2EBD,4DFE


Conserved Protein Domain Family
FabH

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COG0332: FabH 
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]
3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Statistics
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PSSM-Id: 440101
Aligned: 790 rows
Threshold Bit Score: 122.141
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2EBD_A         1 M-GTKIIGTGVYLPKNVLTNFDLEK----I-V-------D-------------T----S-------DE------WIT--- 34 
WP_015119120   4 Q-PVGIRAIALNFPSIIRTNDYYREnypeM-Vav----aEkktla---rlfapDg---Std---iwSQel--apYMSd-- 64 
WP_050433881   3 H-HAGLKSLAICSPSTLRTPDYWRKhhaqA-Vae----aEskslg---rlfagGs---Apst-dpfQIem--qpYLSt-- 65 
WP_014656547   2 L-SVGIQAVAIHLPEGLRTNAWWDKe---A-Its----sHsp---------kfSt---Hqhq-slyDKam--qpYLSd-- 55 
APR82468       2 Q-SIGILGLGTYLPPTVHTNDEWPA----SvVarwhermAhqatr----gdatAhevmS-------DGarktlaAMQeia 65 
NP_348630      8 NnYVKLLGIGACLPGNPIKFEDINN----Y-I-------G-------------Q----IpnapkkiKT------WISrvq 52 
WP_089609663   2 EkYVKLLATSSYLPGQPIKFDDINE----Y-L-------G-------------P----FtnapkkiKQ------WTEriq 46 
APR86005       3 T-PVGIRSLSVSFPSVLRTNDHFRKtrpeL-Vae----aEkaala----rlwkKq---Ggsg-aqfDAem--epYLGd-- 64 
WP_015191514   4 L-PVGIRSLAVSFPSIIRTNDYYREnypeL-Vaq----aEqktls---kvfstTn---Sdss-nefDRem--lpYLAd-- 66 
APR79637       4 R-DIGILGMGLW-EGEVITNDHYGD----RyLaraqvkdPyrgmrgddgtvriAgmvlSp------DRypraiaAIEqsf 71 
2EBD_A        35 ----TRTGIKERRIA-K------EETITYMATQAAKEALREANLSPEELDLIILATLTPQKRFPSTACLVQAQLKA-KGV 102
WP_015119120  65 ----PFRGTVERRVVaA------DETSLSLEYRAATDALEAANLAPEDIDLMLVTSLFPEQVTPGNAAFLAGKLGL--HN 132
WP_050433881  66 ----PFRGTVECRVLgP------EETPLSLELQAARGALAAAQLSPGDLDAIIVASFVPDRLFPGNAVFLARELGA--AA 133
WP_014656547  56 ----PFLGSVERRVVvN------HESASSLGIKAATKVLSAAKVAASDIDCLIVTSMFDDHIGCGDAGYIAQALGI--GG 123
APR82468      66 --gdPFRGAIERRWMdE------GTTVADMEAAAAREAMTRASVSPDRIDVILTQTSVPDHLFVNGASKTHHLLDLpRRC 137
NP_348630     53 pimkEMLGIDYCYYAfNgktrkfDEDNLSLSVKASKLALQDAKIKPQDIDLLIYA-GNYSYQMPPISTRIQEELGI-DIC 130
WP_089609663  47 pimkEMLGIEYCYYAfDnktrtfPEDNLTLSVKAAEKALAEAGLEAKDIDLLIYG-GAYSHQLPPLSTRIQEALGI-ERC 124
APR86005      65 ----PFRGTRYRRVLgP------DETCLSLEIRAARQALEAAALRPSDIDCMIVASFLPMQPGVGNAAFLAGALDY--EG 132
WP_015191514  67 ----PFRGTVERRVFaP------GESALTISYQAAKDAIAAAKLTAEDIDLMLVGTIFTDQLGPGNAAFLAEKLGL--QG 134
APR79637      72 --rdPYRGTLRRRLFpH------DLKVSDAETEAARKAIADAGLTPADIDAVLVQSFLPDQFQPKNSAIIAHNLGI-RHA 142
2EBD_A       103 YAFDISAACSGFIYALDIADSFIKSGKAKNVLVIGAEKLSEAV----------DWEDRSTCVLFGDGAGAVVVTRSEd-K 171
WP_015119120 133 AAWNIESTCTSALVSLQTACSLVRTGEYRNVLVVVSTTYSRYT----------DEND-TLAFLSGDGAGAFVVGSLKq-N 200
WP_050433881 134 PAWNLESTCTGAIVGLQSASALIQAGAYRNVLLVSSCSYSRML----------ELSD-SLSWFMGDGAGALVLGEVPe-P 201
WP_014656547 124 GAFNIGATCNSSMSALLTACGLVSSGLNNKVLVIATALFSRAL----------DDDN-AAMRFHGDASTAFIVGPVKe-G 191
APR82468     138 LAVATDVAANGLGTHAALAQALIASGRARHVLSVHSSAMSRVI----------RKEE-PDSVLWGDGAAAVVFGPVGa-G 205
NP_348630    131 SEYHIHSNCSSIYKAIKLADTFLKSGEYKNALVVSSMVSSAHFipeyynqqkvTKEDVFLRWYLCDGAGAVVLSSKDtvD 210
WP_089609663 125 GEFHIHSNCTSVYKGLKLAHSLLKTGEYKNALVVSSIVVSSCFipefynqekiTKEDIFLRWYLCDGAGAFVLSAEDekD 204
APR86005     133 AAYNLESACTSAAVATQSAVALIRAGECERVLVVVSCTYSRVS----------DDRD-SLCWFLGDGAGAYVVSAVPe-G 200
WP_015191514 135 AAWNLESTCSSAVAALQTASAMVQTRQYHNVLVVICTNYSPLT----------DPQD-TLSFLSGDGAGAFVVSQLKp-N 202
APR79637     143 PAWEIDSICNSALIHLTVGSSLIVSGFGRHILCVQSTAYSRVS----------DPAS-STNIQDADLASAFVLGPSPg-T 210
2EBD_A       172 SDILATRM----YAEG---SLEELLHADNC---G------------------------Y-IRM-------KGRELFKVAV 209
WP_015119120 201 QGVLGSKIantaATCG---AFYNEFTTDeqg-------------------------niK-MFIrgg--kgASKMFNETTV 249
WP_050433881 202 YGVLGTKLvntqSTCG---AFGTGVKLDedg-------------------------raV-FRMwsg-deeAARRMRDDAA 251
WP_014656547 192 YGLLGSKSlhlgETCG---TWCFKVVEDqys-------------------------ptA-QHIrlsfnkpVTHVLRSTAE 242
APR82468     206 KGLLGADH----NTDG---ENHEALVL------Gvpgrcww-----------ddgaitV-CSTda----aRVRAMLLTLV 256
NP_348630    211 N---GFYL----KNTYvesAGGKKESVm-----GnnfpsyfsnpltayengehhirqvtldkM-------RKYVVDENGK 271
WP_089609663 205 H---GFYL----ENTYvesSGGKKMSAm-----CndypylwnnplldyencahhirqlylneL-------KDHALEENGK 265
APR86005     201 QGVLGMKIvntsKTCN---TFYYDLHDHptr-------------------------gpM-IRIgah--erTGRVLGQVSG 249
WP_015191514 203 QGVLGTKIlntaCTCN---TFYNELVMDaeg-------------------------kpH-IYIraa--kgTGKILSDTAT 251
APR79637     211 E--MAVSW----RTDG---RLHGAIRLaWGtpgGepparww-----------ersperLqIRFdp----aLQEEVMSEIA 266
2EBD_A       210 RSMEEVCREVLEKAGVKPEEVSLVIPHQANVRIINALAEK---LNIPKEKVFVNIQKYGNTSAASIPIALHEAIKEGKVK 286
WP_015119120 250 KFIRLCCHGAIASADVSLEDIDFFAFNTPSAWYSRVCTRA---LGIDPNRTINLNPLYANIGPTFPIANLYHAAESGKIR 326
WP_050433881 252 SQLEASVAGVTAATGVALEDIDFFVFNTPTAWFASFCARV---LGISSERTISVYPRYGNIGAALMMANLFHAAHEKKIA 328
WP_014656547 243 YYLKQTVKGALAKAKLSINDIDCVALNAPTAWHAEFSANV---LGIETKRVINTFPQFAYNGPAMMPIHLYTAAIQKSIK 319
APR82468     257 DRARDSISGSLADAGITAGEVDFYASHQGAAWLPRVSAEH---AGLGAAKTLATFPRFGNMNSVNVPFVLATAEREGRIR 333
NP_348630    272 TIFYNALKRMLDKQKIDLSTLKYFMVNMPSKFVREYITNEcvgLGISPDKFYSVSQKIGYAGPPAAIISLDRLLKNNDFK 351
WP_089609663 266 TIFYNALKRMLDSQHIDLSSLRYFVVNMPSRAVRDYITQEcteFFIDLNKFYSAIEDVGYAGPPAAIISMDILLKNHTFQ 345
APR86005     250 PYLVECCDGALAQAGLTRDDVRFFVFNTPTAWYGRFCAQA---LGVSPERTIDTYPEYANIGPALMPVNLYTAARAGRIA 326
WP_015191514 252 EFLKKCCDGAVKAAGVTLKDIDFFAFNTPTAWYADVCARA---LGISKEHTINLNHLYANIGPTFPLANLYHGVESGKIR 328
APR79637     267 GNAKTVCDEALQRAGMRSDDLETFIAHQPMSWNKAFMEDV---LSLEDGVAYDTFEEYACINSVGIPASIYEARRSGRIK 343
2EBD_A       287 RGDLILMTAMGGG-LTWGAVLLRY 309
WP_015119120 327 ENDLVLVYTMGSS-SNAGASVMRW 349
WP_050433881 329 AGDLVLLYGVGSV-STAGATLVRW 351
WP_014656547 320 PGGIMLLYAYGGQ-TEASAAVLRW 342
APR82468     334 DGSLVVTFGGGLG-EAWSSLCLRW 356
NP_348630    352 NNDLIFSFVLEVSkFMQGGFTIQY 375
WP_089609663 346 NNDLIFSFVMEVSkYMQGGFTLRY 369
APR86005     327 PGDVVLVYTIGSV-STAGAVVMRW 349
WP_015191514 329 ENDLVLVYTIGSV-SNAGACVMRW 351
APR79637     344 RGSNVLLFGPAAG-YTYAAAAIRW 366
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