Conserved Protein Domain Family
PDH_E1_alph_x

?
TIGR03181: PDH_E1_alph_x 
pyruvate dehydrogenase E1 component, alpha subunit
Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase]
Statistics
?
PSSM-Id: 213783
Aligned: 44 rows
Threshold Bit Score: 428.101
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_011187094  12 NTVQLLTSDGRfqpsepaGE---YLPYLERLDENDYRRFYRDMVRVRAFDHEAANLQRQGQLGLWVPSHGQEGAQVGSAY 88  Leifsonia xyli
WP_011237053  10 DYTRFLDPRGE-------AT---QPLPDFALDPEKLIPLYRAMVLTRTFDTKAIALQRTGKLGTFASALGQEAIGVGVAA 79  Aromatoleum aro...
WP_011001735  10 DYTQYLDPEGQ-------PV---QPLPAFAQDVPTLLALYRAMVLTRAFDTKAIALQRTGKLGTFASSVGQEAIGVGVAS 79  Ralstonia solan...
WP_011301090  10 gYTRYLDPPGA-------TPvssSPLPPFANDPDALLPLYRAMVLTRQFDLKAIAMQRTGKIGTFASALGQEAVGVGVAS 82  Cupriavidus pin...
WP_002809958  10 hYTQCLNENAE-------VI---GVLPSFAHDPQNLIPLYRTMTLTRLFDKKAVSLQRTGQLGTYASSLGQEAISVAIGH 79  Nitrosococcus o...
WP_012570222  14 rYLQFLDANSN-------PT---QPFPDFA-DPDMLLYLYRRMALIRQLDNKAINLQRTGKMGTYPSSRGQEAVGIGMGS 82  Coxiella burnetii
WP_011081422   7 PMHRFLDYEGN-------VQ---SPLPSWA-SEERLVQFYRDMLITRAYDNKAVALQRTGKLGTYPSHLGSEAFGVGIGH 75  Vibrio vulnificus
WP_031804706   9 PFTRYLDSDGR-------PL---GELPAWAGDSDALVGLYRQMLLTRLFDQKAVALQRTGRIGTYAPTLGQEAIGVAIGS 78  Pseudomonas aer...
WP_004514777  12 krleIIAPDGT-------A----DEDLVPGLSGDELRRIYYLLLLTRAYDGRALALQREGRLGTYPSVLGQEAAQVGSAF 80  Geobacter metal...
WP_003486391  10 DYLQYMDADGQw------VR---DDLPADAANPQHLLALFKRMLFVRTFDTKSVALQRTGKLGTYAACIGHEATHVGIGA 80  Xanthomonas
WP_011187094  89 AARPQDNIFPSYREHVIGMIRGIDPVGIMGLLRGVTHGGWD--PTDpavEN----FHLYTLVIGSHTLHATGYAMGVKFD 162 Leifsonia xyli
WP_011237053  80 AMRAEDVLVPSYRDHPAQLLRGVTMAESLLYWGGDERGSDF--AGP---RD----DFPICVPIATQVCHAAGAAYAFQLR 150 Aromatoleum aro...
WP_011001735  80 AMRAEDVLFPSYRDHSAQLLRGVSMAESLLYWGGDERGSCF--AAV---RE----DFPNCVPIGTQVCHAAGAAYAFQLR 150 Ralstonia solan...
WP_011301090  83 AMRPEDILVPSYRDHAAQFVRGVTMTESLLYWGGDERGSGF--AAA---PH----DFGNNVPIGTQVCHAAGVAYAVQLR 153 Cupriavidus pin...
WP_002809958  80 VMSADDVLLTTYREYGAQLQRGVTMTELLLYWGGDERGMAY--QDC---RH----DFPISVPVASQVPHAVGVAYAMKLR 150 Nitrosococcus o...
WP_012570222  83 AMQKEDIFCPYYRDQGALFEHGIKLSEILAYWGGDERGSRYanPDV---KD----DFPNCVPIAGQLLHAAGVAYAVKYR 155 Coxiella burnetii
WP_011081422  76 ALKPSDVFIPYYRDMPAMWVRGIGMEKNLQYWGGDERGSDFc-PEE---SHlrcsDLPFCVPIATQCTHAVGVASALKIQ 151 Vibrio vulnificus
WP_031804706  79 QMRAEDVLVPYYRDTAVQLMRGVRMEDILLYWGGDERGSDYaePLA---AQ----DFPICVPIATQALHACGVASAFRIR 151 Pseudomonas aer...
WP_004514777  81 AIHERDWVFPSFREMGVHLTLGYPAHQLFQYWGGDERGMRT--PDG---MN----IFPISVSVGTHIPHAAGAALAAKLR 151 Geobacter metal...
WP_003486391  81 SMRSGDVFAPSYREYGTMFERGVRPRDVLLYWGGDERGSDY--PRD---ADaa-iDFPICVPISTQCLHAAGSALSFKLQ 154 Xanthomonas
WP_011187094 163 GKvgtgnpeaDEAVICYFGDGATSQGDVSEALVFAASYQTPQVFFLQNNQWAISVPVKTQSRTP-LYLRSSGFGIPGVQI 241 Leifsonia xyli
WP_011237053 151 QE--------ARVAVCFIGDGGTSKGDFYEALNFGAVWKAPLVVVVNNNQWAISVPRSMQSAAQtLAQKAIAAGIEGCQV 222 Aromatoleum aro...
WP_011001735 151 RE--------PRVAVAVFGDGGTSKGDFYEGMNLAGVWGAPLVLIVNNNQWAISVPRSRQTAAQtLAQKAIAAGIAGRQV 222 Ralstonia solan...
WP_011301090 154 GE--------PRVAVCMLGDGGTSKGDFYEGMNMAGAWHAPLVIVVNNNQWAISMPRSRQTAAHtLAQKAIAAGIPGEQI 225 Cupriavidus pin...
WP_002809958 151 RE--------PRVAVCVLGDGATSKGDFYEAMNAAGLWRLPVVFVINNNGWAISVPLAAQTRTQtLAQKAIAAGIPGEQV 222 Nitrosococcus o...
WP_012570222 156 KQ--------ARAVLTICGDGGTSKGDFYEAINLAGCWQLPLVFIINNNQWAISVARGEQTHCQtLAQKAIAGGFEGWQV 227 Coxiella burnetii
WP_011081422 152 GN--------HDAALVTCGDGATSKGDFLESINCAGVWHLPLVFVVNNNQWAISVPRQLQCAADlLSEKAKGAGIPGITV 223 Vibrio vulnificus
WP_031804706 152 GE--------HRVAVTTCGDGATSKGDFLEALNVAGAWQLPVLFVVNNNQWAISVPRRIQCGAPtLAEKAVGAGFPGEQV 223 Pseudomonas aer...
WP_004514777 152 GD--------PIAVIAYFGDGGTSKGDFHEGFNLAGVMGLPTVFICQNNQWAISVPLSAQTASRsLAQKALAYGFDGIQV 223 Geobacter metal...
WP_003486391 155 GK--------QHVAVACCGDGGSSKTDFYAALNSAGAYKLPLILCVINNGWAISVPRSAQTGAQtLAQKGLAGGLHCLQV 226 Xanthomonas
WP_011187094 242 DGNDVLAAYAVTAKHLDDARGGEGPSMIEALTYRMGAHTSSDDPTKYRTDDEVR-HWAERDPILRFRAFLEQQGL-GQTF 319 Leifsonia xyli
WP_011237053 223 DGNDIVAVHHAARQAIEKARSGGGPSLIEALSYRLGDHTTADDASRYRDPAVVQ-ENWTFEPVVRLRNHLVRLNAwDPQH 301 Aromatoleum aro...
WP_011001735 223 DGNDVIAVRQAAQDALDKARSGGGPTLIEALSYRLGDHTTADDATRYRDPDSVK-QAWAREPILRLRNYLMRLSAwDKAQ 301 Ralstonia solan...
WP_011301090 226 DGNDVVAVRHRVGEAIERARAGEGPSLIEAITYRLGDHTTADDASRYRDESTVK-AHWQAEPLLRLREHLVKLGAwDAGR 304 Cupriavidus pin...
WP_002809958 223 DGNDVIALRTRMENAIEKARRGEGPCLIEALTYRLCDHTTADDASRYREQAEVE-ARWRLDPIQRLRTYLTQAGAwDEEQ 301 Nitrosococcus o...
WP_012570222 228 DGNDVIAVRYAVSKALEKARDGGGPTLIEALSYRLCDHTTADDATRYIPQEEWKvAWQ-KEPIARLGYYLESQGLwSREK 306 Coxiella burnetii
WP_011081422 224 DGNDVVAVYDAVNNALDRARKGKGATLIEAISYRLSDHTTADDASRYRSADELK-QAWQYEPIKRLQAYLTAQGLwNEEL 302 Vibrio vulnificus
WP_031804706 224 DGNDVLAVAERVRAALERARQGKGPTLLECISYRLCDHTTADDASRYRSAEEVN-QAWREEPIKRLRAFLAGRGQwDEER 302 Pseudomonas aer...
WP_004514777 224 DGNDVLAVYRATREALEKARSGGGPTFIECLTYRMSDHTTSDDASRYRSPEEME-QWRERDPILRYERFLAKRGLwNEDY 302 Geobacter metal...
WP_003486391 227 DGNDLVAVLEAMRQARVRALAGEGGTVIEFLTYRLSDHTTADDARRYRGEEEVK-QGWAREPLLRLRRYLTAQGLwDEAQ 305 Xanthomonas
WP_011187094 320 FDSADEEAADLAADVRRRTLELTPPPADSMFEHVYSEPHPVMEEQRRWL 368 Leifsonia xyli
WP_011237053 302 EEQLVRECGEAVNAAVERYLATPPPTPEAMFDHLYRTLPAALQEQRDMA 350 Aromatoleum aromaticum
WP_011001735 302 EEQLGRACYAQVEEAVAAYLAVGQPGPSAMFDHLYAALPRALEAQRAMA 350 Ralstonia solanacearum
WP_011301090 305 EEALVRECSQQVAQAVEAYLALPPPDPAAMFDCLYATMPAALQEQLATA 353 Cupriavidus pinatubonensis
WP_002809958 302 EQSLQTELTQQVEEAVQKYLDTPPQPPESMFDDLYESLPSAPREQRQTA 350 Nitrosococcus oceani
WP_012570222 307 EAVLQKELAQEVDQVVEEFLTMPPPKATDMFDYLYAELPVSLEKQREEL 355 Coxiella burnetii
WP_011081422 303 EQQWLAHCKQQVEQAVAHYLSLPPQAPESAFDYLYASLPVELHAQRDML 351 Vibrio vulnificus
WP_031804706 303 EQALVGECQARVQEAVERFETFAAQAPQALFEHVYARWPAVLEEQREQL 351 Pseudomonas aeruginosa
WP_004514777 303 AAEMKGKAGGEIDEAVRRYESVPPPAPGEMFNFVSGELSARLRRQRETs 351 Geobacter metallireducens
WP_003486391 306 EDAWKADCSARVDEEVNAYLNTPVQPVEAMFDYLYGDPPAELLAQRAEv 354 Xanthomonas
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap