 
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 440740
Aligned: 794 rows
Threshold Bit Score: 252.132
Created: 9-Feb-2022
Updated: 24-Feb-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
BBD54272       1 MpSLFDVEHLRVAYPhsrKA---QIWAVDDVCFSLQPGERLGLVGESGCGKSTIGRAVMRLL-PttsQIEGQVRFEGQPV 76 
NP_460225      1 M------------------------------------------------------------------------------- 1  
WP_089133839   5 L-PVLSLKNVSKSFV---DGsgtQTDVLDKINLDVADGEFIAILGFSGAGKTTLINCIAGLT-E---ANEGEVLVKGEPC 76 
WP_012178337   1 M-TAIEFKNVSKSFG---SGp-nRADVLRDINLTVKEGEFLVLLGFSGTGKTTLINLMAGLEvPt----KGEVLFKGAQI 71 
WP_012865545   1 M------------------------------------------------------------------------------- 1  
WP_025801253   1 M------------------------------------------------------------------------------- 1  
WP_015871071   1 M------------------------------------------------------------------------------- 1  
WP_005315122   1 M------------------------------------------------------------------------------- 1  
WP_087471164   1 M---------ST-------------------------------------------------------------------- 3  
WP_106910776   1 M------------------------------------------------------------------------------- 1  
BBD54272      77 FGmdekrlqkfrGEAVALVFQDpmTRLDPLmTIGDHCLETLKAhRp-QLSNSQAKNKALEVLESVKIpANRWSQYPHEFS 155
NP_460225        --------------------------------------------------------------------------------    
WP_089133839  77 KGp---------SKDRGLVFQS--YSLFPWlSVQANVALAVDA-VhqDKSKEERAALVKQKIELVGL-DHAMDRKPAQLS 143
WP_012178337  72 TEp---------SPERGVIFQN--YSLMPWlTVNGNVRLAVDT-MfpKLSKAARQAKVDHYVKMVGL-CHATTRRPAELS 138
WP_012865545   2 -------------------------------------------------S------------------------------ 2  
WP_025801253     --------------------------------------------------------------------------------    
WP_015871071     --------------------------------------------------------------------------------    
WP_005315122     --------------------------------------------------------------------------------    
WP_087471164     --------------------------------------------------------------------------------    
WP_106910776     --------------------------------------------------------------------------------    
BBD54272     156 GGMRQRVAIALALLLDPKLIVADEPTTSLDVTVSAQILQELTRLCEQRGTAILLISHDLAMVGEYCDRIAVMYQ-GKMVE 234
NP_460225        --------------------------------------------------------------------------------    
WP_089133839 144 GGMRQRVAVARALAMEPEILLMDEPLSALDALTRAKLQDEIERIRKHEKRTIVLVTNDVDEALLLADRVAILTP-APsAT 222
WP_012178337 139 GGMRQRVNVARALAMNPEVLLLDEPLSALDALTRANLADEIEGIWEKEKKTCVLITNDVDEAIVLADRIIALNpdGTL-- 216
WP_012865545     --------------------------------------------------------------------------------    
WP_025801253     --------------------------------------------------------------------------------    
WP_015871071     --------------------------------------------------------------------------------    
WP_005315122     --------------------------------------------------------------------------------    
WP_087471164     --------------------------------------------------------------------------------    
WP_106910776     --------------------------------------------------------------------------------    
BBD54272     235 MGASETV-FQNPQhpy-------tqSLl------------KS---------ALH-----LQ-Dienkavn-sgletsTSA 278
NP_460225        --------------------------------------------------------------------------------    
WP_089133839 223 IGKIFDVkIDRPRereamnddaaykTLrntivgyldilshDQkaiasdfanLPDikpldLSgAqevertnlpqayldAAQ 302
WP_012178337 217 -GDEFAVtIPRPRdrvemnthvgfkKLraditkylmdvgiEAkveg--tklLPDvtpihgv----------paaiakAQA 283
WP_012865545   3 -------------------------------------------------------------------------------T 3  
WP_025801253     --------------------------------------------------------------------------------    
WP_015871071     --------------------------------------------------------------------------------    
WP_005315122     --------------------------------------------------------------------------------    
WP_087471164   4 -------------------------------------------------------------------------------T 4  
WP_106910776     --------------------------------------------------------------------------------    
BBD54272     279 TKPL----LSIKNLQ--K-YYTLEagfiqqlfsklsiknlqkyytleagfiqqlfskqKKSVIKAVDGINLELYPGE-IL 350
NP_460225      2 --------LSLQQVTleSaRY--Rwy-------------------------------gARRWSPLLQNVSFDIAPGE-MV 39 
WP_089133839 303 S-PIttryLEFFKLK--K-IYPT-----------------------------------PKGPLTVVEDVNLLMDKGE-FI 342
WP_012178337 284 G-MLnerfLDFSQLH--K-VYPT-----------------------------------PKGPLTVVEDFDLKLNKGE-FI 323
WP_012865545   4 QKSV----LTATNLS--A-GY---------------------------------------GGTPVIRDVSLTLTGGGaPI 37 
WP_025801253   2 --------LNFDNVTieSaRY--Swl-------------------------------gRKKWSPILSDINLTLRRGE-VV 39 
WP_015871071   2 --------LSFHNITleAaHY--Rwy-------------------------------gARCWSPLLQGITLDVAPGE-LV 39 
WP_005315122   2 --------LSFDHVTieAaHY--Swl-------------------------------gRRSWQPLLTDISLQLAPGE-IV 39 
WP_087471164   5 TTPI----LRATGLA--A-GY---------------------------------------GGPDVVHGIDLDVVPGApPV 38 
WP_106910776   2 --------LQLKQFGveTaTY--Rwf-------------------------------gRPRWQARLQDINLQLHPGE-LV 39 
BBD54272     351 GLVGESGCGKSTLSRTILQLIR---ATN---GSVE---FLGTDLTKLSSEQVRKY-RR-QMQMVFQDPNA--CLNPMMTV 417
NP_460225     40 ALVGGSGEGKSLLLQCLLDLLPenlRFR---GEIT---LDGNRLDR--H-TIRQL-RGnTFSYVPQGVQ---ALNPMLNI 106
WP_089133839 343 SLIGHSGCGKSTVLTMAAGLNE---ISD---GGII---LDGREIDV------A---GP-DKAVVFQAP----SLMPWLTA 399
WP_012178337 324 SLIGHSGCGKSTVLTMAAGLNE---ISK---GAIK---LDGRHVEG------A---DP-ERAVVFQSP----SLFPWLTA 380
WP_012865545  38 GVIGQSGVGKTTLIHALVGVLK---PSG---GRVT---FNGRTVNKLALGAKKNF-GV-SVRRVQQNGFT--GLDSRLTV 104
WP_025801253  40 ALVGGSGEGKSLLLQSALALLPqnlRKR---GDIC---LNGDVLNT--Q-QCQKL-RGnTLCYVPQGVS---SLNPLLNV 106
WP_015871071  40 ALVGGSGEGKSLLLQCALDLLPvnlRSH---GTLS---LDGKPLSA--D-GRRRL-RGhTLCYVPQGVS---ALNPLLNI 106
WP_005315122  40 ALVGGSGEGKSLLLQSALTLLPdnlRMR---GTLS---LDGVPLCD--A-SRARL-RGhTLCYVPQGVS---ALNPLLTV 106
WP_087471164  39 GIVGESGAGKSTVVRALVGLVR---PTA---GHVT---YAGRTVTKLSRRDKKQF-TA-DVRRVSQDGLAgiGIDPRWTV 107
WP_106910776  40 ALVGASGAGKSLLVQGLLDLLP---PHTrrtGKICiteLTGSAQSA--S-GKSPApHR-LFSYIPQSVA---ALNPLRTI 109
BBD54272     418 GESIADPL-FIH-KLATPEEAKNQVLAMLERVGLT-PaiEYYQRYGGELSGGQQQRVAIARALMTRPQLLICDEPVSMLD 494
NP_460225    107 RKHLNRAC-HLT-G---RAWDETQMVQLLQQSDLE-P--TVLERFPRQLSGGMAKRILACHASLSQARYILADEITAWLD 178
WP_089133839 400 RQNVALGVeRVYpH-TSRSERKDIIEYYLDRVGL--G--DAMDKMAADMSNGMRQRVGIARAFALSPKLLLLDEPFGMLD 474
WP_012178337 381 RENVSVGVdRVYpN-ASQAERQDVVEYYLERVGL--A--DSMSKSGAELSNGMKQRVGIARAFALSPKLLLLDEPFGMLD 455
WP_012865545 105 RKALEAEL-AKA-RK-AGRATGGTVEDALATVLLE-N--RYESRTIGTLSGGEKQRLALASALATRPDVLILDEPTTALD 178
WP_025801253 107 GTQLSRSL-HLS-G---SHTCALALEQQIKHYQLQ-A--DVLLKYPRQLSGGMAKRVLACNAALGGAHYILADEITAWLD 178
WP_015871071 107 ERHLQRTR-HLA-G---QHWDAEQASAVLRQSHLDpT--TVMHSYPRQLSGGMAKRVLACHASLSHARYILADEITAWLD 179
WP_005315122 107 ERQLGRAA-RLC-G---QNGSRERLGEQLQRYQLP-A--ATLDRYPRQLSGGMAKRILACTAALGGARYILADEITAWLD 178
WP_087471164 108 DRTLSAAL-KDA-RR-AGRPSGRSVEDLLGDVALD-A--RYAPRTIHSLSGGEKQRVALAVALATRPRALLLDEPLTAVD 181
WP_106910776 110 GAQLQRAG-ELA-G-IPSSQREPHIASLLQRHQLD-D--GIQQLHPHQISGGMAKRTLICCASLHHSRYLLADEVTAWLD 183
BBD54272     495 ASIQAQVLDLMLELKQEFNLTYLFITHDLWVARFLSDRIAVMNGGKIVELGETESI-FT--NPQ-----------HPYTQ 560
NP_460225    179 TALANQLLEHLRGLCER-GCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCEQL-QP--EEM-----------SEPLK 243
WP_089133839 475 SLTRWDLQDVLIEVWNRTKVTAIMVTHDVDEAILLADRVVMMTNGPQATIGKILDVdLP--RPRdrkallehpkfYAYRQ 552
WP_012178337 456 SLTRWELQEVLMEVWSRTKVTAICVTHDVDEAILLADRVVMMTNGPRATIGKITDVnLP--RPRtrkallehpdyYTYRQ 533
WP_012865545 179 HTLRLELGRRISEIVAEQKIGLLLVSHDLEMIARICSTVHVLSDGTFVETGTPEQL-FN--NPH-----------HPVTR 244
WP_025801253 179 EPLACQLLQQLRDLSAQ-GAGVLWVTHDLSLAVRFADRIVALNEGRLSDDITVADL-KN--GFG-----------SPTLQ 243
WP_015871071 180 AALAHQLLRQLRHLCKQ-GCGILWVTHDLMLAAQHADRIVALHQGQVSDSVSRAQL-QR--GEI-----------SERLM 244
WP_005315122 179 EGLACLLLGQLRELANQ-GSGILWVTHDLALAARFADRIVALHQGQVSDTLSSHHL-RQ--GQG-----------SEMLR 243
WP_087471164 182 PAMRGDVVRRLGDATAELGTAVLLVSHDLELVERLCPTVHVLADGTFVTSGALRDV-FAgtAPGa---------dHPSVR 251
WP_106910776 184 DDNARATLRHLRERCEA-GCGVLWITHDLALAAEYADRVAVLHAGRLVETLSSTEL-RR--GGG-----------SAYVQ 248
BBD54272     561 TLLSAI--------PS----L--------A--K---T 572
NP_460225    244 RQWQAL--------PEln-pLfmptgegiEc------ 265
WP_089133839 553 EVLQFLaeye-hgnPNk--sAq------qE--Aa--- 575
WP_012178337 534 EVLDFLeeyehgakPRk--pApa-----pE--Piaae 561
WP_012865545 245 EIAIAM--------PKa------------SgmP---E 258
WP_025801253 244 KHWLAQ--------PEhh-lLfph--taaDn----fT 265
WP_015871071 245 RQWQAL--------PErg-tLf------sDlerapc- 265
WP_005315122 244 AHWQAL--------PEfn-sLf------sV--Pe-vS 262
WP_087471164 252 GLAEAA--------PL----Av-------Qrfr---- 265
WP_106910776 249 ALWQAL--------PQhgfhVs-------D--PaqlK 268
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