2PE4


Conserved Protein Domain Family
Glyco_hydro_56

?
pfam01630: Glyco_hydro_56 
Hyaluronidase
Statistics
?
PSSM-Id: 460272
Aligned: 113 rows
Threshold Bit Score: 210.442
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2PE4_A          6 PLLPNRPFTTVWNANTQWCLERHGVDVD-VS-VFDVVANPGQTFRGPDMTIFYSSQLGTYPYYTPtG----Ep---VFGG 76   human
EKC31491       21 RSETRQAFVATWNVPSEVCSQKFNIEFD-LK-QFRIDSNKNTSFMGEEVVLFYEPLPGLYPKYLSnG----Sa---LNGG 91  
EEB14203       20 AYPTLEEFKIYWNVPTFLCH-KYGINFKpHTeKYGITSNPKDSFRGKEINILYDP--GMFPAVMKnAkg-vVa--eRNGG 93  
EEB14205      217 IPGSHRGFKIYWNVPSDRCK-KHNIHFEpLTkMYGIIANKNDSFRGENVSILYDP--GEFPIIQKfPnn-tVk--yHNGG 290 
EEB14204       33 PPESNRGFKVFWNVPTEQCK-KYEIDFEsLIrTYGIIGNERDSFRGEKVTILYDP--GDFPIIKKfQnk-tQr--yYNGG 106 
18_pfamImport   1 AGTERRRFPVYWNVPTFQCH-KYGLNFTrVAkAWGIEQNLGDEFRGEEISILYDP--GEFPALLTaAtt-eAv--pRNGG 74  
XP_001944830   77 NDVQSDEFRVYWNVPTFQCH-KYGYKFDeVA-EWGIQQNVDDNFRGDKISLLYDP--GLFPALMQgGgs-rAdhviRNGG 151 
XP_015836381   32 KLTKVQKVNYYWNVPTFQCD-SHKLNFTgLAdKFGIIQNENDRFRGNEVAILYDP--GSFPALLRdGs--gIv--rRNGG 104 
OWR47683       31 VKEFKKEFRVYWNVPTFQCA-SKKIPFDkLYeKFGIIQNNGDRFNGEKITILYEL--GDFPSIFKnKtsgeYe--fINNG 105 
EFN78468       21 REGNPHKFDVYWNVPTFMCH-KYGMKFEnLN-DYGIQQNAMDKFRGDKIVILYDP--GMFPALLVsKng-tVt--kRNGG 93  
2PE4_A         77 LPQNASLIAHLARTFQDIl-AAIPaPDFSGLAVIDWEAWRPRWAFN-WD-TKDIYRQRSRAL--VQAQHPDWPAPQVEAV 151  human
EKC31491       92 IPQRVPFDHHFQKVANDId-VLVPaKDFLGKGVIDWESWRPIFERNtYEpDKLIYINESKKL--AKSLYPAWNSTMIGKM 168 
EEB14203       94 IPQLGNITLHLEAFKNVV--EQIVsPDLHGIGIIDFETWRPVFRQN-WR-DQVVYKNLSKDL--ERQYHPQWSEKKIREK 167 
EEB14205      291 FPQNGSLEKHLEKLKADI--EKFVyKNFSGLGIIDFEVWRPVFRQN-WN-DQVIYRNKSFEWakELKNNCSIAEGKINAT 366 
EEB14204      107 FPQNGSLSKHLKKLKNDT--RKYAnVNLNGLGIIDFEVWRPVFRQN-WN-EQIIYKNKSIELaqHLKNNGSLNGKSVNAS 182 
18_pfamImport  75 VPQEGSLMHHLKLFQMHM--EKLVlPGFKGLGVIDFEHWRPVWHQN-WG-SLNTYREYSRII--ERKRHPFWFSSMIEIE 148 
XP_001944830  152 VPHEGNLTKHLELFTRDLvtKLVPdPSFSGLAIIDFEHWRPMYEEN-FG-SLSLYKDYSMEI--EKYNHPYWQKEDLQKE 227 
XP_015836381  105 VPQEGNLTLHLALFEELLn-ELLP-EDFSGLGIIDFESWRPIYRQN-FG-SLAPYKDLSVEI--ERQSHPFWPKLLLEKE 178 
OWR47683      106 VPQEGNLQEHLVAFKEQLl-EKIPdPFFDGVGVIDFEMWRPVFDQN-FG-NLDVYRKRSIEI--EKERHSWWLNMWIKKE 180 
EFN78468       94 VPQEGDLKEHLEKFREDLv-TQIPhESFSGVAVIDFESWRPIFRQN-WA-SLEPYKTLSIKL--ERERHPFWSDAAVKKE 168 
2PE4_A        152 AQDQFQGAARAWMAGTLQLGRALRPRGLWGFYGFPDCYN-YDFLSPnYTGQ---CPSGIRAQNDQLGWLWGQSRALYPSI 227  human
EKC31491      169 AEIMFEESARKLMEKTLMIARDLRPRGSWGFYGFPRCFN--------YEKDedkCSKETMKFNDQLSWLFQASKSLYPSI 240 
EEB14203      168 AKIHFEEASKEFMEKTLELAKILRPKAIWGYYGFPYCYNyRTTDEPe-------CPELARRENDKILWLFNTSTAFYPSL 240 
EEB14205      367 AKETFEAHAKKFMLETLKEVKKLRPEGKWGYYGFPYCYNyRVNDTPe-------CPKIAVKENNETLWLFNESTALYPSI 439 
EEB14204      183 AKEEFEKHAKKFMLETLEDVKKLRPGGKWGYYGFPYCYNyRVNNTPe-------CPEIAVRENNEILWLFNESSALYPSL 255 
18_pfamImport 149 AVYRYELSAKTFILETLRKAKQLRPKALWGYYGYPFCFNfTPNNNRe------aCSDEVVVDNNNMQWLFSESTAHYPSL 222 
XP_001944830  228 ASRKFEKAAIQFLKRTLQVAKSLRPNAYWGYYGYPFCFNyTPKNDQa------kCSSNVMKNNEKSKWLFEESTAIFPSL 301 
XP_015836381  179 ARRRFEFHARRFMEETLFVAKSLRKNATWGYYAYPYCFNmSPNNMKk------dCPNEVQKENDQLDWLFRLSDDLHPSI 252 
OWR47683      181 AAIRFETAARKFMESTLVLAKQMRPNALWGYYGYPHCFNmRDMDMKe------dCVKSIPGANDNIYWLWAESTALFPSI 254 
EFN78468      169 AKRRFEKFGRMFMEESLKMAKKLRPWAMWGYYGYPHCFNkSPGQQSm------hCDRSTMTENDEMSWLFMLEDVHAPSV 242 
2PE4_A        228 YMP-AVLEGTGKSQMYVQHRVAEAFRVAV---AAGDP--NLP-VLPYVQIFYDtT--NHFLPLDELEHSLGESAAQGAAG 298  human
EKC31491      241 YLS-SKFPSPSSRQKRVQGILNETLRVHSrfsTSNTR------MHAYSTYRY--TdnDMFYSQEDLINSIGQSFDAGMDG 311 
EEB14203      241 YMS-TKLNEF-QQSQFVIGRLNEAWRMA-----IKVSgpKIPrVNPYIWFKYY-Ds-eEFLSYADIYSALDVTRKYKMGG 311 
EEB14205      440 YIK-TKYNET-EHVKFMIGKLNEAYRVS-----AMAN--YVP-VYPYVWFRYL-Dn-dTYLTEADMFYSIDIPRHYQMGG 507 
EEB14204      256 YLK-QSYNSS-EHVKFMIGVLNEAYRIS-----AMTN--YIP-VYPYVRFKYL-Dt-dEYLTQEDAYNSFEIPRQYQMGG 323 
18_pfamImport 223 YLKeRDMGPA-KRRRFVRGRLVEALRVAN----------NTP-VYPYVWYKYH-Dt-nQFLTEDDMYHVLKAPRDRGCTG 288 
XP_001944830  302 YFKyENMSSE-KRSRFMQGRMAEAMRVGNmgnTKKI-------VYPYTWIKYY-Dt-kQFVEKADLMNSFSIPKKNDASG 371 
XP_015836381  253 YLD-GRLGPK-DKIRMIEGRINEAHRVAA---FVKSGalKPK-IVPYFWYKYH-Gg-qNFLTKEDLFNAILTLSTSDIDG 324 
OWR47683      255 YSS-KKLTNS-QLPFHIKGRIKESARVRLe---------DTP-ILPYFWFRYR-Da--EFFSQEDLSIALNTLYQSKASG 319 
EFN78468      243 YLR-LEIKEG-DRPGFVKGRVSEAQRLA------VKSlrKQQ-ILPYYWFKYQ-DnrDKLLSEKDTMNTIEMIANHGADG 312 
2PE4_A        299 VVLWVSWENTRTKESCQAIKEYMDTTLGPFILNVTSGA 336  human
EKC31491      312 VILWDSSKNFKSRADCQNVKDYLQFSLGPLVKKVIDFA 349 
EEB14203      312 AIIWGSSNNVNSKEKCKTLLRYLDTVLGPAARKTLQNQ 349 
EEB14205      508 IILWGKGSDLDSKDKCQKFFQYMNETLGPALNRSLSYG 545 
EEB14204      324 IILWGKSSDLNDEGKCLKFYNYVIDIVGPALNKSLTMG 361 
18_pfamImport 289 VVIWGASKDVNTEAKCLALASYLENVIGPAVSYV-NSL 325 
XP_001944830  372 VIIWGASNDVNSEKKCKAMHNYLTGVLGPTLKAFYKSN 409 
XP_015836381  325 VVIWGSSNDVNTKNKCLDLYEYVDNVLGPSLVN----F 358 
OWR47683      320 VIIWGSSNDVNTVDKCKKLYNYVETILGPNIAKYTQRS 357 
EFN78468      313 AIIWGSSNDVNTQRKCEDLLQYMKDVLGPTKEELKGNP 350 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap