Conserved Protein Domain Family
thrB_alt
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TIGR00938: thrB_alt 
homoserine kinase, Neisseria type
Homoserine kinase is required in the biosynthesis of threonine from aspartate.The member of this family from Pseudomonas aeruginosa was shown by direct assay and complementation to act specifically as a homoserine kinase. [Amino acid biosynthesis, Aspartate family]
Links
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Statistics
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PSSM-Id: 273351
Aligned: 4 rows
Threshold Bit Score: 525.135
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAC70365       1 MAVYTSVSDEEVSSFLDLYpDSGRLLSIKGITEGVENSNYLITTDVRSYILTLYEKRVnPEELPFFMALTDHLAAENLPV 80  Zymomonas mobil...
AAF21132       1 MSVFTTVSFEQMQQWLKGY-DLGELLDLQGIASGITNTNYFVTTDNGRYVLTLFEEHS-AEELPNFLDLMTHLAERGIPC 78  Methylobacillus...
WP_010921193   1 MAVYTDITDQELEAFLEGY-DLGAPLAFKGIAEGVENSNFLLETEKGRYILTVYERRVkAEDLPYFLNMLTWLADRGYPS 79  Caulobacter vib...
WP_002218156   1 MSVYTSVSDDEMRGFLSGY-DLGEFVSLQGIAQGITNSNYFLTTTSGRYVLTVFEVLk-QEELPFFLELNRHLSMKGVAV 78  Neisseria menin...

AAC70365      81 PKAWKSRDGKQIQTLAGRPACLIEFLQG--VGRPPLMRNRPVLPVKCWVKMHKslTHFSENRKNsLDLENWHILAEKCgf 158 Zymomonas mobil...
AAF21132      79 PHPVKNNAGRALGELNGKPAALVSCLAGrsLDNPMPQHCAAIGEVLARMHIAG--ASFKAGMSN-LRGQEWRIATAAK-- 153 Methylobacillus...
WP_010921193  80 ARPIPTRSGATLSSLRGKPAAIVEFLPGlsVRKPTAAHCREAGEGLAWLHLAG--EGYPGRRANdLGQAAWSPLFSKHr- 156 Caulobacter vib...
WP_002218156  79 AAPVARKDGRLDSVLAGKPACLVACLKGsdTALPTAEQCFHTGAMLAKMHLAA--ADFPLEMEN-PRYNAWWTEACAR-- 153 Neisseria menin...

AAC70365     159 eAMNQIEAHMGDEVKKELDYLDKFWPKDLPRSVIHADLFPDNVLFEGDS-LKGVIDFYFACTEVRAWDLAITYSAWCFDQ 237 Zymomonas mobil...
AAF21132     154 -VAPFLDEENHRMLDAQLEFERTFDTRRLPRGVIHADLFRDNVLMDGDK-VGGVIDFYYACHDALLYDIAIAVNDWCVNA 231 Methylobacillus...
WP_010921193 157 kAAEDLKPGLSATIDNDLAQLSLMWPRNLPTGTIHADYFPDNVFFQSNGkFAAAIDFYFACDDAYAYDVAVTLNAWCFEA 236 Caulobacter vib...
WP_002218156 154 -LLPVLSQDDAALLCSEIDALKDNLGNHLPSGIIHADLFKDNVLLDGGQ-VSGFIDFYYACRGNFMYDLAIAVNDWARTA 231 Neisseria menin...

AAC70365     238 EDHFLADHAKALIKGYHQSFALTEEERAAFIVLLRGAALRFLLTRAWDWVNTPPDALVVPKDPRDFFKRLRF 309 Zymomonas mobilis subsp...
AAF21132     232 DCTLDAVRVRAFLDAYHAIRPLTGEEHAAWPGMLRVAAMRFCVSRLNDLYFPQAGELTHAKDPAYFERILKH 303 Methylobacillus flagell...
WP_010921193 237 DGSFNITAAKALLNGYERRRPLSPIEKEALPILARGAAMRFFLTRLADWGSTPAGALVRPKDPLEYERKLAV 308 Caulobacter vibrioides
WP_002218156 232 DNKLDEALKKAFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSRLLDFHFPQAGEMTFIKDPNAFRNLLLS 303 Neisseria meningitidis
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