3P4E,2Z01


Conserved Protein Domain Family
PurM

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COG0150: PurM 
Phosphoribosylaminoimidazole (AIR) synthetase [Nucleotide transport and metabolism]
Phosphoribosylaminoimidazole (AIR) synthetase is part of the Pathway/BioSystem: Purine biosynthesis
Statistics
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PSSM-Id: 439920
Aligned: 682 rows
Threshold Bit Score: 253.81
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3P4E_A         7 NNPSLSYKDAGVDIDAGNALVERIKGAVKRTR--RPEVM-GGLGGFGALCELP------TKYKHPVLVSGTDGVGTKLRL 77 
AHB42790       1 mtELSRRPIQDVNIELGDDASKMLYEASKHTHanRPGLVrEAHESFSGFRSIPlsqfkdKDFENLEINLGFDGVGTKIEI 80 
WP_011720906   1 MTGPVSYATAGVDIDAGERAVELMRTAVARSS--RPEVL-GGLGGFAGLFRLDl-----TRYRRPVLATSTDGVGTKVAI 72 
WP_041255179  22 EGRSVSYRDAGVDVEAGDRAVQLMRQHVARAT--RPEVV-GSLGGFAGLFALDv-----ARYRHPLLASSTDGVGTKIAL 93 
WP_083769411  11 EEATVEYREAGVDIEAADSAVARIAQIVARTF--TERVA-SPIGGFGALYEIGg-----LGGARPTLVATTDGVGTKTEV 82 
WP_013021335   9 VATGASYREAGVDIEAGDKAVEGLKSKIRRAT--RPEVV-GGIGGFAGLFALDt-----QKYRKPLLASSTDGVGTKLVI 80 
WP_013133567   1 ---MTSYAEAGVDIAAGERAVELMKSRVARSR--RPEVI-DDPSGFAGLFDASa----fLRYRKPLLATSTDGVGTKVMI 70 
WP_013283426  33 RKRSVSYADAGVSIEAGDRAVELLKSKVKETR--RPEVM-GDLGGFAGLFRLDt-----KKYKNPILASSTDGVGTKLVI 104
WP_014378305   1 MSTEFTYAASGVDIDAGERAVTLMRAAVERTN--RPEVV-GGLGGFAGLFALDt-----AKYRRPLLASSTDGVGTKIAL 72 
WP_114593690   8 PTGGETYASAGVDLDAADDVVERIKPHVARTT--RPGVL-DTIGGFGGLFELDt-----ERYRKPVIVTATDGVGTKLAI 79 
3P4E_A        78 ALDMKKHDTIGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLD-----VDTAAEVISGIADGCLQAGCALIGGETAEMPGM 152
AHB42790      81 AERMDNHSTVAHDLFAMVCDDAVVRGAEPLAIGTILDVRQLDdtehtREALRQLAYGYVAAAGLAKVAVVNGEVAELGDR 160
WP_011720906  73 ARMLDRHDTIGLDLVAMVVDDIVVCGGEPLFLTDYIACGKIV-----PERIATIVAGIAEGCRIAGCALIGGETAEHPGL 147
WP_041255179  94 ARAMDVHDTVGIDLVAMVVDDLVVCGAEPLFLLDYIACGSLE-----PARIASIVAGIAAGCEQAGCALVGGETAEHPGL 168
WP_083769411  83 ARAGARYEGLGRDLVAMCVDDLVVTGATPLFFLDYLALGRVE-----PSLVALLVDAMAAALGEVGASLIGGEIAEHPGV 157
WP_013021335  81 AQRMGIHDTVGIDLVAMVVDDLVVCGAEPLFLLDYIACGKVV-----PERIADLGAGIADGCRYASCALIGGEIAEHPGV 155
WP_013133567  71 AQRLDKHDTIGIDLVGMVVDDLVVCGAEPLFMTDYIACGKVV-----PERIAEIVGGIAEGCRIAGCALIGGETAEHPGA 145
WP_013283426 105 AQQLDIHDTVGIDLVAMVVDDLVACGAEPLFLLDYIATGEVV-----PDKVAEIGAGIADGCRYAGCALLGGETAEHPGV 179
WP_014378305  73 ARQLDRHDTVGIDLVAMVVDDLVACGAEPLFLQDYVACGRVV-----PERIAAIVTGIAAGCTRAGAALVGGETAEHGDL 147
WP_114593690  80 ARQLGRHDTVGIDLVAMVVDDIVVSGAEPQVFLDYVAIGKLD-----PDVVTELVAGIAEGCVRAGCALVGGETAEHPGV 154
3P4E_A       153 YEG---EDYDVAGFCVGVVEKEEIIDGSKVQVGDALIAVGSSGPHSNGYSLVRKIL-Ev-----------SK-ADKNERL 216
AHB42790     161 VGGfgeFNYNWGAAILWVAHKDRILTGHQIEAGNTLVGFSEHGFRSNGITDVRKAMlKe-----------YG-EDWHNKI 228
WP_011720906 148 LEP---DEYDLAGAATGVVEEDALLGPHRVTAGDAVVAMASSGLHANGYSLVRHIFfTl-----------AG-WRLDRYV 212
WP_041255179 169 MGI---DDYDLAATGVGVVEADAVLGPELVRPGDVVVAMGSSGLHSNGFSLVRHILfGpvepdqpggvsvAGrEALSRHE 245
WP_083769411 158 LEP---GQVDLAGFCVGIVDGDATLGSERVRAGDRVLGLRSPNLRSNGFSLVRRVYaDv----------lEA-VA-RGET 222
WP_013021335 156 LGA---DEYDVSATGVGAVEADAVLGPEKVAAGDVVIGMAASGLHSNGFSLVRHVLlGe-----------DG-MSLDTVV 220
WP_013133567 146 MKP---DEYDLAGAGTGVVEASELLGPHRVVPGDVVLGMASSGIHSNGYSLVRHII-At-----------AG-LRLDQEL 209
WP_013283426 180 LRP---DEYDISATGVGVVEESEILSPERVEVGDVVIAMRSSGLHSNGYSLVRHVLlGa-----------GR-MRLDVVI 244
WP_014378305 148 MDA---DEYDLAATAVGVVEADAVLGPERVHEGDAVIAMASSGFHSNGYSLVRRVV-Ga-----------AG-LDLHATP 211
WP_114593690 155 MPA---TDYDLAGFAVGMVEKDAILGPHRVSDGDVLIGMAASGLHSNGYSLARRLV-E-------------G-LDLSEH- 215
3P4E_A       217 A-----G--KTIGEHLLAPTKIYIKSGLKLI------AE---HDIHAISHITGGGFWENIPRVL-PEGTKAVIDGKSWEW 279
AHB42790     229 Drs-lsD--VALGKLVQAPSIIYSGFMSELTggydiaKEs-lARVTGVAHITGGGQPSKIGRMLePSGLGVEISNP-NTP 303
WP_011720906 213 Pe---lG--RSLGDELLTPTTIYAPHCLRLR------EA---VDVHAFAHITGGGLAGNVARVI-PEEYTAVIDRSTWQP 277
WP_041255179 246 Ea---lG--TTLGQALLTPTRIYARDCLAVI------ET---AEVHAFAHITGGGLAANLARVI-PPGTAAVVERSTWAP 310
WP_083769411 223 GplladG--RPLYDALIEPSVLYAPLVLEFA------RA---GLLHAAAHVTGGGLAGNLVRVL-PTGLGVEVK--PWAW 288
WP_013021335 221 Pe---fGnqRTLGEELLTPTKIYARDCLAII------EE---CEVHAFSHITGGGVPGNLVRSI-PSTVDAVVDRGSWRP 287
WP_013133567 210 Pe---lS--RTLGEELLEPTRIYAPHCLALT------RE---VDVHAFAHITGGGLAANLARSL-PATADALLDRGSWTP 274
WP_013283426 245 Dd---fGrqRTLGEELLTPTKIYAQDCLKLI------AE---AEVRALAHVTGGGIPGNLVRVL-PEHVDAVVNRSTWKP 311
WP_014378305 212 Ag---lD--RALGEELLEPTRIYALDCLALV------EVlgvEGVHAYAHITGGGLAGNTARVV-PDGLQAVLDRSTWAL 279
WP_114593690 216 Hg---lD--RPLGDALLEPTAIYTKPCLALA------EA---GLVNALCHVTGGGLPGNLPRVL-PESLGADVDTSSWTP 280
3P4E_A       280 PVIFQWLQEKGNVTTHEMYRTFNCGVGLIIALPKDQANAAVALLQAEGETAWVIGEIAAAnsNEa---Q-V-EI 348
AHB42790     304 PDIMLKMQEIRGFDDRTAYGKWHMGPGMVVAT--NEPEKVLEAAEQHGVVAQEIGVVTEK--PG------I-KI 366
WP_011720906 278 PSIFRLVGELGRVPQAELERALNMGIGMVAIVASPDADRAVELLNATGIRAWVAGHVQPR--ADdaaaH----L 345
WP_041255179 311 QAVFGLLAERGGVSEADMEATFNQGVGMVAVVAPAEAEAVVRTLADRGVAAWIAGRVEPL--PGgageDgVaRL 382
WP_083769411 289 PEIFRRLADDGDVSLEAMRATFNLGIGMVLIAPPDAASALRERV----PDAVDLGVVEAS--De----G-V-TW 350
WP_013021335 288 QPVFDLVARSGGIAAEEMERTFNMGMGMAAIVPADQVDRTMALLTARGTDSWVAGRIEPG--RGe-----V-KL 353
WP_013133567 275 PAIFQVLAGYGKVPQAEMDRTFNLGVGMCAIVPADQADRAVELLNGQGVPTWVLGEVVPG--Sg-----eA-Rf 340
WP_013283426 312 QPIFDLIQSKGRIEDPEMEATFNMGVGMFAIVSAEDADRALATLTGRGVDAWQAGEIIEG--SG----N-V-QM 377
WP_014378305 280 PVAVRLMEEHG-VPRAESERAFNCGVGMIAAVAPDRADAAVALLTARGVPAWIAGTVRER--SDgdapA-A-EL 348
WP_114593690 281 GPLFELMGRLGQVEREEMFRVFNMGVGMVAVVPEHAVEAAVGLLSEHDVEAWVMGRVTGP--AG------V-RL 345
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