Conserved Protein Domain Family
PRK06292

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PRK06292: PRK06292 
dihydrolipoamide dehydrogenase; Validated
Statistics
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PSSM-Id: 235774
Aligned: 212 rows
Threshold Bit Score: 403.789
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
289581474  28 IDEYDLVVLGGGS-GSQVATAAVDEGHTAAVVEP-GPLGGACVTRGCIPSKALIHRADIVDELHRA-AEFGVHADL--QE 102
16081358    1 MEEYDVITIGAGGaAYPAAFRLKRSGFSVLMIDKkGVMSGNCLAEGCVPSKAVIETVHNLAKMRHF-GDYSIDYS---KI 76 
13542217    1 METYDVITLGAGGaAYPAAFRLKKSGYSVLMIDKkGIMSGNCLAEGCVPSKAIIETVHNYSKL----KKFGK------YS 70 
48477959    1 MKEYDVVTIGAGGaAYPAAFKLKRSGYNVIMIDKkGVMSGNCLSEGCVPSKAIIESVHKYNTLKGIfD----------FK 70 
189219213   4 ELSVDVAILGAGGgGYPAAFFLDKSGFKVLMVDPiGNLGGNCLAEGCVPSKAVREASLVRATAKKY-PFFGLSGMV--PQ 80 
195953613   1 MIEVDVLTIGAGGgAYPGAFRLAKAGFSVLMVDKkGVMSGNCLAEGCVPSKAIREQIHTYLRFKAF--------SKkdID 72 
198283675   3 IQYADLLTIGAGGgAYPAAFRLARAGRSVVMVDPkGLMSGNCLYEGCIPSKAVRETAEIYQSQRRF-AERGLPGT---IT 78 
218665061   3 IQYADLLTIGAGGgAYPAAFRLARAGRSVVMVDPkGLMSGNCLYEGCIPSKAVRETAEIYQSQRRF-AERGLPGT---IT 78 
256371111   4 EATADVVIVGAGGgGYPAAFALDRAGRSVVLVDPiGNLGGNCLAEGCIPSKAVREASLIRARSTRA-ETFGLRGTA--LD 80 
296136265  13 SDDVDVLVLGAGGaGYPGAFFLAKAGRSVLMVDPiGNLGGDCLAEGCVPSKAVREAALVRGLADKF-DGFGLRGSK--PT 89 
289581474 103 IEFGEFTAAIHDTVY-EKADNQe-SSLDDTDGLTRYHGTGRFVDDRTIVVesddenasqsdssTPSQIR-GDTIIIAVGG 179
16081358   77 VDHKDSVQNIRYEQH---------DQELKEAGLKIIKGTARIIDDNTVEVss---------dtGTSRYRsSSAIIIASGS 138
13542217   71 IAYEDIVKHKDDVQN---IRYKqhDEELHEAGLKILKGTAKLIDENTVEVet---------dtGKERYR-AESIIIGTGS 137
48477959   71 VDYKKIVDHKDSVQR-LRYSDH--DRELGEADLKIIKGTGRLVDENTVEVdt---------gtGIERYH-ADNIIIATGA 137
189219213  81 VDWKAILAHKDKVQN-TRYALH--KEEINRSNILFYKGVGKIVDEKKIEVit----------dKENFLVfFKFLIIATGS 147
195953613  73 IDYKDIIAKKDEVQNiRYKLHE--EELKAFKNLKLMKGVARFKDEHTVVVes---------dkGEETIK-AKYIIIASGA 140
198283675  79 VDFAKIMAHKDSIQA-RRYQQHa-ADLAATPNIQLIQGEARFITPHEVAVdt---------adGERRFR-CAQVIIASGS 146
218665061  79 VDFAKIMAHKDSIQArRYQQHA--ADLAATPNIQLIQGEARFITPHEVAVdt---------adGERRFR-CAQVIIASGS 146
256371111  81 VDWSGVLAHKDRVQRlRYEQHT---DELRASTIRFMTATARIDDAERIAIeea--------dgSTTLVR-FHDLVLATGS 148
296136265  90 VDWGAVLAHKDRVQN-TRYEQH--AREIAAGGVAFVQGRGVIVAPDRARIdagd-------gsgsREVR-FRQLILGTGS 158
289581474 180 RpvIPPIGGV----EDVDYLTSEDALFLDEQPDSLVIVGGGYIGAELGYFFGALGTEVSLVGRSEQLVPREDDDVSEVVT 255
16081358  139 EtfVPKIPGAelawTSADLYSLKP--KVKKLPKSIAIIGGGYIGMETASFMSILGVKVTVIEMLDRVMSTMDEAMVDKLL 216
13542217  138 DtyVPKIPGAelawTSRELYALNP--KVRKLPKSIAIIGGGYIGLETASFMSLLGTDVTVIELLDRVLSTMDSGMVSKLV 215
48477959  138 DtfIPNIKGSelavTSRDFYSMDP--KIKSVPESITIIGGGYIGVETGSFLSILGSRVTIIEMLDRILESMETDIIDKLI 215
189219213 148 RphSLPIAGSdlavNSHDLFKLNATV---PFPSKPIIIGGGYIGVEVASMLENLGAKPSILESTELLVGGLDRELSLFLA 224
195953613 141 DvfVPPIKGKeyaiTSTDIYKLNP--NLTYMPKEFAIVGGGYIGLETAFYFANLGSNVYIFEKLDRVLAGIDKYATQTLL 218
198283675 147 DvfVPPVPGAefclTSHDLYKPDATL--KTLPERMIVIGGGYIGLETATFFAALGTRVTLLQKGRQLLNGMDPGMVALLT 224
218665061 147 DvfVPPVPGAefclTSHDLYKPDATL--KTLPERMIVIGGGYIGLETATFFAALGTRVTLLQKGRQLLNGMDPGMVALLT 224
256371111 149 ApsRLAIAGAdlavTSHELFRLGADL---PFPSRPVIIGGGYIGVETASMLANLGAAPTILEATGGLLPGYDAALATGLA 225
296136265 159 ApaRLPILGAdlalTSHDLFRLGADL---PLPQHLVIIGGGYIGVETASMLQALGAQCSILEYAPQVLPGFDAELASFLH 235
289581474 256 DALESHCELYTGYEAAAVE--ETDD-GIVVtaepsddggsgdegddsgendneenSDESVELEAERLLFATGRRPNTDSl 332
16081358  217 PLLPK-MDIRTASPVQSIE--RNGSmyhv----------------------nfgkEGEKESIEVEAVLMAVGRVPVFPE- 270
13542217  216 PLLPK-MNLILSSPVKEIR--RGGDmfev----------------------sydhEGKTEKIRVEAVLMAVGRMPMFPE- 269
48477959  216 PLLPR-MDVKTSSEVKSIE--KFNDkl--------------------------kvLLNDGEVVSDMVMMAAGRHPVLPE- 265
189219213 225 EKLKTRIHIELGAKVESIE--KDRD--KFKvvy--------------------qkNNQAHTLEGDLVIMATGRECLTPE- 279
195953613 219 KYLPKNIKIFTSVEVQEIGlkDKKKvvy------------------------ykqDDTVKSIEVDEVLMAVGRKPIIP-- 272
198283675 225 PLLDPSIRILTGVDVTAVE--VTPEggrrv---------------------hythGEENDTLDGDVVLMAVGRRPVIPA- 280
218665061 225 PLLDPSIRILTGVDVTAVE--VTPEggrrv---------------------hythGEENDTLDGDVVLMAVGRRPVIPA- 280
256371111 226 SLLGQRVQLHVDALVRSIT--RVGSdyev----------------------swqhGGDVHVTRGDLVIMATGRHVQLPE- 280
296136265 236 ASLSQRVRIECSAQVLSIA----RDgDGYHvry--------------------kqGGGERSLQGDAVLMATGRVAVLPE- 290
289581474 333 DLEKTGVETDDSGHIEVDEQLAT------TADDIWALGDVLANEPYKHAADYETRIVTANV--LDd--AGEEVDYHAMPH 402
16081358  271 GIDDLGIEHDRHGIK-VNMAMQT------NIKNIYATGDVNGITPLFHAAKRQSLVAANNI--MAnnvPIDYFDPLSVPF 341
13542217  270 GLDDLGIKYDKHGIK-VNMAMQT------NIKHIYATGDVNGLTPLFHAAKRQSLVAANNI--MAnhvPVDYFDPLSVPF 340
48477959  266 GLDDLGIKYTKHGIN-VNMSMQT------NIKNIYATGDVNGITPLFHAAKRQSIIAANNI--MSgnvPVDYFDPISVPF 336
189219213 280 -------GIEKLGFPSSKPLPVTsflqlyDFPHIYAPGDINGKSMLFHSAVLQSIIAAHNIaaGGq--PVSRMDWKSVPY 350
195953613 273 --EGADKFLKISKAIEVNRACQT------NIPHIYASGDVNGKIPLFHTATRQSIVCAYNI--MAnntPIDYADFENVPF 342
198283675 281 GAAEIGITVTRKGVA-VGPDLQT------VHPHIYACGDVNGRVPLFHAAVRQSMVAAHNI--LGgniPMDYADFRHIPT 351
218665061 281 GAAEIGITVTRKGVA-VGPDLQT------VHPHIYACGDVNGRVPLFHAAVRQSMVAAHNI--LGgniPMDYADFRHIPT 351
256371111 281 GIDALGLAPDRAPT--VDAQLRT------SHPRVWAPGDVNGRTPLFHAAVRQSLVVAHCI--MAggrSTDAMDFDAVPT 350
296136265 291 GVEHLGLAME-RGHVKVDDTLRT------SNPQVWAPGDINGRSMLFHSAVRQSLVAAHCI--AAggqAVDRMPFHAVPM 361
289581474 403 AIFTSPQVASVGQTEGAL-EERGLE--YQSANIPFGTAPLGMILD-ADGFVKVLASPE-GEILGCHIVGPHASTLIQEVV 477
16081358  342 TVYTIPQMAYVGILPSQA-RKMGIE--YLETDYQIEKDALAQINNeMFGEIRIFTDKRm-KVIGGYVIGNDAGNVINEIA 417
13542217  341 TVYTVPQVAYVGILPDQA-KKLGIS--YIETDYQMEKDAMAQVNSeMEGEIRLFFDSRm-KIIGGYVIGNDAGNLINEIA 416
48477959  337 TLYTIPQLAYVGILPAQA-ERLGIE--HYEATYDMKKDSLAEINNeVYGEITLVFDKRm-KIIGGYVIGNDAGNIINEIA 412
189219213 351 TVFTEPEIAGVGLTEEEAlHLYGQH--VEIVKYDYAVDSRAEILGeTEGFIKLLFDGEnKRLLGAHIAGVEASQLIAPLA 428
195953613 343 TVFTIPAMAFVGITKEKA-ESLNMD--IVETSFDLKEDSRAEIYS-EEGELKLFFDAKsLKLVGASIVGIDAEQLVSHLG 418
198283675 352 TIFTLPAAAYVGITPALA-EAQGIP--LQTGRYDFEEDSRAQILErMEGGIQLFFAADsLRLLGGWVVGIDAGSLIGQIG 428
218665061 352 TIFTLPAAAYVGITPALA-EAQGIP--LQTGRYDFEEDSRAQILErMEGGIQLFFAADsLRLLGGWVVGIDAGSLIGQIG 428
256371111 351 TVFTEPEVASVGLTEVEA-RTRHGD--VMVGHYDFAGDARAQILDeREGFLALIAEPHrGTLLGAQVLGVDAAQLIAPLA 427
296136265 362 TVFTEPELAHAGQTAAQAeAA-LGAdaVAVMRYDYAEDSRAQIYAeTQGFIKLVFNRHdARLLGAQIAGMDAAQLIAPLA 440
289581474 478 TAMDSGsGMVEDVAEPVHVHPALSEVVYAAFDELSS 513
16081358  418 LAVSKG-LSLRDLAEMAHQHPMTFEGIDSAARKLY- 451
13542217  417 LGISKG-LSARDFAEMAHQHPMSFEGLDSAARKLY- 450
48477959  413 LCVSRG-LSLRDLAEMSHQHPMSFEGLDSAARKFY- 446
189219213 429 LAIREG-LDAEALAHVAFPHPMISEGINKAARTFSP 463
195953613 419 LAIKLG-ATARDLVEYQDQHPMTQECISKAARKLF- 452
198283675 429 TAAAHG-LTAYDLARFADQHPMSAEGIGKAARSLF- 462
218665061 429 TAAAHG-LTAYDLARFADQHPMSAEGIGKAARSLF- 462
256371111 428 LAIHAG-LTVDQLATMAFPHPMASEGIDRAARSLRP 462
296136265 441 LALEQG-LGAKALADTVFPHPMLSEGINKAARAFKL 475
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