Conserved Protein Domain Family
FAM176

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pfam14851: FAM176 
FAM176 family
Members of the FAM176 family regulate autophagy and apoptosis.
Statistics
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PSSM-Id: 464347
Aligned: 25 rows
Threshold Bit Score: 137.049
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003227426   7 EMELLSNSIAAYAHIRDHPESFGLYFVLGVCFGLVLTLCLLVIHISWQPQALp---PRPRKKRLRDLSEEEe-------- 75 
XP_014342488 288 DGLIVSNSLAAYAYINGHPERAGLLFISSVCIGLVLTLCILVIRVSCRADFQr---LHEKKGHHVWDSD----------- 353
XP_001377554 297 DGVIVSNSLATFAYIRAHSERAALLFVSSVCIGLIVTLFAVVIRVSCTKDFQk---LSQGKKRLVPEAEKTen------- 366
XP_026369029 301 DGVIVSNSLAAFAYIRAHPERAALLFVSSVCIGLALTLCALVIRVSCTKDFRe---LQLAREHLVPESDKA--------- 368
XP_008105806 355 DGIIVSNSLATFAYIRDHPERAALLFVSSVCVGLVLTLCALVVHVSCSNDLEn---LRRIKKHLAPED-KAdengk---- 426
XP_016160653 160 GTIVSSNYLATFAYIRDHPERAALLFVSSVCVGLILTLCALVICVSCPRDIQk---LHKKRDELLPESARAyq------- 229
XP_014968040  13 EMALLSNILAAYSFVSENPERAALYFVSGVCIGLVLTLAALVIRISCHTDCRr---RPKKKFLQDRESSSD--------- 80 
XP_014328804  19 EMAMLSNLLAAYTFIADQPERTALVFLGGVCVGLLVTLCAIVFQIHCRADCHygnsNDLQKRQRVRRHRRQhlcarpqlt 98 
XP_021324380   1 -MSLISSLLAAYTYITEHPERCALYFMCGVCAGLFLTLFALVVQISCRMDCKpr-hGAAKKRPRAVDSDSD--------- 69 
Q08CB3        15 EMALVSNALAAYSFIADQPERAALYFVCGVCLGLVLTLIALVVQISCRTDCKt--qQAPKKTGKTVENTSD--------- 83  zebrafish
XP_003227426  76 ------------------eEDDEE-EEDEEEEEDAVDAESSEPVlaltelpsetqaTPPDGT--TVNVFASAEELERAQR 134
XP_014342488 354 -------------------DEDAD-SDSDGKDDEPSDSDFCSEI------------TGFYRT--SQSVYDNAEAAELAER 399
XP_001377554 367 ------------------dSEDGE-EE------DSSDSDFPDEM------------TEFFRT--SYPVYSSTEAAEMAER 407
XP_026369029 369 -------------------EEDSE-DE--EGAEDSSDSDFPGEL------------SGFCRT--SYPVYSSIEAAELAER 412
XP_008105806 427 --------------eeeeeEEEEE-EEDEEERDDSSDSDFPD---------------GFCRT--PYSAFYSIDSAELAER 474
XP_016160653 230 ------------------tSEQEE-EEE-----DSSLSNSQDET------------DRLYRP--SYSGYNSAEAAELAER 271
XP_014968040  81 -------------------SSDSEdGSEDTASDLSVRRH-----------------RRFERTl-NKNVFTSAEELERAQR 123
XP_014328804  99 dgnpdntgavvvasgvtgnTGDCEpEDWDDTSDLSARRR-----------------RRFERAllNATMFTSSEELDRAQR 161
XP_021324380  70 -------------------TTDSD-SDWDTGSDLSARRH-----------------RRFERTl-NTNVFTSAEELERAQR 111
Q08CB3        84 -------------------TSDSD-SDWDNTSDLSARRH-----------------RRFERTl--GNVFTSAEELERAQR 124 zebrafish
XP_003227426 135 LEERERILREIWRNGQPDIlGSGTGTLGRVH 165
XP_014342488 400 LEHREQIIQEIWMNGGLDM--STIRTFNQ-- 426
XP_001377554 408 IERRDQIIQEIWMNSGLDT--SSPRNLDQYY 436
XP_026369029 413 IERREQIIQEIWMNSGLDT--SLPRNMGQFY 441
XP_008105806 475 IERREQIIQEIWMNSGLDA--SPTRSLSPFY 503
XP_016160653 272 IERREQIIQEIWMNSGLDM--TPPRNMNTFY 300
XP_014968040 124 LEERERIIREIWMNGQPEV--PGTRSLNRYY 152
XP_014328804 162 LEERERVLREIWMNGQPDI-STVTQSLNRYY 191
XP_021324380 112 LEERERIIREIWMNGQPDV--PGTRSLNRYY 140
Q08CB3       125 LEERERIIREIWMNGQPDM--PGTRSLNRYY 153 zebrafish
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