3ZGZ,6Q89,1H3N


Conserved Protein Domain Family
LeuS

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COG0495: LeuS 
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Statistics
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PSSM-Id: 440261
Aligned: 760 rows
Threshold Bit Score: 1046.95
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3ZGZ_A        21 M----------------------------------QE------Q-Y--RPEEIESKVQLHWDEKRTFEVTEdESKEKYYC 57 
WP_011414797   1 Mset----------------------------petQSsgtlldQpFreNFDAIEAYARDVWAAENVDACDLdSDKPKRYV 52 
WP_012802605   1 M-----------------------------------K------E-Y--NPHEIEPRMQQAWAAADLFHVTEdADKPKKYV 36 
WP_081433514   1 MdywrhqvfclvthlykkgelveneevqnvsttgdFP------V-Y--DAEAIETKWQRIWEEQNLYKTEEdSSRPKKYV 71 
WP_041691696   1 M-----------------------------------K------P-Y--NPHEIEPRWQKEWDDADLYKVTEdPSKSKKYV 36 
WP_013708897   1 Mcddtv-------------------------hnmdVP------D-Y--DAGRIEKKWMRIWDDENLFALNEnSARPKRYV 46 
WP_022740777   1 M-----------------------------------K------A-Y--NPHEIEPRLQLAWEEAGLYTVPEnSDAPKKYV 36 
WP_066660513   1 M-----------------------------------K------E-Y--NPREIEPRLQQAWADAELDKVNEsADKPKKYV 36 
WP_126421688   1 Msdvndtn---------------------atqasrFP------A-Y--DAAAIEGKWQRIWDEKGTYKTDEdPNKPKKYV 50 
WP_079535292   1 M-----------------------------------K------E-Y--NPSVVEESIQAAWEAEGANHVDEnSTKPKKYI 36 
3ZGZ_A        58 LSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMK-NQLKMLG 136
WP_011414797  53 LGMFPYPSGNAHMGHVRVYAISDAVARLSRFRGFETLHPLGWDAFGLPAENAAIQNNADPAEWTQRNIATMKdEQFSRLG 132
WP_012802605  37 LEMFPYPSGDIHMGHVRNYSIGDVVARYNGMRGFNVLHPMGWDAFGLPAENAAIKHHSHPATWTYANIETQK-ASFKRMG 115
WP_081433514  72 LEMFPYPSGDLHMGHARNYTIGDAMARQARMRGFDVLHPMGFDAFGLPAENAAIKHNTQPSVWTHKNIDQAV-KTMFRMG 150
WP_041691696  37 LEMFPYPSGDIHMGHVRNYTIGDVVARYYKMRGFDVLHPMGWDAFGLPAENAAIKCNSHPAKWTYANIDTQK-ASFKRMG 115
WP_013708897  47 LEMFPYPSGDLHMGHVRNYTIGDAMARAARMRGFDVLHPIGFDAFGLPAENAAIKHRTQAAAWTYRNMECAL-ATMRRMG 125
WP_022740777  37 LEMFPYPSGDMHMGHASNYTYGDVVARYSKMQGFDVLHPMGWDAFGLPAENAAIKHHSHPAIWTYENIETQK-KSFSRMG 115
WP_066660513  37 LEMFPYPSGDIHMGHVRNYSIGDVVARYNRMRGFDVLHPMGWDAFGLPAENAAIKRNSHPATWTYANIETQK-ASFKRMG 115
WP_126421688  51 LEMFPYPSGDLHMGHARNYTIGDAMARQARMRGYDVLHPIGFDAFGLPAENAAIKHNTQAAAWTYQNMDNAL-ATMRRMG 129
WP_079535292  37 LEMFPYPSGDIHMGHVSNYTYGDCLARYWRMCGFEVLHPIGWDAFGLPAENAAIKHNTHPSKWTYSNIDTQL-ASFKRMG 115
3ZGZ_A       137 FGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKIT 216
WP_011414797 133 LSFDLDQEINSASPEFYKWTQWLFQTLYDHDLVYRANGWVNWDPVDQTVLANEQVIDGKGWRSGAPVERRQLPQWYVRIT 212
WP_012802605 116 FSYDWDRTVVACDPEYYRWGQWMFLQFWKRGLVERRNSPVNWCPSCKTVLANEQVVDGRCWRCGSVVEKRDLTQWYLKIT 195
WP_081433514 151 FAYDKDRMFNTCDPEYYKWGQWIFLKMLEKGLVYRATSPVNWCPNDKTVLANEQVVNGKCWRCGAVPEKRELSQWYLRIT 230
WP_041691696 116 FSYDWDRTVVACDPEYYRWGQWIFLQFWKRGLVERRNSPVNWCPNCATVLANEQVTEGECWRCHGAVEKRDLTQWYFKIT 195
WP_013708897 126 FSYDMDRLQQTCSPEYYRWGQWIFEKLWERGLVYRKKSPVNWCPGCKTVLANEQVVNGRCWRCDSLPERRDLEQWYFRIT 205
WP_022740777 116 FSYDWDRKVVACDPEYYRWGQWIFLKFWERGLVERRNSPVNWCPSCGTVLANEQVIEGRCWRCDSEVEKRDLTQWYYKIT 195
WP_066660513 116 FSYDWDRTVVACDPEYYRWGQWIFEQFWKRGLVERRNSPVNWCPGCQTVLANEQVIEGRCWRCDSEVEKRDLTQWYFKIT 195
WP_126421688 130 FSYDYDRLVRTCDPEYYKWGQWMFLKMWEKGLAYRATSPVNWCPSCNTVLANEQVVEGRCWRCGSVPEKRELSQWYLKIT 209
WP_079535292 116 FSYDWDRIVRTCDPEYYKWGQKLFLEFWKKGLVERRESPVNWCPKCKTVLANEQVTEGVCWRCSSVVEKRNLTQWYFKIT 195
3ZGZ_A       217 AYADELLNdLDKLDh-WPDTVKTMQRNWIGRSEGVEITFNVNDy----------DNTLTVYTTRPDTFMGCTYLAVAAGH 285
WP_011414797 213 RFAQSLWDgLDTLQghWSDEAIAVQRGWIGRSEGVEIEFPVLGe---------gGHTIRCYTTRADTIFGVTSITLAPEH 283
WP_012802605 196 DYAQELLDdLDQLTg-WPDRVRQMQANWIGRSEGAEVDFILCDkggavpenpsdHDRITVFTTRADTLFGCSFFVLAPEY 274
WP_081433514 231 DYAQELLDdLDQLEg-WPERVRAMQANWIGRSEGAEIDFILADtdgv----tptDTKMTVFTTRADTIYGCTFMLLPPES 305
WP_041691696 196 DYAQELLDdLDQLDg-WPERVKQMQANWIGRSEGAEIDFVLCGpdgeapaeptaDDVITVFTTRPDTLFGCSFFLLAPEY 274
WP_013708897 206 EYADELLAdLDKLPg-WPERVKQMQANWIGRSEGADIDFILCDsdge----pdpDQRITVFTTRADTLFGCTFFLLSPEY 280
WP_022740777 196 DYAQELLDdLDQLEg-WPERVKQQQANWIGRSEGANVDFILCDrdgnapaepteDDIITVFTTRADTLFGCSFFLLAPES 274
WP_066660513 196 DYAQELLDdLDQLEg-WPERVKQQQANWIGRSEGAEVQFALCDadg-----netDDLITVFTTRADTLFGCSFFVLAPEY 269
WP_126421688 210 DYAQELLDdLDKLTg-WPENVKAQQRNWIGRSEGAEIDFTLADkdgv----tptDRKITVFTTRADTLFGVSFFLLPPES 284
WP_079535292 196 DYAEELLDdLEKLPg-WPANVKQQQANWIGKSEGANVDFVVEPldgvt--tpadGETITVFTTRADTLFGCSFFVLAPEY 272
3ZGZ_A       286 PLAQKAA---ENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHD 362
WP_011414797 284 PLVKDLAa-tEVQGKVEEYIAFATNRSELER--ETAERTGVALGAKARNPLTGEDLPIYISEYVLGGYGTGAIMNVPAHD 360
WP_012802605 275 KGLIDLVvgtEYEQPVRDLIDATAQVSAVERAQGDREKHGVFTGRYVINPINGEKVPVWVADYVVADYGTGAVMAVPCGD 354
WP_081433514 306 KLAAELVgdsEYKAAFDALHEEAVKVSSIDRQGTDREKHGVFTGRYAINPVTGRTVPIWVADYVLLDYGTGAVMGVPSGD 385
WP_041691696 275 KGLMELVegtEYEAAVREVVEGVAKVSAVERAQGDREKHGAFTGRYMVNPVNGEKVPVWVADYIVSDYGTGAVMAVPCGD 354
WP_013708897 281 DGLIDLVegtSWEAGVRAVIEGAQRVSAVERAQGTLEKHGAFTGRYVVNPVSGQRVPVWVADYIVSDYGTGAVMAVPCGD 360
WP_022740777 275 KLLRGLVegtEYEASVMELVEAAKKVTAVQRAQGDHEKHGAFTGRYVVNPINGEKVPVWVGDYIVADYGTGAVMAVPCGD 354
WP_066660513 270 PRVAELVagtEYEKPVMDLVEASKKVTAVQRAQGDHEKHGEFTGRYVVNPINGQKVPVWVADYVVADYGTGAVMAVPCGD 349
WP_126421688 285 PLAAELVagtECEAAFKELKEATEKVSSVDRQGSAREKHGVFTGRYVINPINGRPAPIWVADYVLMDYGTGAVMGVPCGD 364
WP_079535292 273 AGLHDLVhgtDKESEVIEFAEKAAKVSAVERAQGDHEKHGVFTGRYVKNPVNGELVPVWVADYVVADYGTGAVMAVPCGD 352
3ZGZ_A       363 QRDYEFASKYGLNIKPVILAADGSe-PD--------------LSQQALTEKGVLFNSGEFNGL---DHEAAFNAIADKLT 424
WP_011414797 361 ARDFDFARTNGLPIRQVILPAKDA--PEg-------------DLDEAYTDPGFMTNSGQFDGM---STHEAKHAIIDHLV 422
WP_012802605 355 QRDFEFARKYDLPIVPIILDKDDElyNQlkdehg--rvvttvDWDAAFAAEGWLVQSGKYTGLkggKHSEGESAIVADLE 432
WP_081433514 386 KRDFDFAKKYDLPIVPIICEEGTDiyEElkgvsd--ykvtsvDWDGPMDTVGVLVQSGPFTGLrggKHSEAEEAVVAYLT 463
WP_041691696 355 QRDFEFARKYDLPIIPIILGEDDPlyPQlngvqe--rrvtsvDWEAAYDAEGVLVQSGKYTGMvggKHSPAVDAIIGDLA 432
WP_013708897 361 QRDFEFARKYDLPIVPIILSDEDRlaLEesgesidtyngesvDWDRAHTAEGTLVQSGKYTGLrggKHSEGEAAIVADLE 440
WP_022740777 355 QRDFEFARKYDLPIIPIILPEDDPlyPQlkdeqg--rvvttvDWPEAYAAEGMLVQSGPYTGMtggKHSEGEAAIVAALE 432
WP_066660513 350 QRDFEFARKYNLPIIPIILGDDDPlmEQlagekn--rvvtevPWEEAMDAEGTLVQSGPYTGMrggKHSEGEAAIVAALE 427
WP_126421688 365 QRDFDFAKKYGLEIAPIICEKDDPlyDElkdere--lkvtsvSWDHAMDAEGYLVQSGEFTGLkggKHSEAVDAIIGWLS 442
WP_079535292 353 QRDFEFAKKYDLPIIPIILKEDDPlfEQlhgekn--rvvtsvDWEQAMEAEGVLVQSGDFTGLvggKHSEGEKKIVDFLE 430
3ZGZ_A       425 AMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGI-TSPIKADPEWAKTT--VNGM 501
WP_011414797 423 EQGLGTRKVNFRLRDWLISRQRFWGAPIPMVHSDEHGWAKAP--DLPVMLPKDVDFSQGsGKAMASAPGFLETTfpGTSD 500
WP_012802605 433 ARGCGRRKVEFRLRDWLISRQRYWGNPIPAIHCPTCGVVPVPEEDLPVRLPEDIDLAA--GETLATHEGFVKCTcpRCGG 510
WP_081433514 464 EHSVGRRTVQFRLRDWLISRQRYWGNPIPMIHCDCCGDVPVPYDQLPVMLPDNLDLAA--GDTLAECKEFVETTcpKCGK 541
WP_041691696 433 AEGKGKKTVQFRLRDWLISRQRYWGNPIPAVHCPECGLVPVPEEDLPVRLPEDIDLAA--GETLATHEAFVNTTcpVCGG 510
WP_013708897 441 DAGVCRRKVEYRLRDWLISRQRYWGNPIPAIHCAHCGIVPVPVDELPVVLPEDLDLGA--GETLASHPEFYETTcpICGE 518
WP_022740777 433 EMGRGKRTVEFRLRDWLISRQRYWGNPIPAIHCEKCGVVPVPEEDLPVRLPEDIDLAA--GETLATHAGFVNTTcpVCGG 510
WP_066660513 428 EAGRGKRKVEFRLRDWLISRQRYWGNPIPAIHCPECGVVPVPEEDLPVLLPKDIDLAA--GETLASHEEFCSCTcpKCGG 505
WP_126421688 443 ERGLGRKKVQFRLRDWLISRQRYWGNPIPMIHCDCCGDVPVPYDQLPVTLPDNLDLGA--GETLAEYAPFYETTcpKCGR 520
WP_079535292 431 EKKAGHRTTEYRLRDWLISRQRYWGNPIPAIHCEKCGVVPVPEKDLPVLLPEDIDLSN--GETLATHKSFAECTcpVCGA 508
3ZGZ_A       502 PALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAK 581
WP_011414797 501 PAIRETDTMDTFMCSSWYAWRYLDAKNGEQAFRESRAEDWMPIDYYVGGLEHASQHLIYFRFISHFLHAIGMTPTSEPVK 580
WP_012802605 511 EARRETDTMDTFTCSSWYYLRYTDPHNDTVPFARDNANRWMPVDQYVGGIEHAILHLLYSRFFTKMLRDMGMLDFNEPFT 590
WP_081433514 542 PAKRITDTMDTFTCSSWYYLRYCDPHNTELPFSKESVDRWMPVDNYIGGIEHAILHLLYSRFFTKVLRDLGMIDIDEPFK 621
WP_041691696 511 PAKRETDTMDTFTCSSWYYLRYTDPHNEELPFAPEKANRWMPVDQYIGGIEHAILHLLYSRFYTKVLRDLGLLEFDEPFS 590
WP_013708897 519 PARRETDTMDTFTCSSWYYLRYCDPHNTDLPFSRAAASRWMPVDNYVGGIEHAILHLLYSRFFTKALRDIGLLDIDEPFE 598
WP_022740777 511 PAKRETDTMDTFTCSSWYYMRYTDPHNVHAPFDPEKTNAWMPVDQYIGGIEHAILHLLYSRFFTKVLRDCGLLDFDEPFT 590
WP_066660513 506 PAKRETDTMDTFTCSSWYYMRYTDPHNQDAPFDSAKANRWMPVDQYIGGIEHAILHLLYSRFYTKVLRDCGLLNFDEPFT 585
WP_126421688 521 PAKRITDTMDTFTCSSWYYLRYCDPHNTELPFSKESVDRWMPVDNYIGGIEHAILHLLYSRFWTKVLRDLGMIDADEPFT 600
WP_079535292 509 PAHRETDTMDTFTCSSWYYLRYADPHNDKEPFSPELANKWLPVDQYIGGIEHAILHLLYSRFFTKVCRDLGMVDFDEPFE 588
3ZGZ_A       582 QLLCQGMVladafyyVGENGernwvspvdaiverdekgrivkakdaaghelvytgmSKMSKSKNNGIDPQVMVERYGADT 661
WP_011414797 581 NFLDNGLVk--------lGG------------------------------------EKMSKSKGNVVIPTEAVDKYGADA 616
WP_012802605 591 NLLTQGMV-------KDAHG------------------------------------ETMSKSKGNVIAPEDMIAHYGADA 627
WP_081433514 622 NLMTQGMV-------KDEHG------------------------------------DTMSKSKGNVVPPSSVIEPYGADT 658
WP_041691696 591 NLLCQGMV-------KDEHG------------------------------------ETMSKSKGNVIAPEDMIAEYGADA 627
WP_013708897 599 NLLTQGMV-------KDEHG------------------------------------EVMSKSVGNVIAPATVIEPYGADT 635
WP_022740777 591 NLLCQGMV-------LDAHG------------------------------------DVMSKSKGNVVSPEEMIAEYGADA 627
WP_066660513 586 NLLCQGMV-------LDEHG------------------------------------DVMSKSKGNVIAPETMIERYGADA 622
WP_126421688 601 NLLCQGMV-------KDHNG------------------------------------ETMSKSKGNVVPPSSVIEPYGADT 637
WP_079535292 589 NLLCQGMV-------LDSNG------------------------------------EVMSKSKGNVVSPEEMIKKYGADA 625
3ZGZ_A       662 VRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKgdva-------alnvD--------AlTENQKALRRDVH 726
WP_011414797 617 LRLYILADTPLRRDIDWDDSGIEGKQRFLSQIWTLAGQIASApale--------gepA--------PgTDAEKAAMRELA 680
WP_012802605 628 VRTYILFMAPPDKDLQWDEEGLAGIYRFLTRVWRQVNDLMGKagest------lfdpTaqnagkasSvEQAAKVLRRERH 701
WP_081433514 659 MRLAILFVAPPEKDFDWDEKAIAGANRFIKRAWRVVWELSRTadasa------vldhT--------AlDSKSLELNRVLN 724
WP_041691696 628 VRAYILFMAPPDKDLLWDEGGLAGIYKFMNRAWRIVNDLMGAadeet------lyqpGas----edEgIKALEQLVRERH 697
WP_013708897 636 LRLAILFIAPSEKDFSWDANAVEGANRFLRRAWRVVWRLSRDagedalsatcssldkS--------SlDDAALALLRERH 707
WP_022740777 628 VRAYILFLGPPEKEKLWNEDGLPGMYKFLNRLWRQVHDLCGKagdet------lfaqKpa----deAaVAAAKKLIRERH 697
WP_066660513 623 VRAYILFMAPPEKELLWNEDGLAGVHRFLVRVWRQVHDLLGIageet------lfdpEavndkkapApADAAKTLLRERH 696
WP_126421688 638 MRLVILFIAPPEKDFDWDEKAVAGANRFIKRAWSIVWQLSAGahag-------efdaR--------SlKGQAGELFRTLN 702
WP_079535292 626 VRAAVLFMGPPDKEKLWNEDGLAGMLKFLKRVWRQVYDLKGNageet------ffeeTqa-----gKaEVTAKDLIRVRH 694
3ZGZ_A       727 KTIAKVTDDIGrRQTFNTAIAAIMELMNKLAKAPT---Dg-----eQDRALMQEALLAVVRMLNPFTPHICFTLWQ-E-L 796
WP_011414797 681 KIAKEVAEDLEeRRGFHNAIARLHSFVGELRPLVAg--As-----dAEKPLLRHVMAEFMKVLGVFAPHMAEYLWR-EaF 752
WP_012802605 702 RVVGKVTNDME-RNSFNTAIAAIMELSNAVGSYVRvasAemraadpELAALDREVAEVLVKLLSPMAPHWADELWEtV-L 779
WP_081433514 725 AMGIRCTTEFD-KGQFNTAISAVMELVNAASAYINevpAe-----sRDAALCYKVANDVVAMLAPIIPHWAEELSHeA-L 797
WP_041691696 698 RVVGKVVDDFD-RNNFNTALAAIMELTNAASDYLRkcsPeeragceGSRAVDAEVAEVLVKLLAPFAPHWAEELWHaV-L 775
WP_013708897 708 RAIAKCTADFD-RHQFNTAISAVMELVRAASAWVGsk-------grRDPALCGLIATDIVSVLAPICPFWADELWHeA-L 778
WP_022740777 698 RVVEKVSADIE-RNNFNTAIAAIMELSNAAGEYLRafsPedraaceDHRALDAEVAEVLVKLVAPFTPHLADELWReA-L 775
WP_066660513 697 RVVGKVTDDFE-RTNFNTAIAAIMELSNAAGAFLRvtnAeqr--aaEYADMAAEVASVLVRLLAPVAPHWADELWQtA-L 772
WP_126421688 703 GLGARCTSDYD-RGQFNTAISAVMEIVNAASKYLNetpAe-----dRVLELDFRVAHDIVAILAPICPHWAEELYHeA-L 775
WP_079535292 695 ATVKKVTEDFK-RNNFNTAIASIMELSNAIGAFLRsnsKnlrendkQLKDLCDDVAETIVELLFPMTPHFCDQLYR-D-L 771
3ZGZ_A       797 -KGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLL 875
WP_011414797 753 -GMSASLFSQPWPDPGEQYLVADELTISIQVNGKLRATVSVPADAGEEQVVEIAKADAKVAEYLGSGTLRRTIFVPGRLV 831
WP_012802605 780 -DNQGYLYGCVWPTFDAQAAQADEVELAIQINGKVRAHITVGADAAEDEVREQAL--AAIKDQTEGQTVAKAIVIPGRLV 856
WP_081433514 798 -GKDVPVYHQPWPEFDPEQAKSNTVEIAVQLKGKVRARIEVSADASEEELTAAAT--KAIADQLEGKEIKKVIVVKGRLV 874
WP_041691696 776 -GKDGSVHTQPWPEFDPEQAKADEVELAVQVNGKVKAKIMVAADAAEDDIKAVGL--AAVEAALEGKDVKKVVVVPGRLV 852
WP_013708897 779 -GHAADVYSAPWPAFDPEEAASDTVEIAVQVMGKLRTRSVVPSGATNEEMRLAAE--HAARKWIADKTVVKAIVVPGRLV 855
WP_022740777 776 -GREGFVYDQPWPEYDPDQARADEVELAVQICGKIKGRVTVAADAPEPEVLAAAR--EAVAAALEGKTVKKEVYVPGRLV 852
WP_066660513 773 -GNEGSVHRAEWPTFDPEAAKADEVELAVQINGKVRARINVAASAAEDDIRAQAL--EAISAYTEGKNVLKAIVIPGRLV 849
WP_126421688 776 -HLEGSVYNEPWPEFDPELAKADTVEIAVQVMGKVRGHATIAADATREQTEKAAL--AAISEQLEGKTVRKVIVVPGKLV 852
WP_079535292 772 iKTGGRATEATWPSFDEALCVADEVEIAVQLLGKVKARIMIPADCEKETAI--ARAKEAISQDLEGKTVVKEIFVPGRLV 849
3ZGZ_A       876 NLVVG 880
WP_011414797 832 NFVVG 836
WP_012802605 857 NIVVR 861
WP_081433514 875 NIVA- 878
WP_041691696 853 NIVAK 857
WP_013708897 856 NLIVR 860
WP_022740777 853 NIVAV 857
WP_066660513 850 NVVVK 854
WP_126421688 853 NVVAN 857
WP_079535292 850 NVVAK 854
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