Conserved Protein Domain Family
PRK08299

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PRK08299: PRK08299 
NADP-dependent isocitrate dehydrogenase
Statistics
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PSSM-Id: 236226
Aligned: 196 rows
Threshold Bit Score: 742.443
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
262341048   1 MKKIKVNNPIVEIDGDEMARVMWKYIKKYFIFPYLDINIIYFDLGIENRNLTNDQITIDAAYAIKKYNVGIKCATITPDE 80 
24216766    1 MAKIKVKTPLVELDGDEMTRIIWKEIKDRFIHPYLDIELDYYDLGVEYRDKTDDKVTVDSAHAIQKYGVGVKCATITPNQ 80 
45659065    1 MAKIKVKTPLVELDGDEMTRIIWKEIKDRFIHPYLDIELDYYDLGVEYRDKTDDKVTVDSAHAIQKYGVGVKCATITPNQ 80 
116329407   1 MAKIKVKTPLVELDGDEMTRIIWKEIKDRFIHPYLDIELDYYDLGVENRDKTEDKVTVDSAHAIQKYGVGVKCATITPNQ 80 
116329990   1 MAKIKVKTPLVELDGDEMTRIIWKEIKDRFIHPYLDIELDYYDLGVEHRDKTEDKVTVDSAHAIQKYGVGVKCATITPNQ 80 
148270724   1 MEKIKVKNPIVELDGDEMARVMWKMIKEKLILPYLDVQLVYFDLGIKKRDETDDQITIEAAKAIKKYGVGVKCATITPDA 80 
183222240   1 MGKIKVKTPLVELDGDEMTRIIWKEIKDRFIHPYLDITLEYYDLGVEYRDKTDDQVTVDSANAIKKHGVGVKCATITPNA 80 
222100401   1 MEKIKVKNPIVELDGDEMARVMWKMIKEELILPYLDIPLIYFDLGIKKRDETDDQITIEAAKAIKKYGVGVKCATITPDA 80 
170289448   1 MEKIKVKNPIVELDGDEMARVMWKMIKEKLILPYLDIQLVYFDLGIEKRDETDDQITIEAAKAIKKYGVGVKCATITPDA 80 
281413029   1 MEKIKVKNPIVELDGDEMARVMWKMIKEKLILPYLDVQLVYFDLGIKKRDETDDQITIEAAKAIKKYGVGVKCATITPDA 80 
262341048  81 NRMKEFHLKKMWKSPNGTIRNIVNGTVFREPIIANNISRFIPNWKNPICIARHAYADQYDAVDFIVEEKGKLYIYFIPDN 160
24216766   81 DRVKEYNLKQEWKSPNGTIRSILDGTVFRKPIIVKNIPPAVRSWKKPITVGRHAYGDLYKDTELYIPEAGKVELVYTGKD 160
45659065   81 DRVKEYNLKQEWKSPNGTIRSILDGTVFRKPIIVKNIPPAVRSWKKPITVGRHAYGDLYKDTELYIPEAGKVELVYTGKD 160
116329407  81 DRVKEYNLKQEWKSPNGTIRSILDGTVFRKPIIVKNIPPAVRSWKKPITVGRHAYGDLYKDTELYIPEAGKVELVYTGKD 160
116329990  81 DRVKEYNLKQEWKSPNGTIRSILDGTVFRKPIIVKNIPPAVRSWKKPITVGRHAYGDLYKDTELYIPEAGKVELVYTGKD 160
148270724  81 ERVKEYNLKKAWKSPNATIRAYLDGTVFRKPIMVKNVPPLVKRWKKPIIIGRHAYGDIYNAVEVKVEGPAEVELVVRNk- 159
183222240  81 DRVKEYNLKQEWKSPNGTIRAILDGTVFRKPIIIKNIPAAVNSWKKPIAIGRHAYGDIYRDVEISVDGPGKVELVYTDAS 160
222100401  81 ERVKEYNLKKAWKSPNATIRAYLDGTVFRKPIMVKNVPPLVKRWKKPIIIGRHAYGDIYNAVEAKVEGPAEVELVVKNr- 159
170289448  81 ERVKEYNLKKAWKSPNATIRAYLDGTVFRKPIMVKNVPPLVKRWKKPIIIGRHAYGDIYNAVEAKVEGPAEVELVVRNk- 159
281413029  81 ERVKEYNLKKAWKSPNATIRAYLDGTVFRKPIMVKNVPPLVKRWKKPIIIGRHAYGDIYNAVEVKVEGPAEVELVVRNk- 159
262341048 161 NknKSKKFEIHHFTEPGVAMGMYNTDQSIYGFARSCFNYSIYKKWPLFLSTKNTILKAYDEKYKKIFQDLYEGEyKSKFK 240
24216766  161 Gk-EKQRALIHDFEGAGVIMGQHNLDKSILSFAQACFNYAISEKIDLWFATKDTISKKYHARFRAIFDELAKAK-AADLK 238
45659065  161 Gk-EKQRALIHDFEGAGVIMGQHNLDKSILSFAQACFNYAISEKIDLWFATKDTISKKYHARFRAIFDELAKAK-AADLK 238
116329407 161 Gk-EKQRALIHDFDGAGVIMGQHNLDKSILSFAQACFNYAISEKIDLWFATKDTISKKYHARFRAIFDELARAK-AGDLK 238
116329990 161 Gk-EKQRALIHDFDGAGVIMGQHNLDKSILSFAQACFNYAISEKIDLWFATKDTISKKYHARFRAIFDELARAK-AGDLK 238
148270724 160 ---ENKTLLVHKFEGNGVVMAMHNLEKSIRSFAQSCINYAISEKVDIWFATKDTISKVYHAYFKDIFQEEVDKR-KEELE 235
183222240 161 Gn-EKQRLLVNEFKGSGVALAMHNLDESIKSFAKACFNYALSEKISIWFATKDTISKKYHARFRDIFDTMAKEQ-DAAMK 238
222100401 160 ---ENKVLLVHRFEGNGVVMAMHNLEKSIRSFARSCINYAISEKVDIWFATKDTISKVYHAYFKDIFQEEVDRR-KEDLE 235
170289448 160 ---ENKTLLVHKFEGNGVVMAMHNLEKSIRSFAQSCINYAISEKVDIWFATKDTISKVYHAYFKDIFQEEVDKR-KEELE 235
281413029 160 ---ENKTLLVHKFEGNGTVMAMHNLEKSIRSFAQSCINYAISEKVDIWFATKDTISKVYHAYFKDIFQEEVDKR-KEELE 235
262341048 241 KLKITYEHRLIDDMIAKTIKSNGGFIWACKNYDGDVQSDCIAQGFGSLGMMTSVLLTPDGKtLESEAAHGTITRHYRLYQ 320
24216766  239 KAGIEYSYYLIDDAVAQLMKNEGGMLWALMNYDGDVMSDMVASGFGSLGLMTSVLVSPDGK-FEYEAAHGTVTRHYRKYQ 317
45659065  239 KAGIEYSYYLIDDAVAQLMKNEGGMLWALMNYDGDVMSDMVASGFGSLGLMTSVLVSPDGK-FEYEAAHGTVTRHYRKYQ 317
116329407 239 KAGIEYSYYLIDDAVAQIMKNEGGMLWALMNYDGDVMSDMVASGFGSLGLMTSVLVSPDGK-FEYEAAHGTVTRHYRKYQ 317
116329990 239 KAGIEYSYYLIDDAVAQIMKNEGGMLWALMNYDGDVMSDMVASGFGSLGLMTSVLVSPDGK-FEYEAAHGTVTRHYRKYQ 317
148270724 236 KAGVNYRYMLIDDAAAQILRSEGGMLWACMNYEGDIMSDMIASGFGSLGLMTSVLVSPDGV-YEFEAAHGTVRRHYYRYL 314
183222240 239 AAGITYSYYLIDDAVAQIMKNEGGQLWALMNYDGDVMSDMVASGFGSLGLMTSVLVSPDGK-YEYEAAHGTVTRHYRKYQ 317
222100401 236 KAGVNYRYMLIDDAAAQILRSEGGMLWACMNYEGDIMSDMIAAGFGSLGLMTSVLVSPDGV-YEFEAAHGTVRRHYYRYL 314
170289448 236 KAGVNYRYMLIDDAAAQILRSEGGMLWACMNYEGDIMSDMIASGFGSLGLMTSVLVSPDGI-YEFEAAHGTVRRHYYRYL 314
281413029 236 KAGVNYRYMLIDDAAAQILRSEGGMLWACMNYEGDIMSDMIASGFGSLGLMTSVLVSPDGV-YEFEAAHGTVRRHYYRYL 314
262341048 321 ERKKTSTNPIASIFSWTRGLKHRAFLDKNMDLKYFSEKMEKTCINFIESGKMTKDLFQLVDgskynKKKNYLDTKTFLQE 400
24216766  318 QGETTSTNSVASIFAWTGALIKRGELDGTPDVVAFGHKLEKAVIDTIESGEMTKDLTLLCTd----SNAKALDTFQFMEA 393
45659065  318 QGETTSTNSVASIFAWTGALIKRGELDGTPDVVAFGHKLEKAVIDTIESGEMTKDLTLLCTd----SNAKALDTFQFMEA 393
116329407 318 QGETTSTNSVASIFAWTGALIKRGELDGTPDVVAFGHKLEKAVIDTIESGQMTKDLTLLCTd----PNAKALDTFQFMEA 393
116329990 318 QGETTSTNSVASIFAWTGALIKRGELDGTPDVVAFGHKLEKAVIDTIESGQMTKDLTLLCTd----PNAKALDTFQFMEA 393
148270724 315 KGEKTSTNPTASIFAWTGAIRKRGELDGTPEVCEFADKLEKAVINTIESGVITKDLQPFTEp----SIDKYVTLEEFIDE 390
183222240 318 KGETTSTNSVASIFAWTGALAKRGELDGTPDVVNFAHKLEEAIIETIEGGEMTKDLLSLSTa----AKKTELDTFQFMEA 393
222100401 315 KGEKTSTNPTASIFAWTGAIRKRGELDNTPEVCDFADKLEKAVINTIESGVITKDLQPFTDp----PIDRYVTLEEFIKE 390
170289448 315 KGEKTSTNPTASIFAWTGAIRKRGELDGTPEVCEFADKLEKAVINTIESDVITKDLQPFTEp----PIDKYVTLEEFIDE 390
281413029 315 KGEKTSTNPTASIFAWTGAIRKRGELDGTPEVCEFADKLEKAVINTIESGVITKDLQPFTEp----PIDKYVTLEEFIDE 390
262341048 401 LRIFFDKKM 409
24216766  394 IQKRL---- 398
45659065  394 IQKRL---- 398
116329407 394 IQKKL---- 398
116329990 394 IQKKL---- 398
148270724 391 VKKNLEKLL 399
183222240 394 VQKRLDAKL 402
222100401 391 VKKNLEELL 399
170289448 391 VKKNLEKLL 399
281413029 391 VKKNLEKLL 399
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