Conserved Protein Domain Family
VgrG

?
COG3501: VgrG 
Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly [Intracellular trafficking, secretion, and vesicular transport, Mobilome: prophages, transposons, General function prediction only]
Statistics
?
PSSM-Id: 442724
Aligned: 584 rows
Threshold Bit Score: 199.603
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_109038030   18 MTDHsgiqhalgdaarsvldgllaelsafgpsqhTRLLRLHtp-lGpd--vLLAERVQIHE-GMgpgaallpdtldhsvd 93  
WP_025330507    1 ---------------------------------mQQRYYLKlnanLanfdqFSVRRFNLEE-KL---------------- 30  
WP_040199608    3 FISaawdas--------------------shradAQQYFFRvqgvPdg--tLAVKDFSGSDhGL---------------- 44  
WP_052464882    1 ----------------------------mssifnsARLSVEvgglDl-----SALALSGRE-GL---------------- 30  
WP_044619535    3 QSTapivhaa-----------------rqilgadSSQFFLKvgdlSgd--sFLVESVKLQHwRF---------------- 47  
WP_053551937    6 LAAgkida-----------------------panrsQFACSvrgiPde--tFSVRSFSGKGhAL---------------- 44  
WP_082829690   19 MPMDvpikhphh--------------arssrvapGLTLRLTl---Ggl--dLPVVALRLRE-GL---------------- 62  
WP_082829757  320 MPMtpmtp-----------------------mtqrpRLQLDlqcqGge--rLTVLDFSSQDlAL---------------- 358 
WP_089084658    1 MQQasppvawam-------------atpikddlmPNPYQLRfsshLgl--dLSVHHFTLDE-AL---------------- 48  
WP_089085182    1 ---------------------------------mHNPYQLSfpsrFql--aPSVHTFQLAE-AL---------------- 28  
WP_109038030   94 lhpaqpveppPTGQRTELLALStRAD-LAPEDLLGHPILLELLT---Ag------------pGGALRPFHGHVTAFELL- 156 
WP_025330507   31 ----------DDYYVLQLEATHmAAD-LPLENFIHQRVMFEMAPdidWsgvmqvs--rqqlddSDNRRWHGVIQSAEQI- 96  
WP_040199608   45 ----------SQDYCFTINLFSe-SF-LDVGLAVGRKGTLEMAW---E--------------GRMLP-LHGVVSEISYV- 93  
WP_052464882   31 ----------SQPFCYHLDILTa-PE-ISCAQLLDLPARISIVG---S--------------DGGCRIICGVVTSLEEKd 81  
WP_044619535   48 ----------HQDFTLKLKVLAl-KD-IDDTTLLHAATTFQLq----T--------------GGSLKPLHGLITEWTDA- 96  
WP_053551937   45 ----------GGDYRFRIELLAs-SA-IDTTYIIGRPAALHLA----P--------------GGEVP-IHGVILEVAYG- 92  
WP_082829690   63 ----------SRITRMEVDVIHsGPAcL---ERLGSSARLMLSA---A--------------PGPVRDWQGILMACRPS- 111 
WP_082829757  359 ----------SRSYRLDVRCHSh-SP-LVASEVLGQAACLRLD----R--------------GSAAPCIHGLVTALDQSp 408 
WP_089084658   49 ----------DTPYLLNVTVTSpDPA-LALASLIHQPVSFTISPppaQslpvisglpafpanpAAQRVWHGVVCEAWRE- 116 
WP_089085182   29 ----------DTPYQLRVAVTLqDSD-LPLAPLIGQPVTFTISPqstAppltipgleplvstlAGQRSWHGVIRHAQRG- 96  
WP_109038030  157 G-ADG-GHARYRLRIEPWLAFLGHRTDAWVFQDMSVLDITEAVFADY-A-AqgklmpaWRfDLAdrsvYARRSLCVQFNE 232 
WP_025330507   97 A-TSA-DETCYRFTIVPRLALLNRITTTRLFQNETALSIVEKILRHH-G-Fas---edFLlKSSr--sLPRYEHRMQYRE 167 
WP_040199608   94 G-EAV-GGHAYVVRLNSVLHPLKLRRDNRVFLNTTAPQIIEEILQGA-G-Fse---tdYElELDg--dYPFREFVVQYDE 164 
WP_052464882   82 P-HHD-GCRCFSLTVESSLARLRLQHDTRIFLHQSLPQILRAVLASH-G-Ivd---drLRlRLSr--hYPVQPWTLQVNE 152 
WP_044619535   97 D-GNG-DYRGLQLTISSVLNPLRHQQHNRVFVDRSATDIAEELLQNSlGdLag---vdV---LCq--tSPVLPMTVQYHE 166 
WP_053551937   93 G-AGA-NGHEYQVEFASPLAPLGMGRRHRVFLGKTAPKIIEEVLLGG-G-Faa---gdFElRLKe--nHPAREFTVQFDE 163 
WP_082829690  112 GmAEDvG-RRWRLSLRSRLAGLTLHRHTRLFTGLDAVDLARELLEPL-G-Vav-----dAgHLTl--dHPRRGAILQADE 181 
WP_082829757  409 G-AAG-KGVIQHICLESPLAPLARTRQNRVFPGMGVRAVVEEVLQGH-G-Wtp---aqWRmACRd--dDPVEDLIVQVEE 479 
WP_089084658  117 D-SNV-QETRYRFAIGPRLRLLAEGATCRLFQNSSVPQVIAAVLQQH-G-Faa---sdMRfQLTt--pLPTHAHLTQWRE 187 
WP_089085182   97 R-STP-EETLYTFEIGPRLALLEDSRSTRLFQNMTVAQVMEALLRKH-G-Lds---sdFSfQLTg--aQAVYEHLTQFRE 167 
WP_109038030  233 SDLAFLQRLWAEEGLFTWFEHEgrptdvphlgrhTLVIADHNGAFrpn-aqARVRFtq--aGAvm--------------- 294 
WP_025330507  168 TDYAFIKRVLAREGLWFTFTQTas--------neVISVADDVSHYiql-rqQALPFkp-daGLesdlegleskleaqlsf 237 
WP_040199608  165 SDWDFLLRICAHVGIFFRFSQNge--------gvRIVFHDRVDDLpac-acGELLYev-qsGTrr--------------- 219 
WP_052464882  153 SDFDFISRLLARAGIFYWSEAGtd--------geLLCFSDHNGNLcer-pgAALQYrp-gaGMepe-------------- 208 
WP_044619535  167 SDYDFIRRILAKEGVFLNLHQDdt--------rtIVQLSDDLTQLpeheitINQRFat-naGAak--------------- 222 
WP_053551937  164 SDLAFIKRLAAGAGIFFRFEVGss--------gsRLLFHDGVGDLphl-gsGPLRFql-qtGAvr--------------- 218 
WP_082829690  182 SDADLLFRVLARAGIHTRLAAVeg--------meTLRLADGMDASep----rVLDWlgpsrGWg---------------- 233 
WP_082829757  480 DDLAFITRLMAFHGLFYRFEQSrq--------gvTLVIHDDACDLpea-pvRRLPFha-hsGQha--------------- 534 
WP_089084658  188 SDLQFISRLAAEAGLFYQFVVEeag-------keVLLFGDNLEHYgrg-rlLDIPLra-pgGLrqd-------------- 244 
WP_089085182  168 TDLAFLCRIAAHAGIFYQFIQGkdg-------keIIQFGNNLEHYtrg-hlENIPLre-haGLesv-------------- 224 
WP_109038030  295 ----------------------keDs---LTRWHGLRRIGPAALHTASFDYR-AVANh-gASAT--SDDahgqpfDlvHA 345 
WP_025330507  238 dvnataqgikdnlkqqlmqglmakYs---VSEFHVRYKAQYESVQIKDYNYR-DANNsllGKAG--FNEqqp-aaFgqPY 310 
WP_040199608  220 ----------------------grEt---VFALRERSNLLSAQVELKDYNDQ-TPEAhlsAHAS---Ssg----gNgrDY 266 
WP_052464882  209 --------------------------scgVRALQVRRRMVADLFEVQEKSRL-QPSCslyAQAS--NGgq----gRmrRY 255 
WP_044619535  223 ----------------------ddTh---VSAVIQNQQHHLSQVVLNDYQPW-VSASlmtDASL--GTaq----gIgtSE 270 
WP_053551937  219 ----------------------deEt---IFAFTPRARLLSQKVELRDYNDQ-TPEVvleAYGSpgTAva----gAgtDY 268 
WP_082829690  234 ------------------------DrapgVLSAREHHRQVCRQIRVRGRLADgRPCEtl-aD----TGHgeg------iq 278 
WP_082829757  535 ----------------------paDi---IYRLAARARLMPGAVQLRDHFPD-HPQValhARQE--CKql----sGglED 582 
WP_089084658  245 ----------------------drPa---IQQWQIHQRSMLHSVRRTDFNYL-TADTvldAEHG--LGGpqp-aaYglDY 295 
WP_089085182  225 ----------------------gtEa---VTAFSIRHSPMLHTTRRRNFNDM-AASPlpdGSAG--FACevp-aaHgeDY 275 
WP_109038030  346 DQPGayayeTPAQAERRAWVQMQSLDAARKRFVGEGTVRTLAPATTFTLL--EHAEhdagllsaG-S-TENQFVVLGVVH 421 
WP_025330507  311 IY-GffhhkDSGQAQEYARILHEHSVSRHILATGKSNVQSFAPGFTMGFS--SDAR--------V-G-NIRQWLLVSVHH 377 
WP_040199608  267 RY-Geh-flDLEQGQQLARMRGQLLDWQRRTLVAETDCRALAPGEILSIT--GHSD--------E-G-LNGDYLIVELEH 332 
WP_052464882  256 RY-Atg-veDLNEAEQIARTEAQQAKACSFELQAQTDVADLRVGQVISLD--AGVF--------LqQ-YGDDYLVQEVSL 322 
WP_044619535  271 HW-Gln-ydSSDSGRQLATRMAQVHDWQRQTLTIRTTSREFSPGMLLQLT--DHPR------------FSGDYRVIDVEY 334 
WP_053551937  269 RF-Geh-frDMAEGAALARIRQQALDCQRETFVAESDCRGLSPGLRITLT--GHPE--------S-G-NNGDYLVVDVEH 334 
WP_082829690  279 DHPGwg-lhDSRSLEwRARFLAQREACRARTLLLETTVPDLEPGERVRISapDHP-----------SvPSGVWRVESVLH 346 
WP_082829757  583 HW-Gag-faTPGQGEHLARVRAESLDTQSLSFSAWTGHRALTPGQRITLT--GHPH--------A-D-FNKTYTITALQL 648 
WP_089084658  296 AW-Geg-grDAAETARIALLRHQASQARQCVASGSGTVLHIRPGEVLRLD--H-AF--------A-E-AEHGWLIIAARH 360 
WP_089085182  276 DW-Gdd-nrDDEESAQLARLRHELSVSRQCIASGDSNVSRLSPGAVLTLS--H-AF--------A-D-APHGWLISSVTH 340 
WP_109038030  422 EARNnlsadaqaglkrllgdavlgalaavaegeaqanasdAPLYRARLTAQRHSVpvrAPMrgadgrlLHrRPVVHGAQT 501 
WP_025330507  378 sg------------------------------------arDEDYINSFSAIPSDSqwrPEP--------IkHPIIDGTIP 413 
WP_040199608  333 DGDQsagfaf-------------------------gdsgkGMSYRNRLLLTRAGTpyrPPL-------PAaR-PMHGLLT 379 
WP_052464882  323 QLSQragaq---------------------------aagdDLALNCEANLIPREIpfrPPW-------PT-RPRIPFTFS 367 
WP_044619535  335 SGSQraas----------------------------ggsnDKGWSCDLIVLPADLpwcPPY-------APrQPH-YAAMS 378 
WP_053551937  335 AGEQgaafay-------------------------ggspgRMTYRNKALLVRDGVay-rPV-------PIpR-RLHGTYT 380 
WP_082829690  347 RVHSda--------------------------------sgRwAYRNRVRLCPGDAsyrPAEpr-------rHGAVPDMLQ 387 
WP_082829757  649 RGEQasslpd-------------------------gmpttGPAFSTRLELIPSTQsyrPPL--------TpH-RSSARFV 694 
WP_089084658  361 qg------------------------------------arDQAYHNRFQAIPADRiwrPAL--------LpKPRIYGTLP 396 
WP_089085182  341 sg------------------------------------srDRAYQNSFHAIPADRvwrPAL--------TpKPRIHGTLP 376 
WP_109038030  502 AVVVgl--gEPvh---tDRDGRVKVQFHWQrgaqgshrlsapaddnapASAASGTWVRVAQDWS------GQ----NWGS 566 
WP_025330507  414 GTICda-gqGPya--wvDEMGRYIVKFNLDmd--------------gwQPGGESRPIRLAKPYA------GG----QYGQ 466 
WP_040199608  380 ARIEtt--gGEya--ylDEQGRYRLRTDFDls--------------etAPGEASHPVRMVQPYA------GR----DYGF 431 
WP_052464882  368 ARIEg---sGTya--plDEQGHTPVRAHFDqg--------------aaALGEASIPLHRLAPLG------GPpgeqACGW 422 
WP_044619535  379 AVIte----------eiDDNGCYRVRLPFDrr--------------anSEGPASPPIRLMQPLG------GS----DHGM 424 
WP_053551937  381 ARIEss--gGEya--flDEQGRYRIRADFDlg--------------daQKGSASHPVRLMQPAG------GD----NCGL 432 
WP_082829690  388 ARIQglngpDQ------DEAGRQRARGLFEdag-------------lmEPDRGPRWARLt-PYAappgqdGQ----ASGW 443 
WP_082829757  695 ARIDgp--eGEpi--hlDAHGRYRIRFDFDsr--------------ehPPGQASHPVRMLTPYA------GD----DFGF 746 
WP_089084658  397 AMVVsp-gdNSyrypflDELGRYRVRFLFDld--------------rwSPGGDSRPVRLAKPFA------GG----GFGF 451 
WP_089085182  377 AMVVsp-gnNSyhypfiDEHGRYRVRYLFDld--------------swSPGGDSRAVRLAKPFA------GR----QFGF 431 
WP_109038030  567 VFIPRLGQEVIVSFVDGDID-RPVVVGAAYNGQGAddaqgnqvaagsatatgnapaWFpgsqkageleghaHTATLSGFK 645 
WP_025330507  467 HFPLHVGTEVQLAFQNGDPD-RPYIIGVLHTSTQpd-------------------hVPn------------TWRTRNVIR 514 
WP_040199608  432 HFPLHAGTEVVISCVNGDLD-RPVILGALPNPDTpt-------------------pVTs------------ANRTQNILR 479 
WP_052464882  423 HSPLRDGAEVLLSCLNGDPD-RPVLMGALPNPATps-------------------pVTg------------DNPAQNILR 470 
WP_044619535  425 HFPLAKGTEVSVLWENGDLD-RPYIQGALYNGQAen-------------------pVTd------------ANARQNLIR 472 
WP_053551937  433 HFPLHPGTEVVFTCINGDID-RPILLGVLANPDTps-------------------pVTs------------ANSSENILR 480 
WP_082829690  444 HAPLHPGQPVSLMILGGDPDgFAVIAGAGFDGAHAn-------------------pVNa------------RDDTANRYR 492 
WP_082829757  747 HFPLHAGTEVLVAFENNDPH-RPIILGALPNADHps-------------------pVTa------------HNRHQNLLR 794 
WP_089084658  452 HLPLHAGTRVNLGFDDGDPD-HPYIASVLHDSSKpd-------------------hIDs------------GWHTRNVIL 499 
WP_089085182  432 HMPIHAGTIVHLAFSDGDPD-HPYIAAITHDSERpd-------------------hITt------------QWNSRNVIR 479 
WP_109038030  646 SQAldasktGggghNQLVLDDTPGQGRLLAHTTQHQTWLqighlLQQHDN-----QRlahrghglELHTLAQ-GALrAAS 719 
WP_025330507  515 TWAn----------NKIRMEDLSGHEHIKMATEYHKTQLnlghlVDSGRD-----KRge----gfELRTDGW-GALrSaR 574 
WP_040199608  480 TWGg----------NELLMDDRAGREKTELFTRERKNILsldadCDGhr---------------vRLASEEGeMEVyAaK 534 
WP_052464882  471 TAAd----------NQLLMDDRREHEVIGLSTFAGNNILelnatALGhr---------------iALASHQGaMQIrAeK 525 
WP_044619535  473 TRGd----------HRLLFDDTPDQEHIHLTTPEDQNHLtlsaaSEGhf---------------aELVSEQGeVRLrAgK 527 
WP_053551937  481 TKGg----------NELLMDDRRGKEKVELFTAERKNLLaldadSEGhr---------------vRLASEEGtMELfAak 535 
WP_082829690  493 Sa-------Gg---HTLLMDDREGRALLRLFTRDEQHLLal--dAHADAatlsliCRqg-----alI------ATT--Gg 547 
WP_082829757  795 THGg----------NELLMNDQPHGPGIRLSTRDHGLRVlmdatPEDph---------------lALHADDGrMLWqAgQ 849 
WP_089084658  500 TRSh----------NKLRMEDLQGKEHIKLATEYGKTQLnlghlVDAQRQ-----PRga----gfELRSDQW-GAIrAgK 559 
WP_089085182  480 TKAn----------NKLRMEDLQGKEHIKLASEYGKSQLnighlVDAARA-----PRge----gfELRTDHW-GAIrGgK 539 
WP_109038030  720 GLHL--SSFa----RpGG 731 
WP_025330507  575 ALYL--TTEnqaaaNgMQ 590 
WP_040199608  535 TMLLesgdsqfvevgkdq 552 
WP_052464882  526 TQKI--QCg-------DS 534 
WP_044619535  528 SATF--ESg-------ED 536 
WP_053551937  536 tllldsgetqtveaggdh 553 
WP_082829690  548 cLHIrcGGDld--aRagg 563 
WP_082829757  850 SLSL--QTg-------GD 858 
WP_089084658  560 GLLL--SAYsqrkasglq 575 
WP_089085182  540 GLLI--SAEaksvaAtPQ 555 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap