7CVY


Conserved Protein Domain Family
Alpha_E2_glycop

?
pfam00943: Alpha_E2_glycop 
Click on image for an interactive view with Cn3D
Alphavirus E2 glycoprotein
E2 forms a heterodimer with E1. The virus spikes are made up of 80 trimers of these heterodimers (sindbis virus).
Statistics
?
PSSM-Id: 425959
Aligned: 4 rows
Threshold Bit Score: 734.818
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
7CVY_B   10 PYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIGTDDSHDWTKLRYM---DNHIPADAGRAGLFVRTSAP 86  
P03316  339 PYLGTCSYCHHTVPCFSPVKIEQVWDEADDNTIRIQTSAQFGYDQSGAASANKYRYMslkQDHTVKEGTMDDIKISTSGP 418  Sindbis virus
P03315  347 PYIAYCADCGAGHSCHSPVAIEAVRSEATDGMLKIQFSAQIGIDKSDNHDYTKIRYA---DGHAIENAVRSSLKVATSGD 423  Semliki Forest virus
Q8JUX5  339 PYLAHCPDCGEGHSCHSPVALERIRNEATDGTLKIQVSLQIGIGTDDSHDWTKLRYM---DNHIPADAGRAGLFVRTSAP 415  Chikungunya virus s...
7CVY_B   87 CTITGTMGHFILARCPKGETLTVGFTDSRKIShSCTHPFHHDPPVIGREKFHSRPQHGKELPCSTYVQSNAATAEEIEVH 166 
P03316  419 CRRLSYKGYFLLAKCPPGDSVTVSIVSSNSAT-SCTLARKIKPKFVGREKYDLPPVHGKKIPCTVYDRLKETTAGYITMH 497  Sindbis virus
P03315  424 CFVHGTMGHFILAKCPPGEFLQVSIQDTRNAVrACRIQYHHDPQPVGREKFTIRPHYGKEIPCTTYQQTTAETVEEIDMH 503  Semliki Forest virus
Q8JUX5  416 CTITGTMGHFILARCPKGETLTVGFTDSRKIShSCTHPFHHDPPVIGREKFHSRPQHGKELPCSTYVQSNAATAEEIEVH 495  Chikungunya virus s...
7CVY_B  167 MPPDTPDRTLLSQQSGNVKIT-VNGRTVRYKCNCGGSNEGLITTDKVINNC-KVDQCHAAVTNHKKWQYNSPLVPRNAEL 244 
P03316  498 RPRPHAYTSYLEESSGKVYAKpPSGKNITYECKCGDYKTGTVSTRTEITGCtAIKQCVAYKSDQTKWVFNSPDLIRHDDH 577  Sindbis virus
P03315  504 MPPDTPDRTLLSQQSGNVKIT-VGGKKVKYNCTCGTGNVGTTNSDMTINTC-LIEQCHVSVTDHKKWQFNSPFVPRADEP 581  Semliki Forest virus
Q8JUX5  496 MPPDTPDRTLLSQQSGNVKIT-VNGRTVRYKCNCGGSNEGLITTDKVINNC-KVDQCHAAVTNHKKWQYNSPLVPRNAEL 573  Chikungunya virus s...
7CVY_B  245 GdRKGKIRIPFPLANVTCMVPKARNPTVTYGKNQVIMLLYPDHPTLLSYRSMGEEPNYQEEWVTHKKEVVLTVPTEGLEV 324 
P03316  578 T-AQGKLHLPFKLIPSTCMVPVAHAPNVIHGFKHISLQLDTDHLTLLTTRRLGANPEPTTEWIVGKTVRNFTVDRDGLEY 656  Sindbis virus
P03315  582 A-RKGKVHIPFPLDNITCRVPMAREPTVIHGKREVTLHLHPDHPTLFSYRTLGEDPQYHEEWVTAAVERTIPVPVDGMEY 660  Semliki Forest virus
Q8JUX5  574 GdRKGKIHIPFPLANVTCMVPKARNPTVTYGKNQVIMLLYPDHPTLLSYRSMGEEPNYQEEWVTHKKEVVLTVPTEGLEV 653  Chikungunya virus s...
7CVY_B  325 TWGNNEPYKYWPQLSANGTAHGHPHEIILYYYELYPTMTVVVVSVASFILLSMVGMAVGMCMCARRRCITPYELTPGATV 404 
P03316  657 IWGNHEPVRVYAQESAPGDPHGWPHEIVQHYYHRHPVYTILAVASATVAMMIGVTVAVLCACKARRECLTPYALAPNAVI 736  Sindbis virus
P03315  661 HWGNNDPVRLWSQLTTEGKPHGWPHQIVQYYYGLYPAATVSAVVGMSLLALISIFASCYMLVAARSKCLTPYALTPGAAV 740  Semliki Forest virus
Q8JUX5  654 TWGNNEPYKYWPQLSANGTAHGHPHEIILYYYELYPTMTVVVVSVASFILLSMVGMAVGMCMCARRRCITPYELTPGATV 733  Chikungunya virus s...
7CVY_B  405 PFLLSLICC 413 
P03316  737 PTSLALLCC 745  Sindbis virus
P03315  741 PWTLGILCC 749  Semliki Forest virus
Q8JUX5  734 PFLLSLICC 742  Chikungunya virus strain S27-African prototype
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap