Conserved Protein Domain Family
Agg_substance

?
NF033875: Agg_substance 
LPXTG-anchored aggregation substance
Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Statistics
?
PSSM-Id: 411439
Aligned: 4 rows
Threshold Bit Score: 2490.72
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2_ncbifamImport    1 MKQQMKAKKQYKTYKAKNHWVTVPILFLSVLGAVGLATDNVQAAELDTQPETTTVQPNNPDLQSEKETPKTAVSEEATVQ 80  
4_ncbifamImport    1 MNQQTEVKKRFKMYKAKKHWIVAPILFLGVLGVVGLATDNVQAAELDTQPGSTTVHPDNPDPQLGSATPNTAVSEESAVQ 80  
1_ncbifamImport    1 MNQQTEVKKRFKMYKAKKHWIVAPILFLGVLGAVGLATDNVQAAELDTQPGTTTVQPDNPNPQSRNETLKTAVSEEAALQ 80  
3_ncbifamImport    1 MKQQTEVKKRFKMYKAKKHWVVAPILFIGVLGVVGLATDDVQAAELDTQPGTTTVQPDNPDPQVGSTTPKTAVTEEATVQ 80  
2_ncbifamImport   81 KDTTSQPTKVEEVAPENKGTEQSSATPNDTTNAQQPTVGAEKSAQEQPVVSPETTNEPLGQPTEVAPAENEVNKSTSIPK 160 
4_ncbifamImport   81 KDTTSQPTKAEEVASEKNGAEQSSATPNDTTNVQQPTVGAEKSAQEQPVVSPETTNEPLGQPTEVAPAENEANKSTSILK 160 
1_ncbifamImport   81 KDTTSQPTTAEEVVPKGIAAEQSSATSNDTTNVQQPTAEAEKSAQEQPVVSPETTIEPLGQPTEVAPAENDANKSTSIPK 160 
3_ncbifamImport   81 KDTTSQPTKVEEVASEKNGAEQSSATPNDTTNAQQPTVGAEKSAQEQPVVSPETTNEPLGQPTEVAPAENEANKSTSIPK 160 
2_ncbifamImport  161 EFETPDVDKAVDEVKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAK 240 
4_ncbifamImport  161 EFETPDVDKAVDEAKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAK 240 
1_ncbifamImport  161 EFETPDVDKAVDEAKKDPNITVVEKPTEDLGNVSSKDLAAKEKEVDQLQKEQAQKIAQQAAELKAKNEKIAKENAEIAAK 240 
3_ncbifamImport  161 EFETPDVDKAVDEAKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAK 240 
2_ncbifamImport  241 NKAEKERYEKEVAEYNKHKNENSYVNEAISKNLVFDQSVVTKDTKISSIKGGKFIKATDFNKVNAGDSKDIFTKLRKDMG 320 
4_ncbifamImport  241 NKAEKERYEKEVAEYNKHKNENSYVNEAISKNLVFDQSVVTKDTKISSIKGGKFIKATDFNKVNAGDSKDIFTKLRKDMG 320 
1_ncbifamImport  241 NKAEKERYEKEVAEYNKHKNDKGYVNEAISKDLVFDSSIVTKDTKIDKITGGKFIKASDFNKVNQGQSKDIFTKLSKDMN 320 
3_ncbifamImport  241 NKAEKERYEKEVAEYNKHKNENGYVAKPVNKTLIFDREA-TKNSKVVSVKAAEYIDAKKLTDKHK-DKKLLISMLSVDSS 318 
2_ncbifamImport  321 GKVTGNFQNSFVKEANLGSNGGYAVLLEKNKPVTVTYTGLNASYLGRKITKAEFVYELQSSPSQSGTLNAVFSNDPIITA 400 
4_ncbifamImport  321 GKATGNFQNSFVKEANLGSNGGYAVLLEKNKPVTVTYTGLNASYLGRKITKAEFVYELQSSPSQSGTLNAVFSNDPIITA 400 
1_ncbifamImport  321 GKATGNFQSSKVAAVEFGPKGGYAVLLEKNKPVNVTYTGLNASYLDRKITKAEFIYELQSAPSQSGTLNAVFSNDPIITA 400 
3_ncbifamImport  319 GLTTKDSKKAHFYYNNG--AGGTLVVLHKNQPVTITYGNLNASYLGKKIASAEFQYTVKATPDSKGRLNAFLHDDPVAT- 395 
2_ncbifamImport  401 FIGTNRVNGK----DVKTRLTIKFFDASGKEVLPDKDSPFAYALSSLNSSLTNKGG--HAEFVSDFGANNAFKYINGSYV 474 
4_ncbifamImport  401 FIGTNRVNGK----DVKTRLTIKFFDASGKEVLPDKDSPFAYALSSLNSSLTNKGG--HAEFVSDFGANNAFKYINGSYV 474 
1_ncbifamImport  401 FVGTKNANGK----DVKVRLTIKLYDANGKEVLPDKDHAFAYALSSLNSSLGTNYSveHAEFVSDFGSKNEFKYINGSYV 476 
3_ncbifamImport  396 IVYGINIDPRtkkaGAEIEMLVRFFGEDGKEILPTKENPFVFSGASLNSRGENITY----EFVKV-GNTDTVHEINGSKV 470 
2_ncbifamImport  475 KKQADGKFYSPEDIDYGTGPSGLKNSDWDAVGHKNAYFGSGVGLAN--GRISFSFGMTTKGKsNVPVSSAQWFAFSTNLN 552 
4_ncbifamImport  475 KKQADGKFYSPEDIDYGTGPSGLKNSDWDAVGHKNAYFGSGVGLAN--GRISFSFGMTTKGKsNVPVSSAQWFAFSTNLN 552 
1_ncbifamImport  477 KKQADGKFYSTEDLDYGTGPSGLKNSDWDAVGHKNAYYGSGVGLARegGRISFSFGMTTKGK--VNLSGAQWFAFSTNLN 554 
3_ncbifamImport  471 ARHGN-KVYSKTDIDVGT--NGISISDWEAVQGKE-YIGATV--IStpNRIKFTFGNEIVNN-PGYDGNSMWFAFNTDLK 543 
2_ncbifamImport  553 AQSVKPIFNYGNPKEPEKATIEFNRYKANVVPVLVPNKEVTDGQKNVNDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQ 632 
4_ncbifamImport  553 AQSVKPIFNYGNPKEPEKATIEFNGYKANVVPVLVPNKEVTDGQKNINDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQ 632 
1_ncbifamImport  555 AKSIRPYQKKGNPKEPEKATIEFNRYKANVVPVLVPNKEVTDGQKNINDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQ 634 
3_ncbifamImport  544 AKSITPYQEKGRPKQPEKATIEFNRYKANVVPVLVPNKEVTDGQKNINDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQ 623 
2_ncbifamImport  633 GIRDTFDAEKVTIDLSKVKVYQADASLNEKDSKAVAAAINSGRAKDVTASYDLHLDQNTVTAMMKTNADGSIVLAMGYKY 712 
4_ncbifamImport  633 GIRDTFDAEKVTIDLSKVKVYQADASLNEKDLKAVAAAINSGKAKDVTASYDLNLDQNTVTAMMKTNADGSVVLAMGYKY 712 
1_ncbifamImport  635 GIRDTFDAEKVTIDLSKVKVYQADASLNEKDLKAVAAAINSGKAIDVTASYVLNLDQNTVTAMMKTNADGSVVLAMGYKY 714 
3_ncbifamImport  624 GIRDTFDAEKVTIDLSKVKVYQADASLNEKDLKAVAAAINSGKAKDVTASYDLHLDQNTVTAMMKTNADDSVVLAMGYKY 703 
2_ncbifamImport  713 LLVLPFVVKNVEGDFENTAVQLTNDGETVTNTVINHVPGSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERP 792 
4_ncbifamImport  713 LLVLPFVVKNVEGDFENTAVQLTNDGETVTNTVINHVPSSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERP 792 
1_ncbifamImport  715 LLVLPFVVKNVEGDFENTAVQLTNDGETVTNTVINHVPVSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERP 794 
3_ncbifamImport  704 LLVLPFVVKNVEGDFENTAVQLTNDGETVTNTVINHVPGSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERP 783 
2_ncbifamImport  793 ANYGGITKEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNK 872 
4_ncbifamImport  793 ANYGGITEEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNK 872 
1_ncbifamImport  795 ANYGGITEEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNK 874 
3_ncbifamImport  784 ANYGGITEEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNK 863 
2_ncbifamImport  873 VGKQAWSVYLEVERIKTGDVENTQTENYNKELMRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLK 952 
4_ncbifamImport  873 VGKQAWSVYLEVERIKTGDVENTQTENYNKELVRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLK 952 
1_ncbifamImport  875 VGKQAWSVYLEVERIKTGDVENTQTENYNKELVRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLK 954 
3_ncbifamImport  864 VGKQAWSVYLEVERIKTGDVENTQTENYNKELVRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLK 943 
2_ncbifamImport  953 GYDKDFAFDTVDLATGVSFFDDYDETKVTPIKDLLRVKDSKGVDITNQFTISWDDAKGTVTISAKDPQAFILAHGGQELR 1032
4_ncbifamImport  953 GYDKDFAFDTVDLATGVSFFDDYDETKVTPIKDLLRVKDSKGVDITNQFTISWDDAKGTVTISAKDPQAFILAYGGQELR 1032
1_ncbifamImport  955 GYDKDFAFDTVDLATGVSFFDDYDETKVTPIKDLLRVKDSKGADITNQFTISWDDAKGTVTISAKDPQAFILAYGGQELR 1034
3_ncbifamImport  944 GYDKDFAFDTVDLATGVSFFDDYDETKVTPIKDLLRVKDSKGEDITNQFTISWDDAKGTVTISAKDPQAFILAHGGQELR 1023
2_ncbifamImport 1033 VTLPTKVKADVSGDIYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEY 1112
4_ncbifamImport 1033 VTLPTKVKADVSGDVYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEY 1112
1_ncbifamImport 1035 VTLPTKVKANVSGDVYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEY 1114
3_ncbifamImport 1024 VTLPTKVKANVSGDVYNLAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEY 1103
2_ncbifamImport 1113 AGVVEEWSISDKLDVKHDKFSGQWSVFANSNFVLADGTKVNKGDDISKLFTMTFEQGVVKITASQAFLDAMNLKENKNVA 1192
4_ncbifamImport 1113 AGVVEEWSISDKLDVKHDKFSGQWSVFANSNFVLADGTKVNKGDDISKLFTMTFDKGVVKITASQAFLDAMNLKENKNVA 1192
1_ncbifamImport 1115 AGVVEEWSISDKLDVKHDKFSGQWSVFANSNFVLADGTKVNKGDDISKLFTMTFEQGVVKITASQAFLDAMNLKENKHVA 1194
3_ncbifamImport 1104 AGIVEEWSISDKLDVKHDKFSGQWSVFANSTFVLADGTKVNKGDDISKLFTMTFEQGVVKITASQAFLDAMNLKENKNVA 1183
2_ncbifamImport 1193 HSWKAFIGVERIAAGDVYNTIEESFNNETIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVEPELPQ 1272
4_ncbifamImport 1193 HSWKAFIGVERIAAGDVYNTIEESFNNEKIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVVPELPK 1272
1_ncbifamImport 1195 HSWKAFIGVERIAAGDVYNTIEESFNNEKIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVAPELPH 1274
3_ncbifamImport 1184 HSWKAFIGVERIAAGDVYNTIEESFNNEKIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVVPELPQ 1263
2_ncbifamImport 1273 TGEKQNVLLTVAGSLAAMLGLAGLGFKRRKETK 1305
4_ncbifamImport 1273 TGEKQNVLLTVVGSLAAMLGLAGLGFKRRKETK 1305
1_ncbifamImport 1275 TGEKENTLLSVLGA-GMLVGLAWFGLKKR-EVK 1305
3_ncbifamImport 1264 TGEKQNVLLTVAGSLAAMLGLAGLGFKRRKETK 1296
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap