Conserved Protein Domain Family
bHLH_AtNAI1_like

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cd11452: bHLH_AtNAI1_like 
basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana protein NAI1 and similar proteins
NAI1, also termed AtbHLH20, or EN 27, is a bHLH transcription activator that regulates the expression of at least NAI2, PYK10 and PBP1. It is required for and mediates the formation of endoplasmic reticulum bodies (ER bodies). It plays a role in the symbiotic interactions with the endophytes of the Sebacinaceae fungus family, such as Piriformospora indica and Sebacina.
Statistics
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PSSM-Id: 381458
Aligned: 7 rows
Threshold Bit Score: 116.024
Created: 10-Jun-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative DNAputative dimer
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:The N-terminal basic region of bHLH mediates high-affinity DNA-binding to specific hexanucleotide sequences
  • Comment:Based on the structure evidence that Arabidopsis thaliana MYC2 (5GNJ) binds DNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1             ##  ## ##   #                ##                                       
Q8S3F1       128 HLLKEHVLAERKRRQKLNERLIALSALLPGLKKTDKATVLEDAIKHLKQLQERVKKLEEERVVTKKMDQSIILVK 202 thale cress
Q9T072       148 SNAQDHIIAERKRREKLTQRFVALSALVPGLKKMDKASVLGDALKHIKYLQERVGELEEQKKERRLESMVLVKKS 222 thale cress
Q1PF17       122 SNAQDHILAERKRREKLTQRFVALSALIPGLKKMDKASVLGDAIKHIKYLQESVKEYEEQKKEKTMESVVLVKKS 196 thale cress
Q1PF16       115 VLAKEHVLAERKRREKLSEKFIALSALLPGLKKADKVTILDDAISRMKQLQEQLRTLKEEKEATRQMESMILVKK 189 thale cress
PNR50930     227 GHTQDHIMAERKRREKLSQRFIALSAIVPGLKKMDKASVLGDAIKYVKTLEEKLKTMEERLPKKRIRSLSNKKSS 301 Physcomitrella patens
XP_019577843 151 SNSQDHIIAERKRREKLTQRFVALSALVPGLKKMDKASVLGDALKHIKYLQERVGEFEEQKRERRLESMVLVLKK 225 Chinese rufous horse...
EFJ10798       9 GHTLDHIMAERKRREKLSQRFIALSAIVPGLKKMDKASVLGDAIKYVKQLQERLKSLEEHVSRKGVQSVAYCKKS 83  Selaginella moellend...

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