Conserved Protein Domain Family
HU_rel
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TIGR01201: HU_rel 
DNA-binding protein, histone-like, putative
This model describes a set of proteins related to but longer than DNA-binding protein HU. Its distinctive domain architecture compared to HU and related histone-like DNA-binding proteins justifies the designation as superfamily. Members include, so far, one from Bacteroides fragilis, a gut bacterium, and ten from Porphyromonas gingivalis, an oral anaerobe. [DNA metabolism, Chromosome-associated proteins]
Links
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Statistics
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PSSM-Id: 273496
Aligned: 9 rows
Threshold Bit Score: 144.811
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAG26483       1 MPlFYRARQSQLKTKE--G-KKQWHLTLVKVG-KMvTSQQLAEVIAEKSSLTPGDVHNVIRNLMTAMRKELLNSRSVRLE 76  Bacteroides fra...
WP_021662703   1 ML-FFKRRQSCIAHKAt-G-KKLWYPQTVING-STaSTLHIAEQISELSGASPGDVFGILRDLGIVMRRELASGKKIKLD 76  Porphyromonas g...
WP_018965541   1 MI-QYTVKERRMKVGKhaG-KTMYYAEAQKSK-VI-DFEEVIRDVAEMSSLTTGDVRNAVDRLAYYLRRELAEGNTVRLG 76  Porphyromonas g...
WP_005874045   1 MI-KIKAIERKAGFGKt-S-KTLWYPAIHLHS-DV-KFEEFIELVSDETTVSSADIKAVFDRAAKVLIRLLQDGKSIDCG 75  Porphyromonas g...
WP_005874254   1 ML-NLSVKSRLMKIGKh-KdKTMYYAQVDKPR-VI-EYEDVIKDIAEMSSLTTGDVRNAIDRLAYYLQRELTEGNTVRLG 76  Porphyromonas g...
WP_012458253   1 MI-GYVSKQSKVANKD--G-KRVWYPQTVASGrVI-DTKRVARELAARSGASEGDVHGILHDLGLVLRDYLSTGARVVLD 75  Porphyromonas g...
WP_004583683   1 mavSFKVKERKVMINGq-P-AKIRYAQTLKTG-DM-DLSEICDLTSKISAVSEGDVRSIINTVTGLVITGLKQGRAISLG 76  Porphyromonas g...
WP_005874172   2 sL-KYVIKKSVAKIGPkaG-QTIYYAQPAAQD-SV-TFHSLCKRIAEESALTSADVKGILDRLVNILSEELPNGKTVRIG 77  Porphyromonas g...
WP_004583626   1 MA-KFVMREMPDMQGTg-K-RTM-YPKMISRG-TM-GLDEIADLISSQSTFSPGEVKGLVTALARTIAHGVASGYTVKIE 74  Porphyromonas g...

AAG26483      77 GLGTFTMKACT-Q-GHGVDQEE---EVSPNQVAALRCLFTPEYTR--------------------PAAIGTTRALLQG-- 129 Bacteroides fra...
WP_021662703  77 GIGCFRLIAQA-K-GSGVEKKE---DVKASQFNSVRVNFRAECRY--------------------NTVTRERDCTLIA-- 129 Porphyromonas g...
WP_018965541  77 QIGTFRLYAPG-R---FMEHPE---DVNATTIKGAKIQFIQNRHL--------------------REASSSIRIAVDN-- 127 Porphyromonas g...
WP_005874045  76 DMGTYRPSITA-KaGSGVDSAD---KVTVELVDKAKVIYTPRMKV--------------------KTALKGVRMERAE-- 129 Porphyromonas g...
WP_005874254  77 QIGTFRVSVPS-K---YVETEK---EVNASILKKPRIRFYINNTL--------------------SAVADNIRLAVY--- 126 Porphyromonas g...
WP_012458253  76 GVGSFRITANA-R-GKGVEKKE---DVSPRQFNSIRVAFYPEKRV--------------------NQSTHTTNVTLIDpn 130 Porphyromonas g...
WP_004583683  77 ELGRFRISLSS-K-A--AKEGE---EFTVENIRRARVLFLPGGDI--------------------RRACRQIRLKGIN-- 127 Porphyromonas g...
WP_005874172  78 ELGSFRLSFGS-K---QLDDPK---NFSVDQIQKHRLVFIPSAEL--------------------KSIPARGKLRPGSsa 130 Porphyromonas g...
WP_004583626  75 EIGSFSASLTLhK-GVEPEEAEggtRRNAASVTIGGVNFRPDKALileartrvhlvrttvrrprrPNLTREERLALAL-- 151 Porphyromonas g...

AAG26483     130 ---V------EFQKVSAI-------G-------GAIN 143 Bacteroides fragilis
WP_021662703 130 ---Pdlk-faEYGKPLPA-------G-------ASAN 148 Porphyromonas gingivalis
WP_018965541 128 ---P------YLTKKKDlttggtesaegdasagl--- 152 Porphyromonas gulae
WP_005874045 130 ---R------VLDVPYAS-------S-------IKPn 143 Porphyromonas gingivalis
WP_005874254 127 ---R------NGQKVDDT-------T--------SPS 139 Porphyromonas gingivalis
WP_012458253 131 lrfV------YVKNPKDAagnassqT-------NTPD 154 Porphyromonas gingivalis
WP_004583683 128 ----------MLRPGEQQ-------G-------GTPS 140 Porphyromonas gingivalis
WP_005874172 131 lafD------YERVEPQP-------KkkpgtgdNQTP 154 Porphyromonas gingivalis
WP_004583626 152 ---RhldghsLLKVADYCrltglgrT-------AAAE 178 Porphyromonas gingivalis
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