Conserved Protein Domain Family
PRK05446

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PRK05446: PRK05446 
bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB
Statistics
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PSSM-Id: 235471
Aligned: 211 rows
Threshold Bit Score: 589.069
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
262341198   1 MKKILFIDRDGTIIRENPPTYQIDSIEKISFYPKVIFFLSKIvEELNYDLVMVTNQDGLGTEKFPEKIFWPVHNHILNVL 80 
54294141    1 MKKILFIDRDGTLVEEPF-DFQVDSLDKIKLTSGVIPALLQL-QKAGFTFIMVSNQNGIGTVAFPEEDFAVCHEFILDLF 78 
54297154    1 MKKILFIDRDGTLVEEPF-DFQVDSLDKIKLTSGVIPALLQL-QKAGFTFIMVSNQNGIGTVAFPEEDFAVCHEFILDLF 78 
148358783   1 MKKILFIDRDGTLVEEPF-DFQVDSLDKIKLTSGVIPALLQL-QKAGFTFIMVSNQNGIGTVTFPEEDFAVCHEFILDLF 78 
296106828   1 MKKILFIDRDGTLVEEPF-DFQVDSLDKIKLTSGVIPALLQL-QKAGFTFIMVSNQNGIGTVTFPEEDFAVCHEFILDLF 78 
52841430    1 MKKILFIDRDGTLVEEPF-DFQVDSLDKIKLTSGVIPALLQL-QKAGFTFIMVSNQNGIGTVAFPEEDFAVCHEFILDLF 78 
294673215   1 MKKILFIDRDGTLIEEPA-DEQIDSFEKLKFVKGMIRNLAFIrEKLDFEFVMVSNQDGLGTESFPEDTFWPVHNFILQTL 79 
150007616   4 RKRALFIDRDGTLVKEPPVDYQLDSLEKLEFVPKVMRNLYFIrERLDFEFVMVSNQDGLGTPSFPEETFWPAHNLMLKTL 83 
187251126   3 NKKTLFIDRDGTLIFEPIATKQINSLDEMFFTKGVISALKRF-KQAGYSLVIVTNQDALGTPENPRKVYENINNKMFAIF 81 
212550390   2 KKRVLFIDRDGTLIIEPPITFQVNNLEELEFLPGVIRNLYFIrKHLNFELVMVTNQDGLGTPIYPQNNFDIVQKKMLNIF 81 
262341198  81 RTEGINFSSIHIDKTFPEEKSSTRKPEIGMLTSYLQSDLYNISKSFVIGDRLNDVFLAKNLGCKSIWIkenhhyknltke 160
54294141   79 SSQGILFDEIFICPHTPEDNCICRKPKTGLLESYLKETAFAKQYSWVIGDRDTDKEFADNLGVNFLPIs----------- 147
54297154   79 SSQGILFDEIFICPHTPEDNCICRKPKTGLLEPYLKETAFAKHYSWVIGDRDTDKEFADNLGVNFLPIs----------- 147
148358783  79 SSQGILFDEIFICPHTPEDNCICRKPKTGLLEPYLKETAFAKQYSWVIGDRDTDKEFADNLGVNFLPI------------ 146
296106828  79 SSQGILFDEIFICPHTPEDNCICRKPKTGLLEPYLKETAFAKQYSWVIGDRDTDKEFADNLGVNFLPIs----------- 147
52841430   79 SSQGILFDEIFICPHTPENNCICRKPKTGLLEPYLKETVFAKQYSWVIGDRDTDKEFADNLGVNFLPIs----------- 147
294673215  80 EGEGITFDEILIDPHFPEDNAPTRKPNIGLVEKYINNPDYDISNSYVIGDRETDRQFAQNIGCKSLIL------------ 147
150007616  84 EGEGIVFDDILIDPSFPEDNSPNRKPRTGMLTKYMTG-EYDLENSFVIGDRLTDMELAHNLGAKGIWLrpeegaesel-- 160
187251126  82 ASEDIFFNAVLECPHNKTDGCACRKPKTKLGVNYIKNNPVDLENSYMIGDRDTDVEFGENLGIKSFKL------------ 149
212550390  82 QNEGIFFDNIFIDKSFPQDNLSTRKPNTAMLTQYFSD-DYDLRSSYVIGDRLTDIELAKNLGCKAILLspktn------- 153
262341198 161 ekdyystieekdlkkiiSLKTDNWEDIYEYLLsiST-KRLV-HQRTTLETNVKISIFLNGKGRAHIQTGLGFFDHLLQQI 238
54294141  148 -------------------kTHTWEMVASAII--ND-ARKAsVQRKTKETAVDLSVQLDSDQTSVIDTPIPFFTHMLEQV 205
54297154  148 -------------------kTHTWEMVVSAII--ND-ARKAsVQRKTKETAIDLSVQLDSDQTSVIDTPIPFFTHMLEQV 205
148358783 147 ------------------SKTHTWKMVVSAII--ND-ARKAsVQRKTKETSIDLSVQLDSDQTSVIDTPIPFFTHMLEQV 205
296106828 148 -------------------kTHTWKMVVSAII--ND-ARKAsVQRKTKETSIDLSVQLDSDQTSVIDTPIPFFTHMLEQV 205
52841430  148 -------------------kTHTWEMVASAII--ND-ARKAsVQRKTKETTIDLSVQLDSDQTSVIDTPIPFFTHMLEQV 205
294673215 148 -----------------SDEGITWNKIAELLF---AgERIAeVKRTTKETDIWVKVNLDGSGKCDISTGLGFFDHMLEQI 207
150007616 161 --------aayatslspAYITDDWDKITEYLF--AG-ERRAvVRRATKETDIYVDWNLDGTGKTSISTGLGFFDHMLDQI 229
187251126 150 ------------------TKKLGWAEIAGEIL--DK-PRKAqVIRKTKETNIKLNLNLDGKGQTKSNTGIEFFDHCLDQL 208
212550390 154 ------------fipntALITINWDKISEFLV--VG-ERKAiVQRTTKETNIHVEINIDGKGKTDISTGLGFFNHLLAQI 218
262341198 239 AFHSSIDLNIQTKGDLYVDEHHTIEDTGIALGEIFDQALGNKKGIERYGFy-LIPMDDSLSTVALDIGGRSQLVWKTRFF 317
54294141  206 AKHGGFDLRLQASGDLEVDEHHLIEDTAIALGEAIRTALGDKWGINRYGY--TLPMDESLATIAIDISGRSFCDFKGQFT 283
54297154  206 AKHGGFDLRLQASGDLEVDEHHLIEDTAIALGEAIRTALGDKWGINRYGY--TLPMDESLACVAIDISGRSFCDFKGQFT 283
148358783 206 AKHGGFDLRLQASGDLEVDEHHLIEDTAIALGEAIRTALGDKWGINRYGY--TLPMDESLATIAIDISGRSFCDFKGQFT 283
296106828 206 AKHGGFDLRLQASGDLEVDEHHLIEDTAIALGEAIRTALGDKWGINRYGY--TLPMDESLATIAIDISGRSFCDFKGQFT 283
52841430  206 AKHGGFDLRLQASGDLEVDEHHLIEDTAIALGEAIRTALGDKWGINRYGY--TLPMDESLATIAIDISGRSFCDFKGQFT 283
294673215 208 GKHGMIDLTIHTKGDLEVDEHHTIEDTAIALGECILQALGDKRGIERYGY--CLPMDDCLCSACLDFGGRPWLVWDAEFH 285
150007616 230 GKHSGTDLTVRVKGDLEVDEHHTIEDTAIALGEAMLKALGDKRGIERYGY--CLPMDDCLCSVALDFGGRPWLVWDAEFH 307
187251126 209 GKHGGFDLQIKCKGDLCVDEHHTVEDTALALGQAFKTALGDKRGIERYAWeriLVMDDAKVEISIDISNRPYLVFKGKFD 288
212550390 219 GKHSGIDLIVKMKGDLNVDEHHTIEDTGIALGSALSQVLTDKRGIERYGF--CLPMDDCLCLAAVDFGGRAWFVWETEFH 296
262341198 318 REKIGKVPTEMFYHFFKSFSLSAKCNLYIHATGKNEHHKIESIFKCFAKALKMAIRKNy-SNnKIPSSKGLL 388
54294141  284 REFIGGMATEMIPHFFQSLSSALGATIHIEVTGINHHHMIEACFKVLGRALRQACSRT--NN-YLPSTKGVL 352
54297154  284 REFVGGMATEMVPHFFQSLSSALGATIHIEVTGTNHHHMIEACFKVLGRALRQACSRT--NN-YLPSTKGVL 352
148358783 284 REFIGGMATEMIPHFFQSLSSALGATIHIQVTGTNHHHMIEACFKVLGRALRQACSRT--NN-YLPSTKGVL 352
296106828 284 REFIGGMATEMIPHFFQSLSSALGATIHIQVTGTNHHHMIEACFKVLGRALRQACSRT--NN-YLPSTKGVL 352
52841430  284 REFIGGMATEMIPHFFQSLSSALGATIHIEVTGTNHHHMIEACFKVLGRALRQACSRT--NN-YLPSTKGVL 352
294673215 286 REKIGEMPTEMFLHFFKSLSDASKMNLNIKAEGQNEHHKIEGIFKALARALKMAIRRDiyHY-ELPSTKGML 356
150007616 308 REKVGDMPTEMFLHFFKSLSDAARMNLNIRAEGTNEHHKIEGIFKALARSIKMAIRRDi-YRfELPSTKGLL 378
187251126 289 REYAGKMPTELVEHFFESFVSASGINMNIKIEGKNTHHKIEACFKAFARVLRDAVKIT--GT-KVSSTKGIL 357
212550390 297 REKIGDMPTEMFPHFFKSLSDAAKINLIIKAKGQNEHHKIEGIFKSFARAIKMAIRRDi-FNyELPSTKGIL 367
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